Iadecola, Costantino

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Association Between Soluble Intercellular Adhesion Molecule-1 and Intracerebral Hemorrhage Outcomes in the FAST Trial. Stroke. 2023 Academic Article GET IT
Calcium transients in nNOS neurons underlie distinct phases of the neurovascular response to barrel cortex activation in awake mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023 Academic Article GET IT
Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome. Journal of magnetic resonance imaging : JMRI. 2023 Review GET IT
Immune compartments at the brain's borders in health and neurovascular diseases. Seminars in immunopathology. 2023 Review GET IT
Times cited: 1
Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress. Research square. 2023 Article GET IT
Brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke. bioRxiv : the preprint server for biology. 2023 Article GET IT
The Neurovasculome: Key Roles in Brain Health and Cognitive Impairment: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke. 2023 Review GET IT
Times cited: 1
Long-term risk of seizure after posterior reversible encephalopathy syndrome. Annals of clinical and translational neurology. 2023 Academic Article GET IT
Times cited: 1
Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimerâ€™s disease. bioRxiv : the preprint server for biology. 2023 Article GET IT
Influenza-Like Illness as a Short-Term Risk Factor for Arterial Dissection. Stroke. 2023 Letter GET IT
Sexually Dimorphic Association of Circulating Plasminogen Activator Inhibitor-1 Levels and Body Mass Index with Cerebrospinal Fluid Biomarkers of Alzheimer's Pathology in Preclinical Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023 Academic Article GET IT
Times cited: 1
Association of liver fibrosis with cognitive test performance and brain imaging parameters in the UK Biobank study. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022 Academic Article GET IT
Times cited: 2
Hypertension, Neurovascular Dysfunction, and Cognitive Impairment. Hypertension (Dallas, Tex. : 1979). 2022 Review GET IT
Times cited: 6
Risk of Stroke After Posterior Reversible Encephalopathy Syndrome. Stroke. 2022 Academic Article GET IT
Times cited: 1
Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aβ production under hypoxia and cerebral hypoperfusion. Molecular psychiatry. 2022 Academic Article GET IT
Times cited: 4
Association between liver fibrosis and incident dementia in the UK Biobank study. European journal of neurology. 2022 Academic Article GET IT
Times cited: 5
Risk Stratification Models for Stroke in Patients Hospitalized with COVID-19 Infection. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2022 Academic Article GET IT
When the BBB goes MIA. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
Introduction to the Compendium on Stroke and Neurocognitive Impairment. Circulation research. 2022 Review GET IT
Impact of Cigarette Smoking and Its Interaction with Hypertension and Diabetes on Cognitive Function in Older Americans. Journal of Alzheimer's disease : JAD. 2022 Academic Article GET IT
Cerebral Microbleeds and Acute Hematoma Characteristics in the ATACH-2 and MISTIE III Trials. Neurology. 2021 Academic Article GET IT
Times cited: 3
Revisiting the neurovascular unit. Nature neuroscience. 2021 Review GET IT
Times cited: 132
Association Between Intracerebral Hemorrhage and Subsequent Arterial Ischemic Events in Participants From 4 Population-Based Cohort Studies. JAMA neurology. 2021 Academic Article GET IT
Times cited: 27
Mechanisms of Ischemic Stroke in Patients with Cancer: A Prospective Study. Annals of neurology. 2021 Academic Article GET IT
Times cited: 20
Stroke affects intestinal immune cell trafficking to the central nervous system. Brain, behavior, and immunity. 2021 Academic Article GET IT
Times cited: 19
Role of microglial and endothelial CD36 in post-ischemic inflammasome activation and interleukin-1β-induced endothelial activation. Brain, behavior, and immunity. 2021 Academic Article GET IT
Times cited: 9
Diffusion-Weighted Imaging Lesions After Intracerebral Hemorrhage and Risk of Stroke: A MISTIE III and ATACH-2 Analysis. Stroke. 2021 Academic Article GET IT
Times cited: 10
Endothelial S1P₁ Signaling Counteracts Infarct Expansion in Ischemic Stroke. Circulation research. 2020 Academic Article GET IT
Times cited: 50
A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage. JAMA neurology. 2020 Review GET IT
Times cited: 30
tPA Deficiency Underlies Neurovascular Coupling Dysfunction by Amyloid-β. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2020 Academic Article GET IT
Times cited: 16
Elevated post-ischemic ubiquitination results from suppression of deubiquitinase activity and not proteasome inhibition. Cellular and molecular life sciences : CMLS. 2020 Academic Article GET IT
Times cited: 5
Effects of COVID-19 on the Nervous System. Cell. 2020 Review GET IT
Times cited: 360
Machine Learning Prediction of Stroke Mechanism in Embolic Strokes of Undetermined Source. Stroke. 2020 Academic Article GET IT
Times cited: 23
Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration. Nature neuroscience. 2020 Academic Article GET IT
Times cited: 43
A Novel Neurovascular Liaison Governing the Blood-Brain Barrier. Neuron. 2020 Comment GET IT
Association between liver fibrosis and cognition in a nationally representative sample of older adults. European journal of neurology. 2020 Academic Article GET IT
Times cited: 12
Endothelium-Macrophage Crosstalk Mediates Blood-Brain Barrier Dysfunction in Hypertension. Hypertension (Dallas, Tex. : 1979). 2020 Academic Article GET IT
Times cited: 52
Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza. JAMA neurology. 2020 Academic Article GET IT
Times cited: 373
Immune responses to stroke: mechanisms, modulation, and therapeutic potential. The Journal of clinical investigation. 2020 Review GET IT
Times cited: 225
Revisiting atherosclerosis and dementia. Nature neuroscience. 2020 Comment GET IT
Times cited: 15
Framingham General Cardiovascular Risk Score and Cognitive Impairment: The Power of Foresight. Journal of the American College of Cardiology. 2020 Editorial Article GET IT
Times cited: 2
Risk of Ischemic Stroke in Patients with Covid-19 versus Patients with Influenza. medRxiv : the preprint server for health sciences. 2020 Article GET IT
Times cited: 4310
Blood Pressure Ups and Downs Foreshadow Cerebral Microangiopathy. Journal of the American College of Cardiology. 2020 Editorial Article GET IT
Times cited: 6
Distinct Commensal Bacterial Signature in the Gut Is Associated With Acute and Long-Term Protection From Ischemic Stroke. Stroke. 2020 Academic Article GET IT
Times cited: 48
Trends in Active Cigarette Smoking Among Stroke Survivors in the United States, 1999 to 2018. Stroke. 2020 Academic Article GET IT
Times cited: 13
Risk factor for Alzheimer's disease breaks the blood-brain barrier. Nature. 2020 Comment GET IT
Times cited: 25
Non-Traumatic Subdural Hemorrhage and Risk of Arterial Ischemic Events. Stroke. 2020 Academic Article GET IT
Times cited: 10
Prohibitin S-Nitrosylation Is Required for the Neuroprotective Effect of Nitric Oxide in Neuronal Cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2020 Academic Article GET IT
Times cited: 11
Alzheimer's Disease and Vascular Aging: JACC Focus Seminar. Journal of the American College of Cardiology. 2020 Review GET IT
Times cited: 126
Inflammation, Autoimmunity, Infection, and Stroke: Epidemiology and Lessons From Therapeutic Intervention. Stroke. 2020 Review GET IT
Times cited: 48
Publisher Correction: Dietary salt promotes cognitive impairment through tau phosphorylation. Nature. 2020 Academic Article GET IT
Liver Fibrosis Indices and Outcomes After Primary Intracerebral Hemorrhage. Stroke. 2020 Academic Article GET IT
Times cited: 34
Reclassification of Ischemic Stroke Etiological Subtypes on the Basis of High-Risk Nonstenosing Carotid Plaque. Stroke. 2019 Academic Article GET IT
Times cited: 34
Prohibitin levels regulate OMA1 activity and turnover in neurons. Cell death and differentiation. 2019 Academic Article GET IT
Times cited: 30
Risk of Arterial Ischemic Events After Intracerebral Hemorrhage. Stroke. 2019 Academic Article GET IT
Times cited: 36
Statins and Cognitive Impairment: Not a Culprit, Protective in Some?. Journal of the American College of Cardiology. 2019 Editorial Article GET IT
Times cited: 3
Th17 and Cognitive Impairment: Possible Mechanisms of Action. Frontiers in neuroanatomy. 2019 Review GET IT
Times cited: 52
Plasma Membrane Affiliated AMPA GluA1 in Estrogen Receptor β-containing Paraventricular Hypothalamic Neurons Increases Following Hypertension in a Mouse Model of Post-menopause. Neuroscience. 2019 Academic Article GET IT
Times cited: 8
Dietary salt promotes cognitive impairment through tau phosphorylation. Nature. 2019 Academic Article GET IT
Times cited: 109
Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto. International journal of stroke : official journal of the International Stroke Society. 2019 Academic Article GET IT
Times cited: 12
Amyloid-Beta Modulates Low-Threshold Activated Voltage-Gated L-Type Calcium Channels of Arcuate Neuropeptide Y Neurons Leading to Calcium Dysregulation and Hypothalamic Dysfunction. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2019 Academic Article GET IT
Times cited: 29
Cancer-Related Ischemic Stroke Has a Distinct Blood mRNA Expression Profile. Stroke. 2019 Academic Article GET IT
Times cited: 9
Plasma lipocalin-2 levels in the preclinical stage of Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands). 2019 Academic Article GET IT
Times cited: 23
Associations between cerebrovascular risk factors and parkinson disease. Annals of neurology. 2019 Academic Article GET IT
Times cited: 47
Association Between Unrecognized Myocardial Infarction and Cerebral Infarction on Magnetic Resonance Imaging. JAMA neurology. 2019 Academic Article GET IT
Times cited: 22
AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke. Cell reports. 2019 Academic Article GET IT
Times cited: 13
Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel. Journal of the American College of Cardiology. 2019 Review GET IT
Times cited: 272
Preventing dementia by preventing stroke: The Berlin Manifesto. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019 Review GET IT
Times cited: 159
Tailoring the Approach to Embolic Stroke of Undetermined Source: A Review. JAMA neurology. 2019 Review GET IT
Times cited: 77
The risk of arterial thromboembolic events after cancer diagnosis. Research and practice in thrombosis and haemostasis. 2019 Academic Article GET IT
Times cited: 10
Animal Models of Hypertension: A Scientific Statement From the American Heart Association. Hypertension (Dallas, Tex. : 1979). 2019 Review GET IT
Times cited: 153
Neurovascular and Cognitive Dysfunction in Hypertension. Circulation research. 2019 Review GET IT
Times cited: 227
Association Between Heart Transplantation and Subsequent Risk of Stroke Among Patients With Heart Failure. Stroke. 2019 Academic Article GET IT
Times cited: 12
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models. Nature neuroscience. 2019 Academic Article GET IT
Times cited: 208
Short-Term Risk of Ischemic Stroke After Detection of Left Ventricular Thrombus on Cardiac Magnetic Resonance Imaging. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2019 Academic Article GET IT
Times cited: 7
Retinol Binding Protein 4 Levels Are Not Altered in Preclinical Alzheimer's Disease and Not Associated with Cognitive Decline or Incident Dementia. Journal of Alzheimer's disease : JAD. 2019 Academic Article GET IT
Times cited: 7
Vascular dysfunction-The disregarded partner of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019 Academic Article GET IT
Times cited: 354
Arterial thromboembolic events preceding the diagnosis of cancer in older persons. Blood. 2018 Academic Article GET IT
Times cited: 109
Duration of Heightened Ischemic Stroke Risk After Acute Myocardial Infarction. Journal of the American Heart Association. 2018 Academic Article GET IT
Times cited: 22
Ablation of nasal-associated lymphoid tissue does not affect focal ischemic brain injury in mice. PloS one. 2018 Academic Article GET IT
Times cited: 5
Hypertension, dietary salt and cognitive impairment. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018 Review GET IT
Times cited: 50
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function. Nature communications. 2018 Academic Article GET IT
Times cited: 77
Cerebrovascular Alterations in Alzheimer Disease. Circulation research. 2018 Review GET IT
Times cited: 61
Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress. Journal of neurochemistry. 2018 Academic Article GET IT
Times cited: 24
Endogenous Protection from Ischemic Brain Injury by Preconditioned Monocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2018 Academic Article GET IT
Times cited: 45
New diagnosis of cancer and the risk of subsequent cerebrovascular events. Neurology. 2018 Academic Article GET IT
Times cited: 28
Ischemic stroke in cancer patients: A review of an underappreciated pathology. Annals of neurology. 2018 Review GET IT
Times cited: 127
Publisher Correction: Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases. Scientific reports. 2018 Article GET IT
Times cited: 2
Population-Based Assessment of the Long-Term Risk of Seizures in Survivors of Stroke. Stroke. 2018 Academic Article GET IT
Times cited: 30
Critical Role of Flavin and Glutathione in Complex I-Mediated Bioenergetic Failure in Brain Ischemia/Reperfusion Injury. Stroke. 2018 Academic Article GET IT
Times cited: 57
Estrogen receptor beta modulates permeability transition in brain mitochondria. Biochimica et biophysica acta. Bioenergetics. 2018 Academic Article GET IT
Times cited: 28
Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases. Scientific reports. 2018 Academic Article GET IT
Times cited: 52
Reply: Arterial Thromboembolism in Non-Hodgkin Lymphoma, as the Presentation of Occult Cancer, and With Cancer Therapies. Journal of the American College of Cardiology. 2018 Letter GET IT
Times cited: 4
Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response. Nature neuroscience. 2018 Academic Article GET IT
Times cited: 188
Richard Joel Traystman, PhD. Stroke. 2017 Academic Article GET IT
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease. Neuron. 2017 Review GET IT
Times cited: 1066
Association Between Troponin Levels and Embolic Stroke of Undetermined Source. Journal of the American Heart Association. 2017 Academic Article GET IT
Times cited: 27
Safety Outcomes After Percutaneous Transcatheter Closure of Patent Foramen Ovale. Stroke. 2017 Academic Article GET IT
Times cited: 43
Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association. Stroke. 2017 Review GET IT
Times cited: 210
Risk of Arterial Thromboembolism in Patients With Cancer. Journal of the American College of Cardiology. 2017 Academic Article GET IT
Times cited: 366
Rollercoaster Blood Pressure: An Alzheimer Disease Risk Factor?. Circulation. 2017 Editorial Article GET IT
Times cited: 3
Brain perivascular macrophages: characterization and functional roles in health and disease. Journal of molecular medicine (Berlin, Germany). 2017 Review GET IT
Times cited: 111
Translational Stroke Research: Vision and Opportunities. Stroke. 2017 Review GET IT
Times cited: 83
Association between Intracranial Atherosclerotic Calcium Burden and Angiographic Luminal Stenosis Measurements. AJNR. American journal of neuroradiology. 2017 Academic Article GET IT
Times cited: 11
Neuronal expression of the mitochondrial protein prohibitin confers profound neuroprotection in a mouse model of focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2017 Academic Article GET IT
Times cited: 12
Neutrophil-Lymphocyte Ratio and Perihematomal Edema Growth in Intracerebral Hemorrhage. Stroke. 2017 Academic Article GET IT
Times cited: 48
Rates of Spinal Cord Infarction After Repair of Aortic Aneurysm or Dissection. Stroke. 2017 Academic Article GET IT
Times cited: 24
Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides. Circulation research. 2017 Academic Article GET IT
Times cited: 114
Outcomes after intracerebral hemorrhage from arteriovenous malformations. Neurology. 2017 Academic Article GET IT
Times cited: 44
Restarting Anticoagulant Therapy After Intracranial Hemorrhage: A Systematic Review and Meta-Analysis. Stroke. 2017 Review GET IT
Times cited: 143
Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 128
Introduction to the Stroke Compendium. Circulation research. 2017 Editorial Article GET IT
Times cited: 7
New generations of dihydropyridines for treatment of hypertension. Journal of geriatric cardiology : JGC. 2017 Review GET IT
Times cited: 40
Recent progress in translational research on neurovascular and neurodegenerative disorders. Restorative neurology and neuroscience. 2017 Review GET IT
Times cited: 15
Cryptogenic Stroke and Nonstenosing Intracranial Calcified Atherosclerosis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2016 Academic Article GET IT
Times cited: 20
Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension. The Journal of clinical investigation. 2016 Academic Article GET IT
Times cited: 186
Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain. Journal of neuroinflammation. 2016 Academic Article GET IT
Times cited: 65
Untangling Neurons With Endothelial Nitric Oxide. Circulation research. 2016 Editorial Article GET IT
Times cited: 11
Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association. Hypertension (Dallas, Tex. : 1979). 2016 Review GET IT
Times cited: 416
Inflammation and Stroke: An Overview. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2016 Review GET IT
Times cited: 518
Nosocomial Infections and Outcomes after Intracerebral Hemorrhage: A Population-Based Study. Neurocritical care. 2016 Academic Article GET IT
Times cited: 36
Intracerebral Hemorrhage Outcomes in Patients with Systemic Cancer. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2016 Academic Article GET IT
Times cited: 17
Gadolinium Enhancement in Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta-Analysis. Journal of the American Heart Association. 2016 Review GET IT
Times cited: 67
Rate of perihaematomal oedema expansion is associated with poor clinical outcomes in intracerebral haemorrhage. Journal of neurology, neurosurgery, and psychiatry. 2016 Academic Article GET IT
Times cited: 41
Redistribution of NMDA Receptors in Estrogen-Receptor-β-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure. Neuroendocrinology. 2016 Academic Article GET IT
Times cited: 20
OC-02 - Risk of arterial thromboembolism in patients with breast cancer. Thrombosis research. 2016 Academic Article GET IT
Risk of Intracerebral Hemorrhage after Emergency Department Discharges for Hypertension. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2016 Academic Article GET IT
Times cited: 6
Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells. Nature medicine. 2016 Academic Article GET IT
Times cited: 621
Structural connectome disruption at baseline predicts 6-months post-stroke outcome. Human brain mapping. 2016 Academic Article GET IT
Times cited: 53
Vascular and Metabolic Factors in Alzheimer's Disease and Related Dementias: Introduction. Cellular and molecular neurobiology. 2016 Editorial Article GET IT
Times cited: 38
Association Between Nonstenosing Carotid Artery Plaque on MR Angiography and Acute Ischemic Stroke. JACC. Cardiovascular imaging. 2016 Letter GET IT
Times cited: 39
Atrial Fibrillation and Mechanisms of Stroke: Time for a New Model. Stroke. 2016 Review GET IT
Times cited: 374
Consensus statement for diagnosis of subcortical small vessel disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Review GET IT
Times cited: 135
Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Academic Article GET IT
Times cited: 106
Alterations in the subcellular distribution of NADPH oxidase p47(phox) in hypothalamic paraventricular neurons following slow-pressor angiotensin II hypertension in female mice with accelerated ovarian failure. The Journal of comparative neurology. 2015 Academic Article GET IT
Times cited: 11
Adipocyte-derived factors in age-related dementia and their contribution to vascular and Alzheimer pathology. Biochimica et biophysica acta. 2015 Review GET IT
Times cited: 126
Endothelial CD36 Contributes to Postischemic Brain Injury by Promoting Neutrophil Activation via CSF3. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Academic Article GET IT
Times cited: 40
The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Nucleic acids research. 2015 Academic Article GET IT
Times cited: 20
Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology. Cell metabolism. 2015 Review GET IT
Times cited: 126
Sex differences in NMDA GluN1 plasticity in rostral ventrolateral medulla neurons containing corticotropin-releasing factor type 1 receptor following slow-pressor angiotensin II hypertension. Neuroscience. 2015 Academic Article GET IT
Times cited: 21
NMDA Receptor Plasticity in the Hypothalamic Paraventricular Nucleus Contributes to the Elevated Blood Pressure Produced by Angiotensin II. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Academic Article GET IT
Times cited: 39
Impaired Aβ clearance: a potential link between atherosclerosis and Alzheimer's disease. Frontiers in aging neuroscience. 2015 Review GET IT
Times cited: 58
Magnetic resonance angiography detection of abnormal carotid artery plaque in patients with cryptogenic stroke. Journal of the American Heart Association. 2015 Academic Article GET IT
Times cited: 74
Diagnostic yield of echocardiography in cancer patients with ischemic stroke. Journal of neuro-oncology. 2015 Academic Article GET IT
Times cited: 21
Sugar and Alzheimer's disease: a bittersweet truth. Nature neuroscience. 2015 Comment GET IT
Times cited: 19
Female protection from slow-pressor effects of angiotensin II involves prevention of ROS production independent of NMDA receptor trafficking in hypothalamic neurons expressing angiotensin 1A receptors. Synapse (New York, N.Y.). 2015 Academic Article GET IT
Times cited: 28
Detection of Symptomatic Carotid Plaque Using Source Data from MR and CT Angiography: A Correlative Study. Cerebrovascular diseases (Basel, Switzerland). 2015 Academic Article GET IT
Times cited: 29
Exploring the brain's structural connectome: A quantitative stroke lesion-dysfunction mapping study. Human brain mapping. 2015 Academic Article GET IT
Times cited: 32
Dangerous leaks: blood-brain barrier woes in the aging hippocampus. Neuron. 2015 Comment GET IT
Times cited: 37
The role of microglia and myeloid immune cells in acute cerebral ischemia. Frontiers in cellular neuroscience. 2015 Review GET IT
Times cited: 190
Neurovascular regulation in the ischemic brain. Antioxidants & redox signaling. 2015 Academic Article GET IT
Times cited: 65
Association between incident cancer and subsequent stroke. Annals of neurology. 2015 Academic Article GET IT
Times cited: 147
SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2014 Academic Article GET IT
Times cited: 24
The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction. Nature communications. 2014 Academic Article GET IT
Times cited: 87
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. 2014 GET IT
Times cited: 1052
Slow-pressor angiotensin II hypertension and concomitant dendritic NMDA receptor trafficking in estrogen receptor β-containing neurons of the mouse hypothalamic paraventricular nucleus are sex and age dependent. The Journal of comparative neurology. 2014 Academic Article GET IT
Times cited: 34
Commentary on Myers et al.: growing role of the innate immunity receptor CD36 in central nervous system diseases. Experimental neurology. 2014 Academic Article GET IT
Times cited: 14
Perioperative atrial fibrillation and the long-term risk of ischemic stroke. JAMA. 2014 Academic Article GET IT
Times cited: 234
Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice. Journal of immunology (Baltimore, Md. : 1950). 2014 Academic Article GET IT
Times cited: 97
Cryptogenic subtype predicts reduced survival among cancer patients with ischemic stroke. Stroke. 2014 Academic Article GET IT
Times cited: 67
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 Academic Article GET IT
Times cited: 64
Recurrent thromboembolic events after ischemic stroke in patients with cancer. Neurology. 2014 Academic Article GET IT
Times cited: 111
Age-dependent neurovascular dysfunction and damage in a mouse model of cerebral amyloid angiopathy. Stroke. 2014 Academic Article GET IT
Times cited: 80
Hypertension and dementia. Hypertension (Dallas, Tex. : 1979). 2014 Academic Article GET IT
Times cited: 5
Dichotomous effects of chronic intermittent hypoxia on focal cerebral ischemic injury. Stroke. 2014 Academic Article GET IT
Times cited: 35
Amyloid β-Related Central Nervous System Angiitis Presenting With an Isolated Seizure. The Neurohospitalist. 2014 Academic Article GET IT
Times cited: 7
Prohibitin viral gene transfer protects hippocampal CA1 neurons from ischemia and ameliorates postischemic hippocampal dysfunction. Stroke. 2014 Academic Article GET IT
Times cited: 28
Angiophagy: clearing or clogging microvessels?. Science translational medicine. 2014 Comment GET IT
Immune mechanisms in cerebral ischemic tolerance. Frontiers in neuroscience. 2014 Review GET IT
Times cited: 33
Mir-592 regulates the induction and cell death-promoting activity of p75NTR in neuronal ischemic injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 Academic Article GET IT
Times cited: 75
Predicting future brain tissue loss from white matter connectivity disruption in ischemic stroke. Stroke. 2014 Academic Article GET IT
Times cited: 37
Water deprivation induces neurovascular and cognitive dysfunction through vasopressin-induced oxidative stress. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2014 Academic Article GET IT
Times cited: 44
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2013 Academic Article GET IT
Times cited: 71
The pathobiology of vascular dementia. Neuron. 2013 Review GET IT
Times cited: 1122
COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ. American journal of physiology. Heart and circulatory physiology. 2013 Academic Article GET IT
Times cited: 29
Hypertension: a harbinger of stroke and dementia. Hypertension (Dallas, Tex. : 1979). 2013 Review GET IT
Times cited: 252
Circulating endothelin-1 alters critical mechanisms regulating cerebral microcirculation. Hypertension (Dallas, Tex. : 1979). 2013 Academic Article GET IT
Times cited: 47
Lipoprotein receptor-related protein-6 protects the brain from ischemic injury. Stroke. 2013 Academic Article GET IT
Times cited: 19
The microcircualtion--fantastic voyage: introduction. Stroke. 2013 Article GET IT
Times cited: 2
Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2013 Academic Article GET IT
Times cited: 28
Paroxysmal supraventricular tachycardia and the risk of ischemic stroke. Stroke. 2013 Academic Article GET IT
Times cited: 80
A concerted appeal for international cooperation in preclinical stroke research. Stroke. 2013 Academic Article GET IT
Times cited: 90
Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons. American journal of physiology. Regulatory, integrative and comparative physiology. 2013 Academic Article GET IT
Times cited: 49
Membrane trafficking of NADPH oxidase p47(phox) in paraventricular hypothalamic neurons parallels local free radical production in angiotensin II slow-pressor hypertension. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2013 Academic Article GET IT
Times cited: 36
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 97
Genetic deletion of CD36 enhances injury after acute neonatal stroke. Annals of neurology. 2012 Academic Article GET IT
Times cited: 66
Brain and circulating levels of Aβ1-40 differentially contribute to vasomotor dysfunction in the mouse brain. Stroke. 2012 Academic Article GET IT
Times cited: 45
ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension. The Journal of clinical investigation. 2012 Academic Article GET IT
Times cited: 124
Distribution of angiotensin type 1a receptor-containing cells in the brains of bacterial artificial chromosome transgenic mice. Neuroscience. 2012 Academic Article GET IT
Times cited: 49
Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion. Stroke. 2012 Academic Article GET IT
Times cited: 44
Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia. Hypertension (Dallas, Tex. : 1979). 2012 Academic Article GET IT
Times cited: 56
Association between major perioperative hemorrhage and stroke or Q-wave myocardial infarction. Circulation. 2012 Academic Article GET IT
Times cited: 61
Peroxiredoxin sets the brain on fire after stroke. Nature medicine. 2012 Article GET IT
Times cited: 34
Brain-immune interactions and ischemic stroke: clinical implications. Archives of neurology. 2012 Review GET IT
Times cited: 159
Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Academic Article GET IT
Times cited: 80
Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons. American journal of physiology. Regulatory, integrative and comparative physiology. 2012 Academic Article GET IT
Times cited: 22
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain. Hypertension (Dallas, Tex. : 1979). 2012 Academic Article GET IT
Times cited: 47
The link between angiotensin II-mediated anxiety and mood disorders with NADPH oxidase-induced oxidative stress. International journal of physiology, pathophysiology and pharmacology. 2012 Academic Article GET IT
Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation. Cellular and molecular life sciences : CMLS. 2012 Academic Article GET IT
Times cited: 22
Prohibitin reduces mitochondrial free radical production and protects brain cells from different injury modalities. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Academic Article GET IT
Times cited: 73
Stroke research at a crossroad: asking the brain for directions. Nature neuroscience. 2011 Academic Article GET IT
Times cited: 309
Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury. PloS one. 2011 Academic Article GET IT
Times cited: 27
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke. 2011 Review GET IT
Times cited: 2590
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Plasma epinephrine modulates the cerebrovasodilation evoked by electrical stimulation of dorsal medulla. Brain research. 1990 Academic Article GET IT
Times cited: 8
Local and remote microvascular changes in excitotoxin-induced focal brain lesions. Brain research. 1989 Academic Article GET IT
Times cited: 5
Global reduction in cerebral blood flow and metabolism elicited from intrinsic neurons of fastigial nucleus. Brain research. 1989 Academic Article GET IT
Times cited: 29
Facts and trends in cerebral blood flow and metabolism: synopsis of brain '89. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1989 Academic Article GET IT
Times cited: 6
Neuronal and endothelial sites of acetylcholine synthesis and release associated with microvessels in rat cerebral cortex: ultrastructural and neurochemical studies. Brain research. 1988 Academic Article GET IT
Times cited: 74
Role of adrenal catecholamines in cerebrovasodilation evoked from brain stem. The American journal of physiology. 1987 Academic Article GET IT
Times cited: 8
Role of local neurons in cerebrocortical vasodilation elicited from cerebellum. The American journal of physiology. 1987 Academic Article GET IT
Times cited: 51
Local cholinergic mechanisms participate in the increase in cortical cerebral blood flow elicited by electrical stimulation of the fastigial nucleus in rat. Brain research. 1987 Academic Article GET IT
Times cited: 39
Lesions of nucleus tractus solitarii globally impair cerebrovascular autoregulation. The American journal of physiology. 1986 Academic Article GET IT
Times cited: 46
A novel vasodepressor response elicited from the rat cerebellar fastigial nucleus: the fastigial depressor response. Brain research. 1986 Academic Article GET IT
Times cited: 56
Muscarinic cholinergic receptors mediate the cerebrovasodilation elicited by stimulation of the cerebellar fastigial nucleus in rat. Brain research. 1986 Academic Article GET IT
Times cited: 26
Adrenal catecholamines participate in the cerebrovascular vasodilation elicited by electrical stimulation of the dorsal medullary reticular formation in rat. Acta physiologica Scandinavica. Supplementum. 1986 Academic Article GET IT
Times cited: 4
Local cholinergic mechanisms mediate the cortical vasodilation elicited by electrical stimulation of the fastigial nucleus. Acta physiologica Scandinavica. Supplementum. 1986 Academic Article GET IT
Times cited: 3
Widespread reductions in cerebral blood flow and metabolism elicited by electrical stimulation of the parabrachial nucleus in rat. Brain research. 1985 Academic Article GET IT
Times cited: 48
Evidence that disruption of the blood-brain barrier precedes reduction in cerebral blood flow in hypertensive encephalopathy. Hypertension (Dallas, Tex. : 1979). 1984 Academic Article GET IT
Times cited: 85
Lesions of the basal forebrain in rat selectively impair the cortical vasodilation elicited from cerebellar fastigial nucleus. Brain research. 1983 Academic Article GET IT
Times cited: 52
Global cerebral vasodilatation elicited by focal electrical stimulation within the dorsal medullary reticular formation in anesthetized rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1983 Academic Article GET IT
Times cited: 22
Local cerebral blood flow increases during auditory and emotional processing in the conscious rat. Science (New York, N.Y.). 1983 Academic Article GET IT
Times cited: 97
Global increase in cerebral metabolism and blood flow produced by focal electrical stimulation of dorsal medullary reticular formation in rat. Brain research. 1983 Academic Article GET IT
Times cited: 57
Electrical stimulation of cerebellar fastigial nucleus increases cerebral cortical blood flow without change in local metabolism: evidence for an intrinsic system in brain for primary vasodilation. Brain research. 1983 Academic Article GET IT
Times cited: 109
Italian study of cerebral reversible ischemic attacks. II. The hematocrit and hemoglobin distribution and its relationship between clinical pattern and angiographic abnormalities. European neurology. 1983 Academic Article GET IT
Times cited: 1
[Hemorrheological changes in cerebrovascular disease]. La Ricerca in clinica e in laboratorio. 1983 Academic Article GET IT
Times cited: 1
Global cerebral vasodilation by stimulation of rat fastigial cerebellar nucleus. The American journal of physiology. 1982 Academic Article GET IT
Times cited: 93
Ischaemic intermittent claudication of the masticatory muscles: two case reports. 1980 GET IT
Times cited: 3

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Co-investigator Network

Funding awarded

Alzheimer Pathology and Neurovascular Dysfunction awarded by National Institute of Neurological Disorders & Stroke Principal Investigator 2023 - 2027
ApoE4, neurovascular injury and cognitive impairment awarded by National Institute of Neurological Disorders & Stroke Principal Investigator 2022 - 2027
Dietary sodium, neurovascular dysfunction and cerebrovascular risk awarded by National Institute of Neurological Disorders & Stroke Principal Investigator 2021 - 2026
Addgene 696261 awarded by Addgene, Inc. Principal Investigator 2022 - 2023

tPA and cerebrovascular regulation in a model of ß-amyloid pathology awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2023 - 2028
Role of prohibitin nitrosylation in its neuroprotective functions awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2022 - 2027
MRI Detection of CarotId Plaques as a mecHanism for Embolic strokes of undeteRmined source (MRI DECIPHER) awarded by National Heart, Lung, & Blood Institute Co-Investigator 2019 - 2024
Role of CaMKII-alpha ubiquitination in ischemic stroke awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2018 - 2024

Gut Immunity, Neurovascular dysregulation and Cognitive Impairment awarded by National Institute of Neurological Disorders & Stroke Key Personnel 2022 - 2027
Role of perivascular macrophages in ApoE4-induced neurovascular dysfunction awarded by BrightFocus Foundation Key Personnel 2022 - 2024
:Role of perivascular macrophages in ApoE4-induced neurovascular dysfunction awarded by American Heart Association Key Personnel 2022 - 2023
Neuroimmune Mechanisms of Cognitive Impairment in Salt-sensitive Hypertension awarded by National Institute of Neurological Disorders & Stroke Key Personnel 2021 - 2023
Hypothalamic Cytokines, Glutamate Receptor Plasticity, and Blood Pressure awarded by National Heart, Lung, & Blood Institute Key Personnel 2017 - 2023

High-speed imaging of cortical and white matter microvascular flow in ADRD models awarded by National Institute of General Medical Sciences Principal Investigator Subaward 2022 - 2025

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Background

education and training

M.D., University of Rome Faculty of Medicine and Surgery (Italy) 1977

Contact

full name

Costantino Iadecola

primary email

coi2001@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Costantino Iadecola Director of the Feil Family Brain and Mind Research Institute

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage