Engineered bacteria recycle tumor metabolic waste to boost immunotherapy. Academic Article uri icon

Overview

abstract

  • A recent study published in Nature by Canale et al. (2021) shows that engineered probiotic bacteria can be used to augment the availability of nutrients required for optimal immune cell function in tumors. This approach enhances anti-tumor immunity and improves the efficacy of immunotherapy in mouse models of cancer.

publication date

  • December 8, 2021

Research

keywords

  • Bacteria
  • Immunization, Secondary
  • Immunotherapy
  • Metabolic Engineering
  • Neoplasms

Identity

Scopus Document Identifier

  • 85122498776

Digital Object Identifier (DOI)

  • 10.1016/j.chom.2021.11.008

PubMed ID

  • 34883059

Additional Document Info

volume

  • 29

issue

  • 12