The Journal of cell biology

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KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.. 222. 2022
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components.. 220. 2021
Correction: Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.. 220. 2021
Correction: An early endosome-derived retrograde trafficking pathway promotes secretory granule maturation.. 220. 2021
Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication.. 219. 2020
Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1.. 219. 2020
An early endosome-derived retrograde trafficking pathway promotes secretory granule maturation.. 219. 2020
ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons.. 219. 2020
Insulin activates intracellular transport of lipid droplets to release triglycerides from the liver.. 218. 2019
A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling.. 218. 2019
XLF and H2AX function in series to promote replication fork stability.. 218. 2019
The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.. 218. 2019
Rsp5 Ubiquitin ligase-mediated quality control system clears membrane proteins mistargeted to the vacuole membrane.. 218. 2018
Membrane protein recycling from the vacuole/lysosome membrane.. 217. 2018
Correction: Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.. 217. 2017
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division.. 217. 2017
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.. 216. 2017
The VDAC2-BAK axis regulates peroxisomal membrane permeability.. 216. 2017
SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes.. 214. 2016
NBR1 enables autophagy-dependent focal adhesion turnover.. 212. 2016
Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins.. 211. 2015
Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein.. 210. 2015
Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation.. 206. 2014
A Nobel Prize for membrane traffic: vesicles find their journey's end.. 203. 2013
Local palmitoylation cycles define activity-regulated postsynaptic subdomains.. 202. 2013
Deacetylation of p53 induces autophagy by suppressing Bmf expression.. 201. 2013
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.. 199. 2012
Eisosome proteins assemble into a membrane scaffold.. 195. 2011
Spindle microtubules generate tension-dependent changes in the distribution of inner kinetochore proteins.. 193. 2011
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.. 192. 2011
Microtubule disruption targets HIF-1alpha mRNA to cytoplasmic P-bodies for translational repression.. 192. 2011
G1 arrest and differentiation can occur independently of Rb family function.. 191. 2010
Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis.. 191. 2010
Unconventional secretion of Acb1 is mediated by autophagosomes.. 188. 2010
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis.. 187. 2009
Pro-BDNF-induced synaptic depression and retraction at developing neuromuscular synapses.. 185. 2009
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.. 184. 2009
Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3.. 183. 2008
Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins.. 183. 2008
MTOC translocation modulates IS formation and controls sustained T cell signaling.. 182. 2008
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy.. 181. 2008
Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice.. 180. 2008
The mitochondrial respiratory chain is a modulator of apoptosis.. 179. 2007
Phosphatidylethanolamine critically supports internalization of cell-penetrating protein C inhibitor.. 179. 2007
An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells.. 177. 2007
A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium.. 176. 2007
New component of ESCRT-I regulates endosomal sorting complex assembly.. 175. 2006
eIF4E is a central node of an RNA regulon that governs cellular proliferation.. 175. 2006
Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis.. 175. 2006
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK.. 172. 2006
CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation.. 171. 2005
Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.. 171. 2005
Spines and neurite branches function as geometric attractors that enhance protein kinase C action.. 170. 2005
Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle.. 170. 2005
Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin.. 170. 2005
CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+.. 170. 2005
eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR.. 169. 2005
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.. 167. 2004
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling.. 167. 2004
DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.. 166. 2004
Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition.. 165. 2004
Ca(2+)(cyt) negatively regulates the initiation of oocyte maturation.. 165. 2004
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes.. 164. 2004
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.. 164. 2004
Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton.. 164. 2004
Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain.. 164. 2004
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.. 163. 2003
Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination.. 163. 2003
Vps27 recruits ESCRT machinery to endosomes during MVB sorting.. 162. 2003
Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.. 158. 2002
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.. 157. 2002
Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.. 156. 2002
Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry.. 156. 2002
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast.. 155. 2001
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells.. 155. 2001
The erbB2 gene is required for the development of terminally differentiated spinal cord oligodendrocytes.. 154. 2001
Head-to-tail oligomerization of calsequestrin: a novel mechanism for heterogeneous distribution of endoplasmic reticulum luminal proteins.. 154. 2001
Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport.. 153. 2001
Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis.. 153. 2001
CD44 is a major E-selectin ligand on human hematopoietic progenitor cells.. 153. 2001
Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.. 152. 2001
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis.. 151. 2000
Spatial sensing in fibroblasts mediated by 3' phosphoinositides.. 151. 2000
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion.. 151. 2000
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation.. 149. 2000
In situ biochemical demonstration that P-glycoprotein is a drug efflux pump with broad specificity.. 148. 2000
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis.. 148. 2000
Ezrin promotes morphogenesis of apical microvilli and basal infoldings in retinal pigment epithelium.. 147. 1999
Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways.. 146. 1999
A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein.. 145. 1999
Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails.. 144. 1999
Calreticulin is essential for cardiac development.. 144. 1999
Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin.. 144. 1999
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis.. 143. 1998
The cytoplasmic tail of rhodopsin acts as a novel apical sorting signal in polarized MDCK cells.. 142. 1998
Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.. 142. 1998
An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells.. 142. 1998
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.. 142. 1998
Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognition.. 142. 1998
Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.. 141. 1998
Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells.. 140. 1998
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells.. 140. 1998
Sphingomyelinase treatment induces ATP-independent endocytosis.. 140. 1998
Compartmentalized IgE receptor-mediated signal transduction in living cells.. 139. 1997
The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination.. 139. 1997
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells.. 139. 1997
Major histocompatibility complex class II compartments in human and mouse B lymphoblasts represent conventional endocytic compartments.. 139. 1997
Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.. 139. 1997
Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant.. 138. 1997
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.. 138. 1997
Regulation of calreticulin gene expression by calcium.. 138. 1997
Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line.. 138. 1997
Myosin II is involved in the production of constitutive transport vesicles from the TGN.. 138. 1997
Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.. 137. 1997
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products.. 137. 1997
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants.. 136. 1997
A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15.. 135. 1996
Calreticulin modulates cell adhesiveness via regulation of vinculin expression.. 135. 1996
Transferrin receptor containing the SDYQRL motif of TGN38 causes a reorganization of the recycling compartment but is not targeted to the TGN.. 135. 1996
Synaptic vesicle recycling in synapsin I knock-out mice.. 134. 1996
Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.. 133. 1996
Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells.. 133. 1996
Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions.. 132. 1996
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.. 132. 1996
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells.. 130. 1995
Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.. 130. 1995
Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes.. 130. 1995
Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells.. 130. 1995
Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment.. 129. 1995
A recombinant tail-less integrin beta 4 subunit disrupts hemidesmosomes, but does not suppress alpha 6 beta 4-mediated cell adhesion to laminins.. 129. 1995
Plasticity in epithelial cell phenotype: modulation by expression of different cadherin cell adhesion molecules.. 129. 1995
Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast.. 129. 1995
A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast.. 128. 1995
Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin.. 128. 1995
Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.. 128. 1995
Beta 2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor.. 127. 1994
Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis.. 127. 1994
Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells.. 127. 1994
Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae.. 127. 1994
Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast.. 127. 1994
The GPI anchor of cell-surface proteins is synthesized on the cytoplasmic face of the endoplasmic reticulum.. 127. 1994
CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.. 126. 1994
Yolk platelets in Xenopus oocytes maintain an acidic internal pH which may be essential for sodium accumulation.. 125. 1994
PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution.. 124. 1994
The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain.. 124. 1994
Axonal regulation of Schwann cell integrin expression suggests a role for alpha 6 beta 4 in myelination.. 123. 1993
Beta-very low density lipoprotein is sequestered in surface-connected tubules in mouse peritoneal macrophages.. 123. 1993
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion.. 123. 1993
The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif.. 123. 1993
The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected.. 122. 1993
Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin).. 122. 1993
Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer.. 121. 1993
Glycosylphosphatidylinositol-anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells.. 121. 1993
Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process.. 121. 1993
Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment.. 121. 1993
Apical polarization of N-CAM in retinal pigment epithelium is dependent on contact with the neural retina.. 121. 1993
Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion.. 120. 1993
Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor.. 120. 1993
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.. 120. 1993
Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells.. 120. 1993
GTP gamma S inhibits organelle transport along axonal microtubules.. 120. 1993
Apoptosis in metanephric development.. 119. 1992
In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae.. 119. 1992
Association of p60c-src with endosomal membranes in mammalian fibroblasts.. 118. 1992
Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes.. 117. 1992
The activity of cAMP-dependent protein kinase is required at a posttranslational level for induction of voltage-dependent sodium channels by peptide growth factors in PC12 cells.. 116. 1992
An endogenous MDCK lysosomal membrane glycoprotein is targeted basolaterally before delivery to lysosomes.. 115. 1991
The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages.. 115. 1991
An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells.. 115. 1991
Differences in the action and metabolism between retinol and retinoic acid in B lymphocytes.. 115. 1991
Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: differential expression of the amino-propeptide.. 114. 1991
Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant.. 114. 1991
Transfer of glycosyl-phosphatidylinositol membrane anchors to polypeptide acceptors in a cell-free system.. 114. 1991
Retinoic acid stimulates the differentiation of PC12 cells that are deficient in cAMP-dependent protein kinase.. 113. 1991
Microtubular organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells.. 113. 1991
Apical polarity of Na,K-ATPase in retinal pigment epithelium is linked to a reversal of the ankyrin-fodrin submembrane cytoskeleton.. 112. 1991
Mutagenesis of the human transferrin receptor: two cytoplasmic phenylalanines are required for efficient internalization and a second-site mutation is capable of reverting an internalization-defective phenotype.. 112. 1991
Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells.. 112. 1991
Attachment to fibronectin or vitronectin makes human neutrophil migration sensitive to alterations in cytosolic free calcium concentration.. 112. 1991
ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18).. 111. 1990
In vitro reconstitution of intercompartmental protein transport to the yeast vacuole.. 111. 1990
Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line.. 111. 1990
Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages.. 111. 1990
Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.. 111. 1990
Gene expression in visceral endoderm: a comparison of mutant and wild-type F9 embryonal carcinoma cell differentiation.. 110. 1990
Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells.. 110. 1990
Nerve growth factor and fibroblast growth factor regulate neurite outgrowth and gene expression in PC12 cells via both protein kinase C- and cAMP-independent mechanisms.. 110. 1990
Fc and C3bi receptors and the differentiation antigen BH2-Ag are randomly distributed in the plasma membrane of locomoting neutrophils.. 110. 1990
Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils.. 110. 1990
Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome.. 109. 1989
Polarized endocytosis by Madin-Darby canine kidney cells transfected with functional chicken liver glycoprotein receptor.. 109. 1989
A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells.. 109. 1989
Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells.. 109. 1989
Steady-state distribution and biogenesis of endogenous Madin-Darby canine kidney glycoproteins: evidence for intracellular sorting and polarized cell surface delivery.. 109. 1989
Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.. 109. 1989
Basic fibroblast growth factor is an extracellular matrix component required for supporting the proliferation of vascular endothelial cells and the differentiation of PC12 cells.. 109. 1989
Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex.. 109. 1989
Expression of fibroblast growth factor by F9 teratocarcinoma cells as a function of differentiation.. 108. 1989
The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.. 108. 1989
Selective anchoring in the specific plasma membrane domain: a role in epithelial cell polarity.. 107. 1988
Exocytosis of vacuolar apical compartment (VAC): a cell-cell contact controlled mechanism for the establishment of the apical plasma membrane domain in epithelial cells.. 107. 1988
Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting.. 107. 1988
Long-lasting and rapid calcium changes during mitosis.. 107. 1988
Posttranslational incorporation of contractile proteins into myofibrils in a cell-free system.. 107. 1988
A molecular defect in virally transformed muscle cells that cannot cluster acetylcholine receptors.. 106. 1988
Intracellular fusion of sequentially formed endocytic compartments.. 106. 1988
Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation.. 106. 1988
Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells.. 105. 1987
Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophages.. 105. 1987
Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells.. 105. 1987
Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release.. 105. 1987
Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor.. 105. 1987
Modulation of the expression of an apical plasma membrane protein of Madin-Darby canine kidney epithelial cells: cell-cell interactions control the appearance of a novel intracellular storage compartment.. 104. 1987
Formation of the apical pole of epithelial (Madin-Darby canine kidney) cells: polarity of an apical protein is independent of tight junctions while segregation of a basolateral marker requires cell-cell interactions.. 104. 1987
The large external domain is sufficient for the correct sorting of secreted or chimeric influenza virus hemagglutinins in polarized monkey kidney cells.. 104. 1987
Neurite outgrowth induced by an endothelial cell mitogen isolated from retina.. 103. 1986
Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.. 103. 1986
Microtubules and actin filaments are not critically involved in the biogenesis of epithelial cell surface polarity.. 102. 1986
Clustering, mobility, and triggering activity of small oligomers of immunoglobulin E on rat basophilic leukemia cells.. 102. 1986
Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization.. 102. 1986
The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal.. 102. 1986
Trophic effects of skeletal muscle extracts on ventral spinal cord neurons in vitro: separation of a protein with morphologic activity from proteins with cholinergic activity.. 101. 1985
Axial arrangement of the myosin rod in vertebrate thick filaments: immunoelectron microscopy with a monoclonal antibody to light meromyosin.. 101. 1985
Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme.. 100. 1985
Digital imaging fluorescence microscopy: spatial heterogeneity of photobleaching rate constants in individual cells.. 100. 1985
Legionella pneumophila inhibits acidification of its phagosome in human monocytes.. 99. 1984
Lipoprotein-heparin-fibronectin-denatured collagen complexes enhance cholesteryl ester accumulation in macrophages.. 99. 1984
Thyrotropin-releasing hormone-induced changes in intracellular [Ca2+] measured by microspectrofluorometry on individual quin2-loaded cells.. 99. 1984
Immunocytochemical analysis of intermediate filaments in embryonic heart cells with monoclonal antibodies to desmin.. 98. 1984
Studies on the development and maintenance of epithelial cell surface polarity with monoclonal antibodies.. 98. 1984
Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies.. 98. 1984
Viral glycoproteins destined for apical or basolateral plasma membrane domains traverse the same Golgi apparatus during their intracellular transport in doubly infected Madin-Darby canine kidney cells.. 98. 1984
Organization of acetylcholine receptor clusters in cultured rat myotubes is calcium dependent.. 98. 1984
Small oligomers of immunoglobulin E (IgE) cause large-scale clustering of IgE receptors on the surface of rat basophilic leukemia cells.. 98. 1984
Intracellular transport of influenza virus hemagglutinin to the apical surface of Madin-Darby canine kidney cells.. 98. 1984
Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules.. 97. 1983
Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line.. 97. 1983
Role of fibronectin as a growth factor for fibroblasts.. 97. 1983
Acidification of endocytic vesicles by an ATP-dependent proton pump.. 97. 1983
Assembly of enveloped viruses in Madin-Darby canine kidney cells: polarized budding from single attached cells and from clusters of cells in suspension.. 96. 1983
Detection of desmin-containing intermediate filaments in cultured muscle and nonmuscle cells by immunoelectron microscopy.. 96. 1983
Characterization of the C-protein from posterior latissimus dorsi muscle of the adult chicken: heterogeneity within a single sarcomere.. 96. 1983
Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.. 95. 1982
Molecular components of the signal sequence that function in the initiation of protein export.. 95. 1982
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.. 95. 1982
Isoforms of C-protein in adult chicken skeletal muscle: detection with monoclonal antibodies.. 95. 1982
Lipid monolayer-coated solid surfaces do not perturb the lateral motion and distribution of C3b receptors on neutrophils.. 94. 1982
The MDCK epithelial cell line expresses a cell surface antigen of the kidney distal tubule.. 93. 1982
Recovery of ribophorins and ribosomes in "inverted rough" vesicles derived from rat liver rough microsomes.. 93. 1982
Growth control in cultured 3T3 fibroblasts II. Molecular properties of a fraction enriched in growth inhibitory activity.. 92. 1982
Development of muscle fiber specialization in the rat hindlimb.. 90. 1981
Glycosylation does not determine segregation of viral envelope proteins in the plasma membrane of epithelial cells.. 89. 1981
A mechanism of protein localization: the signal hypothesis and bacteria.. 86. 1980
High resolution scanning electron microscopy of isolated and in situ cytoskeletal elements.. 83. 1979
Isolation of human platelet plasma membranes with polylysine beads.. 82. 1979
alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions.. 82. 1979
Immunological studies of the embryonic muscle cell surface. Antiserum to the prefusion myoblast.. 81. 1979
Spatial orientation of glycoproteins in membranes of rat liver rough microsomes. I. Localization of lectin-binding sites in microsomal membranes.. 78. 1978
Spatial orientation of glycoproteins in membranes of rat liver rough microsomes. II. Transmembrane disposition and characterization of glycoproteins.. 78. 1978
Flow cytofluorometric analysis of cell cycle distributions using propidium iodide. Properties of the method and mathematical analysis of the data.. 71. 1976
Compositional studies of myofibrils from rabbit striated muscle.. 68. 1976
Studies on isolated membranes of azurophil and specific granules from rabbit polymorphonuclear leukocytes.. 54. 1972
Isolation and biochemical characterization of nuclei from chick embryo liver.. 50. 1971
Radioautographic evidence for equatorial wall growth in a gram-positive bacterium. Segregation of choline-3H-labeled teichoic acid.. 47. 1970
Membrane modifications in nutritionally induced filamentous Escherichia coli B.. 45. 1970
The development of nerve-muscle junctions in monolayer cultures of embryonic spinal cord and skeletal muscle cells.. 43. 1969
Plasma membranes of the rat liver. Isolation and enzymatic characterization of a fraction rich in bile canaliculi.. 41. 1969
Fast and slow components in axonal transport of protein.. 38. 1968
The fine structure of embryonic chick skeletal muscle cells differentiated in vitro.. 35. 1967
Changes in the activity of acid hydrolases during renal reabsorption of lysozyme.. 35. 1967
The formation of multiple layers of membrane-like structures in Escherichia coli B.. 32. 1967
Correction: An early endosome-derived retrograde trafficking pathway promotes secretory granule maturation.. 221. 2022
Separating neuronal compartments gives clues as to local effect of ubiquitin conjugates in synaptogenesis. 2016
It takes two to tango to the melanosome. 2009
HIV-1 membrane fusion: targets of opportunity. 2000
The complexity of the serine glycine one-carbon pathway in cancer. 2020
Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases. 2017
The cell biology of vision. 2010
Journeys through the Golgi--taking stock in a new era. 2009
Cytokines in context. 1991

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