The ins and outs of MHC class II proteins in dendritic cells. uri icon

Overview

abstract

  • One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).

publication date

  • December 1, 2006

Research

keywords

  • Dendritic Cells
  • Histocompatibility Antigens Class II

Identity

Scopus Document Identifier

  • 33845459284

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2006.11.007

PubMed ID

  • 17174926

Additional Document Info

volume

  • 25

issue

  • 6