Journal of cell science

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B cell receptor-induced protein dynamics and the emerging role of SUMOylation revealed by proximity proteomics. 2023
Altered cohesin dynamics and H3K9 modifications contribute to mitotic defects in the cbf11Δ lipid metabolism mutant.. 136. 2023
Altered cohesin dynamics and H3K9 modifications contribute to mitotic defects in the cbf11Δ lipid metabolism mutant. 2023
TrkB deubiquitylation by USP8 regulates receptor levels and BDNF-dependent neuronal differentiation.. 133. 2020
Accurate measurement of fast endocytic recycling kinetics in real time.. 133. 2020
B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartments.. 133. 2019
High-density lipoprotein or cyclodextrin extraction of cholesterol from aggregated LDL reduces foam cell formation.. 132. 2019
The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge.. 132. 2019
The Plk1 kinase negatively regulates the Hedgehog signaling pathway by phosphorylating Gli1.. 132. 2019
Rab34 small GTPase is required for Hedgehog signaling and an early step of ciliary vesicle formation in mouse.. 131. 2018
Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane.. 131. 2018
The VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling.. 131. 2018
Distinct intracellular sAC-cAMP domains regulate ER Ca²⁺ signaling and OXPHOS function.. 130. 2017
A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export.. 130. 2017
Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.. 130. 2017
Multifunctional in vivo imaging of pancreatic islets during diabetes development.. 129. 2016
The Ca2+-activated Cl- channel Ano1 controls microvilli length and membrane surface area in the oocyte.. 129. 2016
Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis.. 129. 2016
Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse.. 129. 2016
Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ-14-3-3γ shuttling complex.. 128. 2015
A STIM1-dependent 'trafficking trap' mechanism regulates Orai1 plasma membrane residence and Ca²⁺ influx levels.. 128. 2015
Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells.. 128. 2015
The lamin-A/C-LAP2α-BAF1 protein complex regulates mitotic spindle assembly and positioning.. 128. 2015
IQGAP1 controls tight junction formation through differential regulation of claudin recruitment.. 128. 2015
Galectin-4-mediated transcytosis of transferrin receptor.. 127. 2014
Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.. 127. 2014
Annexin A2 mediates secretion of collagen VI, pulmonary elasticity and apoptosis of bronchial epithelial cells.. 127. 2013
eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases.. 126. 2013
Intramolecular shielding maintains the ER Ca²⁺ sensor STIM1 in an inactive conformation.. 126. 2013
Transient PKCα shuttling to the immunological synapse is governed by DGKζ and regulates L-selectin shedding.. 126. 2013
Downregulation of store-operated Ca2+ entry during mammalian meiosis is required for the egg-to-embryo transition.. 126. 2013
PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry.. 126. 2013
Cav1.1 controls frequency-dependent events regulating adult skeletal muscle plasticity.. 126. 2013
RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.. 126. 2012
Deficiency of the multi-copy mouse Y gene Sly causes sperm DNA damage and abnormal chromatin packaging.. 126. 2012
Mechanism of polarized lysosome exocytosis in epithelial cells.. 125. 2012
Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.. 125. 2012
Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.. 125. 2012
Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P₂ between distinct membrane pools.. 124. 2011
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.. 124. 2011
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.. 123. 2010
Regulation of store-operated Ca2+ entry during the cell cycle.. 123. 2010
Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors.. 121. 2008
Dissecting the role of PtdIns(4,5)P2 in endocytosis and recycling of the transferrin receptor.. 121. 2008
Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.. 120. 2007
PtdIns(3)P accumulation in triple lipid-phosphatase-deletion mutants triggers lethal hyperactivation of the Rho1p/Pkc1p cell-integrity MAP kinase pathway.. 118. 2005
Regulation of two insulin granule populations within the reserve pool by distinct calcium sources.. 118. 2005
Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis.. 118. 2005
Dynein light chain rp3 acts as a nuclear matrix-associated transcriptional modulator in a dynein-independent pathway.. 118. 2005
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus.. 116. 2003
Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae.. 116. 2003
Krh1p and Krh2p act downstream of the Gpa2p G(alpha) subunit to negatively regulate haploid invasive growth.. 116. 2003
SARA, a FYVE domain protein, affects Rab5-mediated endocytosis.. 115. 2002
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase.. 115. 2002
The C-terminal IgI domains of myosin-binding proteins C and H (MyBP-C and MyBP-H) are both necessary and sufficient for the intracellular crosslinking of sarcomeric myosin in transfected non-muscle cells.. 115. 2002
Active EGF receptors have limited access to PtdIns(4,5)P(2) in endosomes: implications for phospholipase C and PI 3-kinase signaling.. 115. 2002
Demonstration of insulin-responsive trafficking of GLUT4 and vpTR in fibroblasts.. 113 ( Pt 22). 2000
Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration.. 113 ( Pt 7). 2000
Syndecan-4 core protein is sufficient for the assembly of focal adhesions and actin stress fibers.. 112 ( Pt 20). 1999
Identification of the A-band localization domain of myosin binding proteins C and H (MyBP-C, MyBP-H) in skeletal muscle.. 112 ( Pt 1). 1999
Differential regulation of CXCR4 and CCR5 endocytosis.. 111 ( Pt 18). 1998
Overexpression of MAP4 inhibits organelle motility and trafficking in vivo.. 110 ( Pt 24). 1997
Differential induction of apoptosis in Swiss 3T3 cells by nitric oxide and the nitrosonium cation.. 110 ( Pt 18). 1997
Apical sorting of influenza hemagglutinin by transcytosis in retinal pigment epithelium.. 110 ( Pt 15). 1997
Rac is required for growth cone function but not neurite assembly.. 110 ( Pt 5). 1997
The polarity of the plasma membrane protein RET-PE2 in retinal pigment epithelium is developmentally regulated.. 109 ( Pt 13). 1996
The carboxyl terminus of myosin binding protein C (MyBP-C, C-protein) specifies incorporation into the A-band of striated muscle.. 109 ( Pt 1). 1996
Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology.. 108 ( Pt 12). 1995
Cyclic AMP modulates the rate of 'constitutive' exocytosis of apical membrane proteins in Madin-Darby canine kidney cells.. 108 ( Pt 5). 1995
Biosynthesis of glycosphingolipids is reduced in the absence of a vimentin intermediate filament network.. 107 ( Pt 12). 1994
Changes in yolk platelet pH during Xenopus laevis development correlate with yolk utilization. A quantitative confocal microscopy study.. 107 ( Pt 12). 1994
Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles.. 107 ( Pt 12). 1994
Astrocytes modulate retinal vasculogenesis: effects on fibronectin expression.. 107 ( Pt 9). 1994
Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy.. 107 ( Pt 8). 1994
Brefeldin A causes structural and functional alterations of the trans-Golgi network of MDCK cells.. 107 ( Pt 4). 1994
Structural reorganization of the rough endoplasmic reticulum without size expansion accounts for dexamethasone-induced secretory activity in AR42J cells.. 105 ( Pt 2). 1993
Immortalization of polarized rat retinal pigment epithelium.. 104 ( Pt 1). 1993
Induction of vacuolar apical compartments in the Caco-2 intestinal epithelial cell line.. 100 ( Pt 3). 1991
Fusion proteins containing a minimal GPI-attachment signal are apically expressed in transfected MDCK cells.. 99 ( Pt 3). 1991
A comparative study of three methods for the ultrastructural demonstration of glycogen in thin sections.. 9. 1971
What biologists want from their chloride reporters - a conversation between chemists and biologists. 2020
Message in a vesicle - trans-kingdom intercommunication at the vector-host interface. 2019
RNA tales - how embryos read and discard messages from mom. 2018
Autophagy in adhesion and migration. 2016
The role of mitotic kinases in coupling the centrosome cycle with the assembly of the mitotic spindle. 2014
Apical trafficking in epithelial cells: signals, clusters and motors. 2009
The hair cycle. 2006
Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. 1999

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