selected publications
- The Immunogenomic Landscape of Neuroendocrine Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
- Whole-genome characterization of myoepithelial carcinomas of the soft tissue. Cold Spring Harbor molecular case studies. 2022 Academic Article GET IT
- Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging. Nature methods. 2022 Article GET IT
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Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment.
2022
GET IT
Times cited: 1975 -
Unsupervised discovery of tissue architecture in multiplexed imaging.
Nature methods.
2022
Academic Article
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Times cited: 3 -
GLI1 -Rearranged Enteric Tumor : Expanding the Spectrum of Gastrointestinal Neoplasms With GLI1 Gene Fusions.
The American journal of surgical pathology.
2022
Academic Article
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Times cited: 1 -
Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing.
Nature biotechnology.
2022
Academic Article
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Times cited: 10 -
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets.
Science (New York, N.Y.).
2022
Academic Article
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Times cited: 22 -
Weakly-supervised tumor purity prediction from frozen H&E stained slides.
EBioMedicine.
2022
Academic Article
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Times cited: 3 -
Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.
The Journal of experimental medicine.
2022
Academic Article
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Times cited: 3 -
A multidisciplinary approach to optimize primary prostate cancer biobanking.
Urologic oncology.
2022
Academic Article
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Times cited: 1 -
Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab.
2022
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Times cited: 3 -
The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.
Molecular oncology.
2022
Academic Article
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Times cited: 4 -
Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies.
The Journal of pathology.
2022
Academic Article
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Times cited: 8 -
RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.
Annals of surgical oncology.
2022
Academic Article
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Times cited: 243 -
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.
JCI insight.
2022
Academic Article
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Times cited: 3 -
Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.
British journal of cancer.
2022
Academic Article
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Times cited: 6 -
Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors.
Advanced materials (Deerfield Beach, Fla.).
2021
Academic Article
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Times cited: 16 - Fine-needle aspiration biopsy of growing teratoma syndrome as a diagnostic pitfall of metastatic adenocarcinoma. 2021 GET IT
- Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis. NPJ precision oncology. 2021 Article GET IT
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Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.
2021
Academic Article
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Times cited: 2 -
Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
NPJ precision oncology.
2021
Academic Article
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Times cited: 480 -
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.
NPJ genomic medicine.
2021
Academic Article
GET IT
Times cited: 52892 -
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing.
The oncologist.
2021
Academic Article
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Times cited: 6 -
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
NPJ precision oncology.
2021
Academic Article
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Times cited: 224 -
Incorporating cytologic adequacy assessment into precision oncology workflow using telepathology: An institutional experience.
Cancer cytopathology.
2021
Academic Article
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Times cited: 1 -
Common germline-somatic variant interactions in advanced urothelial cancer.
Nature communications.
2020
Academic Article
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Times cited: 13 -
Performance Characteristics of a Targeted Sequencing Platform for Simultaneous Detection of Single Nucleotide Variants, Insertions/Deletions, Copy Number Alterations, and Gene Fusions in Cancer Genome.
Archives of pathology & laboratory medicine.
2020
Academic Article
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Times cited: 4 -
Feasibility of in-office MRI-targeted partial gland cryoablation for prostate cancer: an IDEAL stage 2A study.
BMJ surgery, interventions, & health technologies.
2020
Academic Article
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Times cited: 278 -
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Translational oncology.
2020
Academic Article
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Times cited: 11 -
Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
Cell.
2020
Academic Article
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Times cited: 80 -
Neurofibroma originating from a urachal mass.
2020
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Times cited: 1 -
Contemporary Results and Clinical Utility of Renal Mass Biopsies in the Setting of Ablative Therapy: A single center experience.
Cancer treatment and research communications.
2020
Academic Article
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Times cited: 4 -
Molecular Profiles of Mixed Endometrial Carcinoma.
The American journal of surgical pathology.
2020
Academic Article
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Times cited: 8 -
Neuroendocrine differentiation in usual-type prostatic adenocarcinoma: Molecular characterization and clinical significance.
The Prostate.
2020
Academic Article
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Times cited: 21 -
Next-generation sequencing of residual cytologic fixative preserved DNA from pancreatic lesions: A pilot study.
Cancer cytopathology.
2020
Academic Article
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Times cited: 5 -
Fusions involving BCOR and CREBBP are rare events in infiltrating glioma.
Acta neuropathologica communications.
2020
Academic Article
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Times cited: 9 -
Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2020
Academic Article
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Times cited: 12 -
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.
Nature communications.
2020
Academic Article
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Times cited: 20 -
Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer.
The Journal of clinical investigation.
2020
Academic Article
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Times cited: 88 -
SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy.
Molecular cancer therapeutics.
2020
Academic Article
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Times cited: 32 -
Prostate Multiparametric Magnetic Resonance Imaging Features Following Partial Gland Cryoablation.
Urology.
2020
Academic Article
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Times cited: 6 -
Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
JCO precision oncology.
2019
Academic Article
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Times cited: 36 -
Clinical features of neuroendocrine prostate cancer.
European journal of cancer (Oxford, England : 1990).
2019
Academic Article
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Times cited: 138 -
Race and prostate imaging: implications for targeted biopsy and image-based prostate cancer interventions.
BMJ surgery, interventions, & health technologies.
2019
Academic Article
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Times cited: 144 -
Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution.
JCO precision oncology.
2019
Academic Article
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Times cited: 105 -
The Clinical Utility of the Genomic Prostate Score in Men with Very Low to Intermediate Risk Prostate Cancer.
The Journal of urology.
2019
Academic Article
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Times cited: 2 -
Genomic correlates of clinical outcome in advanced prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 561 -
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.
Science translational medicine.
2019
Academic Article
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Times cited: 83 -
Oncogenic Addiction to ERBB2 Signaling Predicts Response to Trastuzumab in Urothelial Cancer.
2019
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Times cited: 4 -
Identification of a therapeutic target using molecular sequencing for treatment of recurrent uterine serous adenocarcinoma.
2019
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Times cited: 5 -
Gynecologic Organ Involvement During Radical Cystectomy for Bladder Cancer: Is It Time to Routinely Spare the Ovaries?.
Clinical genitourinary cancer.
2018
Academic Article
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Times cited: 6 -
Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.
Molecular cancer research : MCR.
2018
Academic Article
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Times cited: 32 -
A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 130 -
Patient derived organoids to model rare prostate cancer phenotypes.
Nature communications.
2018
Academic Article
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Times cited: 203 -
Bone biopsy protocol for advanced prostate cancer in the era of precision medicine.
Cancer.
2017
Academic Article
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Times cited: 33 -
SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 22 -
Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance.
Cancer cell.
2017
Academic Article
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Times cited: 45 -
Rapid autopsy of a patient with recurrent anaplastic ependymoma.
2017
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Times cited: 4 - A Precious Diagnostic "Pearl": The Necklace Pattern in Germ Cell Tumors of the Testis. 2017 GET IT
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Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics.
Journal of translational medicine.
2017
Academic Article
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Times cited: 5 -
Molecular alterations in prostate cancer and association with MRI features.
Prostate cancer and prostatic diseases.
2017
Academic Article
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Times cited: 13 -
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.
JCO precision oncology.
2017
Academic Article
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Times cited: 584 -
Characterization of CD34-deficient myofibroblastomas of the breast.
The breast journal.
2017
Academic Article
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Times cited: 5 -
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations.
Cancer discovery.
2017
Academic Article
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Times cited: 77 - Erratum to: Unraveling the clonal hierarchy of somatic genomic aberrations. Genome biology. 2017 Academic Article GET IT
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Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition.
European urology.
2017
Academic Article
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Times cited: 15 -
On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study.
Anticancer research.
2017
Academic Article
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Times cited: 5 -
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Cancer discovery.
2017
Academic Article
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Times cited: 589 - Two cases of atypical hemolytic uremic syndrome (aHUS) and eosinophilic granulomatosis with polyangiitis (EGPA): a possible relationship. CEN case reports. 2017 Academic Article GET IT
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Clonal evolution of chemotherapy-resistant urothelial carcinoma.
Nature genetics.
2016
Academic Article
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Times cited: 201 -
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Cancer cell.
2016
Academic Article
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Times cited: 327 -
Characterization of the leiomyomatous variant of myofibroblastoma: a rare subset distinct from other smooth muscle tumors of the breast.
Human pathology.
2016
Academic Article
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Times cited: 7 -
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
NPJ genomic medicine.
2016
Academic Article
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Times cited: 58 -
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.
Nature medicine.
2016
Academic Article
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Times cited: 933 -
Intracellular location of BRCA2 protein expression and prostate cancer progression in the Swedish Watchful Waiting Cohort.
Carcinogenesis.
2016
Academic Article
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Times cited: 6 -
Clonal evaluation of prostate cancer foci in biopsies with discontinuous tumor involvement by dual ERG/SPINK1 immunohistochemistry.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2016
Academic Article
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Times cited: 23 -
The Initial Detection and Partial Characterization of Circulating Tumor Cells in Neuroendocrine Prostate Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
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Times cited: 101 -
An emerging role for cytopathology in precision oncology.
Cancer cytopathology.
2015
Academic Article
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Times cited: 18 -
The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer.
Cell reports.
2015
Academic Article
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Times cited: 176 -
Integrative Clinical Genomics of Advanced Prostate Cancer.
Cell.
2015
Article
GET IT
Times cited: 340 -
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
JAMA oncology.
2015
Academic Article
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Times cited: 216 -
Integrative clinical genomics of advanced prostate cancer.
Cell.
2015
Academic Article
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Times cited: 2094 -
MAGI3-AKT3 fusion in breast cancer amended.
Nature.
2015
Letter
GET IT
Times cited: 18 -
Multicenter Evaluation of the Prostate Health Index to Detect Aggressive Prostate Cancer in Biopsy Naïve Men.
The Journal of urology.
2015
Academic Article
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Times cited: 125 -
ERG induces taxane resistance in castration-resistant prostate cancer.
Nature communications.
2014
Academic Article
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Times cited: 91 -
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.
Nature communications.
2014
Academic Article
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Times cited: 494 -
Organoid cultures derived from patients with advanced prostate cancer.
Cell.
2014
Academic Article
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Times cited: 983 -
Unraveling the clonal hierarchy of somatic genomic aberrations.
Genome biology.
2014
Academic Article
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Times cited: 76 -
MYB-NFIB gene fusion in adenoid cystic carcinoma of the breast with special focus paid to the solid variant with basaloid features.
Human pathology.
2014
Academic Article
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Times cited: 62 -
Evidence for molecular differences in prostate cancer between African American and Caucasian men.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014
Academic Article
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Times cited: 120 -
Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification.
Human pathology.
2014
Academic Article
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Times cited: 24 -
Proposed morphologic classification of prostate cancer with neuroendocrine differentiation.
The American journal of surgical pathology.
2014
Academic Article
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Times cited: 362 -
Recurrent prostate cancer genomic alterations predict response to brachytherapy treatment.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2014
Academic Article
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Times cited: 22 -
SPOP mutations in prostate cancer across demographically diverse patient cohorts.
Neoplasia (New York, N.Y.).
2014
Academic Article
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Times cited: 114 -
Diagnostic utility of MYC amplification and anti-MYC immunohistochemistry in atypical vascular lesions, primary or radiation-induced mammary angiosarcomas, and primary angiosarcomas of other sites.
Human pathology.
2013
Academic Article
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Times cited: 77 -
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.
Nature biotechnology.
2013
Academic Article
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Times cited: 1491 -
Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.
Genes, chromosomes & cancer.
2013
Academic Article
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Times cited: 114 -
V-ets erythroblastosis virus E26 oncogene homolog (avian)/Trefoil factor 3/high-molecular-weight cytokeratin triple immunostain: a novel tissue-based biomarker in prostate cancer with potential clinical application.
Human pathology.
2013
Academic Article
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Times cited: 7 -
Comprehensive molecular characterization of clear cell renal cell carcinoma.
Nature.
2013
Academic Article
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Times cited: 1721 -
Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma.
Genes, chromosomes & cancer.
2013
Academic Article
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Times cited: 370 -
Frequent PLAG1 gene rearrangements in skin and soft tissue myoepithelioma with ductal differentiation.
Genes, chromosomes & cancer.
2013
Academic Article
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Times cited: 102 -
Punctuated evolution of prostate cancer genomes.
Cell.
2013
Academic Article
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Times cited: 906 -
Epigenomic alterations in localized and advanced prostate cancer.
Neoplasia (New York, N.Y.).
2013
Academic Article
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Times cited: 61 -
Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma.
Genes, chromosomes & cancer.
2013
Academic Article
GET IT
Times cited: 162 -
Dedifferentiation in gastrointestinal stromal tumor to an anaplastic KIT-negative phenotype: a diagnostic pitfall: morphologic and molecular characterization of 8 cases occurring either de novo or after imatinib therapy.
The American journal of surgical pathology.
2013
Academic Article
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Times cited: 69 -
High-grade KIT-negative sarcoma of the small bowel in a patient with chronic myeloid leukemia receiving long-term tyrosine kinase inhibitors.
2013
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Times cited: 1 -
Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.
Prostate cancer and prostatic diseases.
2013
Academic Article
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Times cited: 59 -
Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2013
Academic Article
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Times cited: 40 -
Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing.
Nature genetics.
2013
Academic Article
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Times cited: 557 -
Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer.
Neoplasia (New York, N.Y.).
2013
Academic Article
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Times cited: 190 -
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
Cancer research.
2012
Academic Article
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Times cited: 150 -
Challenges in recognizing treatment-related neuroendocrine prostate cancer.
2012
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Times cited: 163 -
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.
European urology.
2012
Academic Article
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Times cited: 328 -
Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy.
Urologic oncology.
2012
Academic Article
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Times cited: 12 -
Oncogene-mediated alterations in chromatin conformation.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 110 -
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
Nature genetics.
2012
Academic Article
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Times cited: 1144 -
Validation of a TFE3 break-apart FISH assay for Xp11.2 translocation renal cell carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B.
2011
Academic Article
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Times cited: 60 -
Novel ZEB1 expression in bladder tumorigenesis.
BJU international.
2010
Academic Article
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Times cited: 50 -
A case of adult metastatic Xp11 translocation renal cell carcinoma treated successfully with sunitinib.
2009
GET IT
Times cited: 28 -
Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 134 -
Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component--is this dedifferentiated SFT?.
The American journal of surgical pathology.
2009
Academic Article
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Times cited: 200 -
Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 197 -
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2008
Academic Article
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Times cited: 174 -
Integrative microarray analysis of pathways dysregulated in metastatic prostate cancer.
Cancer research.
2007
Academic Article
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Times cited: 61 -
TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion.
The American journal of surgical pathology.
2007
Academic Article
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Times cited: 359 -
Morphological features of TMPRSS2-ERG gene fusion prostate cancer.
The Journal of pathology.
2007
Academic Article
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Times cited: 108 -
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.
Oncogene.
2007
Academic Article
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Times cited: 544 -
Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus.
The Journal of antimicrobial chemotherapy.
2006
Academic Article
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Times cited: 70 -
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.
Cancer research.
2006
Academic Article
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Times cited: 432 -
Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005
Academic Article
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Times cited: 184 -
The phosphorylated form of connexin43 is up-regulated in breast hyperplasias and carcinomas and in their neoformed capillaries.
Human pathology.
2005
Academic Article
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Times cited: 15 -
Immunolocalization of the Epstein-Barr nuclear antigen-1 in conjunctival squamous carcinomas and dysplasias.
Human pathology.
2005
Academic Article
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Times cited: 9 -
Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas.
The Journal of pathology.
2002
Academic Article
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Times cited: 88 -
Antifungal triazoles and polymorphonuclear leukocytes synergize to cause increased hyphal damage to Scedosporium prolificans and Scedosporium apiospermum.
Antimicrobial agents and chemotherapy.
2002
Academic Article
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Times cited: 58