The fine structure of embryonic chick skeletal muscle cells differentiated in vitro. Academic Article uri icon

Overview

abstract

  • Dissociated myoblasts from 12-day chick embryos were cultured in monolayer, and the differentiation of skeletal muscle cells was studied by electron microscopy. The results have revealed a striking ultrastructural similarity between the in vivo and the in vitro developing muscle, particularly with respect to the myofibrils and sarcoplasmic reticulum. This study demonstrates that all the characteristic organelles of mature skeletal muscle can develop in vitro in the absence of nerves.

publication date

  • November 1, 1967

Research

keywords

  • Cell Differentiation
  • Chick Embryo
  • Muscles

Identity

PubMed Central ID

  • PMC2107131

Scopus Document Identifier

  • 0014147796

Digital Object Identifier (DOI)

  • 10.1083/jcb.35.2.445

PubMed ID

  • 4861777

Additional Document Info

volume

  • 35

issue

  • 2