A ciliary synapse for "short-circuit" neuromodulation. uri icon

Overview

abstract

  • Nearly all neurons contain a primary cilium, but little is known about how this compartment contributes to neuromodulatory signaling. In a new study, Sheu et al. use cutting-edge electron microscopy and fluorescence imaging techniques to reveal a new type of synapse that enables chemical transmission between serotonergic axons and the primary cilia of hippocampal neurons.

publication date

  • September 1, 2022

Research

keywords

  • Cilia
  • Neurons
  • Synapses

Identity

Scopus Document Identifier

  • 85136590546

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2022.08.006

PubMed ID

  • 36055196

Additional Document Info

volume

  • 185

issue

  • 18