Sugar and Alzheimer's disease: a bittersweet truth. uri icon

Overview

abstract

  • Reductions in brain glucose metabolism have long been associated with Alzheimer’s disease. A study now demonstrates that the endothelial glucose transporter GLUT1 is vital for maintaining brain energy metabolism and vascular clearance of amyloid-β.

publication date

  • April 1, 2015

Research

keywords

  • Alzheimer Disease
  • Amyloid beta-Peptides
  • Blood-Brain Barrier
  • Cerebrovascular Circulation
  • Endothelium, Vascular
  • Glucose Transporter Type 1

Identity

PubMed Central ID

  • PMC4731873

Scopus Document Identifier

  • 84925659468

Digital Object Identifier (DOI)

  • 10.1038/nn.3986

PubMed ID

  • 25811474

Additional Document Info

volume

  • 18

issue

  • 4