selected publications
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Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non-Muscle-Invasive Bladder Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2022
Academic Article
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Times cited: 3 -
Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult brain tumor patients.
Neuro-oncology.
2022
Academic Article
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Times cited: 15 -
Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2022
Academic Article
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Times cited: 3 - Matched Molecular Profiling of Cell-Free DNA and Tumor Tissue in Patients With Advanced Clear Cell Renal Cell Carcinoma. JCO precision oncology. 2022 Academic Article GET IT
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The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2022
Academic Article
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Times cited: 3 -
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets.
Science (New York, N.Y.).
2022
Academic Article
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Times cited: 22 - Evaluation of TERT mRNA expression using RNAscope®: A potential histopathologic diagnostic and prognostic tool. Pathology, research and practice. 2022 Academic Article GET IT
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Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2022
Academic Article
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Times cited: 3 - Author Correction: The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers. Nature communications. 2022 Article GET IT
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Cancer-Causative Mutations Occurring in Early Embryogenesis.
Cancer discovery.
2022
Academic Article
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Times cited: 9 -
Defining Novel DNA Virus-Tumor Associations and Genomic Correlates Using Prospective Clinical Tumor/Normal Matched Sequencing Data.
The Journal of molecular diagnostics : JMD.
2022
Academic Article
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Times cited: 3 -
The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.
Nature communications.
2022
Academic Article
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Times cited: 23 -
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.
Cell.
2022
Academic Article
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Times cited: 86 -
Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2022
Academic Article
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Times cited: 8 -
A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers.
Journal of the National Cancer Institute.
2021
Academic Article
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Times cited: 32 -
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights.
Nature communications.
2021
Academic Article
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Times cited: 7 -
Multiple Primary Cancers in Patients Undergoing Tumor-Normal Sequencing Define Novel Associations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2021
Comment
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Times cited: 5 -
Diverse alterations associated with resistance to KRAS(G12C) inhibition.
Nature.
2021
Academic Article
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Times cited: 88 -
The context-specific role of germline pathogenicity in tumorigenesis.
Nature genetics.
2021
Academic Article
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Times cited: 29 -
Association of Plasma Circulating Tumor DNA With Diagnosis of Metastatic Uveal Melanoma.
JAMA ophthalmology.
2021
Academic Article
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Times cited: 3 -
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types.
Nature biotechnology.
2021
Academic Article
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Times cited: 58 -
Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021
Comment
GET IT
Times cited: 18 -
Clonal hematopoiesis is associated with risk of severe Covid-19.
Nature communications.
2021
Academic Article
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Times cited: 38 - Corrigendum to "Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions" [Lung Cancer 159 (2021) 66-73]. Lung cancer (Amsterdam, Netherlands). 2021 Article GET IT
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A quick guide for clinical oncology.
Nature cancer.
2021
Comment
GET IT
Times cited: 1 - TERT Copy Number Alterations, Promoter Mutations and Rearrangements in Adrenocortical Carcinomas. Endocrine pathology. 2021 Academic Article GET IT
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Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies.
NPJ breast cancer.
2021
Academic Article
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Times cited: 176 -
Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.
Cancer.
2021
Academic Article
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Times cited: 14 -
Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions.
Lung cancer (Amsterdam, Netherlands).
2021
Academic Article
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Times cited: 12 -
Resource-efficient pooled sequencing expands translational impact in solid tumors.
Kidney cancer journal : official journal of the Kidney Cancer Association.
2021
Academic Article
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Times cited: 5090 -
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS.
Nature communications.
2021
Academic Article
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Times cited: 42 -
Therapeutic Implications of Germline Testing in Patients With Advanced Cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2021
Academic Article
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Times cited: 37 - Erratum to 'Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group': [Annals of Oncology 30 (2019) 1221-1231]. Annals of oncology : official journal of the European Society for Medical Oncology. 2021 Article GET IT
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Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients.
Genome medicine.
2021
Academic Article
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Times cited: 14 -
Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase.
JAMA oncology.
2021
Academic Article
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Times cited: 86 -
Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA.
Nature metabolism.
2021
Academic Article
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Times cited: 35 -
Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021
Academic Article
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Times cited: 4 -
Clinical Experience of Cerebrospinal Fluid-Based Liquid Biopsy Demonstrates Superiority of Cell-Free DNA over Cell Pellet Genomic DNA for Molecular Profiling.
The Journal of molecular diagnostics : JMD.
2021
Academic Article
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Times cited: 8 -
Prevalence and Characterization of Biallelic and Monoallelic NTHL1 and MSH3 Variant Carriers From a Pan-Cancer Patient Population.
JCO precision oncology.
2021
Academic Article
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Times cited: 7 -
Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors.
Nature cancer.
2021
Academic Article
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Times cited: 48 -
A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.
JAMA surgery.
2021
Academic Article
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Times cited: 35 -
OncoTree: A Cancer Classification System for Precision Oncology.
JCO clinical cancer informatics.
2021
Academic Article
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Times cited: 22 -
Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors.
Nature communications.
2021
Academic Article
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Times cited: 117 -
Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis.
Nature communications.
2021
Academic Article
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Times cited: 37 -
Noninvasive Detection of Polyclonal Acquired Resistance to FGFR Inhibition in Patients With Cholangiocarcinoma Harboring FGFR2 Alterations.
JCO precision oncology.
2021
Academic Article
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Times cited: 19 -
Utility of Serial cfDNA NGS for Prospective Genomic Analysis of Patients on a Phase I Basket Study.
JCO precision oncology.
2021
Academic Article
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Times cited: 3 -
Molecular Changes in Retinoblastoma beyond RB1: Findings from Next-Generation Sequencing.
Cancers.
2021
Academic Article
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Times cited: 24 -
The association between tumor mutational burden and prognosis is dependent on treatment context.
Nature genetics.
2021
Academic Article
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Times cited: 87 -
A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled by Clinical Genomic Sequencing.
The Journal of molecular diagnostics : JMD.
2020
Academic Article
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Times cited: 12 -
Correction to: Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Annals of surgical oncology.
2020
Article
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Times cited: 1 -
Characterization and Clinical Outcomes of DNA Mismatch Repair-deficient Small Bowel Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020
Academic Article
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Times cited: 19 -
Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020
Comment
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Times cited: 9 -
Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs.
JCO precision oncology.
2020
Academic Article
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Times cited: 1209 -
Cancer therapy shapes the fitness landscape of clonal hematopoiesis.
Nature genetics.
2020
Academic Article
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Times cited: 221 -
TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors.
Cancer discovery.
2020
Academic Article
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Times cited: 20 -
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell.
2020
Academic Article
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Times cited: 477 -
A phase 2 trial of buparlisib in patients with platinum-resistant metastatic urothelial carcinoma.
Cancer.
2020
Academic Article
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Times cited: 10 -
Molecular profiling and analysis of genetic aberrations aimed at identifying potential therapeutic targets in fibrolamellar carcinoma of the liver.
Cancer.
2020
Academic Article
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Times cited: 3 -
Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer.
Cancer research.
2020
Comment
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Times cited: 13 -
Cell-free DNA profiling in retinoblastoma patients with advanced intraocular disease: An MSKCC experience.
Cancer medicine.
2020
Academic Article
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Times cited: 30 -
Developing Quality Programs for Cell-Free DNA (cfDNA) Extraction from Peripheral Blood.
The journal of applied laboratory medicine.
2020
Academic Article
GET IT
Times cited: 5 -
Effect of Osimertinib and Bevacizumab on Progression-Free Survival for Patients With Metastatic EGFR-Mutant Lung Cancers: A Phase 1/2 Single-Group Open-Label Trial.
JAMA oncology.
2020
Academic Article
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Times cited: 80 -
Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma.
Cancer.
2020
Academic Article
GET IT
Times cited: 31 -
Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020
Academic Article
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Times cited: 94 -
Protein-altering germline mutations implicate novel genes related to lung cancer development.
Nature communications.
2020
Academic Article
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Times cited: 18 -
Fragment Size Analysis May Distinguish Clonal Hematopoiesis from Tumor-Derived Mutations in Cell-Free DNA.
Clinical chemistry.
2020
Letter
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Times cited: 23 -
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers.
Cancer discovery.
2020
Academic Article
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Times cited: 100 -
Germline alterations in patients with biliary tract cancers: A spectrum of significant and previously underappreciated findings.
Cancer.
2020
Academic Article
GET IT
Times cited: 20 -
The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic.
Hematology/oncology clinics of North America.
2020
Review
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Times cited: 32 - Author Correction: Tumour lineage shapes BRCA-mediated phenotypes. Nature. 2020 Academic Article GET IT
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Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care.
JAMA oncology.
2020
Academic Article
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Times cited: 49 -
Cancer Susceptibility Mutations in Patients With Urothelial Malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2019
Academic Article
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Times cited: 47 -
Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms.
Nature medicine.
2019
Academic Article
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Times cited: 87 -
Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 49 -
PD-1 Blockade in Advanced Adrenocortical Carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2019
Academic Article
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Times cited: 91 -
Genomic Characterization of ERBB2-Driven Biliary Cancer and a Case of Response to Ado-Trastuzumab Emtansine.
JCO precision oncology.
2019
Academic Article
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Times cited: 25 -
Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 40 -
A rectal cancer organoid platform to study individual responses to chemoradiation.
Nature medicine.
2019
Academic Article
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Times cited: 239 -
Genomic and Transcriptomic Characterization of Papillary Microcarcinomas With Lateral Neck Lymph Node Metastases.
The Journal of clinical endocrinology and metabolism.
2019
Academic Article
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Times cited: 16 -
Regorafenib in Combination with First-Line Chemotherapy for Metastatic Esophagogastric Cancer.
The oncologist.
2019
Academic Article
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Times cited: 9 -
PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer.
NPJ breast cancer.
2019
Academic Article
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Times cited: 9900 -
Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma.
Human mutation.
2019
Academic Article
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Times cited: 20 -
Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 21 -
Resistance to TRK inhibition mediated by convergent MAPK pathway activation.
Nature medicine.
2019
Academic Article
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Times cited: 120 -
Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group.
Annals of oncology : official journal of the European Society for Medical Oncology.
2019
Academic Article
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Times cited: 89 -
Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology.
JCO precision oncology.
2019
Academic Article
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Times cited: 61 -
Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 64 -
Tumour lineage shapes BRCA-mediated phenotypes.
Nature.
2019
Academic Article
GET IT
Times cited: 221 -
Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 69 -
DNA methylation-based classification of sinonasal undifferentiated carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2019
Academic Article
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Times cited: 56 -
Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition.
PloS one.
2019
Academic Article
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Times cited: 10 -
Massively parallel sequencing analysis of benign melanocytic naevi.
Histopathology.
2019
Academic Article
GET IT
Times cited: 10 -
High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 241 -
Understanding inherited risk in unselected newly diagnosed patients with endometrial cancer.
JCO precision oncology.
2019
Academic Article
GET IT
Times cited: 96 -
Genomic landscape of inverted urothelial papilloma and urothelial papilloma of the bladder.
The Journal of pathology.
2019
Academic Article
GET IT
Times cited: 28 -
JAK2/PD-L1/PD-L2 (9p24.1) amplifications in renal cell carcinomas with sarcomatoid transformation: implications for clinical management.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2019
Academic Article
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Times cited: 43 -
Efficacy of Combined VEGFR1-3, PDGFα/β, and FGFR1-3 Blockade Using Nintedanib for Esophagogastric Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 10 -
Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade.
JAMA oncology.
2019
Academic Article
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Times cited: 335 -
The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement.
Human pathology.
2019
Academic Article
GET IT
Times cited: 28 -
Harnessing Clinical Sequencing Data for Survival Stratification of Patients with Metastatic Lung Adenocarcinomas.
JCO precision oncology.
2019
Academic Article
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Times cited: 26 -
Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers.
Nature.
2019
Academic Article
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Times cited: 6 - Correction: An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer. Cancer discovery. 2019 Academic Article GET IT
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Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid.
Nature.
2019
Academic Article
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Times cited: 268 -
Tumor mutational load predicts survival after immunotherapy across multiple cancer types.
Nature genetics.
2019
Academic Article
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Times cited: 1996 -
Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes.
Cancer.
2019
Academic Article
GET IT
Times cited: 20 -
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature.
2019
Academic Article
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Times cited: 28 -
Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma.
Blood.
2018
Academic Article
GET IT
Times cited: 123 -
Binimetinib plus Gemcitabine and Cisplatin Phase I/II Trial in Patients with Advanced Biliary Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 21 -
Next-Generation Sequencing-Based Assessment of JAK2, PD-L1, and PD-L2 Copy Number Alterations at 9p24.1 in Breast Cancer: Potential Implications for Clinical Management.
The Journal of molecular diagnostics : JMD.
2018
Academic Article
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Times cited: 18 -
EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer.
Cancer discovery.
2018
Academic Article
GET IT
Times cited: 98 -
Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors.
JAMA oncology.
2018
Academic Article
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Times cited: 109 -
Radioactive Iodine-Related Clonal Hematopoiesis in Thyroid Cancer Is Common and Associated With Decreased Survival.
The Journal of clinical endocrinology and metabolism.
2018
Academic Article
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Times cited: 26 -
Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer.
Cancer cell.
2018
Academic Article
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Times cited: 56 -
Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
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Times cited: 290 -
Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 316 -
Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 130 -
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2).
Science signaling.
2018
Academic Article
GET IT
Times cited: 43 -
Genomic Differences Between "Primary" and "Secondary" Muscle-invasive Bladder Cancer as a Basis for Disparate Outcomes to Cisplatin-based Neoadjuvant Chemotherapy.
European urology.
2018
Academic Article
GET IT
Times cited: 92 -
Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.
Journal of the National Cancer Institute.
2018
Academic Article
GET IT
Times cited: 142 -
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.
Cancer cell.
2018
Academic Article
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Times cited: 465 -
Clinical tumour sequencing for precision oncology: time for a universal strategy.
Nature reviews. Cancer.
2018
Academic Article
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Times cited: 25 -
Immunohistochemical analysis of estrogen receptor in breast cancer with ESR1 mutations detected by hybrid capture-based next-generation sequencing.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2018
Academic Article
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Times cited: 12 -
Phase II study of trastuzumab with modified docetaxel, cisplatin, and 5 fluorouracil in metastatic HER2-positive gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association.
2018
Academic Article
GET IT
Times cited: 14 -
Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 79 -
Genome doubling shapes the evolution and prognosis of advanced cancers.
Nature genetics.
2018
Academic Article
GET IT
Times cited: 268 -
Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 300 -
The emerging clinical relevance of genomics in cancer medicine.
Nature reviews. Clinical oncology.
2018
Review
GET IT
Times cited: 249 -
Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
GET IT
Times cited: 276 -
KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function.
Oncogene.
2018
Academic Article
GET IT
Times cited: 72 -
Multicenter Prospective Phase II Trial of Neoadjuvant Dose-Dense Gemcitabine Plus Cisplatin in Patients With Muscle-Invasive Bladder Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 94 -
Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Annals of surgical oncology.
2018
Academic Article
GET IT
Times cited: 14 -
Real-Time Genomic Characterization of Metastatic Pancreatic Neuroendocrine Tumors Has Prognostic Implications and Identifies Potential Germline Actionability.
JCO precision oncology.
2018
Academic Article
GET IT
Times cited: 45 -
Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
GET IT
Times cited: 164 -
The value of cell-free DNA for molecular pathology.
The Journal of pathology.
2018
Review
GET IT
Times cited: 81 -
Alterations in DNA Damage Response and Repair Genes as Potential Marker of Clinical Benefit From PD-1/PD-L1 Blockade in Advanced Urothelial Cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 343 -
HER kinase inhibition in patients with HER2- and HER3-mutant cancers.
Nature.
2018
Academic Article
GET IT
Times cited: 473 -
Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 882 -
Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Cancer cell.
2018
Academic Article
GET IT
Times cited: 441 -
Accelerating Discovery of Functional Mutant Alleles in Cancer.
Cancer discovery.
2017
Academic Article
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Times cited: 191 -
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.
Science (New York, N.Y.).
2017
Academic Article
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Times cited: 627 -
Clinical and molecular characterization of patients with cancer of unknown primary in the modern era.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
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Times cited: 64 -
Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
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Times cited: 67 -
Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 214 -
Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma.
2017
GET IT
Times cited: 2 -
Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
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Times cited: 236 -
Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data.
JCO precision oncology.
2017
Academic Article
GET IT
Times cited: 206 -
Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: new recommendations, methods, and considerations.
Familial cancer.
2017
Letter
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Times cited: 14 -
Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.
Cancer research.
2017
Academic Article
GET IT
Times cited: 53 -
Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.
JAMA.
2017
Academic Article
GET IT
Times cited: 289 -
The genetic landscape of endometrial clear cell carcinomas.
The Journal of pathology.
2017
Academic Article
GET IT
Times cited: 153 -
Oncologist use and perception of large panel next-generation tumor sequencing.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
GET IT
Times cited: 28 -
Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations.
Blood.
2017
Academic Article
GET IT
Times cited: 62 -
Prognostic Value of TERT Alterations, Mutational and Copy Number Alterations Burden in Urothelial Carcinoma.
European urology focus.
2017
Letter
GET IT
Times cited: 24 -
Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes.
Cell stem cell.
2017
Academic Article
GET IT
Times cited: 435 -
Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2017
Academic Article
GET IT
Times cited: 52 -
Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
GET IT
Times cited: 137 -
An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer.
Nature medicine.
2017
Academic Article
GET IT
Times cited: 107 -
Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma.
Oncotarget.
2017
Academic Article
GET IT
Times cited: 10 -
PTEN Loss-of-Function Alterations Are Associated With Intrinsic Resistance to BRAF Inhibitors in Metastatic Melanoma.
JCO precision oncology.
2017
Academic Article
GET IT
Times cited: 28 -
Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
GET IT
Times cited: 73 -
A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
GET IT
Times cited: 101 -
Frequent IDH2 R172 mutations in undifferentiated and poorly-differentiated sinonasal carcinomas.
The Journal of pathology.
2017
Academic Article
GET IT
Times cited: 66 -
A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 274 -
Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets.
European urology.
2017
Academic Article
GET IT
Times cited: 217 -
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.
Blood.
2017
Academic Article
GET IT
Times cited: 60 -
Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.
JCO precision oncology.
2017
Academic Article
GET IT
Times cited: 302 -
Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas.
JCO precision oncology.
2017
Academic Article
GET IT
Times cited: 37 -
Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing.
BMC medical genomics.
2017
Academic Article
GET IT
Times cited: 85 -
OncoKB: A Precision Oncology Knowledge Base.
JCO precision oncology.
2017
Academic Article
GET IT
Times cited: 394 -
AKT Inhibition in Solid Tumors With AKT1 Mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2017
Academic Article
GET IT
Times cited: 193 -
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
Nature medicine.
2017
Academic Article
GET IT
Times cited: 1922 -
Next-generation sequencing of urine specimens: A novel platform for genomic analysis in patients with non-muscle-invasive urothelial carcinoma treated with bacille Calmette-Guérin.
Cancer cytopathology.
2017
Academic Article
GET IT
Times cited: 24 -
Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 399 -
An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer.
2017
GET IT
Times cited: 67 -
Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
GET IT
Times cited: 149 -
Precision oncology: Charting a path forward to broader deployment of genomic profiling.
PLoS medicine.
2017
Academic Article
GET IT
Times cited: 13 -
Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival.
Molecular cancer research : MCR.
2017
Academic Article
GET IT
Times cited: 16 -
The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform.
JAMA oncology.
2017
Academic Article
GET IT
Times cited: 158 -
DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
GET IT
Times cited: 183 -
Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status: Clinical Validation in the Context of a Hybrid Capture-Based, Comprehensive Solid Tumor Genomic Profiling Assay.
The Journal of molecular diagnostics : JMD.
2016
Academic Article
GET IT
Times cited: 77 -
Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2016
Academic Article
GET IT
Times cited: 58 -
Clinical and genetic determinants of ovarian metastases from colorectal cancer.
Cancer.
2016
Academic Article
GET IT
Times cited: 36 -
Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
GET IT
Times cited: 57 -
Delivering on the promise of precision cancer medicine.
Genome medicine.
2016
Editorial Article
GET IT
Times cited: 6 -
Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma.
European urology.
2016
Academic Article
GET IT
Times cited: 151 -
T-DM1 Activity in Metastatic Human Epidermal Growth Factor Receptor 2-Positive Breast Cancers That Received Prior Therapy With Trastuzumab and Pertuzumab.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
GET IT
Times cited: 61 -
Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.
Nature communications.
2016
Academic Article
GET IT
Times cited: 120 -
Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
GET IT
Times cited: 121 -
Genomic characterization of response to chemoradiation in urothelial bladder cancer.
Cancer.
2016
Academic Article
GET IT
Times cited: 46 -
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
The New England journal of medicine.
2016
Academic Article
GET IT
Times cited: 1009 -
Osteosarcoma With Apparent Ewing Sarcoma Gene Rearrangement.
2016
GET IT
Times cited: 3 -
The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2016
Academic Article
GET IT
Times cited: 62 -
Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor.
Nature.
2016
Academic Article
GET IT
Times cited: 290 -
Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
GET IT
Times cited: 241 -
Genomic aberrations frequently alter chromatin regulatory genes in chordoma.
Genes, chromosomes & cancer.
2016
Academic Article
GET IT
Times cited: 46 -
A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2- Metastatic Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
GET IT
Times cited: 222 -
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer.
Lung cancer (Amsterdam, Netherlands).
2016
Academic Article
GET IT
Times cited: 49 -
Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
GET IT
Times cited: 128 -
Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center.
Pediatric blood & cancer.
2016
Academic Article
GET IT
Times cited: 27 -
Somatic PIK3CA mutations as a driver of sporadic venous malformations.
Science translational medicine.
2016
Academic Article
GET IT
Times cited: 107 -
KRAS and Combined KRAS/TP53 Mutations in Locally Advanced Rectal Cancer are Independently Associated with Decreased Response to Neoadjuvant Therapy.
Annals of surgical oncology.
2016
Academic Article
GET IT
Times cited: 63 -
Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
GET IT
Times cited: 175 -
Genetic analysis of five children with essential thrombocytosis identified mutations in cancer-associated genes with roles in transcriptional regulation.
Haematologica.
2016
Letter
GET IT
Times cited: 13 -
Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
GET IT
Times cited: 308 -
Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2016
Academic Article
GET IT
Times cited: 75 -
Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer.
Nature genetics.
2016
Academic Article
GET IT
Times cited: 118 -
Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers.
The Journal of clinical investigation.
2016
Academic Article
GET IT
Times cited: 680 -
What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC).
2016
GET IT
Times cited: 225 -
Investigation of Somatic GNAQ, GNA11, BAP1 and SF3B1 Mutations in Ophthalmic Melanocytomas.
Ocular oncology and pathology.
2016
Academic Article
GET IT
Times cited: 10 -
Genomic Biomarkers for the Prediction of Stage and Prognosis of Upper Tract Urothelial Carcinoma.
The Journal of urology.
2016
Academic Article
GET IT
Times cited: 32 -
Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.
JAMA oncology.
2016
Academic Article
GET IT
Times cited: 216 -
Profiling Non-Small Cell Lung Cancer: From Tumor to Blood.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Comment
GET IT
Times cited: 14 -
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.
Nucleic acids research.
2015
Academic Article
GET IT
Times cited: 25 -
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.
Nature communications.
2015
Academic Article
GET IT
Times cited: 495 -
Targeted exome sequencing profiles genetic alterations in leiomyosarcoma.
Genes, chromosomes & cancer.
2015
Academic Article
GET IT
Times cited: 30 -
Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Oncotarget.
2015
Academic Article
GET IT
Times cited: 82 -
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature.
2015
Academic Article
GET IT
Times cited: 162 -
NF1 Mutations Are Common in Desmoplastic Melanoma.
The American journal of surgical pathology.
2015
Academic Article
GET IT
Times cited: 80 -
Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia.
The New England journal of medicine.
2015
Academic Article
GET IT
Times cited: 245 -
ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma.
Oncotarget.
2015
Academic Article
GET IT
Times cited: 11 -
Extreme Outlier Analysis Identifies Occult Mitogen-Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer.
2015
GET IT
Times cited: 76 -
Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials.
Drug discovery today.
2015
Academic Article
GET IT
Times cited: 121 -
Genomic Characterization of Upper Tract Urothelial Carcinoma.
European urology.
2015
Academic Article
GET IT
Times cited: 165 -
Phase II Trial of Sorafenib in Patients with Chemotherapy Refractory Metastatic Esophageal and Gastroesophageal (GE) Junction Cancer.
PloS one.
2015
Academic Article
GET IT
Times cited: 35 -
Molecular Signature of Response to Pazopanib Salvage Therapy for Urothelial Carcinoma.
Clinical genitourinary cancer.
2015
Academic Article
GET IT
Times cited: 3 -
Somatic mutations in leukocytes infiltrating primary breast cancers.
NPJ breast cancer.
2015
Academic Article
GET IT
Times cited: 21 -
Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications.
The American journal of surgical pathology.
2015
Academic Article
GET IT
Times cited: 136 -
Consistent copy number changes and recurrent PRKAR1A mutations distinguish Melanotic Schwannomas from Melanomas: SNP-array and next generation sequencing analysis.
Genes, chromosomes & cancer.
2015
Academic Article
GET IT
Times cited: 37 -
Cutaneous squamous and neuroendocrine carcinoma: genetically and immunohistochemically different from Merkel cell carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2015
Academic Article
GET IT
Times cited: 62 -
Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2015
Academic Article
GET IT
Times cited: 41 -
Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping.
Cancer discovery.
2015
Academic Article
GET IT
Times cited: 454 -
A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases.
The oncologist.
2015
Academic Article
GET IT
Times cited: 54 -
Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases.
Cancer discovery.
2015
Academic Article
GET IT
Times cited: 114 -
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.
The Journal of molecular diagnostics : JMD.
2015
Academic Article
GET IT
Times cited: 1249 -
GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.
Journal of the American College of Surgeons.
2015
Academic Article
GET IT
Times cited: 127 -
Comprehensive mutation profiling by next-generation sequencing of effusion fluids from patients with high-grade serous ovarian carcinoma.
Cancer cytopathology.
2015
Academic Article
GET IT
Times cited: 26 -
Massively parallel sequencing identifies recurrent mutations in TP53 in thymic carcinoma associated with poor prognosis.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2015
Academic Article
GET IT
Times cited: 43 -
Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
GET IT
Times cited: 213 -
Clinical tumor sequencing: opportunities and challenges for precision cancer medicine.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
2015
Review
GET IT
Times cited: 44 -
Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.
Nature.
2014
Academic Article
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Times cited: 396 -
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.
Nature genetics.
2014
Academic Article
GET IT
Times cited: 386 -
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.
Genome biology.
2014
Academic Article
GET IT
Times cited: 259 -
Advancing clinical oncology through genome biology and technology.
Genome biology.
2014
Academic Article
GET IT
Times cited: 6 -
Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder.
European urology.
2014
Academic Article
GET IT
Times cited: 110 -
Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data.
The Journal of molecular diagnostics : JMD.
2014
Academic Article
GET IT
Times cited: 24 -
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.
Annals of oncology : official journal of the European Society for Medical Oncology.
2014
Academic Article
GET IT
Times cited: 273 -
Combined melanocytic and sweat gland neoplasm: cell subsets harbor an identical HRAS mutation in phacomatosis pigmentokeratotica.
2014
GET IT
Times cited: 11 -
Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy.
Cancer discovery.
2014
Academic Article
GET IT
Times cited: 97 -
Desmoplastic melanoma with sarcomatoid dedifferentiation.
2014
GET IT
Times cited: 33 -
Small-cell lung cancers in patients who never smoked cigarettes.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014
Academic Article
GET IT
Times cited: 89 -
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.
Science translational medicine.
2014
Academic Article
GET IT
Times cited: 98 -
Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry.
The American journal of surgical pathology.
2014
Academic Article
GET IT
Times cited: 184 -
Germline EGFR T790M mutation found in multiple members of a familial cohort.
2014
GET IT
Times cited: 50 -
PRADA: pipeline for RNA sequencing data analysis.
Bioinformatics (Oxford, England).
2014
Academic Article
GET IT
Times cited: 116 -
Recurrent SMARCA4 mutations in small cell carcinoma of the ovary.
Nature genetics.
2014
Academic Article
GET IT
Times cited: 246 -
Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014
Academic Article
GET IT
Times cited: 173 -
Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies.
2014
GET IT
Times cited: 67 -
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer research.
2014
Academic Article
GET IT
Times cited: 228 -
Basal cell carcinosarcoma with PTCH1 mutations in both epithelial and sarcomatoid primary tumor components and in the sarcomatoid metastasis.
2014
GET IT
Times cited: 16 -
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.
Nature communications.
2014
Academic Article
GET IT
Times cited: 429 -
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer.
Nature genetics.
2013
Academic Article
GET IT
Times cited: 813 -
Establishing the origin of metastatic deposits in the setting of multiple primary malignancies: the role of massively parallel sequencing.
2013
GET IT
Times cited: 32 -
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.
Nature biotechnology.
2013
Academic Article
GET IT
Times cited: 1491 -
Detecting somatic genetic alterations in tumor specimens by exon capture and massively parallel sequencing.
Journal of visualized experiments : JoVE.
2013
Academic Article
GET IT
Times cited: 62 -
Comprehensive molecular characterization of clear cell renal cell carcinoma.
Nature.
2013
Academic Article
GET IT
Times cited: 1721 -
Punctuated evolution of prostate cancer genomes.
Cell.
2013
Academic Article
GET IT
Times cited: 906 -
Harnessing massively parallel DNA sequencing for the personalization of cancer management.
Personalized medicine.
2013
Academic Article
GET IT
Times cited: 1 -
Phase II trial of MEK inhibitor selumetinib (AZD6244, ARRY-142886) in patients with BRAFV600E/K-mutated melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2013
Academic Article
GET IT
Times cited: 111 -
BRAF mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer.
Cancer.
2012
Academic Article
GET IT
Times cited: 147 -
Genome sequencing identifies a basis for everolimus sensitivity.
Science (New York, N.Y.).
2012
Academic Article
GET IT
Times cited: 578 -
Melanoma genome sequencing reveals frequent PREX2 mutations.
Nature.
2012
Academic Article
GET IT
Times cited: 576 -
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature.
2012
Academic Article
GET IT
Times cited: 5037 -
Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity.
Development (Cambridge, England).
2012
Academic Article
GET IT
Times cited: 25 -
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing.
Cancer discovery.
2011
Academic Article
GET IT
Times cited: 431 -
The mutational landscape of head and neck squamous cell carcinoma.
Science (New York, N.Y.).
2011
Academic Article
GET IT
Times cited: 1934 -
Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling.
2011
GET IT
Times cited: 797 -
The genomic complexity of primary human prostate cancer.
Nature.
2011
Academic Article
GET IT
Times cited: 990 -
Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.
PloS one.
2010
Academic Article
GET IT
Times cited: 25 -
Objective sequence-based subfamily classifications of mouse homeodomains reflect their in vitro DNA-binding preferences.
Nucleic acids research.
2010
Academic Article
GET IT
Times cited: 2 -
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.
The EMBO journal.
2010
Academic Article
GET IT
Times cited: 411 -
Integrative analysis of the melanoma transcriptome.
Genome research.
2010
Academic Article
GET IT
Times cited: 221 -
Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites.
Genomics.
2010
Academic Article
GET IT
Times cited: 36 -
Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts.
Genome biology.
2009
Academic Article
GET IT
Times cited: 164 -
Applications of genomics in melanoma oncogene discovery.
Hematology/oncology clinics of North America.
2009
Review
GET IT
Times cited: 23 -
Diversity and complexity in DNA recognition by transcription factors.
Science (New York, N.Y.).
2009
Academic Article
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Times cited: 726 -
High-resolution DNA-binding specificity analysis of yeast transcription factors.
Genome research.
2009
Academic Article
GET IT
Times cited: 321 -
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells.
Cancer research.
2009
Academic Article
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Times cited: 166 -
Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors.
Nature protocols.
2009
Academic Article
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Times cited: 260 -
Predicting the binding preference of transcription factors to individual DNA k-mers.
Bioinformatics (Oxford, England).
2008
Academic Article
GET IT
Times cited: 21 -
Design of compact, universal DNA microarrays for protein binding microarray experiments.
Journal of computational biology : a journal of computational molecular cell biology.
2008
Academic Article
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Times cited: 42 -
The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters.
Molecular microbiology.
2008
Academic Article
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Times cited: 115 -
Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences.
Cell.
2008
Academic Article
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Times cited: 465 -
Microarray analyses of newborn mouse ovaries lacking Nobox.
Biology of reproduction.
2007
Academic Article
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Times cited: 117 -
Inferring condition-specific transcription factor function from DNA binding and gene expression data.
Molecular systems biology.
2007
Conference Paper
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Times cited: 24 -
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome research.
2007
Academic Article
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Times cited: 83 -
Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities.
Nature biotechnology.
2006
Academic Article
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Times cited: 505 -
Protein binding microarrays (PBMs) for rapid, high-throughput characterization of the sequence specificities of DNA binding proteins.
Methods in molecular biology (Clifton, N.J.).
2006
Academic Article
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Times cited: 68 -
Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays.
Nature genetics.
2004
Academic Article
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Times cited: 299