TI-205 nuclear magnetic resonance determination of the thermodynamic parameters for the binding of monovalent cations to gramicidins A and C. Academic Article uri icon

Overview

abstract

  • Thermodynamic parameters for the binding of the monovalent cations, Li+, Na+, K+, Rb+, Cs+, NH4+, TI+, and Ag+, to gramicidin A and for the binding of TI+ to gramicidin C, incorporated into lysophosphatidylcholine, have been determined using a combination of TI-205 nuclear magnetic resonance spectroscopy and competition binding. The thermodynamic parameters, enthalpy and entropy, are discussed in terms of a process involving the transfer of cations from an aqueous to amide environment.

publication date

  • September 1, 1988

Research

keywords

  • Gramicidin
  • Ion Channels
  • Models, Biological

Identity

PubMed Central ID

  • PMC1330351

Scopus Document Identifier

  • 0023680895

Digital Object Identifier (DOI)

  • 10.1016/S0006-3495(88)82985-0

PubMed ID

  • 2462930

Additional Document Info

volume

  • 54

issue

  • 3