Genetic Manipulation with Viral Vectors to Assess Metabolism and Adipose Tissue Function. Academic Article uri icon

Overview

abstract

  • Viral vectors have become widely used tools for genetic manipulation of adipose tissues to understand the biology and function of adipocytes in metabolism. There are a number of different viral vectors commonly used: retrovirus, lentivirus, adenovirus, and adeno-associated virus (AAV). Here, we review examples from the literature and describe methods to transduce adipocytes and adipose tissues using retrovirus, lentivirus, adenovirus, and AAV to ascertain gene function in adipose biology.

publication date

  • January 1, 2017

Research

keywords

  • Adipose Tissue
  • Energy Metabolism
  • Genetic Vectors
  • Transduction, Genetic
  • Viruses

Identity

Scopus Document Identifier

  • 85014110054

Digital Object Identifier (DOI)

  • 10.1007/978-1-4939-6820-6_11

PubMed ID

  • 28244045

Additional Document Info

volume

  • 1566