Biophysical journal
Journal
Overview
publication venue for
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Molecular simulations and NMR reveal how lipid fluctuations affect membrane mechanics..
122.
2022
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Conformational transitions in BTG1 antiproliferative protein and their modulation by disease mutants..
121.
2022
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Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning..
120.
2021
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Conserved allosteric ensembles in disordered proteins using TROSY/anti-TROSY R2-filtered spectroscopy..
120.
2021
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Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide..
120.
2021
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Extreme Antagonism Arising from Gene-Environment Interactions..
119.
2020
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Molecular Mechanism for Gramicidin Dimerization and Dissociation in Bilayers of Different Thickness..
117.
2019
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Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles..
116.
2019
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A New Computational Method for Membrane Compressibility: Bilayer Mechanical Thickness Revisited..
116.
2019
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Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes..
115.
2018
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Accurate In Silico Modeling of Asymmetric Bilayers Based on Biophysical Principles..
115.
2018
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Fluorinated Alcohols' Effects on Lipid Bilayer Properties..
115.
2018
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A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein Fibrils..
114.
2018
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Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter..
114.
2017
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Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties..
113.
2017
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Lysenin Toxin Membrane Insertion Is pH-Dependent but Independent of Neighboring Lysenins..
113.
2017
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Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation..
113.
2017
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Influence of Protein Scaffold on Side-Chain Transfer Free Energies..
113.
2017
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Introduction to Biophysics Week: What is Biophysics?.
112.
2017
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Gramicidin A Channel Formation Induces Local Lipid Redistribution I: Experiment and Simulation..
112.
2017
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Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model..
112.
2017
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Glycan Determinants of Heparin-Tau Interaction..
112.
2017
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The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel..
111.
2016
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Illuminating Myocyte-Fibroblast Homotypic and Heterotypic Gap Junction Dynamics Using Dynamic Clamp..
111.
2016
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Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers..
111.
2016
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Multiscale Simulations Reveal Key Aspects of the Proton Transport Mechanism in the ClC-ec1 Antiporter..
110.
2016
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Direct Measurement of the Structure of Reconstituted High-Density Lipoproteins by Cryo-EM..
110.
2015
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Predicting first traversal times for virions and nanoparticles in mucus with slowed diffusion..
109.
2015
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Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis..
108.
2015
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Structural, mechanical, and dynamical variability of the actin cortex in living cells..
108.
2015
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Synaptic activity regulates the abundance and binding of complexin..
108.
2015
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Quantifying the entropy of binding for water molecules in protein cavities by computing correlations..
108.
2015
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Tau binds to lipid membrane surfaces via short amphipathic helices located in its microtubule-binding repeats..
107.
2014
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Light harvesting by lamellar chromatophores in Rhodospirillum photometricum..
106.
2014
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Voltage and calcium dynamics both underlie cellular alternans in cardiac myocytes..
106.
2014
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Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay..
106.
2014
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Ion-induced defect permeation of lipid membranes..
106.
2014
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Active-site structure of the thermophilic Foc-subunit ring in membranes elucidated by solid-state NMR..
106.
2014
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Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow..
106.
2014
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Optoporation and genetic manipulation of cells using femtosecond laser pulses..
105.
2013
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Small-molecule photostabilizing agents are modifiers of lipid bilayer properties..
104.
2013
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Ion-controlled conformational dynamics in the outward-open transition from an occluded state of LeuT..
103.
2012
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Multi-ion distributions in the cytoplasmic domain of inward rectifier potassium channels..
103.
2012
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Residues at the outer mouth of Kir1.1 determine K-dependent gating..
102.
2012
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Influence of hydrophobic mismatch on structures and dynamics of gramicidin a and lipid bilayers..
102.
2012
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Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation..
101.
2011
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Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors..
101.
2011
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Alcohol's effects on lipid bilayer properties..
101.
2011
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Modulation of Kir1.1 inactivation by extracellular Ca and Mg..
100.
2011
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Conformational rearrangements to the intracellular open states of the LeuT and ApcT transporters are modulated by common mechanisms..
99.
2010
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Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios..
99.
2010
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Anthropomorphizing the mouse cardiac action potential via a novel dynamic clamp method..
97.
2009
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Energy transfer in light-adapted photosynthetic membranes: from active to saturated photosynthesis..
97.
2009
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Modeling membrane deformations and lipid demixing upon protein-membrane interaction: the BAR dimer adsorption..
97.
2009
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Contact-mode high-resolution high-speed atomic force microscopy movies of the purple membrane..
97.
2009
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An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1..
97.
2009
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Structural information, resolution, and noise in high-resolution atomic force microscopy topographs..
96.
2009
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Mitigating unwanted photophysical processes for improved single-molecule fluorescence imaging..
96.
2009
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Cardiac myocyte excitation by ultrashort high-field pulses..
96.
2009
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Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework..
94.
2008
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Protein diffusion on charged membranes: a dynamic mean-field model describes time evolution and lipid reorganization..
94.
2007
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Rows of ATP synthase dimers in native mitochondrial inner membranes..
93.
2007
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Action potential duration dispersion and alternans in simulated heterogeneous cardiac tissue with a structural barrier..
92.
2006
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Lateral organization in lipid-cholesterol mixed bilayers..
92.
2006
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Dynamics and diffusion in photosynthetic membranes from rhodospirillum photometricum..
91.
2006
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Localization of the pH gate in Kir1.1 channels..
91.
2006
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The DNA binding activity of p53 displays reaction-diffusion kinetics..
91.
2006
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Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy..
90.
2006
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Role of conserved glycines in pH gating of Kir1.1 (ROMK)..
90.
2006
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Ion permeation through a narrow channel: using gramicidin to ascertain all-atom molecular dynamics potential of mean force methodology and biomolecular force fields..
90.
2006
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Detection of forces and displacements along the axial direction in an optical trap..
90.
2005
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Action potential morphology influences intracellular calcium handling stability and the occurrence of alternans..
90.
2005
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pH dependence of amide chemical shifts in natively disordered polypeptides detects medium-range interactions with ionizable residues..
89.
2005
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Structural locus of the pH gate in the Kir1.1 inward rectifier channel..
88.
2005
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Liganded hemoglobin structural perturbations by the allosteric effector L35..
88.
2004
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A single-molecule technique to study sequence-dependent transcription pausing..
87.
2004
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Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels..
86.
2004
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Liquid-liquid phase separation in hemoglobins: distinct aggregation mechanisms of the beta6 mutants..
86.
2004
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Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex..
84.
2003
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Role of hyperpolarization-activated currents for the intrinsic dynamics of isolated retinal neurons..
84.
2003
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Cholesterol-induced protein sorting: an analysis of energetic feasibility..
84.
2003
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MC-PHS: a Monte Carlo implementation of the primary hydration shell for protein folding and design..
84.
2003
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Permeant cations and blockers modulate pH gating of ROMK channels..
84.
2003
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Probing protein-DNA interactions by unzipping a single DNA double helix..
83.
2002
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Regulation of ROMK by extracellular cations..
80.
2001
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Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature..
79.
2000
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Molecular dynamics simulations predict a tilted orientation for the helical region of dynorphin A(1-17) in dimyristoylphosphatidylcholine bilayers..
79.
2000
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The use of pHluorins for optical measurements of presynaptic activity..
79.
2000
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Binding mechanisms of TATA box-binding proteins: DNA kinking is stabilized by specific hydrogen bonds..
78.
2000
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Stretching of single collapsed DNA molecules..
78.
2000
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Ca2+-dependent gating mechanisms for dSlo, a large-conductance Ca2+-activated K+ (BK) channel..
76.
1999
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The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions..
76.
1999
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Structural determinants of gating in inward-rectifier K+ channels..
76.
1999
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Electrostatically balanced subnanometer imaging of biological specimens by atomic force microscope..
76.
1999
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Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channels..
76.
1999
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Estimating the persistence length of a worm-like chain molecule from force-extension measurements..
76.
1999
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Interaction of alpha-tocopherol with model human high-density lipoproteins..
75.
1998
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Selective binding of the TATA box-binding protein to the TATA box-containing promoter: analysis of structural and energetic factors..
75.
1998
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Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog..
75.
1998
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A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif..
75.
1998
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Progressive DNA bending is made possible by gradual changes in the torsion angle of the glycosyl bond..
74.
1998
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Energetics of inclusion-induced bilayer deformations..
74.
1998
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Structure and dynamics of calmodulin in solution..
74.
1998
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Asymmetrical distribution of Ca-activated Cl channels in Xenopus oocytes..
74.
1998
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Surface properties of native human plasma lipoproteins and lipoprotein models..
74.
1998
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Gramicidin channel kinetics under tension..
74.
1998
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Electroporation-induced formation of individual calcium entry sites in the cell body and processes of adherent cells..
73.
1997
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Gramicidin channels in phospholipid bilayers with unsaturated acyl chains..
73.
1997
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Does TATA matter? A structural exploration of the selectivity determinants in its complexes with TATA box-binding protein..
73.
1997
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Ionization, partitioning, and dynamics of tryptophan octyl ester: implications for membrane-bound tryptophan residues..
73.
1997
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Spontaneous transfer of monoacyl amphiphiles between lipid and protein surfaces..
72.
1997
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Stretching DNA with optical tweezers..
72.
1997
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13C NMR of Nephila clavipes major ampullate silk gland..
71.
1996
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Photophysics of a neurotransmitter: ionization and spectroscopic properties of serotonin..
71.
1996
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Environments of the four tryptophans in the extracellular domain of human tissue factor: comparison of results from absorption and fluorescence difference spectra of tryptophan replacement mutants with the crystal structure of the wild-type protein..
69.
1995
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Intracellular calcium levels correlate with speed and persistent forward motion in migrating neutrophils..
68.
1995
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Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue..
66.
1994
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Evidence of an associative intermediate on the myoglobin refolding pathway..
65.
1993
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A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels..
62.
1992
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Amino acid substitutions and ion channel function. Model-dependent conclusions..
62.
1992
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Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains..
62.
1992
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Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues..
62.
1992
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The role of Pro/Hyp-kinks in determining the transmembrane helix length and gating mechanism of a [Leu]zervamicin channel..
62.
1992
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On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer..
61.
1992
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Gramicidins A, B, and C form structurally equivalent ion channels..
58.
1990
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Gramicidin single-channel properties show no solvent-history dependence..
57.
1990
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Interactions of amiloride and small monovalent cations with the epithelial sodium channel. Inferences about the nature of the channel pore..
55.
1989
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Thermodynamic parameters for the binding of divalent cations to gramicidin A incorporated into a lipid environment by Tl-205 nuclear magnetic resonance..
55.
1989
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TI-205 nuclear magnetic resonance determination of the thermodynamic parameters for the binding of monovalent cations to gramicidins A and C..
54.
1988
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23Na-nuclear magnetic resonance investigation of gramicidin-induced ion transport through membranes under equilibrium conditions..
53.
1988
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On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study..
51.
1987
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Equilibrium binding constants for the group I metal cations with gramicidin-A determined by competition studies and T1+-205 nuclear magnetic resonance spectroscopy..
50.
1986
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Single-channel studies on linear gramicidins with altered amino acid side chains. Effects of altering the polarity of the side chain at position 1 in gramicidin A..
49.
1986
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Equilibrium binding constants for Tl+ with gramicidins A, B and C in a lysophosphatidylcholine environment determined by 205Tl nuclear magnetic resonance spectroscopy..
49.
1986
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Structural information from functional measurements: single-channel studies on gramicidin analogues..
49.
1986
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Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11..
45.
1984
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Nonequilibrium thermodynamic model of the rat proximal tubule epithelium..
44.
1983
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Ion movement through gramicidin A channels. Interfacial polarization effects on single-channel current measurements..
41.
1983
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Ion movement through gramicidin A channels. Single-channel measurements at very high potentials..
41.
1983
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Ion movement through gramicidin A channels. Studies on the diffusion-controlled association step..
41.
1983
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Lipoprotein Lipase Interaction with Synthetic N-Dansyl Fragments of Apolipoprotein C-II..
37.
1982
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Mechanism of association of human plasma apolipoproteins with dimyristoylphosphatidylcholine: effect of lipid clusters on reaction rates..
37.
1982
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Thermodynamics of lipid-protein association in human plasma lipoproteins..
37.
1982
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Coupled water transport in standing gradient models of the lateral intercellular space..
35.
1981
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Structural dynamics of liganded myoglobin..
32.
1980
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A method of nonlinear analysis in the frequency domain..
29.
1980
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Electrolyte transport across a simple epithelium. Steady-state and transient analysis..
27.
1979
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On the adsorption of phloretin onto a black lipid membrane..
25.
1979
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Electrostatic interactions among hydrophobic ions in lipid bilayer membranes..
21.
1978
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Potential energy barriers to ion transport within lipid bilayers. Studies with tetraphenylborate..
15.
1975
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A New Computational Method for Membrane Compressibility: Bilayer Mechanical Thickness Revisited..
117.
2019
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High-speed atomic force microscopy tracks toxin action.
2013
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Direct measurement of the mechanical properties of lipid phases in supported bilayers.
2012
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Direct measurements of torque during Holliday junction migration.
2011
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Experimental evidence for membrane-mediated protein-protein interaction.
2010
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External K activation of Kir1.1 depends on the pH gate.
2007
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Models for gramicidin channels.
1992
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Dimer versus tetramer.
1992
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A comment on nonlinear analysis.
1981
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Introduction to Biophysics Week: What is Biophysics?.
110.
2016
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Not just an oil slick: how the energetics of protein-membrane interactions impacts the function and organization of transmembrane proteins.
2014
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Sequencing and the single channel.
1999
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