Immunity
Journal
Overview
publication venue for
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CD8+ T cells promote HIV latency by remodeling CD4+ T cell metabolism to enhance their survival, quiescence, and stemness..
56.
2023
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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup..
56.
2023
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The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer..
56.
2022
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Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer..
55.
2022
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Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses..
55.
2022
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Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway..
55.
2022
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IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment..
55.
2022
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Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors..
54.
2021
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Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses..
54.
2021
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Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets..
54.
2021
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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer..
54.
2021
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Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery..
54.
2021
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Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses..
53.
2020
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Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis..
52.
2020
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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling..
52.
2020
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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity..
52.
2020
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Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function..
51.
2019
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Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses..
51.
2019
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Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation..
51.
2019
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The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair..
51.
2019
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T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation..
51.
2019
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Cytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells..
50.
2019
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Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity..
50.
2019
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Dengue Virus Immunity Increases Zika Virus-Induced Damage during Pregnancy..
50.
2019
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The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus..
49.
2018
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Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis..
49.
2018
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Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance..
49.
2018
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Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers..
50.
2018
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Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44..
49.
2018
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Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses..
49.
2018
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Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance..
48.
2018
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Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses..
48.
2018
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Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses..
48.
2018
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Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors..
48.
2018
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Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction..
47.
2017
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White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection..
47.
2017
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Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF..
47.
2017
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Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals..
47.
2017
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Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches..
46.
2017
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A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure..
46.
2017
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Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life..
46.
2017
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The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity..
46.
2017
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A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells..
46.
2017
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Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation..
45.
2016
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Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer..
45.
2016
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Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion..
45.
2016
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Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects..
45.
2016
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Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection..
45.
2016
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Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region..
45.
2016
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mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation..
45.
2016
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Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I..
45.
2016
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The Costimulatory Receptor OX40 Inhibits Interleukin-17 Expression through Activation of Repressive Chromatin Remodeling Pathways..
44.
2016
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Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism..
44.
2016
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Gut Microbiota-Induced Immunoglobulin G Controls Systemic Infection by Symbiotic Bacteria and Pathogens..
44.
2016
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Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy..
44.
2016
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Interleukin-35 Limits Anti-Tumor Immunity..
44.
2016
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Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion..
44.
2016
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Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans..
43.
2015
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Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A..
43.
2015
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A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner..
43.
2015
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OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response..
42.
2015
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A dendritic-cell-stromal axis maintains immune responses in lymph nodes..
42.
2015
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The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus..
42.
2014
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Macrophage activation and polarization: nomenclature and experimental guidelines..
41.
2014
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Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation..
40.
2014
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Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers..
40.
2014
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Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers..
40.
2014
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The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells..
40.
2014
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Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation..
39.
2013
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Autophagy regulates phagocytosis by modulating the expression of scavenger receptors..
39.
2013
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SnapShot: innate lymphoid cells..
39.
2013
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Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling..
39.
2013
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Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora..
39.
2013
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Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals..
39.
2013
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The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome..
39.
2013
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Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines..
38.
2013
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T cell factor 1 is required for group 2 innate lymphoid cell generation..
38.
2013
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Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells..
38.
2013
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Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-β..
38.
2013
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Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease..
37.
2012
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Commensal bacteria calibrate the activation threshold of innate antiviral immunity..
37.
2012
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An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes..
36.
2012
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Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense..
36.
2012
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DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells..
34.
2011
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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6..
34.
2011
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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation..
34.
2011
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Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner..
34.
2011
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Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division..
34.
2011
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Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands..
34.
2011
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Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation..
34.
2011
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Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion..
34.
2011
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CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut..
34.
2010
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Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells..
33.
2010
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Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins..
32.
2010
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Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo..
32.
2010
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A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection..
31.
2009
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Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein..
30.
2009
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IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor..
29.
2008
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Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways..
29.
2008
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A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus..
29.
2008
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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces..
28.
2008
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Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76..
28.
2008
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Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1..
27.
2007
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The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis..
27.
2007
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Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL..
26.
2007
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FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin..
26.
2007
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Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors..
25.
2006
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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor..
25.
2006
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IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins..
24.
2006
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Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses..
23.
2005
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A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation..
22.
2005
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Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells..
22.
2005
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Regulatory T cell lineage specification by the forkhead transcription factor foxp3..
22.
2005
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SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1..
21.
2004
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Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells..
21.
2004
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Cognition and immunity; antibody impairs memory..
21.
2004
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Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors..
21.
2004
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Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation..
20.
2004
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Notch 1 signaling regulates peripheral T cell activation..
20.
2004
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Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential..
19.
2003
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SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils..
19.
2003
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Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6..
19.
2003
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Contribution of Vh gene replacement to the primary B cell repertoire..
19.
2003
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Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity..
19.
2003
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AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation..
18.
2003
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GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells..
18.
2003
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CDK inhibitor p18(INK4c) is required for the generation of functional plasma cells..
17.
2002
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Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo..
16.
2002
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DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection..
16.
2002
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Differential requirement for SLP-76 domains in T cell development and function..
15.
2001
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Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength..
14.
2001
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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2..
12.
2000
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SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis..
10.
1999
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Ikaros sets thresholds for T cell activation and regulates chromosome propagation..
10.
1999
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Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice..
10.
1999
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CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav..
8.
1998
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SHIP modulates immune receptor responses by regulating membrane association of Btk..
8.
1998
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Altered antigen presentation in mice lacking H2-O..
8.
1998
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Reversal of EBV immortalization precedes apoptosis in IL-6-induced human B cell terminal differentiation..
7.
1997
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Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides..
7.
1997
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Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin..
7.
1997
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Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6..
6.
1997
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Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation..
4.
1996
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FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway..
2.
1995
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Intracellular assembly and transport of endogenous peptide-MHC class II complexes..
1.
1994
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CD14 is a pattern recognition receptor..
1.
1994
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Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection..
51.
2019
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Not immune to stress: LBP's link to depression.
2023
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Good intentions gone wrong: The B cell block to epithelial repair.
2022
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In Situ Support of ILC Precursors.
2020
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MerTK Blockade Fuels Anti-tumor Immunity.
2020
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Mouse Watch: A Cautionary Tale.
2019
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TGF-β Inhibition and Immunotherapy: Checkmate.
2018
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Allergen Exposure: When Timing Is Everything.
2016
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Macrophages' Choice: Take It In or Keep It Out.
2016
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Taking the Broad View on B Cell Affinity Maturation.
2016
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PTPN22 in autoimmunity: different cell and different way.
2013
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Designing a type I interferon signaling phagosome.
2012
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Tracking interferon in autoimmunity.
2012
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Necroptosis turns TNF lethal.
2011
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A narrow circle of mutual friends.
2011
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The ins and outs of MHC class II proteins in dendritic cells.
2006
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Nonresolving inflammation redux.
2022
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Control of immunity via nutritional interventions.
2022
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Neuro-immune Interactions in the Tissues.
2020
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Gut Mycobiota in Immunity and Inflammatory Disease.
2019
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Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors.
2016
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Targeting T Cell Co-receptors for Cancer Therapy.
2016
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Caspases Connect Cell-Death Signaling to Organismal Homeostasis.
2016
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Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair.
2015
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Autophagy and cellular immune responses.
2013
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Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance.
2013
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Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease.
2012
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Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.
2009
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Control of regulatory T cell lineage commitment and maintenance.
2009
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Type I interferon in systemic lupus erythematosus and other autoimmune diseases.
2006
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Autoimmunity through cytokine-induced dendritic cell activation.
2004
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Nature's TRAIL--on a path to cancer immunotherapy.
2003
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T cell death and transplantation tolerance.
2001
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Cytokines and STATs: how can signals achieve specificity?
1995
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