Fischman, Donald Alan

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Two protein kinase C isoforms, δ and ε, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 Academic Article GET IT
Times cited: 18
Hiding in plain sight: uncovering a new function of vitamin A in redox signaling. Biochimica et biophysica acta. 2011 Review GET IT
Times cited: 14
Regulation of intermediary metabolism by the PKCdelta signalosome in mitochondria. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2010 Academic Article GET IT
Times cited: 40
Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 Academic Article GET IT
Times cited: 65
Embryonic chick corneal epithelium: a model system for exploring cell-matrix interactions. Developmental dynamics : an official publication of the American Association of Anatomists. 2008 Review GET IT
Times cited: 11
Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008 Academic Article GET IT
Times cited: 59
Myosin flares and actin leptomeres as myofibril assembly/disassembly intermediates in sonic muscle fibers. Cell and tissue research. 2006 Academic Article GET IT
Times cited: 3
Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain. The Journal of cell biology. 2004 Academic Article GET IT
Times cited: 144
Evidence for an extracellular matrix bridge guiding proepicardial cell migration to the myocardium of chick embryos. Developmental dynamics : an official publication of the American Association of Anatomists. 2003 Academic Article GET IT
Times cited: 94
Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2002 Academic Article GET IT
Times cited: 244
The C-terminal IgI domains of myosin-binding proteins C and H (MyBP-C and MyBP-H) are both necessary and sufficient for the intracellular crosslinking of sarcomeric myosin in transfected non-muscle cells. Journal of cell science. 2002 Academic Article GET IT
Times cited: 35
The 2000 Henry Gray Award. The Anatomical record. 2000 Academic Article GET IT
Slow tonic muscle fibers in the thyroarytenoid muscles of human vocal folds; a possible specialization for speech. The Anatomical record. 1999 Academic Article GET IT
Times cited: 42
The interface between MyBP-C and myosin: site-directed mutagenesis of the CX myosin-binding domain of MyBP-C. Journal of muscle research and cell motility. 1999 Academic Article GET IT
Times cited: 40
Identification of the A-band localization domain of myosin binding proteins C and H (MyBP-C, MyBP-H) in skeletal muscle. Journal of cell science. 1999 Academic Article GET IT
Times cited: 69
What role will chairs of discipline-based subjects play in the evolving medical school of the future?. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1998 Academic Article GET IT
Times cited: 5
Isoform-specific interaction of the myosin-binding proteins (MyBPs) with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 48
Skeletal muscle-specific myosin binding protein-H is expressed in Purkinje fibers of the cardiac conduction system. Circulation research. 1997 Academic Article GET IT
Times cited: 30
The use of replication-defective retroviruses for cell lineage studies of myogenic cells. Methods in cell biology. 1997 Review GET IT
Times cited: 13
Modulation of myosin filament organization by C-protein family members. Molecular biology of the cell. 1996 Academic Article GET IT
Times cited: 51
The carboxyl terminus of myosin binding protein C (MyBP-C, C-protein) specifies incorporation into the A-band of striated muscle. Journal of cell science. 1996 Academic Article GET IT
Times cited: 103
The polyclonal origin of myocyte lineages. Annual review of physiology. 1996 Review GET IT
Times cited: 53
Antisense suppression of skeletal muscle myosin light chain-1 biosynthesis impairs myofibrillogenesis in cultured myotubes. Journal of muscle research and cell motility. 1995 Academic Article GET IT
Times cited: 14
Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development. Proceedings of the National Academy of Sciences of the United States of America. 1995 Academic Article GET IT
Times cited: 165
Sequential appearance of muscle-specific proteins in myoblasts as a function of time after cell division: evidence for a conserved myoblast differentiation program in skeletal muscle. Cell motility and the cytoskeleton. 1994 Academic Article GET IT
Times cited: 130
The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif. The Journal of cell biology. 1993 Academic Article GET IT
Times cited: 170
Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment. European journal of biochemistry. 1993 Academic Article GET IT
Times cited: 103
Human myosin-binding protein H (MyBP-H): complete primary sequence, genomic organization, and chromosomal localization. Genomics. 1993 Academic Article GET IT
Times cited: 40
Molecular cloning of chicken myosin-binding protein (MyBP) H (86-kDa protein) reveals extensive homology with MyBP-C (C-protein) with conserved immunoglobulin C2 and fibronectin type III motifs. The Journal of biological chemistry. 1993 Academic Article GET IT
Times cited: 59
Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels. Proceedings of the National Academy of Sciences of the United States of America. 1992 Academic Article GET IT
Times cited: 339
Clonal analysis of cardiac morphogenesis in the chicken embryo using a replication-defective retrovirus. III: Polyclonal origin of adjacent ventricular myocytes. Developmental dynamics : an official publication of the American Association of Anatomists. 1992 Academic Article GET IT
Times cited: 87
Expression of sarcomeric myosin in the presumptive myocardium of chicken embryos occurs within six hours of myocyte commitment. Developmental dynamics : an official publication of the American Association of Anatomists. 1992 Academic Article GET IT
Times cited: 90
Clonal analysis of cardiac morphogenesis in the chicken embryo using a replication-defective retrovirus: I. Formation of the ventricular myocardium. Developmental dynamics : an official publication of the American Association of Anatomists. 1992 Academic Article GET IT
Times cited: 167
cDNA cloning and sequence comparisons of human and chicken muscle C-protein and 86kD protein. Symposia of the Society for Experimental Biology. 1992 Academic Article GET IT
Times cited: 13
In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species. Experimental cell research. 1991 Academic Article GET IT
Times cited: 114
Visualization of myosin exchange between synthetic thick filaments. Journal of muscle research and cell motility. 1991 Academic Article GET IT
Times cited: 10
Cell-free incorporation of newly synthesized myosin subunits into thick myofilaments. Journal of muscle research and cell motility. 1991 Academic Article GET IT
Times cited: 15
Molecular analysis of protein assembly in muscle development. Science (New York, N.Y.). 1991 Review GET IT
Times cited: 111
Post-translational incorporation of actin into myofibrils in vitro: evidence for isoform specificity. Cell motility and the cytoskeleton. 1991 Academic Article GET IT
Times cited: 17
Polarized release of enveloped viruses in the embryonic chick heart: demonstration of epithelial polarity in the presumptive myocardium. Developmental biology. 1990 Academic Article GET IT
Times cited: 24
Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: an intracellular member of the immunoglobulin superfamily. Proceedings of the National Academy of Sciences of the United States of America. 1990 Academic Article GET IT
Times cited: 120
Size and charge heterogeneity of C-protein isoforms in avian skeletal muscle. Expression of six different isoforms in chicken muscle. Journal of muscle research and cell motility. 1989 Academic Article GET IT
Times cited: 22
Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans. Proceedings of the National Academy of Sciences of the United States of America. 1989 Academic Article GET IT
Times cited: 50
Starvation leads to decreased levels of mRNA for myofibrillar proteins. The Journal of surgical research. 1989 Academic Article GET IT
Times cited: 18
Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins. The American journal of physiology. 1989 Academic Article GET IT
Times cited: 38
Diversity in expression of myosin heavy chain isoforms and M-band proteins in rat muscle spindles. Histochemistry. 1989 Academic Article GET IT
Times cited: 41
Posttranslational incorporation of contractile proteins into myofibrils in a cell-free system. The Journal of cell biology. 1988 Academic Article GET IT
Times cited: 21
Immunochemical analysis of protein isoforms in thick myofilaments of regenerating skeletal muscle. Developmental biology. 1987 Academic Article GET IT
Times cited: 42
Dynamic exchange of myosin molecules between thick filaments. Proceedings of the National Academy of Sciences of the United States of America. 1986 Academic Article GET IT
Times cited: 33
Myosin heavy chain expression in embryonic cardiac cell cultures. Developmental biology. 1986 Academic Article GET IT
Times cited: 21
Electron microscopy of C-protein molecules from chicken skeletal muscle. Journal of muscle research and cell motility. 1986 Academic Article GET IT
Times cited: 14
Axial arrangement of the myosin rod in vertebrate thick filaments: immunoelectron microscopy with a monoclonal antibody to light meromyosin. The Journal of cell biology. 1985 Academic Article GET IT
Times cited: 35
Analysis of the metal-induced conformational change in myosin with a monoclonal antibody to light chain two. Journal of molecular biology. 1985 Academic Article GET IT
Times cited: 20
Recombinant DNA approach for defining the primary structure of monoclonal antibody epitopes. The analysis of a conformation-specific antibody to myosin light chain 2. Journal of molecular biology. 1985 Academic Article GET IT
Times cited: 34
Monoclonal antibodies to desmin: evidence for stage-dependent intermediate filament immunoreactivity during cardiac and skeletal muscle development. Annals of the New York Academy of Sciences. 1985 Academic Article GET IT
Times cited: 24
Coexistence of fast-type and slow-type C-proteins in neonatal chicken breast muscle. Developmental biology. 1984 Academic Article GET IT
Times cited: 16
Heterogeneity of type 1 skeletal muscle fibers revealed by monoclonal antibody to slow myosin. Muscle & nerve. 1984 Academic Article GET IT
Times cited: 64
Immunocytochemical analysis of intermediate filaments in embryonic heart cells with monoclonal antibodies to desmin. The Journal of cell biology. 1984 Academic Article GET IT
Times cited: 77
Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies. The Journal of cell biology. 1984 Academic Article GET IT
Times cited: 65
Proximity of reactive lysyl residue to the antigenic site in rabbit skeletal myosin against the monoclonal antibody (MF-18) generated to chicken skeletal myosin. Journal of biochemistry. 1984 Academic Article GET IT
Times cited: 7
Immunochemical analysis of C-protein isoform transitions during the development of chicken skeletal muscle. Developmental biology. 1984 Academic Article GET IT
Times cited: 54
Analysis of population cytokinetics of chick myocardial cells in tissue culture. Developmental biology. 1983 Academic Article GET IT
Times cited: 26
Detection of desmin-containing intermediate filaments in cultured muscle and nonmuscle cells by immunoelectron microscopy. The Journal of cell biology. 1983 Academic Article GET IT
Times cited: 23
Characterization of the C-protein from posterior latissimus dorsi muscle of the adult chicken: heterogeneity within a single sarcomere. The Journal of cell biology. 1983 Academic Article GET IT
Times cited: 38
Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. The Journal of cell biology. 1982 Academic Article GET IT
Times cited: 796
Isoforms of C-protein in adult chicken skeletal muscle: detection with monoclonal antibodies. The Journal of cell biology. 1982 Academic Article GET IT
Times cited: 90
High resolution scanning electron microscopy of isolated and in situ cytoskeletal elements. The Journal of cell biology. 1979 Academic Article GET IT
Times cited: 41
Immunological studies of the embryonic muscle cell surface. Antiserum to the prefusion myoblast. The Journal of cell biology. 1979 Academic Article GET IT
Times cited: 20
Muscle development in vitro following X irradiation. Developmental biology. 1978 Academic Article GET IT
Times cited: 9
Mitochondrial development during myogenesis. Developmental biology. 1977 Academic Article GET IT
Times cited: 19
A fusion-promoting macromolecular factor in muscle conditioned medium. Experimental cell research. 1977 Academic Article GET IT
Times cited: 16
Myosin accumulation in mononucleated cells of chick muscle cultures. Developmental biology. 1976 Academic Article GET IT
Times cited: 52
Compositional studies of myofibrils from rabbit striated muscle. The Journal of cell biology. 1976 Academic Article GET IT
Times cited: 131
Removal of Z-lines and alpha-actinin from isolated myofibrils by a calcium-activated neutral protease. The Journal of biological chemistry. 1975 Academic Article GET IT
Times cited: 228
Scanning electron microscopy of nerve-muscle contacts in embryonic cell culture. Developmental biology. 1975 Academic Article GET IT
Times cited: 8
The correlation of DNA synthesis and DNA polymerase activity in the developing chick heart. Developmental biology. 1974 Academic Article GET IT
Times cited: 26
Scanning electron microscopy of cell aggregation: cardiac and mixed retina-cardiac cell suspensions. Developmental biology. 1974 Academic Article GET IT
Times cited: 20
The in vitro cell fusion of embryonic chick muscle without DNA synthesis. Developmental biology. 1974 Academic Article GET IT
Times cited: 57
Morphological and physiological evidence for the development of functional neuromuscular junctions in vitro. Developmental biology. 1973 Academic Article GET IT
Times cited: 35
A comparative study of three methods for the ultrastructural demonstration of glycogen in thin sections. Journal of cell science. 1971 Academic Article GET IT
Times cited: 39
Membrane modifications in nutritionally induced filamentous Escherichia coli B. The Journal of cell biology. 1970 Academic Article GET IT
Times cited: 17
The synthesis and assembly of myofibrils in embryonic muscle. Current topics in developmental biology. 1970 Review GET IT
Times cited: 121
The development of nerve-muscle junctions in monolayer cultures of embryonic spinal cord and skeletal muscle cells. The Journal of cell biology. 1969 Academic Article GET IT
Times cited: 30
The fine structure of embryonic chick skeletal muscle cells differentiated in vitro. The Journal of cell biology. 1967 Academic Article GET IT
Times cited: 92
The formation of multiple layers of membrane-like structures in Escherichia coli B. The Journal of cell biology. 1967 Academic Article GET IT
Times cited: 5
Origin of osteoclasts from mononuclear leucocytes in regenerating newt limbs. The Anatomical record. 1962 Academic Article GET IT
Times cited: 133
Origin of the blastema in regenerating limbs of the newt Triturus viridescens. An autoradiographic study using tritiated thymidine to follow cell proliferation and migration. Developmental biology. 1961 Academic Article GET IT
Times cited: 222

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Background

education and training

M.D., Cornell University Medical College 1961
B.A., Kenyon College 1957

Contact

full name

Donald Alan Fischman

primary email

fisch@med.cornell.edu

VIVO Weill Cornell Medical College

Donald Alan Fischman Professor Emeritus of Cell and Developmental Biology

Publications

selected publications

Background

education and training

Contact

full name

primary email