TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease. Academic Article uri icon

Overview

abstract

  • Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.

publication date

  • September 6, 2017

Research

keywords

  • Awards and Prizes
  • Cells
  • Physiology
  • Signal Transduction
  • TOR Serine-Threonine Kinases

Identity

Scopus Document Identifier

  • 85028879625

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2017.08.019

PubMed ID

  • 28888322

Additional Document Info

volume

  • 171

issue

  • 1