Intracellular Ca2+ requirements for zymosan-stimulated phosphoinositide hydrolysis in mouse peritoneal macrophages. Academic Article uri icon

Overview

abstract

  • The phosphatidylinositol cycle has been demonstrated to be involved in the control of Ca2+ cytosolic levels in several cellular types. The Ca2+ requirements of phospholipase C activity and the described stimulation of phosphoinositide hydrolysis by Ca2+ ionophores make unclear the relationship between phosphatidylinositol cycle and Ca2+ mobilization. The results reported here suggest that intracellular Ca2+ is necessary for zymosan-stimulated phospholipase C activation in macrophages.

publication date

  • January 14, 1986

Research

keywords

  • Calcium
  • Macrophages
  • Phosphatidylinositols
  • Zymosan

Identity

Scopus Document Identifier

  • 0022560569

Digital Object Identifier (DOI)

  • 10.1016/0006-291x(86)90572-3

PubMed ID

  • 3004439

Additional Document Info

volume

  • 134

issue

  • 1