selected publications
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Biology of antimicrobial resistance and approaches to combat it.
Science translational medicine.
2020
Review
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Times cited: 70 -
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
Science (New York, N.Y.).
2019
Academic Article
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Times cited: 46 - Building Walls: Work That Never Ends. Trends in microbiology. 2018 Comment GET IT
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Targeting the Proteostasis Network for Mycobacterial Drug Discovery.
ACS infectious diseases.
2018
Review
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Times cited: 43 -
Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.
mBio.
2017
Academic Article
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Times cited: 33 -
Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.
Nature communications.
2017
Academic Article
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Times cited: 42 -
Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress.
The EMBO journal.
2017
Academic Article
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Times cited: 32 -
Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.
PLoS pathogens.
2015
Academic Article
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Times cited: 26 -
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.
Cell host & microbe.
2015
Academic Article
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Times cited: 70 -
N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
Journal of the American Chemical Society.
2013
Academic Article
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Times cited: 44 -
A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
The Journal of biological chemistry.
2012
Academic Article
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Times cited: 78 -
Deciphering sulfoglycolipids of Mycobacterium tuberculosis.
Journal of lipid research.
2011
Academic Article
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Times cited: 37 -
Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ.
Microbiology (Reading, England).
2010
Academic Article
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Times cited: 25 -
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.
The Journal of biological chemistry.
2009
Academic Article
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Times cited: 24 -
Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence.
PLoS pathogens.
2008
Academic Article
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Times cited: 523