selected publications
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Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference.
Oncoimmunology.
2023
Review
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Times cited: 511 - Autoimmunity to the modified self. Science (New York, N.Y.). 2023 Academic Article GET IT
- The broad spectrum of pathogenic autoreactivity. Nature reviews. Immunology. 2023 Academic Article GET IT
- The yin/yang balance of the MHC-self-immunopeptidome. Frontiers in immunology. 2022 Review GET IT
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PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes.
Science immunology.
2022
Academic Article
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Times cited: 8 -
Molecular Determinants Regulating the Plasticity of the MHC Class II Immunopeptidome.
Frontiers in immunology.
2022
Review
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Times cited: 8 - Author Correction: Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer. Nature reviews. Clinical oncology. 2022 Article GET IT
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Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice.
Scientific reports.
2022
Academic Article
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Times cited: 2 -
Advances in understanding and examining lymphatic function: relevance for understanding autoimmunity.
Current opinion in rheumatology.
2022
Review
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Times cited: 1 -
Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer.
Nature reviews. Clinical oncology.
2021
Review
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Times cited: 43 -
Autophagy in major human diseases.
The EMBO journal.
2021
Review
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Times cited: 318 -
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.
Nature communications.
2021
Academic Article
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Times cited: 17 -
A protocol for qualitative and quantitative measurement of endosomal processing using hot spot analysis.
STAR protocols.
2021
Academic Article
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Times cited: 1 -
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.
Nature communications.
2021
Academic Article
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Times cited: 17 -
Distinguishing Signal From Noise in Immunopeptidome Studies of Limiting-Abundance Biological Samples: Peptides Presented by I-Ab in C57BL/6 Mouse Thymus.
Frontiers in immunology.
2021
Academic Article
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Times cited: 5 -
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Cell.
2021
Academic Article
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Times cited: 99 -
Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery.
Immunity.
2021
Academic Article
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Times cited: 14 -
Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control.
The Journal of clinical investigation.
2021
Academic Article
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Times cited: 75 -
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
EMBO reports.
2020
Academic Article
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Times cited: 18 -
In vivo T1 mapping for quantifying glymphatic system transport and cervical lymph node drainage.
Scientific reports.
2020
Academic Article
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Times cited: 18 -
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
Proceedings of the National Academy of Sciences of the United States of America.
2020
Academic Article
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Times cited: 47 -
Lymphatic remodelling in response to lymphatic injury in the hind limbs of sheep.
Nature biomedical engineering.
2019
Academic Article
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Times cited: 5 -
Lymphatic Cannulation for Lymph Sampling and Molecular Delivery.
Journal of immunology (Baltimore, Md. : 1950).
2019
Academic Article
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Times cited: 13 -
Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells.
Nutrients.
2019
Academic Article
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Times cited: 16 -
The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells.
Frontiers in immunology.
2019
Review
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Times cited: 37 -
The negative effect of lipid challenge on autophagy inhibits T cell responses.
Autophagy.
2019
Academic Article
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Times cited: 15 -
Correction: Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and BRAF V600E mutation.
The Journal of experimental medicine.
2019
Academic Article
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Times cited: 10 -
Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients.
The Journal of experimental medicine.
2019
Academic Article
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Times cited: 76 -
Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and BRAF V600E mutation.
The Journal of experimental medicine.
2019
Academic Article
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Times cited: 77 -
Senescence cell-associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers.
JCI insight.
2019
Academic Article
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Times cited: 78 -
Message in a vesicle - trans-kingdom intercommunication at the vector-host interface.
Journal of cell science.
2019
Review
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Times cited: 12 -
In vitro model reveals a role for mechanical stretch in the remodeling response of lymphatic muscle cells.
Microcirculation (New York, N.Y. : 1994).
2018
Academic Article
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Times cited: 5 -
Contribution of the plasma and lymph Degradome and Peptidome to the MHC Ligandome.
Immunogenetics.
2018
Review
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Times cited: 8 -
Quantitative Profiling of the Lymph Node Clearance Capacity.
Scientific reports.
2018
Academic Article
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Times cited: 26 -
Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides.
Nature.
2018
Academic Article
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Times cited: 65 -
The Lymphatic Fluid.
International review of cell and molecular biology.
2018
Review
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Times cited: 16 -
NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release.
Frontiers in immunology.
2017
Academic Article
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Times cited: 13 -
Molecular definitions of autophagy and related processes.
The EMBO journal.
2017
Review
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Times cited: 1014 -
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.
Immunity.
2017
Academic Article
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Times cited: 191 -
Whole Chromosome Instability induces senescence and promotes SASP.
Scientific reports.
2016
Academic Article
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Times cited: 92 -
Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy.
The Journal of biological chemistry.
2016
Academic Article
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Times cited: 42 -
The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.
Infection and immunity.
2016
Academic Article
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Times cited: 32 -
Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo.
Blood.
2016
Academic Article
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Times cited: 57 -
The melting pot of the MHC II peptidome.
Current opinion in immunology.
2016
Review
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Times cited: 30 -
Autoimmune response to transthyretin in juvenile idiopathic arthritis.
JCI insight.
2016
Academic Article
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Times cited: 15 -
Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels.
Cell reports.
2016
Academic Article
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Times cited: 115 -
Role of Carbonyl Modifications on Aging-Associated Protein Aggregation.
Scientific reports.
2016
Academic Article
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Times cited: 67 -
Kupffer Cell Transplantation in Mice for Elucidating Monocyte/Macrophage Biology and for Potential in Cell or Gene Therapy.
The American journal of pathology.
2016
Academic Article
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Times cited: 24 -
The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity.
The Journal of biological chemistry.
2016
Academic Article
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Times cited: 41 -
Differential gene expression in human, murine, and cell line-derived macrophages upon polarization.
Experimental cell research.
2015
Academic Article
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Times cited: 108 -
Consequences of metabolic and oxidative modifications of cartilage tissue.
Nature reviews. Rheumatology.
2015
Review
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Times cited: 41 -
Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance.
Aging cell.
2015
Academic Article
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Times cited: 85 -
Corrigendum: Annexin A2 promotes phagophore assembly by enhancing Atg16⁺ vesicle biogenesis and homotypic fusion.
Nature communications.
2015
Article
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Times cited: 5 -
Lymph formation, composition and circulation: a proteomics perspective.
International immunology.
2015
Review
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Times cited: 67 -
Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging.
Aging cell.
2015
Academic Article
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Times cited: 118 -
Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion.
Nature communications.
2015
Academic Article
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Times cited: 30 -
Hydrodynamic size-based separation and characterization of protein aggregates from total cell lysates.
Nature protocols.
2014
Academic Article
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Times cited: 5 -
Molecular analysis of chromium and cobalt-related toxicity.
Scientific reports.
2014
Academic Article
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Times cited: 140 -
The lymph self-antigen repertoire.
Frontiers in immunology.
2013
Review
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Times cited: 32 -
Carrying yourself: self antigen composition of the lymphatic fluid.
Lymphatic research and biology.
2013
Academic Article
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Times cited: 5 -
Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage.
Blood.
2013
Academic Article
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Times cited: 47 -
Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification.
Chemistry & biology.
2013
Academic Article
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Times cited: 44 -
Disruption of multivesicular body vesicles does not affect major histocompatibility complex (MHC) class II-peptide complex formation and antigen presentation by dendritic cells.
The Journal of biological chemistry.
2013
Academic Article
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Times cited: 8 -
The lipid kinase PI4KIIIβ preserves lysosomal identity.
The EMBO journal.
2012
Academic Article
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Times cited: 88 -
Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics.
Journal of proteomics.
2012
Academic Article
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Times cited: 55 -
The annexin A2/S100A10 system in health and disease: emerging paradigms.
Journal of biomedicine & biotechnology.
2012
Review
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Times cited: 69 -
Orthopedic wear debris mediated inflammatory osteolysis is mediated in part by NALP3 inflammasome activation.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2012
Academic Article
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Times cited: 85 -
Age-related oxidative stress compromises endosomal proteostasis.
Cell reports.
2012
Academic Article
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Times cited: 71 -
Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.
Nature communications.
2012
Academic Article
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Times cited: 40 -
Optimizing dynamic interactions between a cardiac patch and inflammatory host cells.
Cells, tissues, organs.
2011
Review
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Times cited: 29 -
Mediators of the inflammatory response to joint replacement devices.
Nature reviews. Rheumatology.
2011
Review
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Times cited: 137 -
Oxidative stress, inflamm-aging and immunosenescence.
Journal of proteomics.
2011
Review
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Times cited: 226 - Chasing the elusive mammalian microautophagy. Autophagy. 2011 Academic Article GET IT
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Microautophagy of cytosolic proteins by late endosomes.
Developmental cell.
2011
Academic Article
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Times cited: 613 -
The lymph as a pool of self-antigens.
Trends in immunology.
2010
Academic Article
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Times cited: 56 -
Dendritic cell-mediated in vivo bone resorption.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
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Times cited: 33 -
Autoimmunity. The benefit of self-control.
Immunology and cell biology.
2010
Article
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Times cited: 3 -
An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.
PloS one.
2010
Academic Article
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Times cited: 51 -
Short communication: Methamphetamine treatment increases in vitro and in vivo HIV replication.
AIDS research and human retroviruses.
2009
Academic Article
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Times cited: 47 -
Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis.
Molecular immunology.
2009
Academic Article
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Times cited: 82 -
A mutation within the transmembrane domain of melanosomal protein Silver (Pmel17) changes lumenal fragment interactions.
European journal of cell biology.
2009
Academic Article
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Times cited: 8 -
Methamphetamine enhances histoplasmosis by immunosuppression of the host.
The Journal of infectious diseases.
2009
Academic Article
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Times cited: 59 -
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages.
Infection and immunity.
2009
Academic Article
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Times cited: 65 -
Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1.
The American journal of pathology.
2008
Academic Article
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Times cited: 86 -
Functional analysis of monocyte MHC class II compartments.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2008
Academic Article
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Times cited: 14 -
Immunogenecity of modified alkane polymers is mediated through TLR1/2 activation.
PloS one.
2008
Academic Article
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Times cited: 44 -
A monoclonal antibody to Histoplasma capsulatum alters the intracellular fate of the fungus in murine macrophages.
Eukaryotic cell.
2008
Academic Article
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Times cited: 31 -
Methamphetamine inhibits antigen processing, presentation, and phagocytosis.
PLoS pathogens.
2008
Academic Article
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Times cited: 113 -
GMCSF in the absence of other cytokines sustains human dendritic cell precursors with T cell regulatory activity and capacity to differentiate into functional dendritic cells.
Immunology letters.
2007
Academic Article
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Times cited: 33 -
Immune responses to lentiviral vectors.
Current gene therapy.
2007
Review
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Times cited: 83 -
The ins and outs of MHC class II proteins in dendritic cells.
Immunity.
2006
Comment
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Times cited: 14 -
CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate.
Journal of virology.
2006
Academic Article
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Times cited: 32 -
MHC class II compartment subtypes: structure and function.
Current opinion in immunology.
2005
Review
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Times cited: 52 -
Copolymer effects on microglia and T cells in the central nervous system of humanized mice.
European journal of immunology.
2005
Academic Article
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Times cited: 15 -
Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC.
Journal of immunology (Baltimore, Md. : 1950).
2005
Academic Article
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Times cited: 32 -
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells.
Nature immunology.
2005
Academic Article
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Times cited: 66 -
Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism.
Journal of immunology (Baltimore, Md. : 1950).
2005
Academic Article
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Times cited: 292 -
Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins.
Proceedings of the National Academy of Sciences of the United States of America.
2004
Academic Article
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Times cited: 40 -
Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms.
Proceedings of the National Academy of Sciences of the United States of America.
2004
Academic Article
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Times cited: 45 -
Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells.
Proceedings of the National Academy of Sciences of the United States of America.
2004
Academic Article
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Times cited: 37 -
Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding.
The Journal of biological chemistry.
2004
Academic Article
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Times cited: 47 -
The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia.
Blood.
2003
Academic Article
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Times cited: 92 -
Molecular interaction and enzymatic activity of macrophage migration inhibitory factor with immunorelevant peptides.
The Journal of biological chemistry.
2003
Academic Article
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Times cited: 32 -
Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation.
Journal of immunology (Baltimore, Md. : 1950).
2002
Academic Article
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Times cited: 90 -
Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis.
The Journal of clinical investigation.
2002
Academic Article
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Times cited: 40 -
IFN regulatory factor-1 regulates IFN-gamma-dependent cathepsin S expression.
Journal of immunology (Baltimore, Md. : 1950).
2002
Academic Article
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Times cited: 72 -
Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules.
The Journal of biological chemistry.
2001
Academic Article
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Times cited: 41 -
RANTES-induced chemokine cascade in dendritic cells.
Journal of immunology (Baltimore, Md. : 1950).
2001
Academic Article
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Times cited: 69 -
Developmental plasticity of CNS microglia.
Proceedings of the National Academy of Sciences of the United States of America.
2001
Academic Article
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Times cited: 260 -
Modulation of experimental autoimmune encephalomyelitis: effect of altered peptide ligand on chemokine and chemokine receptor expression.
Journal of neuroimmunology.
2000
Academic Article
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Times cited: 83 -
Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides.
The Journal of experimental medicine.
2000
Academic Article
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Times cited: 42 -
Abundant empty class II MHC molecules on the surface of immature dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America.
1999
Academic Article
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Times cited: 134 -
Extracellular antigen processing and presentation by immature dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America.
1999
Academic Article
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Times cited: 169 -
Antigen presenting capacity of brain microvasculature in altered peptide ligand modulation of experimental allergic encephalomyelitis.
Journal of neuroimmunology.
1999
Academic Article
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Times cited: 9 -
Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS.
Journal of neuroimmunology.
1998
Academic Article
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Times cited: 34 -
Staphylococcal enterotoxin B and tumor-necrosis factor-alpha-induced relapses of experimental allergic encephalomyelitis: protection by transforming growth factor-beta and interleukin-10.
European journal of immunology.
1995
Academic Article
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Times cited: 97 -
Tolerogenic forms of auto-antigens and cytokines in the induction of resistance to experimental allergic encephalomyelitis.
Journal of neuroimmunology.
1995
Academic Article
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Times cited: 40 -
Nerve growth factor production by lymphocytes.
Journal of immunology (Baltimore, Md. : 1950).
1994
Academic Article
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Times cited: 192 -
Human leucocyte-endothelial interactions in peripheral arterial occlusive disease.
European journal of clinical investigation.
1994
Academic Article
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Times cited: 22 -
Antagonistic effects of endogenous and exogenous TGF-beta and TNF on auto-immune diseases in mice.
Immunopharmacology and immunotoxicology.
1993
Academic Article
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Times cited: 30 -
Studies on the mechanisms by which transforming growth factor-beta (TGF-beta) protects against allergic encephalomyelitis. Antagonism between TGF-beta and tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950).
1993
Academic Article
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Times cited: 158 -
Dopamine receptors on human T- and B-lymphocytes.
Journal of neuroimmunology.
1993
Academic Article
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Times cited: 107 -
Leucocytes and free radicals in stable angina pectoris.
Japanese heart journal.
1992
Academic Article
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Times cited: 13 -
Plasma profiles of adrenocorticotropic hormone, cortisol, growth hormone and prolactin in patients with untreated Parkinson's disease.
Journal of neurology.
1991
Academic Article
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Times cited: 74 -
Free radical production in peripheral vascular disease. A risk for critical ischaemia?.
International angiology : a journal of the International Union of Angiology.
1991
Academic Article
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Times cited: 12 -
Sympathetic vascular function in patients with central dysautonomia.
Journal of neural transmission. Supplementum.
1991
Academic Article
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Times cited: 3 -
Use of pentoxifylline as an inhibitor of free radical generation in peripheral vascular disease. Results of a double-blind placebo-controlled study.
European journal of clinical pharmacology.
1991
Academic Article
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Times cited: 58 -
Temporal arteritis presenting as an extrapyramidal disorder.
1990
GET IT
Times cited: 3 - A technique for detecting leukocyte-derived free radical production. Haematologica. 1990 Letter GET IT
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Effect of physical training on leukocyte rheology throughout induced ischaemia.
International angiology : a journal of the International Union of Angiology.
1990
Academic Article
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Times cited: 2 -
Vascular uptake of 111-In-platelets and of 123-I-LDL.
Progress in clinical and biological research.
1990
Academic Article
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Times cited: 2 -
Leucocyte behaviour in controlled ischaemia of the calves.
Journal of clinical pathology.
1989
Academic Article
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Times cited: 14 -
Non-invasive cardiovascular monitoring in Shy-Drager syndrome.
1989
GET IT
Times cited: 2 -
Rheological behavior of white blood cells.
Stroke.
1989
Letter
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Times cited: 1 -
Risk factors for ischaemic brain infarction.
BMJ (Clinical research ed.).
1988
Letter
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Times cited: 1 - Effects of calcium antagonists and beta-adrenergic receptor blocking agents on cardiovascular rhythmicity. Panminerva medica. 1988 Academic Article GET IT