Choi, Augustine M. K.

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CEACAM6: A Novel Marker of Chronic Obstructive Pulmonary Disease Susceptibility?. American journal of respiratory and critical care medicine. 2023 Editorial Article GET IT
Retraction Notice to: mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation. Cell reports. 2023 Academic Article GET IT
Correction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3. Life science alliance. 2023 Academic Article GET IT
Mitochondria in Health, Disease, and Ageing. Physiological reviews. 2023 Review GET IT
IL-4 drastically decreases deuterosomal and multiciliated cells via alteration in progenitor cell differentiation. Allergy. 2023 Academic Article GET IT
UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis. The Journal of clinical investigation. 2023 Article GET IT
AMPK Activation: Respiratory Panacea?. American journal of respiratory cell and molecular biology. 2023 Editorial Article GET IT
Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. Molecular medicine (Cambridge, Mass.). 2023 Academic Article GET IT
Times cited: 1
Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. PLoS pathogens. 2022 Academic Article GET IT
Times cited: 6
Cell-Type-Specific Expression of Hyaluronan Synthases HAS2 and HAS3 Promotes Goblet Cell Hyperplasia in Allergic Airway Inflammation. American journal of respiratory cell and molecular biology. 2022 Academic Article GET IT
Times cited: 1
Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. medRxiv : the preprint server for health sciences. 2022 Article GET IT
Times cited: 1081
Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS. medRxiv : the preprint server for health sciences. 2022 Article GET IT
Times cited: 11
Serum proteomic profiling of rheumatoid arthritis-interstitial lung disease with a comparison to idiopathic pulmonary fibrosis. Thorax. 2022 Academic Article GET IT
Times cited: 2
Integrative metabolomic and proteomic signatures define clinical outcomes in severe COVID-19. iScience. 2022 Academic Article GET IT
Times cited: 17082
Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome. The American journal of pathology. 2022 Academic Article GET IT
Times cited: 11
Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice. Scientific reports. 2022 Academic Article GET IT
Times cited: 2
Conditional deletion of myeloid-specific mitofusin 2 but not mitofusin 1 promotes kidney fibrosis. Kidney international. 2022 Academic Article GET IT
Times cited: 4
Identification of Robust Protein Associations With COVID-19 Disease Based on Five Clinical Studies. Frontiers in immunology. 2022 Academic Article GET IT
Times cited: 10
A Comparative Analysis of the Respiratory Subscore of the Sequential Organ Failure Assessment Scoring System. Annals of the American Thoracic Society. 2021 Academic Article GET IT
Times cited: 8
The Saga of Necroptosis in Chronic Obstructive Pulmonary Disease Continues. American journal of respiratory and critical care medicine. 2021 Editorial Article GET IT
Association of circulating cell-free double-stranded DNA and metabolic derangements in idiopathic pulmonary fibrosis. Thorax. 2021 Academic Article GET IT
Autophagy in major human diseases. The EMBO journal. 2021 Review GET IT
Times cited: 318
Reversal of emphysema by restoration of pulmonary endothelial cells. The Journal of experimental medicine. 2021 Academic Article GET IT
Times cited: 20
Cytokine signatures of end organ injury in COVID-19. Scientific reports. 2021 Academic Article GET IT
Times cited: 22
Decreased IDO1-dependent tryptophan metabolism in aged lung during influenza. The European respiratory journal. 2021 Academic Article GET IT
Times cited: 5
Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort. Respiratory research. 2021 Academic Article GET IT
Times cited: 8
Effect of Neutropenic Critical Illness on Development and Prognosis of Acute Respiratory Distress Syndrome. American journal of respiratory and critical care medicine. 2021 Letter GET IT
Times cited: 4
CD44v3-Positive Intermediate Progenitor Cells Contribute to Airway Goblet Cell Hyperplasia. American journal of respiratory cell and molecular biology. 2021 Academic Article GET IT
Endogenous Carbon Monoxide Production and Diffusing Capacity of the Lung for Carbon Monoxide in Sepsis-Induced Acute Respiratory Distress Syndrome. Critical care explorations. 2020 Academic Article GET IT
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. The Journal of clinical investigation. 2020 Academic Article GET IT
Times cited: 4
MTOR suppresses autophagy-mediated production of IL25 in allergic airway inflammation. Thorax. 2020 Academic Article GET IT
Times cited: 5
Temporal trends of outcomes of neutropenic patients with ARDS enrolled in therapeutic clinical trials. Intensive care medicine. 2020 Letter GET IT
Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice. The European respiratory journal. 2020 Academic Article GET IT
Times cited: 8
N-Glycosylation Regulates Chitinase 3-like-1 and IL-13 Ligand Binding to IL-13 Receptor α2. American journal of respiratory cell and molecular biology. 2020 Academic Article GET IT
Times cited: 10
Weill Cornell Medicine. Academic medicine : journal of the Association of American Medical Colleges. 2020 Academic Article GET IT
Correction: Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2). The Journal of biological chemistry. 2020 Academic Article GET IT
DNA Methylation Is Predictive of Mortality in Current and Former Smokers. American journal of respiratory and critical care medicine. 2020 Academic Article GET IT
Times cited: 9
Autophagy in chronic lung disease. 2020 GET IT
Times cited: 1
Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort. JCI insight. 2020 Academic Article GET IT
Times cited: 24
Persistent severe acute respiratory distress syndrome for the prognostic enrichment of trials. PloS one. 2020 Academic Article GET IT
Times cited: 6
Biobanking and cryopreservation of human lung explants for omic analysis. The European respiratory journal. 2020 Academic Article GET IT
Times cited: 9
Apolipoprotein E and Periostin Are Potential Biomarkers of Nasal Mucosal Inflammation. A Parallel Approach of In Vitro and In Vivo Secretomes. American journal of respiratory cell and molecular biology. 2020 Academic Article GET IT
Times cited: 10
The authors reply. Critical care medicine. 2020 Letter GET IT
Eliminating Medical School Debt: A Dean and Geriatrician's View From Opposite Ends of the Training Pipeline. Annals of internal medicine. 2019 Academic Article GET IT
Times cited: 2
GLUT1-dependent glycolysis regulates exacerbation of fibrosis via AIM2 inflammasome activation. Thorax. 2019 Academic Article GET IT
Times cited: 32
Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis. JCI insight. 2019 Academic Article GET IT
Times cited: 75
Low Dose Carbon Monoxide Exposure in Idiopathic Pulmonary Fibrosis Produces a CO Signature Comprised of Oxidative Phosphorylation Genes. Scientific reports. 2019 Academic Article GET IT
Times cited: 10
Heteroplasmy concordance between mitochondrial DNA and RNA. Scientific reports. 2019 Academic Article GET IT
Times cited: 7
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis. Cells. 2019 Academic Article GET IT
Necroptosis: a crucial pathogenic mediator of human disease. JCI insight. 2019 Review GET IT
Times cited: 215
Circulating Mitochondrial DNA as Predictor of Mortality in Critically Ill Patients: A Systematic Review of Clinical Studies. Chest. 2019 Academic Article GET IT
Times cited: 24
Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome. Critical care medicine. 2019 Academic Article GET IT
Times cited: 57
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Nature communications. 2019 Academic Article GET IT
Times cited: 68
Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity. JCI insight. 2019 Academic Article GET IT
Times cited: 16
Shaping the Path for a Global Oncology Academic Career. JAMA oncology. 2019 Article GET IT
Times cited: 4
Objectively Measured Chronic Lung Injury on Chest CT. Chest. 2019 Academic Article GET IT
Times cited: 6
Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3. Life science alliance. 2019 Academic Article GET IT
Times cited: 21
Circulating cell death biomarker TRAIL is associated with increased organ dysfunction in sepsis. JCI insight. 2019 Academic Article GET IT
Times cited: 25
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. Science (New York, N.Y.). 2019 Academic Article GET IT
Times cited: 466
Integrins α_vβ₅ and α_vβ₆ Mediate IL-4-induced Collective Migration in Human Airway Epithelial Cells. American journal of respiratory cell and molecular biology. 2019 Academic Article GET IT
Times cited: 8
Diurnal Rhythms Spatially and Temporally Organize Autophagy. Cell reports. 2019 Academic Article GET IT
Times cited: 39
Plasma mitochondrial DNA and metabolomic alterations in severe critical illness. Critical care (London, England). 2018 Academic Article GET IT
Times cited: 26
A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS. JCI insight. 2018 Academic Article GET IT
Times cited: 63
Rapidly Improving ARDS in Therapeutic Randomized Controlled Trials. Chest. 2018 Academic Article GET IT
Times cited: 48
Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease. JCI insight. 2018 Academic Article GET IT
Times cited: 15
Laminin α1 is a genetic modifier of TGF-β1-stimulated pulmonary fibrosis. JCI insight. 2018 Academic Article GET IT
Times cited: 18
Determination of Early Immune Function in Sepsis and Its Influence on Organ Dysfunction. Is a More Pragmatic Outcome on the Horizon?. American journal of respiratory and critical care medicine. 2018 Editorial Article GET IT
Times cited: 1
Lipid Synthesis Is Required to Resolve Endoplasmic Reticulum Stress and Limit Fibrotic Responses in the Lung. American journal of respiratory cell and molecular biology. 2018 Academic Article GET IT
Times cited: 45
Circulating RIPK3 levels are associated with mortality and organ failure during critical illness. JCI insight. 2018 Academic Article GET IT
Times cited: 24
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction. JCI insight. 2018 Academic Article GET IT
Times cited: 95
Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort. Radiology. 2018 Academic Article GET IT
Times cited: 23
Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials. Journal of critical care. 2018 Academic Article GET IT
Times cited: 9
Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters. Critical care medicine. 2018 Academic Article GET IT
Times cited: 162
Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci. American journal of respiratory and critical care medicine. 2018 Academic Article GET IT
Times cited: 42
RIPK3 mediates pathogenesis of experimental ventilator-induced lung injury. JCI insight. 2018 Academic Article GET IT
Times cited: 48
Danger Signals in the ICU. Critical care medicine. 2018 Review GET IT
Times cited: 13
Dysbiosis of Inferior Turbinate Microbiota Is Associated with High Total IgE Levels in Patients with Allergic Rhinitis. Infection and immunity. 2018 Academic Article GET IT
Times cited: 34
A community approach to mortality prediction in sepsis via gene expression analysis. Nature communications. 2018 Academic Article GET IT
Times cited: 114
Association between acute respiratory disease events and the MUC5B promoter polymorphism in smokers. Thorax. 2018 Academic Article GET IT
Times cited: 8
Autophagy and inflammation in chronic respiratory disease. Autophagy. 2018 Review GET IT
Times cited: 254
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase. JCI insight. 2018 Academic Article GET IT
Times cited: 57
The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness. American journal of respiratory and critical care medicine. 2018 Review GET IT
Times cited: 28
Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 Academic Article GET IT
Times cited: 42
Plasma surfactant protein-D as a diagnostic biomarker for acute respiratory distress syndrome: validation in US and Korean cohorts. BMC pulmonary medicine. 2017 Academic Article GET IT
Times cited: 37
NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection. American journal of physiology. Lung cellular and molecular physiology. 2017 Academic Article GET IT
Times cited: 25
A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis. Chest. 2017 Academic Article GET IT
Times cited: 53
Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. Nature communications. 2017 Academic Article GET IT
Times cited: 18
NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B₄ Synthesis. American journal of respiratory and critical care medicine. 2017 Academic Article GET IT
Times cited: 102
Mitochondrial DNA in Sepsis. Current opinion in critical care. 2017 Review GET IT
Times cited: 48
Metabolome alterations in severe critical illness and vitamin D status. Critical care (London, England). 2017 Academic Article GET IT
Times cited: 29
Macrolides protect against Pseudomonas aeruginosa infection via inhibition of inflammasomes. American journal of physiology. Lung cellular and molecular physiology. 2017 Academic Article GET IT
Times cited: 15
Molecular definitions of autophagy and related processes. The EMBO journal. 2017 Review GET IT
Times cited: 1014
Clinical and Genetic Associations of Objectively Identified Interstitial Changes in Smokers. Chest. 2017 Academic Article GET IT
Times cited: 27
Glucose Transporter 1-Dependent Glycolysis Is Increased during Aging-Related Lung Fibrosis, and Phloretin Inhibits Lung Fibrosis. American journal of respiratory cell and molecular biology. 2017 Academic Article GET IT
Times cited: 73
Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit. Critical care (London, England). 2017 Academic Article GET IT
Times cited: 147
Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue. Scientific reports. 2017 Academic Article GET IT
Times cited: 61
Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction. American journal of respiratory cell and molecular biology. 2017 Academic Article GET IT
Times cited: 33
Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes. Critical care medicine. 2017 Academic Article GET IT
Times cited: 117
The Objective Identification and Quantification of Interstitial Lung Abnormalities in Smokers. Academic radiology. 2016 Academic Article GET IT
Times cited: 28
Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators. Critical care medicine. 2016 Academic Article GET IT
Times cited: 49
Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma. Scientific reports. 2016 Academic Article GET IT
Times cited: 45
DNA methylation profiling in human lung tissue identifies genes associated with COPD. Epigenetics. 2016 Academic Article GET IT
Times cited: 58
Enhanced autophagy in pulmonary endothelial cells on exposure to HIV-Tat and morphine: Role in HIV-related pulmonary arterial hypertension. Autophagy. 2016 Academic Article GET IT
Times cited: 34
Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation. American journal of respiratory cell and molecular biology. 2016 Academic Article GET IT
Times cited: 93
NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages. Nature medicine. 2016 Academic Article GET IT
Times cited: 218
Metabolites Associated With Malnutrition in the Intensive Care Unit Are Also Associated With 28-Day Mortality. JPEN. Journal of parenteral and enteral nutrition. 2016 Academic Article GET IT
Times cited: 25
A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin. American journal of respiratory and critical care medicine. 2016 Academic Article GET IT
Times cited: 87
SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages. Autophagy. 2016 Academic Article GET IT
Times cited: 180
The role of necroptosis in pulmonary diseases. Respiratory investigation. 2016 Review GET IT
Times cited: 22
Autophagy and Obesity-Related Lung Disease. American journal of respiratory cell and molecular biology. 2016 Review GET IT
Times cited: 19
Mitochondria in lung disease. The Journal of clinical investigation. 2016 Review GET IT
Times cited: 162
Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease. American journal of respiratory cell and molecular biology. 2016 Review GET IT
Times cited: 89
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nature medicine. 2016 Academic Article GET IT
Times cited: 163
Erratum. Autophagy. 2016 Article GET IT
Fatty acid synthesis and NLRP3-inflammasome. Oncotarget. 2015 Editorial Article GET IT
Times cited: 6
The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. American journal of respiratory cell and molecular biology. 2015 Academic Article GET IT
Times cited: 51
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia. American journal of physiology. Lung cellular and molecular physiology. 2015 Academic Article GET IT
Times cited: 26
Midkine: In the Middle of the Pathogenesis of Acute Respiratory Distress Syndrome-associated Lung Fibrosis?. American journal of respiratory and critical care medicine. 2015 Editorial Article GET IT
Times cited: 3
Impaired oxidative phosphorylation regulates necroptosis in human lung epithelial cells. Biochemical and biophysical research communications. 2015 Academic Article GET IT
Times cited: 16
mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation. Cell reports. 2015 Academic Article GET IT
Times cited: 277
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation. Translational research : the journal of laboratory and clinical medicine. 2015 Review GET IT
Times cited: 247
Detection of Rheumatoid Arthritis-Interstitial Lung Disease Is Enhanced by Serum Biomarkers. American journal of respiratory and critical care medicine. 2015 Academic Article GET IT
Times cited: 115
The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells. Biochemical and biophysical research communications. 2015 Academic Article GET IT
Times cited: 11
Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis. PloS one. 2015 Academic Article GET IT
Times cited: 131
Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages. American journal of physiology. Lung cellular and molecular physiology. 2015 Academic Article GET IT
Times cited: 55
UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis. The Journal of clinical investigation. 2015 Academic Article GET IT
Times cited: 193
Autophagy in lung disease pathogenesis and therapeutics. Redox biology. 2015 Academic Article GET IT
Times cited: 106
Emerging role of selective autophagy in human diseases. Frontiers in pharmacology. 2014 Review GET IT
Times cited: 75
Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. American journal of physiology. Lung cellular and molecular physiology. 2014 Academic Article GET IT
Times cited: 32
Circadian rhythm reprogramming during lung inflammation. Nature communications. 2014 Academic Article GET IT
Times cited: 119
Integrative "omic" analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes. American journal of respiratory and critical care medicine. 2014 Academic Article GET IT
Times cited: 79
Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2014 Academic Article GET IT
Times cited: 8
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. The Journal of clinical investigation. 2014 Academic Article GET IT
Times cited: 395
Molecular regulation of autophagy and its implications for metabolic diseases. Current opinion in clinical nutrition and metabolic care. 2014 Review GET IT
Times cited: 47
RETRACTED: Effect of early versus late or no tracheostomy on mortality of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis. The Lancet. Respiratory medicine. 2014 Academic Article GET IT
Times cited: 5
Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages. The Journal of infectious diseases. 2014 Academic Article GET IT
Times cited: 77
Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells. American journal of physiology. Lung cellular and molecular physiology. 2014 Academic Article GET IT
Times cited: 61
Epigenetics and the unfolded protein response in the lung: emerging role for microRNAs. American journal of respiratory and critical care medicine. 2014 Editorial Article GET IT
Times cited: 5
Metabolomic derangements are associated with mortality in critically ill adult patients. PloS one. 2014 Academic Article GET IT
Times cited: 103
Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation. PLoS medicine. 2013 Academic Article GET IT
Times cited: 305
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. Molecular cancer research : MCR. 2013 Academic Article GET IT
Times cited: 45
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. The Journal of clinical investigation. 2013 Academic Article GET IT
Times cited: 232
c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy. Circulation research. 2013 Academic Article GET IT
Times cited: 82
Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis. Antioxidants & redox signaling. 2013 Academic Article GET IT
Times cited: 96
Paneth cells as a site of origin for intestinal inflammation. Nature. 2013 Academic Article GET IT
Times cited: 532
Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease. Antioxidants & redox signaling. 2013 Review GET IT
Times cited: 76
Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress. Oxidative medicine and cellular longevity. 2013 Academic Article GET IT
Times cited: 118
Autophagy: An Integral Component of the Mammalian Stress Response. Journal of biochemical and pharmacological research. 2013 Academic Article GET IT
Autophagic flux and oxidative capacity of skeletal muscles during acute starvation. Autophagy. 2013 Academic Article GET IT
Times cited: 40
An integrated clinico-metabolomic model improves prediction of death in sepsis. Science translational medicine. 2013 Academic Article GET IT
Times cited: 324
Mitochondria: sensors and mediators of innate immune receptor signaling. Current opinion in microbiology. 2013 Review GET IT
Times cited: 50
Autophagy: a critical regulator of cellular metabolism and homeostasis. Molecules and cells. 2013 Review GET IT
Times cited: 239
Inhaled carbon monoxide accelerates resolution of inflammation via unique proresolving mediator-heme oxygenase-1 circuits. Journal of immunology (Baltimore, Md. : 1950). 2013 Academic Article GET IT
Times cited: 96
Deacetylation of p53 induces autophagy by suppressing Bmf expression. The Journal of cell biology. 2013 Academic Article GET IT
Times cited: 37
Menin mediates epigenetic regulation via histone H3 lysine 9 methylation. Cell death & disease. 2013 Academic Article GET IT
Times cited: 42
p62 sequestosome 1/light chain 3b complex confers cytoprotection on lung epithelial cells after hyperoxia. American journal of respiratory cell and molecular biology. 2013 Academic Article GET IT
Times cited: 35
Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells. Genomics. 2013 Academic Article GET IT
Times cited: 36
Carbon monoxide: present and future indications for a medical gas. The Korean journal of internal medicine. 2013 Review GET IT
Times cited: 72
Autophagy in human health and disease. The New England journal of medicine. 2013 Review GET IT
Times cited: 837
Haem oxygenase-1 overexpression alters intracellular iron distribution. The Biochemical journal. 2013 Academic Article GET IT
Times cited: 24
The emerging importance of autophagy in pulmonary diseases. Chest. 2012 Review GET IT
Times cited: 100
TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema. American journal of physiology. Lung cellular and molecular physiology. 2012 Academic Article GET IT
Times cited: 61
Regulation and functional significance of autophagy in respiratory cell biology and disease. American journal of respiratory cell and molecular biology. 2012 Review GET IT
Times cited: 47
Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 68
Retinoic acid-related orphan receptor-α is induced in the setting of DNA damage and promotes pulmonary emphysema. American journal of respiratory and critical care medicine. 2012 Academic Article GET IT
Times cited: 33
Heme Oxygenase-1/CO as protective mediators in cigarette smoke- induced lung cell injury and chronic obstructive pulmonary disease. Current pharmaceutical biotechnology. 2012 Review GET IT
Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2). The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 62
Inflammasome-regulated cytokines are critical mediators of acute lung injury. American journal of respiratory and critical care medicine. 2012 Academic Article GET IT
Times cited: 420
Regenerative pulmonary medicine: potential and promise, pitfalls and challenges. European journal of clinical investigation. 2012 Review GET IT
Times cited: 19
Autophagic proteins: new facets of the oxygen paradox. Autophagy. 2012 Article GET IT
Times cited: 32
Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis. American journal of physiology. Lung cellular and molecular physiology. 2012 Academic Article GET IT
Times cited: 36
Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. American journal of respiratory and critical care medicine. 2012 Academic Article GET IT
Times cited: 109
Genetically manipulated mouse models of lung disease: potential and pitfalls. American journal of physiology. Lung cellular and molecular physiology. 2011 Review GET IT
Times cited: 51
Mitochondria: commanders of innate immunity and disease?. Current opinion in immunology. 2011 Review GET IT
Times cited: 64
Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. Human molecular genetics. 2011 Academic Article GET IT
Times cited: 118
Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death. American journal of respiratory cell and molecular biology. 2011 Academic Article GET IT
Times cited: 96
Nucleotide-binding oligomerization domain protein 2 deficiency enhances neointimal formation in response to vascular injury. Arteriosclerosis, thrombosis, and vascular biology. 2011 Academic Article GET IT
Times cited: 16
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell. 2011 Academic Article GET IT
Times cited: 592
Autophagy: a core cellular process with emerging links to pulmonary disease. American journal of respiratory and critical care medicine. 2011 Review GET IT
Times cited: 59
Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy. 2011 Academic Article GET IT
Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy. 2011 Academic Article GET IT
Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells. Medical gas research. 2011 Academic Article GET IT
Times cited: 15
Deadly triplex: smoke, autophagy and apoptosis. Autophagy. 2011 Academic Article GET IT
Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation. American journal of respiratory cell and molecular biology. 2011 Academic Article GET IT
Times cited: 105
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis. Free radical biology & medicine. 2011 Academic Article GET IT
Times cited: 40
Isolation of mouse respiratory epithelial cells and exposure to experimental cigarette smoke at air liquid interface. Journal of visualized experiments : JoVE. 2011 Academic Article GET IT
Times cited: 44
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nature immunology. 2010 Academic Article GET IT
Times cited: 2156
Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine. Current drug targets. 2010 Review GET IT
Times cited: 82
TSLP polymorphisms are associated with asthma in a sex-specific fashion. Allergy. 2010 Academic Article GET IT
Times cited: 99
Bronchoprovocation testing in asthma: effect on exhaled monoxides. Journal of breath research. 2010 Academic Article GET IT
Times cited: 5
Caveolin-1: a critical regulator of lung injury. American journal of physiology. Lung cellular and molecular physiology. 2010 Review GET IT
Times cited: 99
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 293
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. American journal of respiratory and critical care medicine. 2010 Academic Article GET IT
Times cited: 166
Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. Expert review of respiratory medicine. 2010 Review GET IT
Times cited: 61
Evaluation of inhaled carbon monoxide as an anti-inflammatory therapy in a nonhuman primate model of lung inflammation. American journal of physiology. Lung cellular and molecular physiology. 2010 Academic Article GET IT
Times cited: 35
Inhaled hydrogen sulfide protects against ventilator-induced lung injury. Anesthesiology. 2010 Academic Article GET IT
Times cited: 90
Autophagy in the lung. Proceedings of the American Thoracic Society. 2010 Review GET IT
Times cited: 101
Autophagy in vascular disease. Proceedings of the American Thoracic Society. 2010 Review GET IT
Times cited: 82
Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation. Circulation. 2009 Academic Article GET IT
Times cited: 156
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. American journal of human genetics. 2009 Academic Article GET IT
Times cited: 125
The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease. PloS one. 2009 Academic Article GET IT
Times cited: 46
Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. The Journal of biological chemistry. 2009 Academic Article GET IT
Times cited: 415
The fibrotic phenotype induced by IGFBP-5 is regulated by MAPK activation and egr-1-dependent and -independent mechanisms. The American journal of pathology. 2009 Academic Article GET IT
Times cited: 57
Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. American journal of respiratory cell and molecular biology. 2009 Review GET IT
Times cited: 245
Carbon monoxide prevents ventilator-induced lung injury via caveolin-1. Critical care medicine. 2009 Academic Article GET IT
Times cited: 60
Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells. American journal of physiology. Lung cellular and molecular physiology. 2009 Academic Article GET IT
Times cited: 135
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free radical biology & medicine. 2009 Review GET IT
Times cited: 158
The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 174
Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism?. Autophagy. 2009 Academic Article GET IT
Times cited: 55
Discovery of the gene signature for acute lung injury in patients with sepsis. Physiological genomics. 2009 Academic Article GET IT
Times cited: 54
Carbon monoxide modulates alpha-smooth muscle actin and small proline rich-1a expression in fibrosis. American journal of respiratory cell and molecular biology. 2008 Academic Article GET IT
Times cited: 21
Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation. Blood. 2008 Academic Article GET IT
Times cited: 102
Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy. 2008 Academic Article GET IT
Times cited: 174
Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. Translational research : the journal of laboratory and clinical medicine. 2008 Academic Article GET IT
Times cited: 51
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PloS one. 2008 Academic Article GET IT
Times cited: 377
Network analysis of temporal effects of intermittent and sustained hypoxia on rat lungs. Physiological genomics. 2008 Academic Article GET IT
Times cited: 34
Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008 Academic Article GET IT
Times cited: 33
CX3CL1 up-regulation is associated with recruitment of CX3CR1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema. The American journal of pathology. 2008 Academic Article GET IT
Times cited: 57
Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts. Kidney international. 2008 Academic Article GET IT
Times cited: 63
Carbon monoxide ameliorates renal cold ischemia-reperfusion injury with an upregulation of vascular endothelial growth factor by activation of hypoxia-inducible factor. Transplantation. 2008 Academic Article GET IT
Times cited: 59
Non-invasive measurements of exhaled NO and CO associated with methacholine responses in mice. Respiratory research. 2008 Academic Article GET IT
Times cited: 15
Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). 2008 Academic Article GET IT
Times cited: 44
Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1. American journal of respiratory and critical care medicine. 2008 Academic Article GET IT
Times cited: 100
Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1. American journal of respiratory cell and molecular biology. 2008 Academic Article GET IT
Times cited: 64
Gene expression profiling in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. 2008 Editorial Article GET IT
Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury. PloS one. 2008 Academic Article GET IT
Times cited: 77
Inhaled CO in the treatment of acute lung injury. American journal of physiology. Lung cellular and molecular physiology. 2008 Editorial Article GET IT
Times cited: 5
Identifying targets for COPD treatment through gene expression analyses. International journal of chronic obstructive pulmonary disease. 2008 Review GET IT
Times cited: 34
Inducing hypoxemia in healthy humans: a method for intermittently lowering arterial blood oxygenation during physiological studies. Wilderness & environmental medicine. 2008 Letter GET IT
Nitric oxide-deficiency regulates hepatic heme oxygenase-1. Nitric oxide : biology and chemistry. 2007 Academic Article GET IT
Times cited: 17
Functional significance of apoptosis in chronic obstructive pulmonary disease. COPD. 2007 Review GET IT
Times cited: 70
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system. Antioxidants & redox signaling. 2007 Review GET IT
Times cited: 91
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2007 Review GET IT
Carbon monoxide in sepsis. Antioxidants & redox signaling. 2007 Review GET IT
Times cited: 59
A new road to induce heme oxygenase-1 expression by carbon monoxide. Circulation research. 2007 Editorial Article GET IT
Times cited: 5
Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study. Respiratory research. 2007 Academic Article GET IT
Times cited: 49
Carbon monoxide protects rat lung transplants from ischemia-reperfusion injury via a mechanism involving p38 MAPK pathway. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2007 Academic Article GET IT
Times cited: 89
Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis. Journal of immunology (Baltimore, Md. : 1950). 2007 Academic Article GET IT
Times cited: 127
MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. American journal of physiology. Lung cellular and molecular physiology. 2007 Academic Article GET IT
Times cited: 68
FLIP inhibits endothelial cell apoptosis during hyperoxia by suppressing Bax. Free radical biology & medicine. 2007 Academic Article GET IT
Times cited: 21
Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans. Translational research : the journal of laboratory and clinical medicine. 2007 Academic Article GET IT
Mechanisms of cell death in oxidative stress. Antioxidants & redox signaling. 2007 Review GET IT
Times cited: 864
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. The Journal of experimental medicine. 2006 Academic Article GET IT
Times cited: 327
Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 170
Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts. American journal of respiratory cell and molecular biology. 2006 Academic Article GET IT
Times cited: 64
Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration. The American journal of pathology. 2006 Academic Article GET IT
Times cited: 67
Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. American journal of respiratory cell and molecular biology. 2006 Academic Article GET IT
Times cited: 196
Heat-shock proteins: new keys to the development of cytoprotective therapies. Expert opinion on therapeutic targets. 2006 Review GET IT
Times cited: 62
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. The Journal of experimental medicine. 2006 Academic Article GET IT
Times cited: 320
Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis. Arthritis and rheumatism. 2006 Academic Article GET IT
Times cited: 43
Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts. Surgery. 2006 Academic Article GET IT
Times cited: 73
Ex vivo application of carbon monoxide in University of Wisconsin solution to prevent intestinal cold ischemia/reperfusion injury. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2006 Academic Article GET IT
Times cited: 80
Protective effect of carbon monoxide in transplantation. Journal of cellular and molecular medicine. 2006 Review GET IT
Times cited: 112
Comparative SAGE analysis of the response to hypoxia in human pulmonary and aortic endothelial cells. Physiological genomics. 2006 Academic Article GET IT
Times cited: 13
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiological reviews. 2006 Review GET IT
Times cited: 1765
Therapeutic applications of carbon monoxide in lung disease. Current opinion in pharmacology. 2006 Review GET IT
Times cited: 49
Gene expression profiling of target genes in ventilator-induced lung injury. Physiological genomics. 2006 Academic Article GET IT
Times cited: 82
CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2. American journal of respiratory cell and molecular biology. 2006 Academic Article GET IT
Times cited: 95
Heart allograft protection with low-dose carbon monoxide inhalation: effects on inflammatory mediators and alloreactive T-cell responses. Transplantation. 2006 Academic Article GET IT
Times cited: 64
A Peptide with anti-transglutaminase activity decreases lipopolysaccharide-induced lung inflammation in mice. Experimental lung research. 2006 Academic Article GET IT
Times cited: 13
CO as a cellular signaling molecule. Annual review of pharmacology and toxicology. 2006 Review GET IT
Times cited: 341
Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway. American journal of respiratory cell and molecular biology. 2005 Academic Article GET IT
Times cited: 130
Phosphatidylinositol 3-kinase/Akt pathway mediates heme oxygenase-1 regulation by lipopolysaccharide. Cellular and molecular biology (Noisy-le-Grand, France). 2005 Academic Article GET IT
Times cited: 20
Biliverdin administration protects against endotoxin-induced acute lung injury in rats. American journal of physiology. Lung cellular and molecular physiology. 2005 Academic Article GET IT
Times cited: 164
Low-dose carbon monoxide inhalation prevents development of chronic allograft nephropathy. American journal of physiology. Renal physiology. 2005 Academic Article GET IT
Times cited: 56
Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. Journal of immunology (Baltimore, Md. : 1950). 2005 Academic Article GET IT
Times cited: 125
Carbon monoxide inhibits IL-17-induced IL-6 production through the MAPK pathway in human pulmonary epithelial cells. American journal of physiology. Lung cellular and molecular physiology. 2005 Academic Article GET IT
Times cited: 29
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 108
Alterations in nitric oxide and cytokine production with airway inflammation in the absence of IL-10. Journal of immunology (Baltimore, Md. : 1950). 2005 Academic Article GET IT
Times cited: 14
Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells. American journal of respiratory cell and molecular biology. 2005 Academic Article GET IT
Times cited: 38
"Therapeutic" carbon monoxide may be a reality soon. American journal of respiratory and critical care medicine. 2005 Letter GET IT
"Therapeutic" carbon monoxide may be toxic. American journal of respiratory and critical care medicine. 2005 Letter GET IT
Times cited: 21
Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus. Critical care medicine. 2005 Academic Article GET IT
Times cited: 64
FLIP protects against hypoxia/reoxygenation-induced endothelial cell apoptosis by inhibiting Bax activation. Molecular and cellular biology. 2005 Academic Article GET IT
Times cited: 37
Heme oxygenase-1: from bench to bedside. American journal of respiratory and critical care medicine. 2005 Review GET IT
Times cited: 159
Global gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Discovery medicine. 2005 Academic Article GET IT
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2005 Academic Article GET IT
Times cited: 190
Carbon monoxide suppresses bleomycin-induced lung fibrosis. The American journal of pathology. 2005 Academic Article GET IT
Times cited: 101
Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. Antioxidants & redox signaling. 2005 Review GET IT
Times cited: 185
Enhanced nitric oxide production associated with airway hyporesponsiveness in the absence of IL-10. American journal of physiology. Lung cellular and molecular physiology. 2004 Academic Article GET IT
Times cited: 8
Bcl-XL disrupts death-inducing signal complex formation in plasma membrane induced by hypoxia/reoxygenation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2004 Academic Article GET IT
Times cited: 41
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 290
Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells. The Journal of biological chemistry. 2004 Academic Article GET IT
Times cited: 66
Caveolae compartmentalization of heme oxygenase-1 in endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2004 Academic Article GET IT
Times cited: 154
Genome-wide analysis of the endothelial transcriptome under short-term chronic hypoxia. Physiological genomics. 2004 Academic Article GET IT
Times cited: 34
Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury. American journal of respiratory and critical care medicine. 2004 Academic Article GET IT
Times cited: 121
Carbon monoxide: to boldly go where NO has gone before. Science's STKE : signal transduction knowledge environment. 2004 Review GET IT
Times cited: 113
Haem oxygenase-1 expression is diminished in alveolar macrophages of patients with COPD. The European respiratory journal. 2004 Letter GET IT
Times cited: 25
Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2004 Academic Article GET IT
Times cited: 157
Carbon monoxide inhibits T lymphocyte proliferation via caspase-dependent pathway. Journal of immunology (Baltimore, Md. : 1950). 2004 Academic Article GET IT
Times cited: 99
Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. The Journal of experimental medicine. 2003 Academic Article GET IT
Times cited: 191
MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury. The American journal of pathology. 2003 Academic Article GET IT
Times cited: 179
Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 68
Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. The American journal of pathology. 2003 Academic Article GET IT
Times cited: 185
Cotransfection of heme oxygenase-1 prevents the acute inflammation elicited by a second adenovirus. Gene therapy. 2003 Academic Article GET IT
Times cited: 13
Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility. Gut. 2003 Academic Article GET IT
Times cited: 94
Heme oxygenase-1 and carbon monoxide in pulmonary medicine. Respiratory research. 2003 Review GET IT
Times cited: 119
Low-dose carbon monoxide reduces airway hyperresponsiveness in mice. American journal of physiology. Lung cellular and molecular physiology. 2003 Academic Article GET IT
Times cited: 53
Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts. Surgery. 2003 Academic Article GET IT
Times cited: 77
Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 334
Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects. The American journal of pathology. 2003 Academic Article GET IT
Times cited: 201
Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts. American journal of respiratory cell and molecular biology. 2003 Academic Article GET IT
Times cited: 116
Controlled gene delivery system based on thermosensitive biodegradable hydrogel. Pharmaceutical research. 2003 Academic Article GET IT
Times cited: 126
Necrotic cell death in response to oxidant stress involves the activation of the apoptogenic caspase-8/bid pathway. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 112
Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice. American journal of physiology. Lung cellular and molecular physiology. 2003 Academic Article GET IT
Times cited: 35
Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. American journal of respiratory cell and molecular biology. 2003 Academic Article GET IT
Times cited: 171
Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine. Gastroenterology. 2003 Academic Article GET IT
Times cited: 127
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nature medicine. 2003 Academic Article GET IT
Times cited: 426
Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages. American journal of respiratory cell and molecular biology. 2002 Academic Article GET IT
Times cited: 121
Transcriptional regulation of the HO-1 gene in cultured macrophages exposed to model airborne particulate matter. American journal of physiology. Lung cellular and molecular physiology. 2002 Academic Article GET IT
Times cited: 21
Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. American journal of respiratory cell and molecular biology. 2002 Academic Article GET IT
Times cited: 107
TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells. American journal of physiology. Lung cellular and molecular physiology. 2002 Academic Article GET IT
Times cited: 94
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 245
Depletion of pulmonary EC-SOD after exposure to hyperoxia. American journal of physiology. Lung cellular and molecular physiology. 2002 Academic Article GET IT
Times cited: 89
Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury. American journal of physiology. Lung cellular and molecular physiology. 2002 Academic Article GET IT
Times cited: 96
Regulation of IL-1beta -induced GM-CSF production in human airway smooth muscle cells by carbon monoxide. American journal of physiology. Lung cellular and molecular physiology. 2002 Academic Article GET IT
Times cited: 39
Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress. Antioxidants & redox signaling. 2002 Review GET IT
Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells. Antioxidants & redox signaling. 2002 Academic Article GET IT
Times cited: 52
Heme oxygenase-1: the "emerging molecule" has arrived. American journal of respiratory cell and molecular biology. 2002 Review GET IT
Times cited: 435
Differential modulation by exogenous carbon monoxide of TNF-alpha stimulated mitogen-activated protein kinases in rat pulmonary artery endothelial cells. Antioxidants & redox signaling. 2002 Academic Article GET IT
Emerging role of carbon monoxide in physiologic and pathophysiologic states. Antioxidants & redox signaling. 2002 Editorial Article GET IT
Heme oxygenase-1 protects the heart. Circulation research. 2001 Editorial Article GET IT
Times cited: 27
Carbon monoxide attenuates aeroallergen-induced inflammation in mice. American journal of physiology. Lung cellular and molecular physiology. 2001 Academic Article GET IT
Times cited: 133
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 358
Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. Journal of immunology (Baltimore, Md. : 1950). 2001 Academic Article GET IT
Times cited: 417
Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: role of the p38 MAPK pathway. American journal of physiology. Renal physiology. 2001 Academic Article GET IT
Times cited: 130
Carbon monoxide-dependent signaling. Critical care medicine. 2001 Academic Article GET IT
Heme oxygenase: colors of defense against cellular stress. American journal of physiology. Lung cellular and molecular physiology. 2000 Review GET IT
Times cited: 807
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. The Journal of experimental medicine. 2000 Academic Article GET IT
Times cited: 881
Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages. American journal of physiology. Lung cellular and molecular physiology. 2000 Academic Article GET IT
Times cited: 64
Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 355
AP-1 and STAT mediate hyperoxia-induced gene transcription of heme oxygenase-1. American journal of physiology. Lung cellular and molecular physiology. 2000 Academic Article GET IT
Times cited: 94
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nature medicine. 2000 Academic Article GET IT
Times cited: 1746
Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts. American journal of physiology. Lung cellular and molecular physiology. 2000 Academic Article GET IT
Times cited: 263
Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells. The American journal of physiology. 1999 Academic Article GET IT
Times cited: 62
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 1014
Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. The American journal of physiology. 1999 Academic Article GET IT
Times cited: 112
Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 93
Carbon monoxide provides protection against hyperoxic lung injury. The American journal of physiology. 1999 Academic Article GET IT
Times cited: 430
Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. The Journal of clinical investigation. 1999 Academic Article GET IT
Times cited: 470
Induction of heme oxygenase-1 with hemoglobin depresses vasoreactivity in rat aorta. Journal of vascular research. 1999 Academic Article GET IT
Times cited: 11
Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1998 Academic Article GET IT
Times cited: 87
Induction of apoptosis by particulate matter: role of TNF-alpha and MAPK. The American journal of physiology. 1998 Academic Article GET IT
Times cited: 88
Expression of heme oxygenase-1 can determine cardiac xenograft survival. Nature medicine. 1998 Academic Article GET IT
Times cited: 551
Pulmonary apoptosis in aged and oxygen-tolerant rats exposed to hyperoxia. The American journal of physiology. 1998 Academic Article GET IT
Times cited: 51
Transcriptional activation of the HO-1 gene by lipopolysaccharide is mediated by 5' distal enhancers: role of reactive oxygen intermediates and AP-1. American journal of respiratory cell and molecular biology. 1998 Academic Article GET IT
Times cited: 124
Role of oxidants in influenza virus-induced gene expression. The American journal of physiology. 1998 Academic Article GET IT
Times cited: 71
Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide. The American journal of physiology. 1997 Academic Article GET IT
Times cited: 180
Hyaluronan fragments induce nitric-oxide synthase in murine macrophages through a nuclear factor kappaB-dependent mechanism. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 253
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 619
Mechanism of hemoglobin-induced protection against endotoxemia in rats: a ferritin-independent pathway. The American journal of physiology. 1997 Academic Article GET IT
Times cited: 70
Alpha-2 adrenoceptor blockade protects rats against lipopolysaccharide. American journal of respiratory and critical care medicine. 1996 Academic Article GET IT
Times cited: 26
Urethan anesthesia protects rats against lethal endotoxemia and reduces TNF-alpha release. Journal of applied physiology (Bethesda, Md. : 1985). 1996 Academic Article GET IT
Times cited: 31
Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 330
Oxidant stress responses in influenza virus pneumonia: gene expression and transcription factor activation. The American journal of physiology. 1996 Academic Article GET IT
Times cited: 91
Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. American journal of respiratory cell and molecular biology. 1996 Review GET IT
Times cited: 976
Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. American journal of respiratory cell and molecular biology. 1996 Academic Article GET IT
Times cited: 191
Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. American journal of respiratory cell and molecular biology. 1995 Academic Article GET IT
Times cited: 285
Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). Molecular medicine (Cambridge, Mass.). 1995 Academic Article GET IT
Times cited: 257
Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. American journal of respiratory cell and molecular biology. 1995 Academic Article GET IT
Times cited: 220
Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: reduced AP-1 activation and collagenase gene expression. Journal of cellular physiology. 1995 Academic Article GET IT
Times cited: 29
Molecular responses to hyperoxia in vivo: relationship to increased tolerance in aged rats. American journal of respiratory cell and molecular biology. 1995 Academic Article GET IT
Times cited: 74
Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer. The Journal of biological chemistry. 1995 Academic Article GET IT
Times cited: 192
The oxidative stress response. New horizons (Baltimore, Md.). 1995 Review GET IT
Times cited: 152
Calcium mediates expression of stress-response genes in prostaglandin A2-induced growth arrest. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1994 Academic Article GET IT
Times cited: 48
Influenza virus induces expression of antioxidant genes in human epithelial cells. Free radical biology & medicine. 1994 Academic Article GET IT
Times cited: 73
Messenger RNA levels of lung extracellular matrix proteins during ozone exposure. Lung. 1994 Academic Article GET IT
Times cited: 20
Influenza virus A infection induces interleukin-8 gene expression in human airway epithelial cells. FEBS letters. 1992 Academic Article GET IT
Times cited: 114
Differential extracellular matrix gene expression by fibroblasts during their proliferative life span in vitro and at senescence. Journal of cellular physiology. 1992 Academic Article GET IT
Times cited: 31
Induction of HSP70 gene expression by the antiproliferative prostaglandin PGA2: a growth-dependent response mediated by activation of heat shock transcription factor. Molecular and cellular biology. 1992 Academic Article GET IT
Times cited: 63
Cell growth inhibition by prostaglandin A2 results in elevated expression of gadd153 mRNA. Experimental cell research. 1992 Academic Article GET IT
Times cited: 43

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Research

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Co-investigator Network

Funding awarded

Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers awarded by National Heart, Lung, & Blood Institute Principal Investigator 2021 - 2026
A Phase 1b Study of Inhaled CO for the Treatment of Sepsis-Induced ARDS awarded by National Heart, Lung, & Blood Institute Principal Investigator 2020 - 2025
missing activity Principal Investigator 2019 - 2022
A Phase II Study of Inhaled CO for the Treatment of ARDS awarded by United States Department of Defense Principal Investigator 2018 - 2022
missing activity Principal Investigator 2017 - 2022
missing activity Principal Investigator 2017 - 2021

Impact of Heightened UPR Activation on Inflammasome Responses to Influenza and Secondary Streptococcus Pneumoniae Infection in Aged Lung awarded by National Institute on Aging Co-Investigator 2018 - 2023
Multidisciplinary Approach Training in Respiratory Research awarded by National Heart, Lung, & Blood Institute Co-Investigator 2018 - 2023
missing activity Co-Investigator 2018 - 2022

Multidisciplinary Approach Training in Respiratory Research awarded by National Heart, Lung, & Blood Institute Key Personnel 2023 - 2028
The Pulmonary Lymphatics in Inflammation and Disease awarded by National Heart, Lung, & Blood Institute Key Personnel 2019 - 2024
Iron and Renal Fibrosis in Juvenile Chronic Kidney Disease awarded by National Institute of Diabetes & Digestive & Kidney Diseases Key Personnel 2018 - 2023
G3BP1 Suppresses SPOP Ubiquitin Ligase to Promote Prostate Tumorigenesis awarded by National Cancer Institute Key Personnel 2018 - 2022
GLUT1-Dependent Glycolysis Regulates Age-Susceptible Lung Fibrosis awarded by National Heart, Lung, & Blood Institute Key Personnel 2017 - 2022
missing activity Key Personnel 2017 - 2022

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Background

education and training

A.M., Harvard University 2007
M.D., University of Louisville School of Medicine 1984
B.S., University of Kentucky 1980

Contact

full name

Augustine M. K. Choi

VIVO Weill Cornell Medical College

Augustine M. K. Choi Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name