Rafii, Shahin

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Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution. bioRxiv : the preprint server for biology. 2023 Article GET IT
Transcription factor induction of vascular blood stem cell niches in vivo. Developmental cell. 2023 Academic Article GET IT
Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response. Nature communications. 2023 Academic Article GET IT
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing. bioRxiv : the preprint server for biology. 2023 Article GET IT
Endothelial cell-leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities. Blood. 2023 Academic Article GET IT
Times cited: 1
Systems Biology Analysis of Temporal Dynamics That Govern Endothelial Response to Cyclic Stretch. Biomolecules. 2022 Review GET IT
Akt-Activated Endothelium Increases Cancer Cell Proliferation and Resistance to Treatment in Ovarian Cancer Cell Organoids. International journal of molecular sciences. 2022 Academic Article GET IT
Times cited: 2
Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis. Nature cardiovascular research. 2022 Academic Article GET IT
Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells. Cells. 2022 Academic Article GET IT
Regenerative medicine: postnatal approaches. The Lancet. Child & adolescent health. 2022 Review GET IT
Times cited: 6
Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome. The American journal of pathology. 2022 Academic Article GET IT
Times cited: 11
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell stem cell. 2022 Academic Article GET IT
Times cited: 12
Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics. Nature communications. 2022 Academic Article GET IT
Times cited: 8
Angiocrine ANGPTL2 executes HSC functions in endothelial niche. Blood. 2022 Editorial Article GET IT
Publisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. Nature cell biology. 2022 Article GET IT
Cardiovascular diseases disrupt the bone-marrow niche. Nature. 2022 Article GET IT
Times cited: 1
Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. Nature cell biology. 2021 Academic Article GET IT
Times cited: 7
Developmental angiocrine diversification of endothelial cells for organotypic regeneration. Developmental cell. 2021 Review GET IT
Times cited: 11
Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes. Genes & development. 2021 Academic Article GET IT
Times cited: 6
Attenuation of apoptotic cell detection triggers thymic regeneration after damage. Cell reports. 2021 Academic Article GET IT
Times cited: 2
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell stem cell. 2021 Academic Article GET IT
Times cited: 9
Endothelial reprogramming for vascular regeneration: Past milestones and future directions. Seminars in cell & developmental biology. 2021 Review GET IT
Times cited: 2
Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo. Cell reports. 2021 Academic Article GET IT
Times cited: 23
Direct reprogramming induces vascular regeneration post muscle ischemic injury. Molecular therapy : the journal of the American Society of Gene Therapy. 2021 Academic Article GET IT
Times cited: 12
Reversal of emphysema by restoration of pulmonary endothelial cells. The Journal of experimental medicine. 2021 Academic Article GET IT
Times cited: 20
Morphological characterization of Etv2 vascular explants using fractal analysis and atomic force microscopy. Microvascular research. 2021 Academic Article GET IT
Times cited: 2
Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies. Frontiers in physiology. 2021 Academic Article GET IT
Times cited: 2388
Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice. Communications biology. 2021 Academic Article GET IT
Times cited: 4
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
Times cited: 84
Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?. Radiation research. 2020 Review GET IT
Times cited: 28
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis. Nature. 2020 Academic Article GET IT
Times cited: 102
Megakaryocyte TGFβ1 partitions erythropoiesis into immature progenitor/stem cells and maturing precursors. Blood. 2020 Academic Article GET IT
Times cited: 8
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid. The Journal of experimental medicine. 2020 Academic Article GET IT
Times cited: 33
Angiocrine endothelium: from physiology to cancer. Journal of translational medicine. 2020 Review GET IT
Times cited: 41
Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1⁺ Leukemia. Cancer cell. 2020 Article GET IT
Molecular determinants of nephron vascular specialization in the kidney. Nature communications. 2019 Academic Article GET IT
Times cited: 48
Haematopoietic stem cell reprogramming and the hope for a universal blood product. FEBS letters. 2019 Review GET IT
Times cited: 3
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis. Nature cell biology. 2019 Academic Article GET IT
Times cited: 199
Akt-activated endothelium promotes ovarian cancer proliferation through notch activation. Journal of translational medicine. 2019 Academic Article GET IT
Times cited: 13
Endothelial cell adaptation in regeneration. Science (New York, N.Y.). 2018 Academic Article GET IT
Times cited: 31
In vitro conversion of adult murine endothelial cells to hematopoietic stem cells. Nature protocols. 2018 Academic Article GET IT
Times cited: 7
Generation of BMEC Lines and in vitro BMEC-HSPC Co-culture Assays. Bio-protocol. 2018 Academic Article GET IT
Testicular endothelial cells are a critical population in the germline stem cell niche. Nature communications. 2018 Academic Article GET IT
Times cited: 65
Blood flow forces liver growth. Nature. 2018 Comment GET IT
Times cited: 7
A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks. BMC bioinformatics. 2018 Academic Article GET IT
Times cited: 8
Laminar shear stress modulates endothelial luminal surface stiffness in a tissue-specific manner. Microcirculation (New York, N.Y. : 1994). 2018 Academic Article GET IT
Times cited: 10
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nature cell biology. 2018 Academic Article GET IT
Times cited: 37
Setting up the dermis for scar-free healing. Nature cell biology. 2018 Comment GET IT
Times cited: 2
The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells. Stem cell reports. 2018 Academic Article GET IT
Times cited: 21
Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos. The Journal of biological chemistry. 2018 Academic Article GET IT
Times cited: 30
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Science immunology. 2018 Academic Article GET IT
Times cited: 71
Isolation and Characterization of Mouse Organ-Specific Endothelial Transcriptomes. Methods in molecular biology (Clifton, N.J.). 2018 Academic Article GET IT
Times cited: 1
Open the gates: vascular neurocrine signaling mobilizes hematopoietic stem and progenitor cells. The Journal of clinical investigation. 2017 Comment GET IT
Times cited: 6
Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 47
Activated ovarian endothelial cells promote early follicular development and survival. Journal of ovarian research. 2017 Academic Article GET IT
Times cited: 5
Leukemic Cells "Gas Up" Leaky Bone Marrow Blood Vessels. Cancer cell. 2017 Comment GET IT
Times cited: 1
Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis. Science translational medicine. 2017 Academic Article GET IT
Times cited: 73
Plasmin regulation of acute cytokine storm. Blood. 2017 Comment GET IT
Times cited: 8
Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nature communications. 2017 Academic Article GET IT
Times cited: 53
Conversion of adult endothelium to immunocompetent haematopoietic stem cells. Nature. 2017 Academic Article GET IT
Times cited: 144
Catheter-directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of Cirrhosis. Radiology. 2017 Academic Article GET IT
Times cited: 7
A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells. Stem cell reports. 2017 Academic Article GET IT
Times cited: 35
A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 26
Dangerous Liaisons: Deviant Endothelium NOTCHes toward Tumor Metastasis. Cancer cell. 2017 Comment GET IT
Times cited: 3
Platelets prime hematopoietic and vascular niche to drive angiocrine-mediated liver regeneration. Signal transduction and targeted therapy. 2017 Academic Article GET IT
Times cited: 21
Sox17 drives functional engraftment of endothelium converted from non-vascular cells. Nature communications. 2017 Academic Article GET IT
Times cited: 15
Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2017 Academic Article GET IT
Times cited: 27
HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P₁) promotes regeneration and suppresses fibrosis in the liver. JCI insight. 2016 Academic Article GET IT
Times cited: 360
Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis. Nature communications. 2016 Academic Article GET IT
Times cited: 35
Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes. Cell reports. 2016 Academic Article GET IT
Times cited: 7
Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells. Cancer cell. 2016 Academic Article GET IT
Times cited: 82
Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates. Stem cells translational medicine. 2016 Academic Article GET IT
Times cited: 25
An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth. The Journal of experimental medicine. 2016 Academic Article GET IT
Times cited: 45
Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs. Radiation research. 2016 Review GET IT
Times cited: 15
Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. 2016 Academic Article GET IT
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells. Nature communications. 2016 Academic Article GET IT
Times cited: 23
Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. 2016 Academic Article GET IT
Times cited: 462
VEGF-B Improves Metabolic Health through Vascular Pruning of Fat. Cell metabolism. 2016 Comment GET IT
Times cited: 9
VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells. Oncotarget. 2016 Academic Article GET IT
Times cited: 16
Angiocrine functions of organ-specific endothelial cells. Nature. 2016 Review GET IT
Times cited: 558
Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis. Nature medicine. 2016 Academic Article GET IT
Times cited: 165
VEGF-A/VEGFR Inhibition Restores Hematopoietic Homeostasis in the Bone Marrow and Attenuates Tumor Growth. Cancer research. 2015 Academic Article GET IT
Times cited: 17
Direct conversion of human amniotic cells into endothelial cells without transitioning through a pluripotent state. Nature protocols. 2015 Academic Article GET IT
Times cited: 25
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 2015 Academic Article GET IT
Times cited: 194
Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells. Journal of cell science. 2015 Academic Article GET IT
Times cited: 10
Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC. PloS one. 2015 Academic Article GET IT
Times cited: 16
Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling. Developmental cell. 2015 Academic Article GET IT
Times cited: 62
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. The Journal of clinical investigation. 2015 Academic Article GET IT
Times cited: 55
Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model. Cell reports. 2015 Academic Article GET IT
Times cited: 90
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells. The Journal of clinical investigation. 2015 Academic Article GET IT
Times cited: 86
Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. Journal of translational medicine. 2015 Academic Article GET IT
Times cited: 40
Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration. Nature cell biology. 2015 Academic Article GET IT
Times cited: 106
Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling. Stem cell reports. 2015 Academic Article GET IT
Times cited: 31
Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties. PloS one. 2014 Academic Article GET IT
Times cited: 60
Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling. Journal of neuro-oncology. 2014 Academic Article GET IT
Times cited: 24
Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Molecular cancer therapeutics. 2014 Academic Article GET IT
Times cited: 28
Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nature biotechnology. 2014 Academic Article GET IT
Times cited: 177
Genome editing a mouse locus encoding a variant histone, H3.3B, to report on its expression in live animals. Genesis (New York, N.Y. : 2000). 2014 Academic Article GET IT
Times cited: 6
Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs. Cell stem cell. 2014 Academic Article GET IT
Times cited: 47
Activation of the vascular niche supports leukemic progression and resistance to chemotherapy. Experimental hematology. 2014 Academic Article GET IT
Times cited: 45
Two waves of de novo methylation during mouse germ cell development. Genes & development. 2014 Academic Article GET IT
Times cited: 90
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction. Nature. 2014 Academic Article GET IT
Times cited: 174
Evaluation of candidate spermatogonial markers ID4 and GPR125 in testes of adult human cadaveric organ donors. Andrology. 2014 Academic Article GET IT
Times cited: 24
Histone variant H3.3 is an essential maternal factor for oocyte reprogramming. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 72
Completely ES cell-derived mice produced by tetraploid complementation using inner cell mass (ICM) deficient blastocysts. PloS one. 2014 Academic Article GET IT
Times cited: 16
Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human acute myeloid leukemia. Leukemia. 2014 Academic Article GET IT
Times cited: 11
Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance. Cancer cell. 2014 Academic Article GET IT
Times cited: 169
Maladapted endothelial cells flip the mesenchymal switch. Science translational medicine. 2014 Comment GET IT
Times cited: 7
Trkb signaling in pericytes is required for cardiac microvessel stabilization. PloS one. 2014 Academic Article GET IT
Times cited: 36
Microparticles mediated cross-talk between tumoral and endothelial cells promote the constitution of a pro-metastatic vascular niche through Arf6 up regulation. Cancer microenvironment : official journal of the International Cancer Microenvironment Society. 2014 Academic Article GET IT
Times cited: 57
Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells. Stem cells (Dayton, Ohio). 2014 Academic Article GET IT
Times cited: 20
H3.3 replacement facilitates epigenetic reprogramming of donor nuclei in somatic cell nuclear transfer embryos. Nucleus (Austin, Tex.). 2014 Review GET IT
Times cited: 27
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity. Respiratory research. 2013 Academic Article GET IT
Times cited: 81
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature. 2013 Academic Article GET IT
Times cited: 424
Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity. Bioorganic & medicinal chemistry letters. 2013 Academic Article GET IT
Times cited: 9
Scaffold biomaterials for nano-pathophysiology. Advanced drug delivery reviews. 2013 Review GET IT
Times cited: 13
Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells. Cell. 2013 Academic Article GET IT
Times cited: 191
Retinal angiogenesis suppression through small molecule activation of p53. The Journal of clinical investigation. 2013 Academic Article GET IT
Times cited: 23
Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell reports. 2013 Academic Article GET IT
Times cited: 191
Endothelial cells provide a niche for placental hematopoietic stem/progenitor cell expansion through broad transcriptomic modification. Stem cell research. 2013 Academic Article GET IT
Times cited: 22
Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Developmental cell. 2013 Academic Article GET IT
Times cited: 438
Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance. Journal of translational medicine. 2013 Academic Article GET IT
Times cited: 300
Impaired endothelial progenitor cell mobilization and dysfunctional bone marrow stroma in diabetes mellitus. PloS one. 2013 Academic Article GET IT
Times cited: 60
Stem cells: Painkillers caught in blood-cell trafficking. Nature. 2013 Comment GET IT
Times cited: 1
Wading through the waves of human embryonic hemogenesis. Cell cycle (Georgetown, Tex.). 2013 Editorial Article GET IT
Times cited: 106
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. The Journal of experimental medicine. 2013 Academic Article GET IT
Times cited: 71
Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse. Annals of oncology : official journal of the European Society for Medical Oncology. 2013 Academic Article GET IT
Times cited: 67
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition. Blood. 2012 Academic Article GET IT
Times cited: 69
S1P and the birth of platelets. The Journal of experimental medicine. 2012 Review GET IT
Times cited: 19
Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell. 2012 Academic Article GET IT
Times cited: 172
It takes 2 to thrombopoies in the vascular niche. Blood. 2012 Comment GET IT
Times cited: 5
Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development. Developmental cell. 2012 Academic Article GET IT
Times cited: 231
Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells. Blood. 2012 Academic Article GET IT
Times cited: 77
Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cellular and molecular life sciences : CMLS. 2012 Academic Article GET IT
Times cited: 22
Serial monitoring of human systemic and xenograft models of leukemia using a novel vascular disrupting agent. Leukemia. 2012 Academic Article GET IT
Times cited: 12
Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer research. 2012 Academic Article GET IT
Times cited: 216
Generation of a vascular niche for studying stem cell homeostasis. Methods in molecular biology (Clifton, N.J.). 2012 Academic Article GET IT
Times cited: 13
Incremental increase in VEGFR1⁺ hematopoietic progenitor cells and VEGFR2⁺ endothelial progenitor cells predicts relapse and lack of tumor response in breast cancer patients. Breast cancer research and treatment. 2011 Academic Article GET IT
Times cited: 30
Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell. 2011 Academic Article GET IT
Times cited: 361
c-Kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis. PloS one. 2011 Academic Article GET IT
Times cited: 59
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Molecular cell. 2011 Academic Article GET IT
Times cited: 224
Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia. Cancer cell. 2011 Academic Article GET IT
Times cited: 112
Stromal-derived factor-1 delivered via hydrogel drug-delivery vehicle accelerates wound healing in vivo. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 2011 Academic Article GET IT
Times cited: 48
Lentiviral transduction and clonal selection of hESCs with endothelial-specific transgenic reporters. Current protocols in stem cell biology. 2011 Academic Article GET IT
Times cited: 8
Reproductive biology: In vitro sperm maturation. Nature. 2011 Comment GET IT
Times cited: 4
A target for antiangiogenic therapy: vascular endothelium derived from glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2011 Comment GET IT
Times cited: 10
Slitrks as emerging candidate genes involved in neuropsychiatric disorders. Trends in neurosciences. 2011 Review GET IT
Times cited: 74
Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12. International journal of cancer. 2011 Academic Article GET IT
Times cited: 92
Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17. Nature communications. 2011 Academic Article GET IT
Times cited: 117
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature. 2010 Academic Article GET IT
Times cited: 585
Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nature cell biology. 2010 Academic Article GET IT
Times cited: 304
Sept4/ARTS is required for stem cell apoptosis and tumor suppression. Genes & development. 2010 Academic Article GET IT
Times cited: 72
Plzf regulates germline progenitor self-renewal by opposing mTORC1. Cell. 2010 Academic Article GET IT
Times cited: 209
Role of cardiac myocyte CXCR4 expression in development and left ventricular remodeling after acute myocardial infarction. Circulation research. 2010 Academic Article GET IT
Times cited: 59
New dimensions in vascular engineering: opportunities for cancer biology. Tissue engineering. Part A. 2010 Academic Article GET IT
Times cited: 2
Cholesterol activates vascular niche and hematopoiesis. Blood. 2010 Comment GET IT
Times cited: 2
Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice. Nature medicine. 2010 Academic Article GET IT
Times cited: 244
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell. 2010 Academic Article GET IT
Times cited: 919
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell stem cell. 2010 Academic Article GET IT
Times cited: 501
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nature reviews. Cancer. 2010 Review GET IT
Times cited: 431
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nature biotechnology. 2010 Academic Article GET IT
Times cited: 248
Generation of stable co-cultures of vascular cells in a honeycomb alginate scaffold. Tissue engineering. Part A. 2010 Academic Article GET IT
Times cited: 32
Continuous delivery of stromal cell-derived factor-1 from alginate scaffolds accelerates wound healing. Cell transplantation. 2009 Academic Article GET IT
Times cited: 129
Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis. PloS one. 2009 Academic Article GET IT
Times cited: 28
Emerging biology of vascular wall progenitor cells in health and disease. Trends in molecular medicine. 2009 Review GET IT
Times cited: 60
Functional heterogeneity of the bone marrow vascular niche. Annals of the New York Academy of Sciences. 2009 Academic Article GET IT
Times cited: 53
Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency. The Journal of biological chemistry. 2009 Academic Article GET IT
Times cited: 9
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis. Circulation research. 2009 Academic Article GET IT
Times cited: 36
Surrogate markers predict angiogenic potential and survival in patients with glioblastoma multiforme. Neurosurgery. 2009 Academic Article GET IT
Times cited: 36
Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. The Journal of biological chemistry. 2009 Academic Article GET IT
Times cited: 110
Cerebral malaria is associated with low levels of circulating endothelial progenitor cells in African children. The American journal of tropical medicine and hygiene. 2009 Academic Article GET IT
Times cited: 15
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell stem cell. 2009 Academic Article GET IT
Times cited: 484
Cancer stem cells are everywhere. Nature medicine. 2009 Editorial Article GET IT
Times cited: 17
Angiogenesis and antiangiogenic therapy in non-Hodgkin's lymphoma. Annals of oncology : official journal of the European Society for Medical Oncology. 2008 Review GET IT
Times cited: 89
Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proceedings of the National Academy of Sciences of the United States of America. 2008 Academic Article GET IT
Times cited: 110
Inflammation joins the "niche". Cancer cell. 2008 Comment GET IT
Times cited: 42
The role of progenitor cells in the development of intimal hyperplasia. Journal of vascular surgery. 2008 Review GET IT
Times cited: 45
Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy. European heart journal. 2008 Academic Article GET IT
Times cited: 72
VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circulation research. 2008 Academic Article GET IT
Times cited: 139
Platelets, petechiae, and preservation of the vascular wall. The New England journal of medicine. 2008 Review GET IT
Times cited: 216
Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas. Proceedings of the National Academy of Sciences of the United States of America. 2008 Letter GET IT
Times cited: 48
CD34+ testicular stromal cells support long-term expansion of embryonic and adult stem and progenitor cells. Stem cells (Dayton, Ohio). 2008 Academic Article GET IT
Times cited: 30
Hitting the mother lode of tumor angiogenesis. Nature biotechnology. 2008 Comment GET IT
Times cited: 2
Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 431
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. The Journal of clinical investigation. 2008 Academic Article GET IT
Times cited: 793
A catalytic role for proangiogenic marrow-derived cells in tumor neovascularization. Cancer cell. 2008 Comment GET IT
Times cited: 71
Migratory neighbors and distant invaders: tumor-associated niche cells. Genes & development. 2008 Review GET IT
Times cited: 324
Cancer. A few to flip the angiogenic switch. Science (New York, N.Y.). 2008 Comment GET IT
Times cited: 58
The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood. 2007 Academic Article GET IT
Times cited: 65
Niche players: spermatogonial progenitors marked by GPR125. Cell cycle (Georgetown, Tex.). 2007 Academic Article GET IT
Times cited: 26
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature. 2007 Academic Article GET IT
Times cited: 353
Beta-galactosidase staining on bone marrow. The osteoclast pitfall. Histology and histopathology. 2007 Academic Article GET IT
Times cited: 55
Does N-cadherin regulate interaction of hematopoietic stem cells with their niches?. Cell stem cell. 2007 Comment GET IT
Times cited: 8
The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis. Trends in immunology. 2007 Academic Article GET IT
Times cited: 493
Thrombopoietic cells and the bone marrow vascular niche. Annals of the New York Academy of Sciences. 2007 Review GET IT
Times cited: 20
In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma. Cancer cell. 2007 Academic Article GET IT
Times cited: 134
Circulating endothelial progenitor cells correlate to stage in patients with invasive breast cancer. Breast cancer research and treatment. 2007 Academic Article GET IT
Times cited: 85
Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis. Experimental neurology. 2007 Academic Article GET IT
Times cited: 89
A novel family of slitrk genes is expressed on hematopoietic stem cells and leukemias. Leukemia. 2007 Letter GET IT
Times cited: 18
Tracking normalization of brain tumor vasculature by magnetic imaging and proangiogenic biomarkers. Cancer cell. 2007 Comment GET IT
Times cited: 35
Preparing the "soil": the premetastatic niche. Cancer research. 2006 Review GET IT
Times cited: 506
S100 chemokines mediate bookmarking of premetastatic niches. Nature cell biology. 2006 Comment GET IT
Times cited: 67
Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. The Journal of clinical investigation. 2006 Academic Article GET IT
Times cited: 88
Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2006 Academic Article GET IT
Times cited: 68
The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma. International journal of cancer. 2006 Academic Article GET IT
Times cited: 153
PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR. Nature. 2006 Academic Article GET IT
Times cited: 324
Activation of FGFR1beta signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells. Leukemia. 2006 Academic Article GET IT
Times cited: 45
Cancer interaction with the bone microenvironment: a workshop of the National Institutes of Health Tumor Microenvironment Study Section. The American journal of pathology. 2006 Conference Paper GET IT
Times cited: 31
Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue. Current opinion in hematology. 2006 Review GET IT
Times cited: 188
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nature medicine. 2006 Academic Article GET IT
Times cited: 564
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 2005 Academic Article GET IT
Times cited: 2539
Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. The Journal of clinical investigation. 2005 Academic Article GET IT
Times cited: 233
Osteopetrotic mouse stroma with thrombopoietin, c-kit ligand, and flk-2 ligand supports long-term mobilized CD34+ hematopoiesis in vitro. Stem cells and development. 2005 Academic Article GET IT
Times cited: 21
Simulated microgravity impairs leukemic cell survival through altering VEGFR-2/VEGF-A signaling pathway. Annals of biomedical engineering. 2005 Academic Article GET IT
Times cited: 15
The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology (Bethesda, Md.). 2005 Review GET IT
Times cited: 420
Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization. The Journal of experimental medicine. 2005 Academic Article GET IT
Times cited: 197
Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia. Circulation research. 2005 Academic Article GET IT
Times cited: 25
A role for niches in hematopoietic cell development. Hematology (Amsterdam, Netherlands). 2005 Academic Article GET IT
Times cited: 75
p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 18
Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells. Cancer research. 2005 Academic Article GET IT
Times cited: 61
Adenovirus vector E4 gene regulates connexin 40 and 43 expression in endothelial cells via PKA and PI3K signal pathways. Circulation research. 2005 Academic Article GET IT
Times cited: 21
Tie2 activation contributes to hemangiogenic regeneration after myelosuppression. Blood. 2005 Academic Article GET IT
Times cited: 104
AC133/CD133/Prominin-1. The international journal of biochemistry & cell biology. 2005 Review GET IT
Times cited: 321
Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue. Circulation. 2005 Academic Article GET IT
Times cited: 49
Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors. The Journal of clinical investigation. 2005 Academic Article GET IT
Times cited: 208
Vascular frontiers without borders: multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis. Cancer cell. 2004 Comment GET IT
Times cited: 26
The second international congress on myeloproliferative and myelodysplastic syndromes. Leukemia research. 2004 Conference Paper GET IT
Times cited: 6
Endostatin's endpoints-Deciphering the endostatin antiangiogenic pathway. Cancer cell. 2004 Review GET IT
Times cited: 36
Platelet-derived growth factor-AB promotes the generation of adult bone marrow-derived cardiac myocytes. Circulation research. 2004 Academic Article GET IT
Times cited: 73
Tumor necrosis factor alpha-stimulated endothelium: an inducer of dendritic cell development from hematopoietic progenitors and myeloid leukemic cells. Stem cells (Dayton, Ohio). 2004 Academic Article GET IT
Times cited: 23
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nature medicine. 2003 Academic Article GET IT
Times cited: 604
Adenovirus E4 gene promotes selective endothelial cell survival and angiogenesis via activation of the vascular endothelial-cadherin/Akt signaling pathway. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 39
Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133. Blood. 2003 Academic Article GET IT
Times cited: 137
Tumor vasculature address book: identification of stage-specific tumor vessel zip codes by phage display. Cancer cell. 2003 Comment GET IT
Times cited: 42
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer cell. 2003 Academic Article GET IT
Times cited: 225
Role of c-kit/Kit ligand signaling in regulating vasculogenesis. Thrombosis and haemostasis. 2003 Review GET IT
Times cited: 94
Adult cardiac stem cells--where do we go from here?. Science of aging knowledge environment : SAGE KE. 2003 Academic Article GET IT
Times cited: 4
Green fluorescent protein selectively induces HSP70-mediated up-regulation of COX-2 expression in endothelial cells. Blood. 2003 Academic Article GET IT
Times cited: 46
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nature medicine. 2003 Review GET IT
Times cited: 1458
Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science (New York, N.Y.). 2003 Academic Article GET IT
Times cited: 1350
Angiogenic factors reconstitute hematopoiesis by recruiting stem cells from bone marrow microenvironment. Annals of the New York Academy of Sciences. 2003 Academic Article GET IT
Times cited: 121
The regulation of hematopoietic stem cell and progenitor mobilization by chemokine SDF-1. Leukemia & lymphoma. 2003 Academic Article GET IT
Times cited: 108
Angiogenesis: vascular remodeling of the extracellular matrix involves metalloproteinases. Current opinion in hematology. 2003 Review GET IT
Times cited: 152
Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity. Leukemia. 2003 Academic Article GET IT
Times cited: 155
Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization. Trends in molecular medicine. 2003 Review GET IT
Times cited: 119
Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR. Cancer cell. 2003 Academic Article GET IT
Times cited: 210
Splitting vessels: keeping lymph apart from blood. Nature medicine. 2003 Article GET IT
Times cited: 21
Vaccination against tumor neovascularization: Promise and reality. Cancer cell. 2002 Review GET IT
Times cited: 29
Trophic effects of platelets on cultured endothelial cells are mediated by platelet-associated fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF). Thrombosis and haemostasis. 2002 Academic Article GET IT
Times cited: 112
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?. Nature reviews. Cancer. 2002 Review GET IT
Times cited: 629
VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells. Blood. 2002 Academic Article GET IT
Times cited: 338
Interleukin-1alpha promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2002 Academic Article GET IT
Times cited: 126
Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity. Circulation research. 2002 Academic Article GET IT
Times cited: 216
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nature medicine. 2002 Academic Article GET IT
Times cited: 561
Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras. Oncogene. 2002 Academic Article GET IT
Times cited: 63
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell. 2002 Academic Article GET IT
Times cited: 1524
Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function. Circulation research. 2002 Academic Article GET IT
Times cited: 287
Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors. Gene therapy. 2002 Review GET IT
Times cited: 152
VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition. Blood. 2002 Academic Article GET IT
Times cited: 226
Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood. 2002 Academic Article GET IT
Times cited: 226
Contribution of marrow-derived progenitors to vascular and cardiac regeneration. Seminars in cell & developmental biology. 2002 Review GET IT
Times cited: 146
Ex vivo expansion of stem and progenitor cells in co-culture of mobilized peripheral blood CD34+ cells on human endothelium transfected with adenovectors expressing thrombopoietin, c-kit ligand, and Flt-3 ligand. Journal of hematotherapy & stem cell research. 2002 Academic Article GET IT
Times cited: 23
A genetic approach to understanding tumor angiogenesis. Cold Spring Harbor symposia on quantitative biology. 2002 Academic Article GET IT
Times cited: 2
Negligible clinical effects of thalidomide in patients with myelofibrosis with myeloid metaplasia. Medical oncology (Northwood, London, England). 2002 Academic Article GET IT
Times cited: 41
The Id proteins and angiogenesis. Oncogene. 2001 Review GET IT
Times cited: 201
Anagrelide metabolite induces thrombocytopenia in mice by inhibiting megakaryocyte maturation without inducing platelet aggregation. Experimental hematology. 2001 Academic Article GET IT
Times cited: 15
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nature medicine. 2001 Academic Article GET IT
Times cited: 1652
Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proceedings of the National Academy of Sciences of the United States of America. 2001 Academic Article GET IT
Times cited: 259
Endothelial cell apoptotic genes associated with the pathogenesis of thrombotic microangiopathies: an application of oligonucleotide genechip technology. Microvascular research. 2001 Academic Article GET IT
Times cited: 13
Clonal variation in phenotype and life span of human embryonic fibroblasts (MRC-5) transduced with the catalytic component of telomerase (hTERT). Experimental cell research. 2001 Academic Article GET IT
Times cited: 33
CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. The Journal of cell biology. 2001 Academic Article GET IT
Times cited: 249
Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood. 2001 Academic Article GET IT
Times cited: 455
Infection of endothelium with E1(-)E4(+), but not E1(-)E4(-), adenovirus gene transfer vectors enhances leukocyte adhesion and migration by modulation of ICAM-1, VCAM-1, CD34, and chemokine expression. Circulation research. 2001 Academic Article GET IT
Times cited: 27
Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. The Journal of experimental medicine. 2001 Academic Article GET IT
Times cited: 610
Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells. Circulation research. 2001 Academic Article GET IT
Times cited: 750
Role of angiogenesis in the progression and treatment of prostate cancer. Cancer investigation. 2001 Review GET IT
Times cited: 28
The role of CXC chemokines in the regulation of tumor angiogenesis. Cancer investigation. 2001 Review GET IT
Times cited: 20
Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood. 2000 Academic Article GET IT
Times cited: 147
Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development (Cambridge, England). 2000 Academic Article GET IT
Times cited: 348
Downregulation of CXCR4 gene expression in primary human endothelial cells following infection with E1(-)E4(+) adenovirus gene transfer vectors. Molecular therapy : the journal of the American Society of Gene Therapy. 2000 Academic Article GET IT
Times cited: 8
Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis. Blood. 2000 Academic Article GET IT
Times cited: 262
Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. The Journal of clinical investigation. 2000 Academic Article GET IT
Times cited: 414
Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells. Possible role in the hematopoietic microenvironment. Experimental hematology. 2000 Academic Article GET IT
Times cited: 89
Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 2000 Academic Article GET IT
Times cited: 2093
Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1. The Journal of clinical investigation. 2000 Academic Article GET IT
Times cited: 223
Circulating endothelial precursors: mystery, reality, and promise. The Journal of clinical investigation. 2000 Comment GET IT
Times cited: 393
Stromal derived factor-1-induced chemokinesis of cord blood CD34(+) cells (long-term culture-initiating cells) through endothelial cells is mediated by E-selectin. Blood. 1999 Academic Article GET IT
Times cited: 91
Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector. Journal of virology. 1999 Academic Article GET IT
Times cited: 27
Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Molecular and cellular neurosciences. 1999 Academic Article GET IT
Times cited: 346
E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells. Blood. 1999 Academic Article GET IT
Times cited: 32
Interleukin-5 and the regulation of eosinophil production. Current opinion in hematology. 1999 Review GET IT
Times cited: 52
Regulation of transendothelial migration of hematopoietic progenitor cells. Annals of the New York Academy of Sciences. 1999 Review GET IT
Times cited: 61
[Adenovirus long-term expression of thrombopoietin in vivo: a new model for myeloproliferative syndrome and osteomyelofibrosis]. Schweizerische medizinische Wochenschrift. 1998 Academic Article GET IT
Times cited: 13
Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus. Nature. 1998 Academic Article GET IT
Times cited: 354
Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation. The Journal of experimental medicine. 1998 Academic Article GET IT
Times cited: 213
Evidence for circulating bone marrow-derived endothelial cells. Blood. 1998 Academic Article GET IT
Times cited: 1560
The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood. 1998 Academic Article GET IT
Times cited: 572
High-efficiency gene transfer into ex vivo expanded human hematopoietic progenitors and precursor cells by adenovirus vectors. Blood. 1998 Academic Article GET IT
Times cited: 73
Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis. Journal of immunology (Baltimore, Md. : 1950). 1998 Academic Article GET IT
Times cited: 73
The role of endothelium in the regulation of hematopoietic stem cell migration. Stem cells (Dayton, Ohio). 1998 Review GET IT
Times cited: 26
Expression of interleukin-5 by human bone marrow microvascular endothelial cells: implications for the regulation of eosinophilopoiesis in vivo. British journal of haematology. 1997 Academic Article GET IT
Times cited: 18
Regulation of hematopoiesis by microvascular endothelium. Leukemia & lymphoma. 1997 Review GET IT
Times cited: 134
Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity. The Journal of experimental medicine. 1997 Academic Article GET IT
Times cited: 357
Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proceedings of the National Academy of Sciences of the United States of America. 1997 Academic Article GET IT
Times cited: 639
Transendothelial migration of CD34+ and mature hematopoietic cells: an in vitro study using a human bone marrow endothelial cell line. Blood. 1997 Academic Article GET IT
Times cited: 115
The effects of Flk-2/flt3 ligand as compared with c-kit ligand on short-term and long-term proliferation of CD34+ hematopoietic progenitors elicited from human fetal liver, umbilical cord blood, bone marrow, and mobilized peripheral blood. Journal of hematotherapy. 1996 Academic Article GET IT
Times cited: 23
BMEC-1: a human bone marrow microvascular endothelial cell line with primary cell characteristics. Microvascular research. 1996 Academic Article GET IT
Times cited: 61
In vivo adenovirus vector-mediated transfer of the human thrombopoietin cDNA maintains platelet levels during radiation-and chemotherapy-induced bone marrow suppression. Blood. 1996 Academic Article GET IT
Times cited: 48
Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells. The Journal of experimental medicine. 1996 Academic Article GET IT
Times cited: 217
Density enrichment and characterization of hematopoietic progenitors and stem cells from umbilical cord blood. Bone marrow transplantation. 1996 Academic Article GET IT
Times cited: 11
Characterization of hematopoietic cells arising on the textured surface of left ventricular assist devices. The Annals of thoracic surgery. 1995 Academic Article GET IT
Times cited: 110
Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood. 1995 Academic Article GET IT
Times cited: 253
Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion. Blood. 1994 Academic Article GET IT
Times cited: 241
Perforin gene expression in stimulated human peripheral blood T cells studied by in situ hybridization and northern blotting analysis. Immunology letters. 1992 Academic Article GET IT
Times cited: 2
How lymphocytes kill. Annual review of medicine. 1990 Review GET IT
Times cited: 20
Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A. The Journal of experimental medicine. 1989 Academic Article GET IT
Times cited: 139
Iodine-131 MIBG scintigraphy in small cell lung cancer. European journal of nuclear medicine. 1989 Academic Article GET IT
Times cited: 6

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Funding awarded

Adaptable tissue-specific endothelial cells for organ regeneration awarded by National Heart, Lung, & Blood Institute Principal Investigator 2020 - 2027
Subcutaneous Transplantation of Pre-Vascularized Human Islets and SC-β cells to Treat Type I Diabetes awarded by JDRF Principal Investigator 2022 - 2024
Endothelial cell transplantation for multi-organ repair to counter radiation injury awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2018 - 2024
Addgene 699655 awarded by Addgene, Inc. Principal Investigator 2022 - 2023
Addgene 695996 awarded by Addgene, Inc. Principal Investigator 2022 - 2023
Molecular determinants of vascular niche maladaptation in dysregulated clonal evolution of stem cells awarded by Tri-Institutional Stem Cell Initiative (Weill Cornell) Principal Investigator 2021 - 2023

Charting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkit awarded by National Heart, Lung, & Blood Institute Co-Investigator 2022 - 2026
The Pulmonary Lymphatics in Inflammation and Disease awarded by National Heart, Lung, & Blood Institute Co-Investigator 2019 - 2024
In vitro modeling of blood brain barrier dysfunction on a chip to elucidate the pathogenesis of cerebral malaria awarded by National Heart, Lung, & Blood Institute Co-Investigator 2021 - 2023
Weill Cornell Training Program in Stem Cell Biology and Regenerative Medicine awarded by New York State Stem Cell Science (NYSTEM) Co-Investigator 2018 - 2023
H3.3-mediated epigenetic regulation of developmental bivalent genes for reprogramming and differentiation awarded by National Institute of General Medical Sciences Co-Investigator 2018 - 2023

Negative feedback regulation of growth factor signaling in adult spermatogonial stem cells awarded by National Institute of Child Health & Human Development Key Personnel 2021 - 2026
Methods for detection of dynamic intracellular signals in single adult spermatogonial stem cells awarded by National Institute of Child Health & Human Development Key Personnel 2023 - 2025

Dkk1-Endothelial Progenitor Cell Treatment for the Mitigation of Hematopoietic Radiation Injury awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2021 - 2024

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Background

education and training

M.D., Albert Einstein College of Medicine of Yeshiva University 1986
B.A., Cornell University 1982

Contact

full name

Shahin Rafii

primary email

srafii@med.cornell.edu

VIVO Weill Cornell Medical College

Shahin Rafii Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email