Khani, Francesca

Publications

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selected publications

Novel genetically engineered mouse models for clear cell renal cell carcinoma. Scientific reports. 2023 Academic Article GET IT
The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer. Frontiers in cell and developmental biology. 2023 Academic Article GET IT
Times cited: 239
Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer. Nature cancer. 2023 Academic Article GET IT
Distinct mesenchymal cell states mediate prostate cancer progression. bioRxiv : the preprint server for biology. 2023 Article GET IT
The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer. Cancer research. 2023 Academic Article GET IT
Times cited: 3
Clinical and molecular significance of the RNA m⁶A methyltransferase complex in prostate cancer. Frontiers in genetics. 2023 Academic Article GET IT
Times cited: 220
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer. Cancers. 2022 Academic Article GET IT
Times cited: 90
Recognition Awards in Pathology Specialty Societies. American journal of clinical pathology. 2022 Academic Article GET IT
Times cited: 2
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer. Frontiers in endocrinology. 2022 Review GET IT
Times cited: 72
Gender distribution of editors and authors of reference textbooks in anatomic pathology: further edits are required. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2022 Academic Article GET IT
Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR). Molecular carcinogenesis. 2022 Academic Article GET IT
Times cited: 2
A multidisciplinary approach to optimize primary prostate cancer biobanking. Urologic oncology. 2022 Academic Article GET IT
Times cited: 1
Pilot study of the diagnostic utility of ⁸⁹ Zr-df-IAB2M and ⁶⁸ Ga-PSMA-11 PET imaging and multiparametric MRI in localized prostate cancer. The Prostate. 2022 Academic Article GET IT
Times cited: 6
Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma. Frontiers in oncology. 2021 Academic Article GET IT
Times cited: 242
Secondary malignancy after urologic reconstruction procedures: a multi-institutional case series. Human pathology. 2021 Academic Article GET IT
Times cited: 2
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer. Nature communications. 2021 Academic Article GET IT
Times cited: 30
Testicular Germ-Cell Tumors with Spermatic Cord Involvement: A Retrospective International Multi-Institutional Experience. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2021 Academic Article GET IT
Times cited: 4
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity. Cell reports. 2021 Academic Article GET IT
Times cited: 9
Variant PNLDC1, Defective piRNA Processing, and Azoospermia. The New England journal of medicine. 2021 Academic Article GET IT
Times cited: 30
Metastatic Mature Teratoma and Growing Teratoma Syndrome in Patients with Testicular Non-Seminomatous Germ Cell Tumors. Korean journal of radiology. 2021 Review GET IT
Times cited: 4
Clipless Robotic-assisted Radical Prostatectomy and Impact on Outcomes. European urology focus. 2021 Academic Article GET IT
Times cited: 4
Quantifying Heterogeneity of Testicular Histopathology in Men with Nonobstructive Azoospermia. The Journal of urology. 2021 Academic Article GET IT
Times cited: 6
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nature communications. 2021 Academic Article GET IT
Times cited: 21
Computer extracted gland features from H&E predicts prostate cancer recurrence comparably to a genomic companion diagnostic test: a large multi-site study. NPJ precision oncology. 2021 Academic Article GET IT
Times cited: 5
Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2. European urology focus. 2021 Academic Article GET IT
Times cited: 10
Incorporating cytologic adequacy assessment into precision oncology workflow using telepathology: An institutional experience. Cancer cytopathology. 2021 Academic Article GET IT
Times cited: 1
The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer. 2021 GET IT
Times cited: 103
Nested Variant of Urothelial Carcinoma Is a Luminal Bladder Tumor With Distinct Coexpression of the Basal Marker Cytokeratin 5/6. American journal of clinical pathology. 2021 Academic Article GET IT
Times cited: 6
Tumor size and genomic risk in localized prostate cancer. Urologic oncology. 2021 Academic Article GET IT
Times cited: 2
Diagnostic approach in TFE3-rearranged renal cell carcinoma: a multi-institutional international survey. Journal of clinical pathology. 2021 Academic Article GET IT
Times cited: 13
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology. Translational oncology. 2020 Academic Article GET IT
Times cited: 11
Contemporary Results and Clinical Utility of Renal Mass Biopsies in the Setting of Ablative Therapy: A single center experience. Cancer treatment and research communications. 2020 Academic Article GET IT
Times cited: 4
Practice patterns related to prostate cancer grading: results of a 2019 Genitourinary Pathology Society clinician survey. Urologic oncology. 2020 Academic Article GET IT
Times cited: 4
A novel prognostic two-gene signature for triple negative breast cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2020 Academic Article GET IT
Times cited: 19
Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in African American Patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 21
Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer. Nature communications. 2020 Academic Article GET IT
Times cited: 45
Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma. Translational oncology. 2019 Academic Article GET IT
Times cited: 20
Concordance Between Biopsy and Radical Prostatectomy Pathology in the Era of Targeted Biopsy: A Systematic Review and Meta-analysis. European urology oncology. 2019 Review GET IT
Times cited: 46
Corrigendum to 'The Role of Systematic and Targeted Biopsies in Light of Overlap on Magnetic Resonance Imaging Ultrasound Fusion Biopsy' [European Urology Oncology 1 (2018) 263-267]. European urology oncology. 2019 Article GET IT
Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling. Nature communications. 2019 Academic Article GET IT
Times cited: 102
Impact of Neoadjuvant Chemotherapy on Concordance of PD-L1 Staining Fidelity between the Primary Tumor and Lymph Node Metastases in Bladder Cancer. Urology. 2019 Academic Article GET IT
Times cited: 5
The Clinical Utility of the Genomic Prostate Score in Men with Very Low to Intermediate Risk Prostate Cancer. The Journal of urology. 2019 Academic Article GET IT
Times cited: 2
Intraductal carcinoma of the prostate in the absence of high-grade invasive carcinoma represents a molecularly distinct type of in situ carcinoma enriched with oncogenic driver mutations. The Journal of pathology. 2019 Academic Article GET IT
Times cited: 31
Oncogenic Addiction to ERBB2 Signaling Predicts Response to Trastuzumab in Urothelial Cancer. 2019 GET IT
Times cited: 4
Gynecologic Organ Involvement During Radical Cystectomy for Bladder Cancer: Is It Time to Routinely Spare the Ovaries?. Clinical genitourinary cancer. 2018 Academic Article GET IT
Times cited: 6
Hotspot enumeration of CD8+ tumor-infiltrating lymphocytes using digital image analysis in triple-negative breast cancer yields consistent results. Human pathology. 2018 Academic Article GET IT
Times cited: 10
The Learning Curve for Magnetic Resonance Imaging/Ultrasound Fusion-guided Prostate Biopsy. European urology oncology. 2018 Academic Article GET IT
Times cited: 44
The Role of Systematic and Targeted Biopsies in Light of Overlap on Magnetic Resonance Imaging Ultrasound Fusion Biopsy. European urology oncology. 2018 Academic Article GET IT
Times cited: 14
Exploring Multiphoton Microscopy as a Novel Tool to Differentiate Chromophobe Renal Cell Carcinoma From Oncocytoma in Fixed Tissue Sections. Archives of pathology & laboratory medicine. 2017 Academic Article GET IT
Times cited: 23
Population-based study of the incidence and survival for intraductal carcinoma of the prostate. Urologic oncology. 2017 Academic Article GET IT
Times cited: 22
A Precious Diagnostic "Pearl": The Necklace Pattern in Germ Cell Tumors of the Testis. 2017 GET IT
Precursor Lesions of Urologic Malignancies. Archives of pathology & laboratory medicine. 2017 Review GET IT
Times cited: 4
Frequency and Prognostic Value of PTEN Loss in Patients with Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy. The Journal of urology. 2017 Academic Article GET IT
Times cited: 3
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer discovery. 2017 Academic Article GET IT
Times cited: 77
Intraductal Carcinoma of the Prostate: A Risk for Rapid Recurrence. 2017 GET IT
Times cited: 4
In response to 'a plea for greater standardization' in intraductal carcinoma of the prostate: greater standardization requires greater evidence. Histopathology. 2017 Letter GET IT
Times cited: 5
Accuracy of Grading Gleason Score 7 Prostatic Adenocarcinoma on Needle Biopsy: Influence of Percent Pattern 4 and Other Histological Factors. The Prostate. 2017 Academic Article GET IT
Times cited: 12
Interobserver Reproducibility of Percent Gleason Pattern 4 in Prostatic Adenocarcinoma on Prostate Biopsies. The American journal of surgical pathology. 2016 Academic Article GET IT
Times cited: 26
Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial Carcinoma. The American journal of surgical pathology. 2016 Academic Article GET IT
Times cited: 8
Diagnostic dilemmas in enlarged and diffusely hemorrhagic adrenal glands. Human pathology. 2016 Academic Article GET IT
Times cited: 7
Carcinoma of the Uterine Cervix Involving the Genitourinary Tract: A Potential Diagnostic Dilemma. The American journal of surgical pathology. 2016 Academic Article GET IT
Times cited: 24
A "Chicken or Egg" Conundrum: Race, Molecular Subtype, and Tumor Location in Prostate Cancer. European urology. 2015 Editorial Article GET IT
Times cited: 2
Prostate Biopsy Specimens With Gleason 3+3=6 and Intraductal Carcinoma: Radical Prostatectomy Findings and Clinical Outcomes. The American journal of surgical pathology. 2015 Academic Article GET IT
Times cited: 64
Iatrogenic Extraprostatic Extension of Prostate Cancer From a Needle Biopsy. 2015 GET IT
Times cited: 1
Evidence for molecular differences in prostate cancer between African American and Caucasian men. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 120
SPOP mutations in prostate cancer across demographically diverse patient cohorts. Neoplasia (New York, N.Y.). 2014 Academic Article GET IT
Times cited: 114
Insulin-like growth factor messenger RNA-binding protein 3 expression helps prognostication in patients with upper tract urothelial carcinoma. European urology. 2013 Academic Article GET IT
Times cited: 21
Association of oncofetal protein expression with clinical outcomes in patients with urothelial carcinoma of the bladder. The Journal of urology. 2013 Academic Article GET IT
Times cited: 20
Functional outcomes following robotic prostatectomy using athermal, traction free risk-stratified grades of nerve sparing. World journal of urology. 2013 Academic Article GET IT
Times cited: 37
A 24-year-old man with previously diagnosed hemophilia. 2012 GET IT
Times cited: 2
Immune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4+ T cells. Blood. 2010 Academic Article GET IT
Times cited: 28

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Research

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Co-investigator Network

Funding awarded

Heating cold prostate tumors with PSMA-targeted alpha therapy and pembrolizumab awarded by United States Department of Defense Co-Investigator 2020 - 2024
Weill Cornell Medicine (WCM) SPORE in Prostate Cancer awarded by National Cancer Institute Co-Investigator 2017 - 2023

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Background

education and training

M.D., Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey 2010
B.S., The College of New Jersey 2006

Contact

full name

Francesca Khani

primary email

frk9007@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Francesca Khani Associate Professor of Pathology and Laboratory Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage