selected publications
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Membrane-mediated protein interactions drive membrane protein organization.
Nature communications.
2022
Academic Article
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Times cited: 4 - Control of Gαq signaling dynamics and GPCR cross-talk by GRKs. Science advances. 2022 Academic Article GET IT
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Perforin-2 clockwise hand-over-hand pre-pore to pore transition mechanism.
Nature communications.
2022
Academic Article
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Times cited: 5 -
Complexin Membrane Interactions: Implications for Synapse Evolution and Function.
Journal of molecular biology.
2022
Review
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Times cited: 2 -
A unique C2 domain at the C terminus of Munc13 promotes synaptic vesicle priming.
Proceedings of the National Academy of Sciences of the United States of America.
2021
Academic Article
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Times cited: 6 -
Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors.
Cell reports.
2020
Article
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Times cited: 5 -
Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors.
Cell reports.
2020
Academic Article
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Times cited: 29 -
The control of release probability at nerve terminals.
Nature reviews. Neuroscience.
2019
Review
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Times cited: 47 -
Unc13: a multifunctional synaptic marvel.
Current opinion in neurobiology.
2019
Review
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Times cited: 26 -
Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
Nature communications.
2018
Academic Article
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Times cited: 37 -
Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.
PLoS biology.
2018
Academic Article
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Times cited: 85 -
A C1-C2 Module in Munc13 Inhibits Calcium-Dependent Neurotransmitter Release.
Neuron.
2017
Academic Article
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Times cited: 42 -
Evolutionary Divergence of the C-terminal Domain of Complexin Accounts for Functional Disparities between Vertebrate and Invertebrate Complexins.
Frontiers in molecular neuroscience.
2017
Academic Article
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Times cited: 55 -
Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function.
Frontiers in molecular neuroscience.
2017
Academic Article
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Times cited: 74 -
Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 62 -
Downregulation of a GPCR by β-Arrestin2-Mediated Switch from an Endosomal to a TGN Recycling Pathway.
Cell reports.
2016
Academic Article
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Times cited: 30 -
Speed Limits for Nonvesicular Intracellular Sterol Transport.
Trends in biochemical sciences.
2016
Review
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Times cited: 42 -
Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants.
Nature communications.
2016
Academic Article
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Times cited: 45 -
Synaptic activity regulates the abundance and binding of complexin.
Biophysical journal.
2015
Academic Article
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Times cited: 7 -
The accessory helix of complexin functions by stabilizing central helix secondary structure.
eLife.
2014
Academic Article
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Times cited: 113 -
Constitutive phospholipid scramblase activity of a G protein-coupled receptor.
Nature communications.
2014
Academic Article
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Times cited: 87 -
Membrane curvature sensing by the C-terminal domain of complexin.
Nature communications.
2014
Academic Article
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Times cited: 55 -
Synaptic vesicles position complexin to block spontaneous fusion.
Neuron.
2013
Academic Article
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Times cited: 66 -
Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM.
Traffic (Copenhagen, Denmark).
2011
Academic Article
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Times cited: 100 -
Complexin has opposite effects on two modes of synaptic vesicle fusion.
Current biology : CB.
2011
Academic Article
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Times cited: 106 -
Endophilin functions as a membrane-bending molecule and is delivered to endocytic zones by exocytosis.
Cell.
2010
Academic Article
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Times cited: 93 -
Molecular circuitry of endocytosis at nerve terminals.
Annual review of cell and developmental biology.
2009
Review
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Times cited: 187 -
Worm watching: imaging nervous system structure and function in Caenorhabditis elegans.
Advances in genetics.
2009
Review
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Times cited: 6 -
Behavioral impact of neurotransmitter-activated G-protein-coupled receptors: muscarinic and GABAB receptors regulate Caenorhabditis elegans locomotion.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2008
Academic Article
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Times cited: 57 -
Factors regulating the abundance and localization of synaptobrevin in the plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America.
2006
Academic Article
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Times cited: 112 -
Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans.
Neuron.
2002
Academic Article
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Times cited: 233 -
Interplay between facilitation, depression, and residual calcium at three presynaptic terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2000
Academic Article
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Times cited: 403 -
Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1998
Academic Article
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Times cited: 326 -
Mechanism and kinetics of heterosynaptic depression at a cerebellar synapse.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1997
Academic Article
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Times cited: 120 -
Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1996
Academic Article
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Times cited: 254 -
Shaker potassium channel gating. II: Transitions in the activation pathway.
The Journal of general physiology.
1994
Academic Article
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Times cited: 277