Linking differential chromatin loops to transcriptional decisions. uri icon

Overview

abstract

  • GATA-1 and GATA-2 control proliferation and differentiation of hematopoietic progenitor cells via transcriptional regulation. In this issue of Molecular Cell, Jing et al. (2008) demonstrate that GATA factor exchange on the Kit locus directs a transcriptional switch by reconfiguring chromatin loops.

publication date

  • February 1, 2008

Research

keywords

  • Chromatin Assembly and Disassembly
  • Erythropoiesis
  • GATA1 Transcription Factor
  • GATA2 Transcription Factor
  • Gene Silencing
  • Proto-Oncogene Proteins c-kit
  • Quantitative Trait Loci

Identity

Scopus Document Identifier

  • 38649083754

Digital Object Identifier (DOI)

  • 10.1016/j.molcel.2008.01.008

PubMed ID

  • 18243110

Additional Document Info

volume

  • 29

issue

  • 2