Emerging links between m6A and misregulated mRNA methylation in cancer. Academic Article uri icon

Overview

abstract

  • N 6-methyladenosine (m6A) in mRNA has emerged as a crucial epitranscriptomic modification that controls cellular differentiation and pluripotency. Recent studies are pointing to a role for the RNA methylation program in cancer self-renewal and cell fate, making this a new and promising therapeutic avenue for investigation.

publication date

  • January 12, 2017

Research

keywords

  • Adenosine
  • Neoplasms
  • RNA Processing, Post-Transcriptional
  • RNA, Messenger

Identity

PubMed Central ID

  • PMC5228104

Scopus Document Identifier

  • 85009285174

Digital Object Identifier (DOI)

  • 10.1073/pnas.101001498

PubMed ID

  • 28081722

Additional Document Info

volume

  • 9

issue

  • 1