Somatic Genome Editing Goes Viral. Academic Article uri icon

Overview

abstract

  • Generating new mouse models of cancer is a challenging and laborious task that can require years of investment to interrogate a single gene. Now, Jonkers and colleagues describe the first application of CRISPR-based genome editing in the mammary gland, providing a new approach to dissect complex genetic interactions in vivo.

publication date

  • August 20, 2016

Research

keywords

  • CRISPR-Cas Systems
  • Gene Editing

Identity

PubMed Central ID

  • PMC5048560

Scopus Document Identifier

  • 84994860414

Digital Object Identifier (DOI)

  • 10.1016/j.molmed.2016.08.004

PubMed ID

  • 27555346

Additional Document Info

volume

  • 22

issue

  • 10