Chen, Zhengming

Publications

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Co-Author Network

selected publications

PRMT5 Inhibition Drives Therapeutic Vulnerability to Combination Treatment with BCL-2 Inhibition in Mantle Cell Lymphoma. Blood advances. 2023 Academic Article GET IT
Biomarkers and cardiovascular outcomes in chimeric antigen receptor T-cell therapy recipients. European heart journal. 2023 Academic Article GET IT
Times cited: 20
Efficacy and Toxicity of CD19 Chimeric Antigen Receptor T Cell Therapy for Lymphoma in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis. Transplantation and cellular therapy. 2023 Academic Article GET IT
PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma. Blood. 2023 Academic Article GET IT
Multicenter phase 2 study of oral azacitidine (CC-486) plus CHOP as initial treatment for PTCL. Blood. 2023 Academic Article GET IT
Times cited: 5
Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege. The Journal of clinical investigation. 2023 Academic Article GET IT
Times cited: 2
Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis. bioRxiv : the preprint server for biology. 2023 Article GET IT
EBV-positive PCNSL in older patients: incidence, characteristics, tumor pathology, and outcomes across a large multicenter cohort. Leukemia & lymphoma. 2023 Academic Article GET IT
Screening Chest CT Prior to Allogenic Hematopoietic Stem Cell Transplantation. Transplantation and cellular therapy. 2023 Academic Article GET IT
BTG1 mutation yields supercompetitive B cells primed for malignant transformation. Science (New York, N.Y.). 2023 Academic Article GET IT
A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas. The Journal of clinical investigation. 2022 Academic Article GET IT
Times cited: 1
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants. Cell stem cell. 2022 Academic Article GET IT
Times cited: 111
TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma. Nature communications. 2022 Academic Article GET IT
Times cited: 2
Low-dose carbon monoxide suppresses metastatic progression of disseminated cancer cells. Cancer letters. 2022 Academic Article GET IT
Times cited: 3
Predictors of Covid-19 Vaccination Response After In-Vivo T-Cell-Depleted Stem Cell Transplantation. Transplantation and cellular therapy. 2022 Academic Article GET IT
Times cited: 4
Interval Appendectomy Specimens. Archives of pathology & laboratory medicine. 2022 Academic Article GET IT
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells. Circulation research. 2022 Academic Article GET IT
Times cited: 23
Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas. Blood. 2022 Academic Article GET IT
Times cited: 6
Initial Treatment Patterns and Survival Outcomes of Mantle Cell Lymphoma Patients Managed at Chinese Academic Centers in the Rituximab Era: A Real-World Study. Frontiers in oncology. 2022 Academic Article GET IT
Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival. Blood cancer discovery. 2021 Academic Article GET IT
Times cited: 5
RHAMM^B-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment. Molecular therapy oncolytics. 2021 Academic Article GET IT
Times cited: 3
Adenovirus viremia after in vivo T-cell depleted allo-transplant in adults: low lymphocyte counts are associated with uncontrolled viremia and fatal outcomes. Leukemia & lymphoma. 2021 Academic Article GET IT
Times cited: 1
Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes. Frontiers in immunology. 2021 Academic Article GET IT
Times cited: 2
Worsening Quality of Life in Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients in Active Surveillance: A 12-Month Longitudinal Study. Clinical lymphoma, myeloma & leukemia. 2021 Academic Article GET IT
Times cited: 3
High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer. Cancer letters. 2021 Academic Article GET IT
Times cited: 9
Postconvalescent SARS-CoV-2 IgG and Neutralizing Antibodies are Elevated in Individuals with Poor Metabolic Health. The Journal of clinical endocrinology and metabolism. 2021 Academic Article GET IT
Times cited: 16
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts. Circulation research. 2021 Academic Article GET IT
Times cited: 25
Association of Age With SARS-CoV-2 Antibody Response. JAMA network open. 2021 Academic Article GET IT
Times cited: 98
BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells. Blood. 2021 Academic Article GET IT
Times cited: 12
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. Nature immunology. 2021 Academic Article GET IT
Times cited: 17
GATA1 downregulation in prefibrotic and fibrotic stages of primary myelofibrosis and in the myelofibrotic progression of other myeloproliferative neoplasms. Leukemia research. 2020 Academic Article GET IT
Times cited: 1
The Association Between Age at Initiation of Alcohol Consumption and Type 2 Diabetes Mellitus: A Cohort Study of 0.5 Million Persons in China. American journal of epidemiology. 2020 Academic Article GET IT
Times cited: 4
Functional impact of cancer patient-associated Bcl-xL mutations. MedComm. 2020 Academic Article GET IT
COVID-19 Viral and Serology Testing in New York City Health Care Workers. American journal of clinical pathology. 2020 Academic Article GET IT
Times cited: 10
Multi-Institutional Prospective Validation of Prognostic mRNA Signatures in Early Stage Squamous Lung Cancer (Alliance). Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2020 Academic Article GET IT
Times cited: 14
Expression of the Receptor for Hyaluronic Acid-Mediated Motility (RHAMM) in Endometrial Cancer is Associated With Adverse Histologic Parameters and Tumor Progression. Applied immunohistochemistry & molecular morphology : AIMM. 2020 Academic Article GET IT
Times cited: 10
SARS-CoV-2 antibody characterization in emergency department, hospitalized and convalescent patients by two semi-quantitative immunoassays. Clinica chimica acta; international journal of clinical chemistry. 2020 Academic Article GET IT
Times cited: 28
miR-431 Promotes Metastasis of Pancreatic Neuroendocrine Tumors by Targeting DAB2 Interacting Protein, a Ras GTPase Activating Protein Tumor Suppressor. The American journal of pathology. 2020 Academic Article GET IT
Times cited: 13
Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial. Journal of Alzheimer's disease : JAD. 2020 Academic Article GET IT
Times cited: 38
Outcomes of Allogeneic Stem Cell Transplant for Elderly Patients with Hematologic Malignancies. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2019 Academic Article GET IT
Times cited: 9
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis. Cancer cell. 2019 Academic Article GET IT
Times cited: 60
A phase I trial of palbociclib plus bortezomib in previously treated mantle cell lymphoma. Leukemia & lymphoma. 2019 Academic Article GET IT
Times cited: 18
Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression. Molecular cancer. 2019 Letter GET IT
Times cited: 28
Cytomegalovirus reactivation in inflammatory bowel disease: an uncommon occurrence related to corticosteroid dependence. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2019 Academic Article GET IT
Times cited: 7
A phase 1 trial of ibrutinib plus palbociclib in previously treated mantle cell lymphoma. Blood. 2019 Academic Article GET IT
Times cited: 50
UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors. Endocrine-related cancer. 2019 Academic Article GET IT
Times cited: 13
Tumor Grade Is Prognostically Relevant Among Mismatch Repair Deficient Colorectal Carcinomas. The American journal of surgical pathology. 2018 Academic Article GET IT
Times cited: 7
Hotspot enumeration of CD8+ tumor-infiltrating lymphocytes using digital image analysis in triple-negative breast cancer yields consistent results. Human pathology. 2018 Academic Article GET IT
Times cited: 10
Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2018 Academic Article GET IT
Times cited: 55
Hot Spot and Whole-Tumor Enumeration of CD8⁺ Tumor-Infiltrating Lymphocytes Utilizing Digital Image Analysis Is Prognostic in Triple-Negative Breast Cancer. Clinical breast cancer. 2018 Academic Article GET IT
Times cited: 24
Immunohistochemical analysis of RHAMM expression in normal and neoplastic human tissues: a cell cycle protein with distinctive expression in mitotic cells and testicular germ cells. Oncotarget. 2018 Academic Article GET IT
Times cited: 24
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis. Nature communications. 2018 Academic Article GET IT
Times cited: 42
A retrospective study of R-DHAP/Ox for early progressing follicular lymphoma. British journal of haematology. 2017 Letter GET IT
Times cited: 3
Evaluation of a human adenovirus viral load assay using the Altona RealStar® PCR test. Diagnostic microbiology and infectious disease. 2017 Academic Article GET IT
Times cited: 5
Outcome of children and adolescents with relapsed Hodgkin lymphoma treated with high-dose therapy and autologous stem cell transplantation: the Memorial Sloan Kettering Cancer Center experience. Leukemia & lymphoma. 2017 Academic Article GET IT
Times cited: 8
Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R. British journal of haematology. 2017 Academic Article GET IT
Times cited: 91
MicroRNA-155 regulates casein kinase 1 gamma 2: a potential pathogenetic role in chronic lymphocytic leukemia. Blood cancer journal. 2017 Letter GET IT
Times cited: 7
Bone marrow biopsies do not impact response assessment for follicular lymphoma patients treated on clinical trials. British journal of haematology. 2017 Academic Article GET IT
Times cited: 10
The eIF4E inhibitor ribavirin as a potential antilymphoma therapeutic: early clinical data^. Leukemia & lymphoma. 2017 Letter GET IT
Times cited: 6
Oligomonocytic chronic myelomonocytic leukemia (chronic myelomonocytic leukemia without absolute monocytosis) displays a similar clinicopathologic and mutational profile to classical chronic myelomonocytic leukemia. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2017 Academic Article GET IT
Times cited: 42
Genetic defects of the IRF1-mediated major histocompatibility complex class I antigen presentation pathway occur prevalently in the JAK2 gene in non-small cell lung cancer. Oncotarget. 2017 Academic Article GET IT
Times cited: 13
Long-term outcomes, secondary malignancies and stem cell collection following bendamustine in patients with previously treated non-Hodgkin lymphoma. British journal of haematology. 2017 Academic Article GET IT
Times cited: 25
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression. eLife. 2017 Academic Article GET IT
Times cited: 42
Folate Receptor Alpha Expression Is Associated With Increased Risk of Recurrence in Triple-negative Breast Cancer. Clinical breast cancer. 2017 Academic Article GET IT
Times cited: 33
Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer. The Journal of biological chemistry. 2016 Academic Article GET IT
Times cited: 34
Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients. PloS one. 2016 Academic Article GET IT
Times cited: 23
Serum amyloid A immunohistochemical staining patterns in hepatitis. Histopathology. 2016 Academic Article GET IT
Times cited: 7
Bcl-xL promotes metastasis independent of its anti-apoptotic activity. Nature communications. 2016 Academic Article GET IT
Times cited: 54
Postibrutinib outcomes in patients with mantle cell lymphoma. Blood. 2016 Academic Article GET IT
Times cited: 191
Role of Surveillance Imaging in Patients With Peripheral T-Cell Lymphoma. Clinical lymphoma, myeloma & leukemia. 2015 Academic Article GET IT
Times cited: 9
Phosphohistone H3 expression correlates with manual mitotic counts and aids in identification of "hot spots" in fibroepithelial tumors of the breast. Human pathology. 2015 Academic Article GET IT
Times cited: 12
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science (New York, N.Y.). 2015 Academic Article GET IT
Times cited: 612
Evaluating the utility of trefoil factor 1 as a mammary-specific immunostain compared and in conjunction with GATA-3 and mammaglobin in the distinction between carcinoma of breast and lung. American journal of clinical pathology. 2015 Academic Article GET IT
Times cited: 2
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response. JAMA oncology. 2015 Academic Article GET IT
Times cited: 216
Cytopathologist-performed ultrasonography-guided fine-needle aspiration of head and neck lesions: the Weill Cornell experience. Journal of the American Society of Cytopathology. 2015 Academic Article GET IT
Times cited: 7
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer. Nature communications. 2014 Academic Article GET IT
Times cited: 494
Evidence for molecular differences in prostate cancer between African American and Caucasian men. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 120
Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes & development. 2014 Academic Article GET IT
Times cited: 93
Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification. Human pathology. 2014 Academic Article GET IT
Times cited: 24
Axl receptor tyrosine kinase expression in breast cancer. Journal of clinical pathology. 2014 Academic Article GET IT
Times cited: 42
Growth of the developing cerebral cortex is controlled by microRNA-7 through the p53 pathway. Cell reports. 2014 Academic Article GET IT
Times cited: 61
In search of the ideal immunopanel to distinguish metastatic mammary carcinoma from primary lung carcinoma: a tissue microarray study of 207 cases. Applied immunohistochemistry & molecular morphology : AIMM. 2014 Academic Article GET IT
Times cited: 16
Sentinel lymph node biopsy is a reliable method for lymph node evaluation in neoadjuvant chemotherapy-treated patients with breast cancer. The American surgeon. 2014 Academic Article GET IT
Times cited: 9
Impact of oncotype DX recurrence score in the management of breast cancer cases. Clinical breast cancer. 2013 Academic Article GET IT
Times cited: 17
ZNF365 promotes stability of fragile sites and telomeres. Cancer discovery. 2013 Academic Article GET IT
Times cited: 14
SP3, a reliable alternative to HercepTest in determining HER-2/neu status in breast cancer patients. Journal of clinical pathology. 2013 Academic Article GET IT
Times cited: 4
Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells. The international journal of biochemistry & cell biology. 2002 Academic Article GET IT
Times cited: 25
Effects of retinoic acid on metastasis and its related proteins in gastric cancer cells in vivo and in vitro. Acta pharmacologica Sinica. 2002 Academic Article GET IT
Times cited: 19
The effect pathway of retinoic acid through regulation of retinoic acid receptor alpha in gastric cancer cells. World journal of gastroenterology. 2001 Academic Article GET IT
Times cited: 29
Growth inhibition of gastric cancer cells by all-trans retinoic acid through arresting cell cycle progression. Chinese medical journal. 2001 Academic Article GET IT
Times cited: 17
Mechanism of inhibition on activator protein-1 activity by all-trans retinoic acid in gastric cancer cells. Chinese medical journal. 2000 Academic Article GET IT
Times cited: 13
Effect of gastrectomy on G-cell density and functional activity in dogs. World journal of gastroenterology. 2000 Academic Article GET IT
Times cited: 4
[Mechanism of retinoic acid receptor alpha-mediated growth inhibition of gastric cancer cells by all-trans retinoic acid]. Zhonghua zhong liu za zhi [Chinese journal of oncology]. 2000 Academic Article GET IT
Times cited: 2
Effect of all-trans retinoic acid on growth of xenograft tumor and its metastasis in nude mice. Chinese medical journal. 2000 Academic Article GET IT
Times cited: 6
[Regulation of cell cycle by retinoic acid in gastric cancer cells]. Shi yan sheng wu xue bao. 1999 Academic Article GET IT
Times cited: 5

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Research

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Funding awarded

Receptor for hyaluronan-mediated motility isoform B (RHAMM B) in Pancreatic Cancer Metastasis awarded by National Cancer Institute Co-Investigator 2022 - 2027
Preventing follicular lymphoma progression and transformation through precision therapy awarded by National Cancer Institute Co-Investigator 2022 - 2027
Mechanism-Based Targeting of Mantle Cell Lymphoma awarded by National Cancer Institute Co-Investigator 2018 - 2024
Novel Complex Structural Variants And Epigenetic Alterations Link The Genomes Of Prostate Cancer In African Americans With Outcome Disparity. awarded by United States Department of Defense Co-Investigator 2021 - 2023

Integrative Single Cell Isoform And Chromatin Accessibility Mapping Of Chronic Opioid Exposure In Cognitive Brain Areas In HIV awarded by National Institute on Drug Abuse Key Personnel 2021 - 2026
Characterization of Non-subtype B HIV-1 Reservoirs and its Association with Longitudinal Clinical Outcomes awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2021 - 2026
Tumor-metabolism-driven therapies to overcome TNBC immune resistance awarded by Breast Cancer Alliance Inc. Key Personnel 2023 - 2025
Investigating Cellular Immunometabolic Mechanisms Underlying HIV-Related Cardiovascular Disease Risk awarded by National Heart, Lung, & Blood Institute Key Personnel 2021 - 2025
A High Content Chemical Screen to Identify the Drug Candidates Promoting Human Beta Cell Proliferation awarded by National Institute of Diabetes & Digestive & Kidney Diseases Key Personnel 2020 - 2024
Role of the stromal microenvironment in B-cell lymphoma progression and immune escape awarded by National Cancer Institute Key Personnel 2019 - 2024
Live Imaging Analyses of the Mechanisms Required for Coordinated Urinary Tract Peristalsis in Lower-Order and Higher-Order Mammalian Species awarded by National Institute of Diabetes & Digestive & Kidney Diseases Key Personnel 2018 - 2024
Longitudinal functional genomics in mantle cell lymphoma therapy and drug resistance awarded by Leukemia & Lymphoma Society, Inc. Key Personnel 2018 - 2023

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Background

education and training

M.P.H., University of South Florida 2010
Ph.D., Xiamen University (China) 1999
M.S., Xiamen University (China) 1996
B.A., Xiamen University (China) 1991

Contact

full name

Zhengming Chen

primary email

zhc2006@med.cornell.edu

VIVO Weill Cornell Medical College

Zhengming Chen Assistant Professor of Population Health Sciences

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email