Hollenberg, Anthony

Publications

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Co-Author Network

selected publications

The role of WD40 repeat-containing proteins in endocrine (dys)function. Journal of molecular endocrinology. 2023 Review GET IT
Regulation of Thyroid Hormone Levels by Hypothalamic Thyrotropin-Releasing Hormone Neurons. Thyroid : official journal of the American Thyroid Association. 2023 Academic Article GET IT
Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity. Cell reports. 2022 Academic Article GET IT
Nuclear corepressor SMRT acts as a strong regulator of both β-oxidation and suppressor of fibrosis in the differentiation process of mouse skeletal muscle cells. PloS one. 2022 Academic Article GET IT
Impact of the KL2/Catalyst Medical Research Investigator Training (CMeRIT) Program on the careers of early-stage clinical and translational investigators. Journal of clinical and translational science. 2022 Academic Article GET IT
Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP. Science signaling. 2021 Academic Article GET IT
Times cited: 6
Early Life Stress Affects the HPT Axis Response in a Sexually Dimorphic Manner. Endocrinology. 2021 Comment GET IT
Times cited: 3
Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis. Molecular metabolism. 2021 Academic Article GET IT
Times cited: 5
Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine. Frontiers in endocrinology. 2021 Review GET IT
Times cited: 68
Voices for Social Justice and Against Racism: An AAIM Perspective. The American journal of medicine. 2021 Academic Article GET IT
Times cited: 1
A joint industry-sponsored data monitoring committee model for observational, retrospective drug safety studies in the real-world setting. Pharmacoepidemiology and drug safety. 2020 Academic Article GET IT
SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem. Endocrinology. 2020 Academic Article GET IT
Times cited: 2
Prioritizing clinical research studies during the COVID-19 pandemic: lessons from New York City. The Journal of clinical investigation. 2020 Academic Article GET IT
Times cited: 7
Thyroid Hormone Signaling and the Liver. Hepatology (Baltimore, Md.). 2020 Review GET IT
Times cited: 64
Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone. PLoS genetics. 2020 Academic Article GET IT
Times cited: 14
Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action. PloS one. 2019 Academic Article GET IT
Times cited: 9
Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment. Circulation. 2019 Academic Article GET IT
Times cited: 37
Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment. Thyroid : official journal of the American Thyroid Association. 2019 Academic Article GET IT
Times cited: 37
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα. Nature communications. 2019 Academic Article GET IT
Times cited: 32
Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha. Thyroid : official journal of the American Thyroid Association. 2019 Academic Article GET IT
Times cited: 6
Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function. Science signaling. 2018 Academic Article GET IT
Times cited: 58
Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity. Antioxidants & redox signaling. 2018 Academic Article GET IT
Times cited: 38
T₃ Induces Both Markers of Maturation and Aging in Pancreatic β-Cells. Diabetes. 2018 Academic Article GET IT
Times cited: 14
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. The Journal of biological chemistry. 2017 Academic Article GET IT
Times cited: 10
A Field Experiment on Search Costs and the Formation of Scientific Collaborations. The review of economics and statistics. 2017 Academic Article GET IT
Times cited: 44
Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development (Cambridge, England). 2017 Academic Article GET IT
Times cited: 53
NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 10
Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. Endocrinology. 2017 Academic Article GET IT
Times cited: 109
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell metabolism. 2017 Academic Article GET IT
Times cited: 56
Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 130
The actions of thyroid hormone signaling in the nucleus. Molecular and cellular endocrinology. 2017 Review GET IT
Times cited: 42
New insights into thyroid hormone action. Pharmacology & therapeutics. 2017 Review GET IT
Times cited: 127
Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1. Stem cell reports. 2017 Academic Article GET IT
Times cited: 27
Regenerative therapy for hypothyroidism: Mechanisms and possibilities. Molecular and cellular endocrinology. 2016 Review GET IT
Times cited: 14
Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells. Autophagy. 2016 Academic Article GET IT
Times cited: 28
Liganded Thyroid Hormone Receptors Transactivate the DNA Methyltransferase 3a Gene in Mouse Neuronal Cells. Endocrinology. 2016 Academic Article GET IT
Times cited: 32
HDAC3 Is a Master Regulator of mTEC Development. Cell reports. 2016 Academic Article GET IT
Times cited: 19
The Endocrine Society Centennial: The Thyroid Leads the Way. Endocrinology. 2016 Academic Article GET IT
Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell stem cell. 2015 Academic Article GET IT
Times cited: 128
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. The Journal of biological chemistry. 2015 Academic Article GET IT
Times cited: 33
ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Molecular endocrinology (Baltimore, Md.). 2015 Academic Article GET IT
Times cited: 14
Age-Related Hearing Loss and Degeneration of Cochlear Hair Cells in Mice Lacking Thyroid Hormone Receptor β1. Endocrinology. 2015 Academic Article GET IT
Times cited: 24
Endocrine disorders in Fanconi anemia: recommendations for screening and treatment. The Journal of clinical endocrinology and metabolism. 2015 Review GET IT
Times cited: 60
NCoR1 and SMRT play unique roles in thyroid hormone action in vivo. Molecular and cellular biology. 2014 Academic Article GET IT
Times cited: 34
Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway. The Journal of clinical investigation. 2014 Academic Article GET IT
Times cited: 26
Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo. Endocrinology. 2014 Academic Article GET IT
Times cited: 30
Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. Molecular and cellular biology. 2014 Academic Article GET IT
Times cited: 39
Reprint of: policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Hormones and behavior. 2013 Editorial Article GET IT
Times cited: 4
Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 78
Reprint of: policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich, et al. Frontiers in neuroendocrinology. 2013 Editorial Article GET IT
Times cited: 1
Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Andrology. 2013 Letter GET IT
Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. European journal of endocrinology. 2013 Editorial Article GET IT
Times cited: 8
Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Hormone research in paediatrics. 2013 Letter GET IT
Times cited: 2
Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Endocrinology. 2013 Comment GET IT
Times cited: 28
Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 33
Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus. Molecular and cellular endocrinology. 2012 Academic Article GET IT
Times cited: 10
The thyroid axis is regulated by NCoR1 via its actions in the pituitary. Endocrinology. 2012 Academic Article GET IT
Times cited: 29
The in vivo role of nuclear receptor corepressors in thyroid hormone action. Biochimica et biophysica acta. 2012 Review GET IT
Times cited: 60
Minireview: The neural regulation of the hypothalamic-pituitary-thyroid axis. Endocrinology. 2012 Review GET IT
Times cited: 81
Metabolic health and nuclear-receptor sensitivity. The New England journal of medicine. 2012 Academic Article GET IT
Times cited: 11
Reducing systemic hypermetabolism by inducing hypothyroidism does not prolong survival in the SOD1-G93A mouse. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 2012 Academic Article GET IT
Times cited: 8
NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways. Cell metabolism. 2011 Academic Article GET IT
Times cited: 76
Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1). Proceedings of the National Academy of Sciences of the United States of America. 2011 Academic Article GET IT
Times cited: 36
PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism. Molecular endocrinology (Baltimore, Md.). 2011 Academic Article GET IT
Times cited: 23
The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis. Molecular endocrinology (Baltimore, Md.). 2011 Academic Article GET IT
Times cited: 65
Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity. The Journal of biological chemistry. 2011 Academic Article GET IT
Times cited: 23
Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. Molecular endocrinology (Baltimore, Md.). 2010 Academic Article GET IT
Times cited: 66
Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level. American journal of physiology. Endocrinology and metabolism. 2010 Academic Article GET IT
Times cited: 61
Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alpha. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 33
Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 109
The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo. Endocrinology. 2009 Academic Article GET IT
Times cited: 42
Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study. BMJ (Clinical research ed.). 2009 Academic Article GET IT
Times cited: 70
The ups and downs of thyrotropin-releasing hormone. Endocrinology. 2009 Comment GET IT
Times cited: 12
The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains. Molecular and cellular endocrinology. 2009 Academic Article GET IT
Times cited: 11
STAT3 targets the regulatory regions of gluconeogenic genes in vivo. Molecular endocrinology (Baltimore, Md.). 2009 Academic Article GET IT
Times cited: 84
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2008 Academic Article GET IT
Times cited: 124
Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor. Molecular cancer therapeutics. 2008 Academic Article GET IT
Times cited: 50
The thyroid and metabolism: the action continues. Cell metabolism. 2008 Conference Paper GET IT
Times cited: 19
The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor. Thyroid : official journal of the American Thyroid Association. 2008 Review GET IT
Times cited: 99
Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors. Cancer research. 2007 Academic Article GET IT
Times cited: 76
Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 170
Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor. The Journal of comparative neurology. 2005 Academic Article GET IT
Times cited: 98
The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists. The Journal of biological chemistry. 2004 Academic Article GET IT
Times cited: 120
Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells. Molecular endocrinology (Baltimore, Md.). 2004 Academic Article GET IT
Times cited: 66
Regulated production of a peroxisome proliferator-activated receptor-gamma ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes. The Journal of biological chemistry. 2004 Academic Article GET IT
Times cited: 155
The metabolic and cardiovascular effects of hyperthyroidism are largely independent of beta-adrenergic stimulation. Endocrinology. 2004 Academic Article GET IT
Times cited: 47
Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo. Endocrinology. 2004 Academic Article GET IT
Times cited: 105
Identification and characterization of melanocortin-4 receptor gene mutations in morbidly obese finnish children and adults. The Journal of clinical endocrinology and metabolism. 2004 Academic Article GET IT
Times cited: 72
Mutational analyses of RB and BRCA2 as candidate tumour suppressor genes in parathyroid carcinoma. Clinical endocrinology. 2003 Academic Article GET IT
Times cited: 61
Leucine at codon 428 in the ninth heptad of thyroid hormone receptor beta1 is necessary for interactions with the transcriptional cofactors and functions regardless of dimer formations. Thyroid : official journal of the American Thyroid Association. 2003 Academic Article GET IT
Times cited: 4
Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation. Molecular and cellular neurosciences. 2003 Academic Article GET IT
Times cited: 31
Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin. Endocrinology. 2003 Academic Article GET IT
Times cited: 259
Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2003 Academic Article GET IT
Times cited: 234
Cellular context of coregulator and adaptor proteins regulates human adenovirus 5 early region 1A-dependent gene activation by the thyroid hormone receptor. Molecular endocrinology (Baltimore, Md.). 2003 Academic Article GET IT
Times cited: 17
Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor. Molecular endocrinology (Baltimore, Md.). 2003 Academic Article GET IT
Times cited: 63
Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 99
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. The Journal of clinical investigation. 2002 Academic Article GET IT
Times cited: 454
Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Molecular endocrinology (Baltimore, Md.). 2002 Academic Article GET IT
Times cited: 104
Leptin and melanocortin signaling in the hypothalamus. Vitamins and hormones. 2002 Review GET IT
Times cited: 26
The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains. Molecular endocrinology (Baltimore, Md.). 2001 Academic Article GET IT
Times cited: 102
Transcriptional regulation of the leptin gene promoter in rat GH3 pituitary and C6 glioma cells. Molecular and cellular endocrinology. 2001 Academic Article GET IT
Times cited: 16
Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling. The Journal of clinical investigation. 2001 Academic Article GET IT
Times cited: 272
Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 178
cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 55
The nuclear corepressors recognize distinct nuclear receptor complexes. Molecular endocrinology (Baltimore, Md.). 2000 Academic Article GET IT
Times cited: 90
Leptin, nutrition, and the thyroid: the why, the wherefore, and the wiring. The Journal of clinical investigation. 2000 Comment GET IT
Times cited: 183
Thyroid hormone-independent interaction between the thyroid hormone receptor beta2 amino terminus and coactivators. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 66
ADD-1 provides major new insight into the mechanism of insulin action. Proceedings of the National Academy of Sciences of the United States of America. 1999 Letter GET IT
Times cited: 34
p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers. Molecular endocrinology (Baltimore, Md.). 1999 Academic Article GET IT
Times cited: 29
Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 109
Two separate NCoR (nuclear receptor corepressor) interaction domains mediate corepressor action on thyroid hormone response elements. Molecular endocrinology (Baltimore, Md.). 1998 Academic Article GET IT
Times cited: 64
Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 61
A unique role of the beta-2 thyroid hormone receptor isoform in negative regulation by thyroid hormone. Mapping of a novel amino-terminal domain important for ligand-independent activation. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 98
Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 269
Functional antagonism between CCAAT/Enhancer binding protein-alpha and peroxisome proliferator-activated receptor-gamma on the leptin promoter. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 233
Isoform variable action among thyroid hormone receptor mutants provides insight into pituitary resistance to thyroid hormone. Molecular endocrinology (Baltimore, Md.). 1997 Academic Article GET IT
Times cited: 51
Function of nuclear co-repressor protein on thyroid hormone response elements is regulated by the receptor A/B domain. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 86
A circulating, biologically inactive thyrotropin caused by a mutation in the beta subunit gene. The Journal of clinical investigation. 1996 Academic Article GET IT
Times cited: 108
Ligand-independent and -dependent functions of thyroid hormone receptor isoforms depend upon their distinct amino termini. The Journal of biological chemistry. 1995 Academic Article GET IT
Times cited: 73
The human thyrotropin-releasing hormone gene is regulated by thyroid hormone through two distinct classes of negative thyroid hormone response elements. Molecular endocrinology (Baltimore, Md.). 1995 Academic Article GET IT
Times cited: 167
A novel C-terminal domain in the thyroid hormone receptor selectively mediates thyroid hormone inhibition. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 49
c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 77
Multiple promoter elements in the human chorionic gonadotropin beta subunit genes distinguish their expression from the luteinizing hormone beta gene. Molecular and cellular endocrinology. 1994 Academic Article GET IT
Times cited: 37
Dynamic regulation of gonadotropin-releasing hormone receptor mRNA levels in the anterior pituitary gland during the rat estrous cycle. Endocrinology. 1993 Academic Article GET IT
Times cited: 101
Regulation of chorionic gonadotropin gene expression. Endocrine reviews. 1993 Review GET IT
Times cited: 184
Recent advances in studies of the molecular basis of endocrine disease. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1992 Review GET IT
Times cited: 5
Hypercalcemia with low-normal serum intact PTH: a novel presentation of primary hyperparathyroidism. 1991 GET IT
Times cited: 47
The gene encoding the beta-subunit of rat luteinizing hormone. Analysis of gene structure and evolution of nucleotide sequence. The Journal of biological chemistry. 1984 Academic Article GET IT
Times cited: 81

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Research

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Funding awarded

Corepressor regulation of nuclear receptor action awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator 2022 - 2023
Thyroid Follicular Cell Signaling and Development in Humans awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator 2021 - 2023
Corepressor regulation of nuclear receptor action awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator 2020 - 2023

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Background

education and training

M.D., University of Calgary Faculty of Medicine (Canada) 1986
A.B., Harvard College 1983

Contact

full name

Anthony Hollenberg

primary email

thollenb@med.cornell.edu

VIVO Weill Cornell Medical College

Anthony Hollenberg Adjunct Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email