publication venue for
- Engineering CAR-T cells to activate small-molecule drugs in situ.. 18. 2021
- GCN2 kinase activation by ATP-competitive kinase inhibitors.. 18. 2021
- Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag.. 18. 2021
- The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.. 18. 2021
- Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.. 17. 2021
- Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.. 17. 2021
- Use of paramagnetic 19F NMR to monitor domain movement in a glutamate transporter homolog.. 16. 2020
- Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation.. 16. 2019
- Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin.. 15. 2019
- Mycobacterium tuberculosis releases an antacid that remodels phagosomes.. 15. 2019
- FTO controls reversible m6Am RNA methylation during snRNA biogenesis.. 15. 2019
- IFITM3 directly engages and shuttles incoming virus particles to lysosomes.. 15. 2019
- Genome-wide mapping reveals that deoxyuridine is enriched in the human centromeric DNA.. 14. 2018
- Distinguishing RNA modifications from noise in epitranscriptome maps.. 14. 2018
- A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.. 13. 2017
- Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex.. 13. 2017
- A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.. 13. 2017
- L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH.. 13. 2017
- Cbr1 is a Dph3 reductase required for the tRNA wobble uridine modification.. 12. 2016
- Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.. 12. 2016
- Identifying the functional contribution of the defatty-acylase activity of SIRT6.. 12. 2016
- Suppressors of superoxide production from mitochondrial complex III.. 11. 2015
- A new mechanism of allostery in a G protein-coupled receptor dimer.. 10. 2014
- DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets.. 10. 2014
- PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.. 10. 2014
- Pharmacological chaperones stabilize retromer to limit APP processing.. 10. 2014
- Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate.. 9. 2013
- Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap.. 9. 2013
- Identification of small molecules for human hepatocyte expansion and iPS differentiation.. 9. 2013
- Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells.. 9. 2013
- Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion.. 9. 2012
- Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.. 8. 2012
- A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion.. 8. 2012
- Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein.. 8. 2012
- Using transcriptome sequencing to identify mechanisms of drug action and resistance.. 8. 2012
- Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.. 7. 2011
- Conformational capture of the SAM-II riboswitch.. 7. 2011
- Cardiac glycosides are potent inhibitors of interferon-β gene expression.. 7. 2010
- Aminoglycoside activity observed on single pre-translocation ribosome complexes.. 6. 2010
- Stem cells: Metabolism regulates differentiation.. 6. 2010
- Substrate-dependent proton antiport in neurotransmitter:sodium symporters.. 6. 2009
- Relating diffusion along the substrate tunnel and oxygen sensitivity in hydrogenase.. 6. 2009
- Aminoglycoside activity observed on single pre-translocation ribosome complexes.. 6. 2009
- Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.. 5. 2009
- A small molecule that directs differentiation of human ESCs into the pancreatic lineage.. 5. 2009
- A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2).. 4. 2008
- Identification of a copper-binding metallothionein in pathogenic mycobacteria.. 4. 2008
- Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.. 3. 2007
- Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.. 3. 2006
- Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro.. 2. 2005
- Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis.. 1. 2005
- Publisher Correction: Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag.. 18. 2022
- Breaking the barriers of translation.. 4. 2008
- Methods: A small-molecule SMASh hit. 2015
- Membrane proteins: Through thick and thin. 2013
- Cancer therapeutics: Pulling the plug on BCL-X(L). 2013
- Methuselah antagonist extends life span. 2007
- Defining new chemical space for drug penetration into Gram-negative bacteria. 2020
- How pathogenic bacteria evade mammalian sabotage in the battle for iron. 2006
- Diversity-oriented synthesis: exploring the intersections between chemistry and biology. 2005