Babich, John

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Advanced Fibroblast Activation Protein-Ligand Developments: FAP Imaging Agents: A Review of the Structural Requirements. PET clinics. 2023 Review GET IT
Advances in PSMA theranostics. Translational oncology. 2022 Academic Article GET IT
Times cited: 27
Decreased CSF clearance and increased brain amyloid in Alzheimer's disease. Fluids and barriers of the CNS. 2022 Academic Article GET IT
Times cited: 22
Synthesis and Evaluation of ¹¹C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography. Molecules (Basel, Switzerland). 2022 Academic Article GET IT
PET Tracers for Imaging Cardiac Function in Cardio-oncology. Current cardiology reports. 2022 Review GET IT
Times cited: 5
A suitable time point for quantifying the radiochemical purity of ²²⁵Ac-labeled radiopharmaceuticals. EJNMMI radiopharmacy and chemistry. 2021 Academic Article GET IT
Times cited: 304
68Ga-PSMA-HBED-CC PET/MRI is superior to multiparametric magnetic resonance imaging in men with biochemical recurrent prostate cancer: A prospective single-institutional study. Translational oncology. 2021 Academic Article GET IT
Times cited: 18
In Vivo Imaging of Fibroblast Activity Using a 68Ga-Labeled Fibroblast Activation Protein Alpha (FAP-α) Inhibitor: Study in a Mouse Rotator Cuff Repair Model. The Journal of bone and joint surgery. American volume. 2021 Academic Article GET IT
Times cited: 2
Population-based input function for TSPO quantification and kinetic modeling with [¹¹C]-DPA-713. EJNMMI physics. 2021 Academic Article GET IT
Times cited: 35
A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-α (FAPα). Molecular imaging and biology. 2021 Academic Article GET IT
Times cited: 10
Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates. Human gene therapy. 2020 Academic Article GET IT
Times cited: 14
Meeting report from the Prostate Cancer Foundation PSMA theranostics state of the science meeting. The Prostate. 2020 Review GET IT
Times cited: 15
Preclinical Evaluation of a High-Affinity Sarcophagine-Containing PSMA Ligand for ⁶⁴Cu/⁶⁷Cu-Based Theranostics in Prostate Cancer. Molecular pharmaceutics. 2020 Academic Article GET IT
Times cited: 19
A general ¹¹C-labeling approach enabled by fluoride-mediated desilylation of organosilanes. Nature communications. 2020 Academic Article GET IT
Times cited: 14
Oxyaapa: A Picolinate-Based Ligand with Five Oxygen Donors that Strongly Chelates Lanthanides. Inorganic chemistry. 2020 Academic Article GET IT
Times cited: 14
Synthesis of [1-¹¹C]Butanol via a facile solid phase extraction protocol. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2020 Academic Article GET IT
Times cited: 2
Otto: a 4.04 GBq (109 mCi) ⁶⁸Ge/⁶⁸Ga generator, first of its kind - extended quality control and performance evaluation in the clinical production of [⁶⁸Ga]Ga-PSMA-11. EJNMMI radiopharmacy and chemistry. 2020 Academic Article GET IT
Times cited: 327
3D-printed automation for optimized PET radiochemistry. Science advances. 2019 Academic Article GET IT
Times cited: 5
Improved synthesis of the bifunctional chelator p-SCN-Bn-HOPO. Organic & biomolecular chemistry. 2019 Academic Article GET IT
Times cited: 9
Preclinical evaluation of peptide-based radiotracers for integrin αvβ6-positive pancreatic carcinoma. Nuklearmedizin. Nuclear medicine. 2019 Academic Article GET IT
Times cited: 8
[¹⁸F]Fluoroethyltriazolyl Monocyclam Derivatives as Imaging Probes for the Chemokine Receptor CXCR4. Molecules (Basel, Switzerland). 2019 Academic Article GET IT
Times cited: 6
Albumin-Binding PSMA Ligands: Implications for Expanding the Therapeutic Window. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 33
A Single Dose of ²²⁵Ac-RPS-074 Induces a Complete Tumor Response in an LNCaP Xenograft Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 45
⁶⁶Ga: A Novelty or a Valuable Preclinical Screening Tool for the Design of Targeted Radiopharmaceuticals?. Molecules (Basel, Switzerland). 2018 Academic Article GET IT
Times cited: 8
Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets. Journal of neuroinflammation. 2018 Academic Article GET IT
Times cited: 14
PSMA Ligand PET/MRI for Primary Prostate Cancer: Staging Performance and Clinical Impact. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 82
Targeting prostate cancer: Prostate-specific membrane antigen based diagnosis and therapy. Medicinal research reviews. 2018 Review GET IT
Times cited: 76
Trifunctional PSMA-targeting constructs for prostate cancer with unprecedented localization to LNCaP tumors. European journal of nuclear medicine and molecular imaging. 2018 Academic Article GET IT
Times cited: 48
[¹⁸F]RPS-544: A PET tracer for imaging the chemokine receptor CXCR4. Nuclear medicine and biology. 2018 Academic Article GET IT
Times cited: 10
Intraindividual Comparison of ^99mTc-Methylene Diphosphonate and Prostate-Specific Membrane Antigen Ligand ^99mTc-MIP-1427 in Patients with Osseous Metastasized Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 22
⁶⁸Ga-PSMA 11 ligand PET imaging in patients with biochemical recurrence after radical prostatectomy - diagnostic performance and impact on therapeutic decision-making. European journal of nuclear medicine and molecular imaging. 2017 Academic Article GET IT
Times cited: 80
An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angewandte Chemie (International ed. in English). 2017 Academic Article GET IT
Times cited: 117
Assessment of PSMA targeting ligands bearing novel chelates with application to theranostics: Stability and complexation kinetics of ⁶⁸Ga³⁺, ¹¹¹In³⁺, ¹⁷⁷Lu³⁺ and ²²⁵Ac³. Nuclear medicine and biology. 2017 Academic Article GET IT
Times cited: 19
Glu-Ureido-Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Review GET IT
Times cited: 92
Identification of Ligands and Translation to Clinical Applications. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Review GET IT
Times cited: 16
Continuation of comprehensive quality control of the itG ⁶⁸Ge/⁶⁸Ga generator and production of ⁶⁸Ga-DOTATOC and ⁶⁸Ga-PSMA-HBED-CC for clinical research studies. Nuclear medicine and biology. 2017 Academic Article GET IT
Times cited: 6
Dual-Target Binding Ligands with Modulated Pharmacokinetics for Endoradiotherapy of Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 56
Phase 2 Study of ^99mTc-Trofolastat SPECT/CT to Identify and Localize Prostate Cancer in Intermediate- and High-Risk Patients Undergoing Radical Prostatectomy and Extended Pelvic LN Dissection. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 52
Repeated PSMA-targeting radioligand therapy of metastatic prostate cancer with ¹³¹I-MIP-1095. European journal of nuclear medicine and molecular imaging. 2017 Academic Article GET IT
Times cited: 59
Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors. Scientific reports. 2017 Academic Article GET IT
Times cited: 13
Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75. Chirality. 2016 Academic Article GET IT
Times cited: 5
Longitudinal PET imaging demonstrates biphasic CAR T cell responses in survivors. JCI insight. 2016 Academic Article GET IT
Times cited: 59
Synthesis and pre-clinical evaluation of a new class of high-affinity ¹⁸F-labeled PSMA ligands for detection of prostate cancer by PET imaging. European journal of nuclear medicine and molecular imaging. 2016 Academic Article GET IT
Times cited: 43
The Rise of PSMA Ligands for Diagnosis and Therapy of Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Review GET IT
Times cited: 172
Preliminary evaluation of prostate-targeted radiotherapy using (131) I-MIP-1095 in combination with radiosensitising chemotherapeutic drugs. The Journal of pharmacy and pharmacology. 2016 Academic Article GET IT
Times cited: 19
Comprehensive Quality Control of the ITG 68Ge/68Ga Generator and Synthesis of 68Ga-DOTATOC and 68Ga-PSMA-HBED-CC for Clinical Imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 35
Prostaglandin J2: a potential target for halting inflammation-induced neurodegeneration. Annals of the New York Academy of Sciences. 2016 Review GET IT
Times cited: 23
New Strategies in Prostate Cancer: Prostate-Specific Membrane Antigen (PSMA) Ligands for Diagnosis and Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Review GET IT
Times cited: 127
Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy. Radiation research. 2015 Academic Article GET IT
Times cited: 28
Synthesis of [11C]palmitic acid for PET imaging using a single molecular sieve 13X cartridge for reagent trapping, radiolabeling and selective purification. Nuclear medicine and biology. 2015 Academic Article GET IT
Times cited: 6
PMPA for nephroprotection in PSMA-targeted radionuclide therapy of prostate cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2015 Academic Article GET IT
Times cited: 78
Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration. Frontiers in molecular neuroscience. 2015 Review GET IT
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: pharmacokinetics and biodistribution studies in healthy subjects and patients with metastatic prostate cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Academic Article GET IT
Times cited: 109
Phase-1 clinical trial results of high-specific-activity carrier-free 123I-iobenguane. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Academic Article GET IT
Times cited: 17
Radiation dosimetry and first therapy results with a (124)I/ (131)I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy. European journal of nuclear medicine and molecular imaging. 2014 Academic Article GET IT
Times cited: 280
Single amino acid chelate complexes of the M(CO)3 (+) core for correlating fluorescence and radioimaging studies (M = (99m) Tc or Re). Journal of labelled compounds & radiopharmaceuticals. 2014 Review GET IT
Times cited: 38
Is nano too big?. European journal of nuclear medicine and molecular imaging. 2014 Editorial Article GET IT
Times cited: 12
Radiopharmaceutical therapy of patients with metastasized melanoma with the melanin-binding benzamide 131I-BA52. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 48
Radiosensitization of noradrenaline transporter-expressing tumour cells by proteasome inhibitors and the role of reactive oxygen species. EJNMMI research. 2013 Academic Article GET IT
Times cited: 68
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 176
PSMA as a target for radiolabelled small molecules. European journal of nuclear medicine and molecular imaging. 2013 Editorial Article GET IT
Times cited: 116
The role of copper in disulfiram-induced toxicity and radiosensitization of cancer cells. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 56
Gamma irradiation and targeted radionuclides enhance the expression of the noradrenaline transporter transgene controlled by the radio-inducible p21(WAF1/CIP1) promoter. Radiation research. 2013 Academic Article GET IT
Times cited: 3
First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 171
Synthesis and SAR of novel Re/99mTc-labeled benzenesulfonamide carbonic anhydrase IX inhibitors for molecular imaging of tumor hypoxia. Journal of medicinal chemistry. 2013 Academic Article GET IT
Times cited: 34
Synthesis and SAR of ⁹⁹mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates. Bioorganic & medicinal chemistry letters. 2012 Academic Article GET IT
Times cited: 76
Dose escalation study of no-carrier-added 131I-metaiodobenzylguanidine for relapsed or refractory neuroblastoma: new approaches to neuroblastoma therapy consortium trial. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2012 Academic Article GET IT
Times cited: 56
Inhibition of poly(ADP-Ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2012 Academic Article GET IT
Times cited: 21
Molecular imaging of human ACE-1 expression in transgenic rats. JACC. Cardiovascular imaging. 2012 Academic Article GET IT
Times cited: 35
Triazole Appending Agent (TAAG): A New Synthon for Preparing Iodine-Based Molecular Imaging and Radiotherapy Agents. ACS medicinal chemistry letters. 2012 Academic Article GET IT
Times cited: 21
123I-MIP-1072, a small-molecule inhibitor of prostate-specific membrane antigen, is effective at monitoring tumor response to taxane therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011 Academic Article GET IT
Times cited: 66
Diagnostic and therapeutic imaging for cancer: therapeutic considerations and future directions. Journal of surgical oncology. 2011 Review GET IT
Times cited: 17
Synthesis, cytotoxicity and cellular uptake studies of N3 functionalized Re(CO)3 thymidine complexes. Dalton transactions (Cambridge, England : 2003). 2011 Academic Article GET IT
Times cited: 34
Phase I trial of 90Y-DOTATOC therapy in children and young adults with refractory solid tumors that express somatostatin receptors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010 Academic Article GET IT
Times cited: 65
Synthesis, cytotoxicity, and insight into the mode of action of Re(CO)3 thymidine complexes. ChemMedChem. 2010 Academic Article GET IT
Times cited: 39
Iodofiltic acid I 123 (BMIPP) fatty acid imaging improves initial diagnosis in emergency department patients with suspected acute coronary syndromes: a multicenter trial. Journal of the American College of Cardiology. 2010 Academic Article GET IT
Times cited: 54
Novel polar single amino acid chelates for technetium-99m tricarbonyl-based radiopharmaceuticals with enhanced renal clearance: application to octreotide. Bioconjugate chemistry. 2010 Academic Article GET IT
Times cited: 58
Comparison of high-specific-activity ultratrace 123/131I-MIBG and carrier-added 123/131I-MIBG on efficacy, pharmacokinetics, and tissue distribution. Cancer biotherapy & radiopharmaceuticals. 2010 Academic Article GET IT
Times cited: 58
Preclinical evaluation of an 131I-labeled benzamide for targeted radiotherapy of metastatic melanoma. Cancer research. 2010 Academic Article GET IT
Times cited: 44
Synthesis and characterization of rhenium and technetium-99m labeled insulin. Journal of medicinal chemistry. 2010 Academic Article GET IT
Times cited: 28
Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer. Cancer research. 2009 Academic Article GET IT
Times cited: 255
Radiation dosimetry, pharmacokinetics, and safety of ultratrace Iobenguane I-131 in patients with malignant pheochromocytoma/paraganglioma or metastatic carcinoid. Cancer biotherapy & radiopharmaceuticals. 2009 Academic Article GET IT
Times cited: 49
Comprehensive radiolabeling, stability, and tissue distribution studies of technetium-99m single amino acid chelates (SAAC). Bioconjugate chemistry. 2009 Academic Article GET IT
Times cited: 44
A series of halogenated heterodimeric inhibitors of prostate specific membrane antigen (PSMA) as radiolabeled probes for targeting prostate cancer. Journal of medicinal chemistry. 2009 Academic Article GET IT
Times cited: 231
Radiohalogenated prostate-specific membrane antigen (PSMA)-based ureas as imaging agents for prostate cancer. Journal of medicinal chemistry. 2008 Academic Article GET IT
Times cited: 168
Single amino acid chelates (SAAC): a strategy for the design of technetium and rhenium radiopharmaceuticals. Chemical communications (Cambridge, England). 2008 Review GET IT
Times cited: 165
Experimental treatment of neuroblastoma using [131I]meta-iodobenzylguanidine and topotecan in combination. The British journal of radiology. 2008 Academic Article GET IT
Times cited: 27
A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents. Chemical communications (Cambridge, England). 2008 Academic Article GET IT
Times cited: 20
Synthesis and evaluation of a series of 99mTc(CO)3+ lisinopril complexes for in vivo imaging of angiotensin-converting enzyme expression. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 Academic Article GET IT
Times cited: 32
Synthesis and screening of a library of Re/Tc-based amyloid probes derived from beta-breaker peptides. Bioconjugate chemistry. 2008 Academic Article GET IT
Times cited: 27
Isostructural fluorescent and radioactive probes for monitoring neural stem and progenitor cell transplants. Nuclear medicine and biology. 2008 Academic Article GET IT
Times cited: 43
A kit method for the high level synthesis of [211At]MABG. Bioorganic & medicinal chemistry. 2007 Academic Article GET IT
Times cited: 47
Future directions of myocardial fatty acid imaging. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 2007 Review GET IT
Times cited: 7
Synthesis and validation of fatty acid analogs radiolabeled by nonisotopic substitution. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 2007 Review GET IT
Times cited: 16
Developing the {M(CO)3}+ core for fluorescence applications: Rhenium tricarbonyl core complexes with benzimidazole, quinoline, and tryptophan derivatives. Inorganic chemistry. 2006 Academic Article GET IT
Times cited: 78
A new strategy for preparing molecular imaging and therapy agents using fluorine-rich (fluorous) soluble supports. Journal of the American Chemical Society. 2006 Academic Article GET IT
Times cited: 42
Extension of the single amino acid chelate concept (SAAC) to bifunctional biotin analogues for complexation of the M(CO)3(+1) Core (M = Tc and Re): syntheses, characterization, biotinidase stability, and avidin binding. Bioconjugate chemistry. 2006 Academic Article GET IT
Times cited: 46
Isostructural Re and 99mTc complexes of biotin derivatives for fluorescence and radioimaging studies. Bioconjugate chemistry. 2006 Academic Article GET IT
Times cited: 62
Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene- and targeted radiotherapy approach to bladder carcinoma. Medicinal chemistry (Shariqah (United Arab Emirates)). 2005 Academic Article GET IT
Times cited: 10
Metabolic imaging with beta-methyl-p-[(123)I]-iodophenyl-pentadecanoic acid identifies ischemic memory after demand ischemia. Circulation. 2005 Academic Article GET IT
Times cited: 164
Thiol- and thioether-based bifunctional chelates for the {M(CO)3}+ core (M = Tc, Re). Inorganic chemistry. 2005 Academic Article GET IT
Times cited: 59
Design and synthesis of site directed maleimide bifunctional chelators for technetium and rhenium. Dalton transactions (Cambridge, England : 2003). 2005 Academic Article GET IT
Times cited: 43
Rhenium tricarbonyl core complexes of thymidine and uridine derivatives. Inorganic chemistry. 2005 Academic Article GET IT
Times cited: 60
Site directed maleimide bifunctional chelators for the M(CO)3+ core (M =(99m)Tc, Re). Chemical communications (Cambridge, England). 2005 Academic Article GET IT
Times cited: 35
A new strategy for the preparation of peptide-targeted technetium and rhenium radiopharmaceuticals. The automated solid-phase synthesis, characterization, labeling, and screening of a peptide-ligand library targeted at the formyl peptide receptor. Bioconjugate chemistry. 2005 Academic Article GET IT
Times cited: 25
N,N-bis(2-mercaptoethyl)methylamine: a new coligand for Tc-99m labeling of hydrazinonicotinamide peptides. Bioconjugate chemistry. 2005 Academic Article GET IT
Times cited: 18
New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design. Nuclear medicine and biology. 2005 Review GET IT
Times cited: 167
Unusual reactivity of the [Re(V)O]3+ core: syntheses and characterization of novel rhenium halide complexes with n-methyl-o-diaminobenzene. Inorganic chemistry. 2004 Academic Article GET IT
Times cited: 27
Bridging the gap between in vitro and in vivo imaging: isostructural Re and 99mTc complexes for correlating fluorescence and radioimaging studies. Journal of the American Chemical Society. 2004 Academic Article GET IT
Times cited: 185
A new strategy for the preparation of peptide-targeted radiopharmaceuticals based on an fmoc-lysine-derived single amino acid chelate (SAAC). automated solid-phase synthesis, NMR characterization, and in vitro screening of fMLF(SAAC)G and fMLF[(SAAC-Re(CO)3)+]G. Bioconjugate chemistry. 2004 Academic Article GET IT
Times cited: 111
Bifunctional single amino acid chelates for labeling of biomolecules with the [Tc(CO)(3)](+) and [Re(CO)(3)](+) cores. Crystal and molecular structures of [ReBr(CO)(3)(H(2)NCH(2)C(5)H(4)N)], [Re(CO)(3)[(C(5)H(4)NCH(2))(2)NH]]Br, [Re(CO)(3)[(C(5)H(4)NCH(2))(2)NCH(2)CO(2)H]]Br, [Re(CO)(3)[X(Y)NCH(2)CO(2)CH(2)CH(3)]]Br (X = Y = 2-pyridylmethyl; X = 2-pyridylmethyl, Y = 2-(1-methylimidazolyl)methyl; X = Y = 2-(1-methylimidazolyl)methyl), [ReBr(CO)(3)[(C(5)H(4)NCH(2))NH(CH(2)C(4)H(3)S)]], and [Re(CO)(3)[(C(5)H(4)NCH(2))N(CH(2)C(4)H(3)S)(CH(2)CO(2))]]. Inorganic chemistry. 2002 Academic Article GET IT
Times cited: 167
[Re(III)Cl(3)] core complexes with bifunctional single amino acid chelates. Inorganic chemistry. 2002 Academic Article GET IT
Times cited: 20
Mapping of local renal blood flow with PET and H(2)(15)O. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2002 Academic Article GET IT
Times cited: 40
Rhenium(I) carbonyl complexes of 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPT). Rhenium(I)-promoted methoxylation of the triazine ring carbon atom in dinuclear rhenium complexes. Inorganic chemistry. 2001 Academic Article GET IT
Times cited: 51
Schiff base chemistry of the rhenium(V)-oxo core with '3+2' ligand donor sets. Inorganica chimica acta. 2001 Academic Article GET IT
Times cited: 22
Synthesis and structural characterization of rhenium(I) tricarbonyl complexes with the bidentate ligands o-(diphenylphosphino)benzaldehyde (P∩O) and o-[(diphenylphosphino)benzylidene]analine (P∩N). Inorganica chimica acta. 2001 Academic Article GET IT
Times cited: 45
Synthesis, characterization and crystal structures of mono-, di- and trinuclear rhenium(I) tricarbonyl complexes with 2,3,5,6-tetra(2-pyridyl)pyrazine. Inorganica chimica acta. 2001 Academic Article GET IT
Times cited: 32
[(11)C, (127)I] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites. Synapse (New York, N.Y.). 2001 Academic Article GET IT
Times cited: 59
Novel monoamine transporter ligands reduce cocaine-induced enhancement of brain stimulation reward. Pharmacology, biochemistry, and behavior. 2001 Academic Article GET IT
Times cited: 3
An unexpected '4+2' [N(3)S]:[NS] rhenium(IV) complex formed upon cleavage of a Re(V) imido bond. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 3
Syntheses and structural characterization of rhenium-bis-hydrazinopyrimidine core complexes with thiolate and Schiff base coligands. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 9
The syntheses and structures of '3+2' and '2+2+1' oxorhenium mixed-ligand complexes employing 8-hydroxy-5-nitroquinoline as the bidentate N,O donor ligand. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 55
Long-circulating gadolinium-loaded liposomes: potential use for magnetic resonance imaging of the blood pool. Colloids and surfaces. B, Biointerfaces. 2000 Academic Article GET IT
Times cited: 67
Exploring oxorhenium '3+1' mixed-ligand complexes carrying the S-benzyl-3-[(2-hydroxyphenyl)methylene]dithiocarbazate [ONS]/monothiol [S] donor set: synthesis and characterization. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 26
Schiff base chemistry of the {ReO} core: structural characterization of the unusual '3 + 2' complex [ReO(eta-OC(6)H(4)-CH=NC(6)H(4)-2-S)(eta-OC(6)H(4))]. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 31
Synthesis and characterization of oxorhenium(V)-'3+1' mixed thiolate [SNS]/[S] and [ONS]/[S] complexes. Crystal and molecular structures of [ReO(eta-SCH(2)C(5)H(3)NCH(2)S)(eta-C(6)H(4)Br-4-S)], [ReO(eta-SCH(2)C(5)H(3)NCH(2)O)(eta-C(6)H(4)X-4-S)] (X=Cl, OMe), [ReO(eta-SCH(2)C(5)H(3)NCH(2)O)(eta-C(6)H(4)OCH(3)-4-CH(2)S)] and [ReO(eta-SCH(2)C(5)H(3)NCH(2)S)(eta-C(5)H(4)NH-2-S)][Cl]. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 20
Synthesis and crystal and molecular structure of a tetranuclear cluster based on the rhenium(III)-bisorganohydrazino core: [Re(HNNC(4)H(3)N(2))(NNC(4)H(3)N(2))(OCH(3))(2)](4). Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 7
Investigations of the {ReO} core: A '2+2' complex from bidentate and potentially trident ligands: [ReO(η-HOC(6)H(4)-2-CH(2)NC(6)H(4)S)(η-SC(5)H(4)N)(PPh(3))]. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 8
Structural characterizations of an Re(IV) complex [ReCl(4)(OPPh(3))(2)] and of an imino species [ReOCl(2)(PPh(3))(eta-OC(6)H(4)-2-CH=NH)] prepared from the reaction of [ReOCl(3)(PPh(3))(2)] with salicylaldoxime. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 9
Synthesis and characterization of complexes of the {ReO} core with SNS and S donor ligands. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 21
Oxorhenium(V) complexes containing tridentate Schiff-base and monothiol coligands. Inorganica chimica acta. 2000 Academic Article GET IT
Times cited: 18
Synthesis and biological evaluation of two novel DAT-binding technetium complexes containing a piperidine based analogue of cocaine. Bioorganic & medicinal chemistry letters. 1999 Academic Article GET IT
Times cited: 15
Targeted imaging of infection. Advanced drug delivery reviews. 1999 Academic Article GET IT
Times cited: 7
Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules. Proceedings of the National Academy of Sciences of the United States of America. 1999 Academic Article GET IT
Times cited: 177
Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans. Proceedings of the National Academy of Sciences of the United States of America. 1998 Academic Article GET IT
Times cited: 28
Pharmacokinetics of [18F]trovafloxacin in healthy human subjects studied with positron emission tomography. Antimicrobial agents and chemotherapy. 1998 Academic Article GET IT
Times cited: 50
Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain. Synapse (New York, N.Y.). 1998 Academic Article GET IT
Times cited: 39
Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain. Synapse (New York, N.Y.). 1998 Academic Article GET IT
Times cited: 60
Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters. Synapse (New York, N.Y.). 1998 Academic Article GET IT
Times cited: 120
Synthesis and Characterization of Organohydrazino Complexes of Technetium, Rhenium, and Molybdenum with the {M(eta(1)-H(x)()NNR)(eta(2)-H(y)()NNR)} Core and Their Relationship to Radiolabeled Organohydrazine-Derivatized Chemotactic Peptides with Diagnostic Applications. Inorganic chemistry. 1998 Academic Article GET IT
Times cited: 89
Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates. Proceedings of the National Academy of Sciences of the United States of America. 1998 Academic Article GET IT
Times cited: 45
Positron emission tomographic analysis of central dopamine D1 receptor binding in normal subjects treated with the atypical neuroleptic, SDZ MAR 327. International journal of molecular medicine. 1998 Academic Article GET IT
Times cited: 5
The role of positron emission tomography in pharmacokinetic analysis. Drug metabolism reviews. 1997 Review GET IT
Times cited: 64
Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1997 Academic Article GET IT
Times cited: 49
Pharmacokinetics of 18F-labeled trovafloxacin in normal and Escherichia coli-infected rats and rabbits studied with positron emission tomography. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1997 Academic Article GET IT
Effect of adrenergic receptor ligands on metaiodobenzylguanidine uptake and storage in neuroblastoma cells. European journal of nuclear medicine. 1997 Academic Article GET IT
Times cited: 20
Pharmacokinetics of 18F-labeled trovafloxacin in normal and Escherichia coli-infected rats and rabbits studied with positron emission tomography. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1997 Academic Article GET IT
Times cited: 21
SPECT imaging of dopamine transporter sites in normal and MPTP-Treated rhesus monkeys. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1997 Academic Article GET IT
Times cited: 35
18F-labeling and biodistribution of the novel fluoro-quinolone antimicrobial agent, trovafloxacin (CP 99,219). Nuclear medicine and biology. 1996 Academic Article GET IT
Times cited: 26
Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone. The Journal of pharmacology and experimental therapeutics. 1996 Academic Article GET IT
Times cited: 70
Quantification of dopamine transporter density in monkeys by dynamic PET imaging of multiple injections of 11C-CFT. Synapse (New York, N.Y.). 1996 Academic Article GET IT
Times cited: 36
Evaluation of cerebral pharmacokinetics of the novel antidepressant drug, BMS-181101, by positron emission tomography. The Journal of pharmacology and experimental therapeutics. 1996 Academic Article GET IT
Times cited: 32
Evaluation of phenylpiperazines as targeting agents for neuroblastoma. British journal of cancer. 1996 Academic Article GET IT
Times cited: 4
Thermal injury in rats alters glucose utilization by skin, wound, and small intestine, but not by skeletal muscle. Metabolism: clinical and experimental. 1996 Academic Article GET IT
Times cited: 25
Decreased cerebral glucose utilization in rats during the ebb phase of thermal injury. The Journal of trauma. 1996 Academic Article GET IT
Times cited: 17
Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 20
Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography. Antimicrobial agents and chemotherapy. 1996 Academic Article GET IT
Times cited: 33
Comparison of the infection imaging properties of a 99mTc labeled chemotactic peptide with 111In IgG. Nuclear medicine and biology. 1995 Academic Article GET IT
Times cited: 48
Detection of acute bacterial infection within soft tissue injuries using a 99mTc-labeled chemotactic peptide. The Journal of trauma. 1995 Academic Article GET IT
Times cited: 10
Effect of "co-ligand" on the biodistribution of 99mTc-labeled hydrazino nicotinic acid derivatized chemotactic peptides. Nuclear medicine and biology. 1995 Academic Article GET IT
Times cited: 116
Synthesis of a 11C-labeled NK1 receptor ligand for PET studies. Nuclear medicine and biology. 1995 Academic Article GET IT
Times cited: 13
Tissue blood flow estimation with copper(II)-pyruvaldehyde bis (N-4-methylthiosemicarbazone) and PET. Journal of nuclear biology and medicine (Turin, Italy : 1991). 1994 Academic Article GET IT
Times cited: 14
Synthesis of fluorine-18-labeled biotin derivatives: biodistribution and infection localization. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1994 Academic Article GET IT
Times cited: 46
The dose uptake ratio as an index of glucose metabolism: useful parameter or oversimplification?. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1994 Academic Article GET IT
Times cited: 382
Tissue pharmacokinetics of fleroxacin in humans as determined by positron emission tomography. International journal of antimicrobial agents. 1994 Academic Article GET IT
Times cited: 5
Synthesis of 2-[18F]fluoro-2-deoxy-L-glucose and positron emission tomography studies in monkeys. Nuclear medicine and biology. 1994 Academic Article GET IT
Times cited: 2
Synthesis of [11C]dapoxetine.HCl, a serotonin re-uptake inhibitor: biodistribution in rat and preliminary PET imaging in the monkey. Nuclear medicine and biology. 1994 Academic Article GET IT
Times cited: 24
Evaluation of copper(II)-pyruvaldehyde bis (N-4-methylthiosemicarbazone) for tissue blood flow measurement using a trapped tracer model. European journal of nuclear medicine. 1994 Academic Article GET IT
Times cited: 47
Infection imaging with technetium-99m-labeled chemotactic peptide analogs. Seminars in nuclear medicine. 1994 Academic Article GET IT
Times cited: 62
Imaging of focal sites of inflammation in rhesus monkeys with 99mTc-labeled human polyclonal IgG. Nuclear medicine and biology. 1994 Academic Article GET IT
Times cited: 10
A ticket to ride: peptide radiopharmaceuticals. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Review GET IT
Times cited: 198
In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 81
Technetium-99m-labeled chemotactic peptides: comparison with indium-111-labeled white blood cells for localizing acute bacterial infection in the rabbit. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 88
Localization of indium-111-immunoglobulin G, technetium-99m-immunoglobulin G and indium-111-labeled white blood cells at sites of acute bacterial infection in rabbits. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 26
Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 140
Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography. Antimicrobial agents and chemotherapy. 1993 Academic Article GET IT
Times cited: 47
Myocardial substrate utilization and left ventricular function in adriamycin cardiomyopathy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 51
Metaiodobenzylguanidine: evaluation of its potential as a tracer for monitoring doxorubicin cardiomyopathy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Academic Article GET IT
Times cited: 67
Pharmacokinetics of fleroxacin as studied by positron emission tomography and [18F]fleroxacin. The American journal of medicine. 1993 Academic Article GET IT
Times cited: 7
Synthesis and biodistribution of 18F-labeled fleroxacin. Nuclear medicine and biology. 1993 Academic Article GET IT
Times cited: 17
c-erbB2 protein overexpression in breast cancer as a target for PET using iodine-124-labeled monoclonal antibodies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1992 Academic Article GET IT
Times cited: 72
Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography. Antimicrobial agents and chemotherapy. 1992 Academic Article GET IT
Times cited: 32
Treatment planning for 131I-mIBG radiotherapy of neural crest tumours using 124I-mIBG positron emission tomography. The British journal of radiology. 1992 Academic Article GET IT
Times cited: 69
Preoperative imaging of colorectal cancers. Targeting the epithelial membrane antigen with a radiation-labeled monoclonal antibody. Cancer. 1992 Academic Article GET IT
Times cited: 11
Development of a high performance zinc-62/copper-62 radionuclide generator for positron emission tomography. European journal of nuclear medicine. 1992 Academic Article GET IT
Times cited: 33
The effect of circulating antigen and radiolabel stability on the biodistribution of an indium labelled antibody. British journal of cancer. 1991 Academic Article GET IT
Times cited: 13
Technetium-99m-HMPAO retention and the role of glutathione: the debate continues. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1991 Editorial Article GET IT
Times cited: 19
Implications of the uptake of 131I-radiolabelled meta-iodobenzylguanidine (mIBG) for the targeted radiotherapy of neuroblastoma. The British journal of radiology. 1991 Academic Article GET IT
Times cited: 20
The distribution of alternative agents for targeted radiotherapy within human neuroblastoma spheroids. British journal of cancer. 1991 Academic Article GET IT
Times cited: 21
Differential penetration of targeting agents into multicellular spheroids derived from human neuroblastoma. Progress in clinical and biological research. 1991 Academic Article GET IT
Times cited: 13
Measurements of blood-brain barrier permeability in patients undergoing radiotherapy and chemotherapy for primary cerebral lymphoma. 1991 GET IT
Times cited: 98
Therapeutic implications of the uptake of radiolabelled mIBG for the treatment of neuroblastoma. Progress in clinical and biological research. 1991 Academic Article GET IT
Times cited: 4
Quantitative in vivo measurements of tumor perfusion using rubidium-81 and positron emission tomography. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1990 Academic Article GET IT
Times cited: 20
An evaluation of 99mTc-HMPAO uptake in cerebral gliomas--a comparison with X-ray CT. European journal of nuclear medicine. 1990 Academic Article GET IT
Times cited: 11
The future of PET. Nuclear medicine communications. 1989 Editorial Article GET IT
Times cited: 5
Quantitative study of radioiodinated metaiodobenzylguanidine uptake in children with neuroblastoma: correlation with tumor histopathology. 1989 GET IT
Times cited: 38
Image quantification with a large area multiwire proportional chamber positron camera (MUP-PET). European journal of nuclear medicine. 1989 Academic Article GET IT
Times cited: 12
An improved tungsten-178/tantalum-178 generator system for high volume clinical applications. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1988 Academic Article GET IT
Times cited: 16
Initial experience with Tc-99m-HM-PAO in the study of brain tumors. European journal of nuclear medicine. 1988 Academic Article GET IT
Times cited: 23
The biodistribution and pharmacokinetics of meta-iodobenzylguanidine in childhood neuroblastoma. European journal of nuclear medicine. 1988 Academic Article GET IT
Times cited: 30
Failure of iodine-131 MIBG imaging in small cell lung carcinoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1987 Letter GET IT
Times cited: 5
99mTc-HMPAO as a tumour blood flow agent. European journal of nuclear medicine. 1987 Academic Article GET IT
Times cited: 30
An antibody-desferrioxamine conjugate labelled with 67Ga. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 1986 Academic Article GET IT
Times cited: 5
A gamma camera for medical applications, using a multiwire proportional counter. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1984 Academic Article GET IT
Times cited: 22

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Research

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Co-investigator Network

Funding awarded

Perimenopause in Brain Aging and Alzheimer''s disease awarded by National Institute on Aging Co-Investigator 2021 - 2026
PSMA/MR-guided Stereotactic Body Radiotherapy for High Risk Prostate Cancer awarded by National Cancer Institute Co-Investigator 2020 - 2024
The Development of Radiolabeled Positional isomers of [11C]Pyruvate for Imaging Cancer Metabolism awarded by National Institute of Biomedical Imaging & Bioengineering Co-Investigator 2020 - 2024
CSF Clearance in Sporadic Alzheimer''s Disease awarded by National Institute on Aging Co-Investigator 2019 - 2024
Rapid Noninvasive Whole-body Imaging of AAV Gene Transfer Vectors awarded by National Institute of Biomedical Imaging & Bioengineering Co-Investigator 2019 - 2024
Sex Differences in the Molecular Determinants of Alzheimer''s Disease Risk: Prodromal Endophenotype awarded by National Institute on Aging Co-Investigator 2019 - 2023
Identifying mechanisms of tissue injury in MS lesions: a multi-modality imaging approach awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2018 - 2023
Predictive Model of Spread of Parkinson''s Pathology Using Network Diffusion awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2016 - 2023

Sex Differences in the Molecular Determinants of Alzheimer’s Disease Risk awarded by National Institute on Aging Key Personnel 2018 - 2024
Major Cyclotron Upgrades and Refurbishment awarded by National Institutes of Health, Office of the Director Key Personnel 2021 - 2023
Impact of Aortic Wall Inflammation and Stiffness on Thoracic Aortic Growth in Marfan Syndrome awarded by National Heart, Lung, & Blood Institute Key Personnel 2017 - 2023

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Background

education and training

Ph.D., University of London (United Kingdom) 1994
M.S., University of Southern California 1981
B.S., St. John's University 1980

Contact

full name

John Babich

primary email

job2060@med.cornell.edu

VIVO Weill Cornell Medical College

John Babich Professor of Radiopharmaceutical Sciences in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email