Cohen, David

Publications

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selected publications

Effect of Statin Use on Cancer-related Mortality in Nonalcoholic Fatty Liver Disease: A Prospective United States Cohort Study. Journal of clinical gastroenterology. 2022 Academic Article GET IT
Times cited: 9
The 2020 Nobel Prize for Medicine or Physiology for the Discovery of Hepatitis C Virus: A Triumph of Curiosity and Persistence. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
Times cited: 1
Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice. Nature communications. 2021 Academic Article GET IT
Times cited: 1
Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice. The Journal of biological chemistry. 2021 Academic Article GET IT
Times cited: 4
A human liver chimeric mouse model for non-alcoholic fatty liver disease. JHEP reports : innovation in hepatology. 2021 Academic Article GET IT
Times cited: 13
From NAFLD to MAFLD: Implications of a Premature Change in Terminology. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
Times cited: 192
Five-Year Outcomes of Endoscopic Sleeve Gastroplasty for the Treatment of Obesity. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2020 Academic Article GET IT
Times cited: 40
Development and external validation of a prediction risk model for short-term mortality among hospitalized U.S. COVID-19 patients: A proposal for the COVID-AID risk tool. PloS one. 2020 Academic Article GET IT
Times cited: 27
Improvement in insulin resistance and estimated hepatic steatosis and fibrosis after endoscopic sleeve gastroplasty. Gastrointestinal endoscopy. 2020 Academic Article GET IT
Times cited: 31
Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine. Proceedings of the National Academy of Sciences of the United States of America. 2020 Academic Article GET IT
Times cited: 8
Association between liver fibrosis and cognition in a nationally representative sample of older adults. European journal of neurology. 2020 Academic Article GET IT
Times cited: 12
Maternal Programming of Social Dominance via Milk Cytokines. iScience. 2020 Academic Article GET IT
Times cited: 5
Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
Times cited: 293
Gastrointestinal and Hepatic Manifestations of 2019 Novel Coronavirus Disease in a Large Cohort of Infected Patients From New York: Clinical Implications. Gastroenterology. 2020 Academic Article GET IT
Times cited: 95
SARS-COV-2 infection (coronavirus disease 2019) for the gastrointestinal consultant. World journal of gastroenterology. 2020 Review GET IT
Times cited: 40
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice. Scientific reports. 2020 Academic Article GET IT
Times cited: 15
Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice. Cell metabolism. 2020 Academic Article GET IT
Times cited: 35
Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. Cell metabolism. 2019 Academic Article GET IT
Times cited: 106
CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients. Liver international : official journal of the International Association for the Study of the Liver. 2019 Academic Article GET IT
Times cited: 95
Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Academic Article GET IT
Times cited: 7
Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity. JCI insight. 2019 Academic Article GET IT
Times cited: 16
Clinically relevant contact allergens in the modern era. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2019 Academic Article GET IT
Times cited: 2
Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
Times cited: 19
Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. 2019 Academic Article GET IT
Times cited: 56
Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1-induced steatosis. The Journal of biological chemistry. 2018 Academic Article GET IT
Times cited: 5
Trimming the Fat: Acetyl-CoA Carboxylase Inhibition for the Management of NAFLD. Hepatology (Baltimore, Md.). 2018 Editorial Article GET IT
Times cited: 19
Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction. Hepatology (Baltimore, Md.). 2018 Academic Article GET IT
Times cited: 23
CalR: A Web-Based Analysis Tool for Indirect Calorimetry Experiments. Cell metabolism. 2018 Academic Article GET IT
Times cited: 135
Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice. Cell host & microbe. 2018 Academic Article GET IT
Times cited: 66
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. The Journal of clinical investigation. 2018 Academic Article GET IT
Times cited: 19
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis. Nature medicine. 2018 Academic Article GET IT
Times cited: 89
Triglyceride Metabolism in the Liver. Comprehensive Physiology. 2017 Review GET IT
Times cited: 500
Regulation of fatty acid trafficking in liver by thioesterase superfamily member 1. Journal of lipid research. 2017 Academic Article GET IT
Times cited: 4
Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 25
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 181
Attenuated Effects of Bile Acids on Glucose Metabolism and Insulin Sensitivity in a Male Mouse Model of Prenatal Undernutrition. Endocrinology. 2017 Academic Article GET IT
Times cited: 17
Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue. Molecular metabolism. 2017 Academic Article GET IT
Times cited: 40
Phosphatidylcholine transfer protein/StarD2 promotes microvesicular steatosis and liver injury in murine experimental steatohepatitis. American journal of physiology. Gastrointestinal and liver physiology. 2017 Academic Article GET IT
Times cited: 11
Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism. Trends in endocrinology and metabolism: TEM. 2017 Review GET IT
Times cited: 77
Of TICE in Men. Cell metabolism. 2016 Comment GET IT
Times cited: 3
Genetic ablation of phosphatidylcholine transfer protein/StarD2 in ob/ob mice improves glucose tolerance without increasing energy expenditure. Metabolism: clinical and experimental. 2016 Academic Article GET IT
Times cited: 6
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature cell biology. 2016 Academic Article GET IT
Times cited: 132
Low testosterone in non-responsive coeliac disease: A case series, case-control study with comparisons to the National Health and Nutrition Examination Survey. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 2016 Academic Article GET IT
Times cited: 2
Not all mice are the same: Standardization of animal research data presentation. Hepatology (Baltimore, Md.). 2016 Academic Article GET IT
Times cited: 11
Not All Mice Are the Same: Standardization of Animal Research Data Presentation. Cellular and molecular gastroenterology and hepatology. 2016 Editorial Article GET IT
Times cited: 6
Understanding the Epidermal Barrier in Healthy and Compromised Skin: Clinically Relevant Information for the Dermatology Practitioner: Proceedings of an Expert Panel Roundtable Meeting. The Journal of clinical and aesthetic dermatology. 2016 Review GET IT
Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue. Molecular metabolism. 2016 Academic Article GET IT
Times cited: 29
Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease. Digestive diseases and sciences. 2016 Review GET IT
Times cited: 389
Lipids and bariatric procedures Part 2 of 2: scientific statement from the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and Obesity Medicine Association (OMA). 2016 GET IT
Times cited: 32
Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: EXECUTIVE SUMMARY. Journal of clinical lipidology. 2015 Academic Article GET IT
Times cited: 18
Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: FULL REPORT. Journal of clinical lipidology. 2015 Academic Article GET IT
Times cited: 18
Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis. Nature medicine. 2015 Academic Article GET IT
Times cited: 185
Targeted disruption of fibrinogen like protein-1 accelerates hepatocellular carcinoma development. Biochemical and biophysical research communications. 2015 Academic Article GET IT
Times cited: 28
Food-associated stimuli enhance barrier properties of gastrointestinal mucus. Biomaterials. 2015 Academic Article GET IT
Times cited: 41
Liver histology during Mipomersen therapy for severe hypercholesterolemia. Journal of clinical lipidology. 2014 Academic Article GET IT
Times cited: 38
CXCR3 controls T-cell accumulation in fat inflammation. Arteriosclerosis, thrombosis, and vascular biology. 2014 Academic Article GET IT
Times cited: 26
Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization. Molecular and cellular biology. 2014 Academic Article GET IT
Times cited: 23
Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway. The Journal of clinical investigation. 2014 Academic Article GET IT
Times cited: 26
An assessment by the Statin Liver Safety Task Force: 2014 update. 2014 GET IT
Times cited: 169
Lipids and the liver. Seminars in liver disease. 2013 Article GET IT
Times cited: 1
Lipoprotein metabolism, dyslipidemia, and nonalcoholic fatty liver disease. Seminars in liver disease. 2013 Review GET IT
Times cited: 107
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nature medicine. 2013 Academic Article GET IT
Times cited: 165
Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 27
Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling. Science signaling. 2013 Academic Article GET IT
Times cited: 24
Targeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilization. PloS one. 2013 Academic Article GET IT
Times cited: 51
Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease. Journal of gastroenterology. 2013 Review GET IT
Times cited: 600
New players on the metabolic stage: How do you like Them Acots?. Adipocyte. 2013 Academic Article GET IT
Times cited: 43
Functional characterization of thioesterase superfamily member 1/Acyl-CoA thioesterase 11: implications for metabolic regulation. Journal of lipid research. 2012 Academic Article GET IT
Times cited: 27
Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue. Nature medicine. 2012 Academic Article GET IT
Times cited: 148
Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 71
Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 Academic Article GET IT
Times cited: 47
MicroRNAs in metabolism and metabolic diseases. Cold Spring Harbor symposia on quantitative biology. 2011 Academic Article GET IT
Times cited: 110
The arrestin domain-containing 3 protein regulates body mass and energy expenditure. Cell metabolism. 2011 Academic Article GET IT
Times cited: 88
Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production. Hepatology (Baltimore, Md.). 2011 Academic Article GET IT
Times cited: 22
Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality. Diabetes. 2011 Academic Article GET IT
Times cited: 112
Decreased expression of ARV1 results in cholesterol retention in the endoplasmic reticulum and abnormal bile acid metabolism. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 20
STARTing to understand MLN64 function in cholesterol transport. Journal of lipid research. 2010 Comment GET IT
Times cited: 17
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science (New York, N.Y.). 2010 Academic Article GET IT
Times cited: 785
High incidence of cholesterol gallstone disease in type 1 Gaucher disease: characterizing the biliary phenotype of type 1 Gaucher disease. Journal of inherited metabolic disease. 2010 Academic Article GET IT
Times cited: 46
PC-TP/StARD2: Of membranes and metabolism. Trends in endocrinology and metabolism: TEM. 2010 Review GET IT
Times cited: 40
Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha). Biochimica et biophysica acta. 2010 Academic Article GET IT
Times cited: 16
Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs. The Biochemical journal. 2009 Academic Article GET IT
Times cited: 43
Mice lacking Pctp /StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue. Journal of lipid research. 2009 Academic Article GET IT
Times cited: 27
Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression. Diabetes. 2009 Academic Article GET IT
Times cited: 122
Biliary lipids and cholesterol gallstone disease. Journal of lipid research. 2008 Review GET IT
Times cited: 149
Biochemical characterization of L-DOPA 2,3-dioxygenase, a single-domain type I extradiol dioxygenase from lincomycin biosynthesis. Archives of biochemistry and biophysics. 2008 Academic Article GET IT
Times cited: 22
Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening. Analytical biochemistry. 2008 Academic Article GET IT
Times cited: 8
Regulation of hepatic lipogenesis by the transcription factor XBP1. Science (New York, N.Y.). 2008 Academic Article GET IT
Times cited: 744
Balancing cholesterol synthesis and absorption in the gastrointestinal tract. Journal of clinical lipidology. 2008 Academic Article GET IT
Times cited: 83
Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008 Academic Article GET IT
Times cited: 32
Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat. American journal of physiology. Gastrointestinal and liver physiology. 2008 Academic Article GET IT
Times cited: 10
Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell metabolism. 2008 Academic Article GET IT
Times cited: 355
Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell metabolism. 2007 Academic Article GET IT
Times cited: 39
Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2. The Journal of biological chemistry. 2007 Academic Article GET IT
Times cited: 57
Rationale and design of a prospective clinical trial program to evaluate the glucose-lowering effects of colesevelam HCl in patients with type 2 diabetes mellitus. Current medical research and opinion. 2007 Academic Article GET IT
Times cited: 33
Structure and function of phosphatidylcholine transfer protein (PC-TP)/StarD2. Biochimica et biophysica acta. 2007 Review GET IT
Times cited: 69
Par1b promotes hepatic-type lumen polarity in Madin Darby canine kidney cells via myosin II- and E-cadherin-dependent signaling. Molecular biology of the cell. 2007 Academic Article GET IT
Times cited: 39
Medical sequencing at the extremes of human body mass. American journal of human genetics. 2007 Academic Article GET IT
Times cited: 179
Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse. Biochimica et biophysica acta. 2007 Academic Article GET IT
Times cited: 13
A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein. FEBS letters. 2006 Academic Article GET IT
Times cited: 21
Homozygous disruption of Pctp modulates atherosclerosis in apolipoprotein E-deficient mice. Journal of lipid research. 2006 Academic Article GET IT
Times cited: 8
An assessment of statin safety by hepatologists. 2006 GET IT
Times cited: 318
Mice overexpressing hepatic Abcb11 rapidly develop cholesterol gallstones. Mammalian genome : official journal of the International Mammalian Genome Society. 2005 Academic Article GET IT
Times cited: 18
Phosphatidylcholine transfer protein regulates size and hepatic uptake of high-density lipoproteins. American journal of physiology. Gastrointestinal and liver physiology. 2005 Academic Article GET IT
Times cited: 16
Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein. The Biochemical journal. 2005 Academic Article GET IT
Times cited: 13
Altered hepatic cholesterol metabolism compensates for disruption of phosphatidylcholine transfer protein in mice. American journal of physiology. Gastrointestinal and liver physiology. 2005 Academic Article GET IT
Times cited: 11
A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse. Hepatology (Baltimore, Md.). 2005 Academic Article GET IT
Times cited: 8
Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice. Journal of lipid research. 2004 Academic Article GET IT
Times cited: 24
Role of CYP27A in cholesterol and bile acid metabolism. Journal of lipid research. 2004 Academic Article GET IT
Times cited: 43
Par-1 promotes a hepatic mode of apical protein trafficking in MDCK cells. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 45
Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARalpha-mediated redistribution of ABCB4. Journal of lipid research. 2004 Academic Article GET IT
Times cited: 52
Intracerebroventricular leptin regulates hepatic cholesterol metabolism. The Biochemical journal. 2004 Academic Article GET IT
Times cited: 38
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 85
Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse. American journal of physiology. Gastrointestinal and liver physiology. 2003 Academic Article GET IT
Times cited: 159
Restoration of gallstone susceptibility by leptin in C57BL/6J ob/ob mice. Journal of lipid research. 2003 Academic Article GET IT
Times cited: 26
Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice. Journal of lipid research. 2003 Academic Article GET IT
Times cited: 87
Bile acid regulation of hepatic physiology: I. Hepatocyte transport of bile acids. American journal of physiology. Gastrointestinal and liver physiology. 2003 Review GET IT
Times cited: 63
Combination platelet glycoprotein IIb/IIIa receptor and lepirudin administration during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2003 Review GET IT
Times cited: 15
Hepatic overexpression of sterol carrier protein-2 inhibits VLDL production and reciprocally enhances biliary lipid secretion. Journal of lipid research. 2002 Academic Article GET IT
Times cited: 38
Cutaneous lidocaine allergy confirmed by patch testing. 2002 GET IT
Times cited: 18
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 279
Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 71
Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nature structural biology. 2002 Academic Article GET IT
Times cited: 198
Cholesterol gallstones. Current opinion in gastroenterology. 2002 Academic Article GET IT
Times cited: 5
Human phosphatidylcholine transfer protein: purification, crystallization and preliminary X-ray diffraction data. Biochimica et biophysica acta. 2002 Academic Article GET IT
Times cited: 3
Phosphatidylcholine transfer protein promotes apolipoprotein A-I-mediated lipid efflux in Chinese hamster ovary cells. The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 22
Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels. Biochemistry. 2001 Academic Article GET IT
Times cited: 37
Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance. American journal of physiology. Gastrointestinal and liver physiology. 2001 Academic Article GET IT
Times cited: 78
Etiologic significance of defects in cholesterol, phospholipid, and bile acid metabolism in the liver of patients with intrahepatic calculi. Hepatology (Baltimore, Md.). 2001 Academic Article GET IT
Times cited: 65
Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins. American journal of physiology. Cell physiology. 2001 Academic Article GET IT
Times cited: 67
Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice. Journal of lipid research. 2001 Academic Article GET IT
Times cited: 259
High-level expression and mutagenesis of recombinant human phosphatidylcholine transfer protein using a synthetic gene: evidence for a C-terminal membrane binding domain. Biochemistry. 2000 Academic Article GET IT
Times cited: 46
Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport. Digestive diseases and sciences. 2000 Academic Article GET IT
Times cited: 55
The Tangier disease gene encodes yet another pathophysiologically relevant atp-binding cassette protein. Hepatology (Baltimore, Md.). 2000 Academic Article GET IT
Times cited: 1
Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein. Biochimica et biophysica acta. 1999 Academic Article GET IT
Times cited: 27
Hepatocellular transport and secretion of biliary lipids. Current opinion in lipidology. 1999 Review GET IT
Times cited: 41
Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp. Gene. 1999 Academic Article GET IT
Times cited: 12
Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis. The American journal of physiology. 1999 Academic Article GET IT
Times cited: 106
No pathophysiologic relationship of soluble biliary proteins to cholesterol crystallization in human bile. Journal of lipid research. 1999 Academic Article GET IT
Times cited: 41
Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice. The Biochemical journal. 1998 Academic Article GET IT
Times cited: 58
Laser light scattering evidence for a common wormlike growth structure of mixed micelles in bile salt- and straight-chain detergent-phosphatidylcholine aqueous systems: relevance to the micellar structure of bile. Biochemistry. 1998 Academic Article GET IT
Times cited: 78
Submicellar bile salts stimulate phosphatidylcholine transfer activity of sterol carrier protein 2. Journal of lipid research. 1998 Academic Article GET IT
Times cited: 12
Baculovirus-mediated expression of recombinant rat phosphatidylcholine transfer protein. Journal of lipid research. 1998 Academic Article GET IT
Times cited: 9
The gene encoding the multispecific organic anion transporter (Cmoat) of the hepatocyte canalicular membrane maps to mouse chromosome 19. Mammalian genome : official journal of the International Mammalian Genome Society. 1998 Academic Article GET IT
Times cited: 9
Single step purification of rat liver aldolase using immobilized artificial membrane chromatography. Journal of chromatography. B, Biomedical sciences and applications. 1997 Academic Article GET IT
Times cited: 8
Evidence for an ATP-independent long-chain phosphatidylcholine translocator in hepatocyte membranes. The American journal of physiology. 1997 Academic Article GET IT
Times cited: 15
Transmembrane translocation of phosphatidylcholines and biliary lipid secretion: evidence for "flippases" in the canalicular plasma membrane. Hepatology (Baltimore, Md.). 1996 Academic Article GET IT
Times cited: 3
Hepatocellular transport and secretion of biliary phospholipids. Seminars in liver disease. 1996 Review GET IT
Times cited: 25
Cloning and characterization of a cDNA encoding the specific phosphatidylcholine transfer protein from bovine liver. Gene. 1995 Academic Article GET IT
Times cited: 12
Immobilized artificial membrane chromatography: a rapid and accurate HPLC method for predicting bile salt-membrane interactions. Journal of lipid research. 1995 Academic Article GET IT
Times cited: 32
Update on physical state of bile. The Italian journal of gastroenterology. 1995 Review GET IT
Times cited: 13
In vitro evidence that phospholipid secretion into bile may be coordinated intracellularly by the combined actions of bile salts and the specific phosphatidylcholine transfer protein of liver. Biochemistry. 1994 Academic Article GET IT
Times cited: 79
Phospholipid molecular species influence crystal habits and transition sequences of metastable intermediates during cholesterol crystallization from bile salt-rich model bile. Journal of lipid research. 1994 Academic Article GET IT
Times cited: 51
Cholesterol carriers in human bile: are "lamellae" involved?. Hepatology (Baltimore, Md.). 1993 Review GET IT
Times cited: 38
Bile salt hydrophobicity controls vesicle secretion rates and transformations in native bile. The American journal of physiology. 1992 Academic Article GET IT
Times cited: 40
Acyl chain unsaturation modulates distribution of lecithin molecular species between mixed micelles and vesicles in model bile. Implications for particle structure and metastable cholesterol solubilities. Journal of lipid research. 1991 Academic Article GET IT
Times cited: 58
Rapid (1 hour) high performance gel filtration chromatography resolves coexisting simple micelles, mixed micelles, and vesicles in bile. Journal of lipid research. 1990 Academic Article GET IT
Times cited: 38
Physical chemistry of biliary lipids during bile formation. Hepatology (Baltimore, Md.). 1990 Review GET IT
Times cited: 16
Principles of laser light-scattering spectroscopy: applications to the physicochemical study of model and native biles. Hepatology (Baltimore, Md.). 1990 Review GET IT
Times cited: 29
Structural alterations in lecithin-cholesterol vesicles following interactions with monomeric and micellar bile salts: physical-chemical basis for subselection of biliary lecithin species and aggregative states of biliary lipids during bile formation. Journal of lipid research. 1990 Academic Article GET IT
Times cited: 76
Quasielastic light scattering evidence for vesicular secretion of biliary lipids. The American journal of physiology. 1989 Academic Article GET IT
Times cited: 37
Echocardiographic findings of metastatic chondrosarcoma involving the left atrium. 1986 GET IT
Times cited: 3

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Research

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Co-investigator Network

Funding awarded

The role of PKM2 in dietary lipid absorption and fructose-induced obesity awarded by National Institute of Diabetes & Digestive & Kidney Diseases Co-Investigator 2022 - 2027

Multidisciplinary Research Training in Gastroenterology and Hepatology awarded by National Institute of Diabetes & Digestive & Kidney Diseases Key Personnel 2019 - 2024

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Background

education and training

M.D., Harvard Medical School 1987
Ph.D., Harvard University 1987
A.B., Harvard College 1982

Contact

full name

David Cohen

primary email

dcohen@med.cornell.edu

VIVO Weill Cornell Medical College

David Cohen Adjunct Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email