selected publications
- Molecular profiling of the stroke-induced alterations in the cerebral microvasculature reveals promising therapeutic candidates. Proceedings of the National Academy of Sciences of the United States of America. 2023 Academic Article GET IT
- Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimer’s disease. bioRxiv : the preprint server for biology. 2023 Article GET IT
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Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.
Nature communications.
2021
Academic Article
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Times cited: 13 -
Endothelial S1P1 Signaling Counteracts Infarct Expansion in Ischemic Stroke.
Circulation research.
2020
Academic Article
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Times cited: 50 -
The isolation and molecular characterization of cerebral microvessels.
Nature protocols.
2019
Academic Article
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Times cited: 36 -
Evaluation of S1PR1, pSTAT3, S1PR2, FOXP1 Expression in Aggressive, Mature B Cell Lymphomas.
Journal of hematopathology.
2019
Academic Article
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Times cited: 3 -
An engineered S1P chaperone attenuates hypertension and ischemic injury.
Science signaling.
2017
Academic Article
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Times cited: 74 -
Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1.
Proceedings of the National Academy of Sciences of the United States of America.
2017
Academic Article
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Times cited: 128 -
Sphingosine-1-Phosphate Signaling in Endothelial Disorders.
Current atherosclerosis reports.
2016
Review
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Times cited: 31 -
Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke.
Nature communications.
2015
Academic Article
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Times cited: 105 -
Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation.
Blood.
2013
Academic Article
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Times cited: 123 -
Sphingosine-1-phosphate receptor 1 in classical Hodgkin lymphoma: assessment of expression and role in cell migration.
Laboratory investigation; a journal of technical methods and pathology.
2013
Academic Article
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Times cited: 35 -
S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor.
The Journal of urology.
2009
Academic Article
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Times cited: 24 -
S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor.
Cancer letters.
2009
Academic Article
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Times cited: 51 -
Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2.
Molecular cancer research : MCR.
2008
Academic Article
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Times cited: 59 -
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.
The Journal of biological chemistry.
2008
Academic Article
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Times cited: 43 -
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina.
The Journal of clinical investigation.
2007
Academic Article
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Times cited: 191 -
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN.
Arteriosclerosis, thrombosis, and vascular biology.
2007
Academic Article
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Times cited: 250 -
Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization.
Cancer research.
2006
Academic Article
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Times cited: 256 -
GR 63799X, an EP3 receptor agonist, induced S phase arrest and 3T6 fibroblast growth inhibition.
European journal of pharmacology.
2005
Academic Article
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Times cited: 10 -
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Times cited: 133 -
Structural and functional characteristics of S1P receptors.
Journal of cellular biochemistry.
2004
Review
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Times cited: 411 -
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.
The Journal of biological chemistry.
2003
Academic Article
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Times cited: 351 -
Calcium-independent phospholipase A2 through arachidonic acid mobilization is involved in Caco-2 cell growth.
Journal of cellular physiology.
2002
Academic Article
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Times cited: 40 -
Role of EP(1) and EP(4) PGE(2) subtype receptors in serum-induced 3T6 fibroblast cycle progression and proliferation.
American journal of physiology. Cell physiology.
2002
Academic Article
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Times cited: 36 -
Role of phospholipases A(2) in growth-dependent changes in prostaglandin release from 3T6 fibroblasts.
Journal of cellular physiology.
2001
Academic Article
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Times cited: 10 -
Olive oil decreases both oxidative stress and the production of arachidonic acid metabolites by the prostaglandin G/H synthase pathway in rat macrophages.
The Journal of nutrition.
2001
Academic Article
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Times cited: 66 -
The effect of high molecular phospholipase A2 inhibitors on 3T6 fibroblast proliferation.
Biochemical pharmacology.
2001
Academic Article
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Times cited: 24 -
Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase.
The Journal of biological chemistry.
2000
Academic Article
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Times cited: 72 -
Regulation of prostaglandin E2 production by the superoxide radical and nitric oxide in mouse peritoneal macrophages.
Free radical research.
2000
Academic Article
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Times cited: 45 -
Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin.
Biochemical pharmacology.
1999
Academic Article
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Times cited: 38 -
Role of prostaglandin H synthase isoforms in murine ear edema induced by phorbol ester application on skin.
Prostaglandins & other lipid mediators.
1999
Academic Article
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Times cited: 28 -
Ketoprofen S(+) enantiomer inhibits prostaglandin production and cell growth in 3T6 fibroblast cultures.
European journal of pharmacology.
1999
Academic Article
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Times cited: 19 -
Induction by interleukin-1beta peptide of prostaglandin E2 formation via enhanced prostaglandin H synthase-2 expression in 3T6 fibroblasts.
Biochemical pharmacology.
1998
Academic Article
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Times cited: 4 -
Role of prostaglandin H synthase-2-mediated conversion of arachidonic acid in controlling 3T6 fibroblast growth.
The American journal of physiology.
1997
Academic Article
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Times cited: 42