Gudas, Lorraine

Publications

Sort by

Co-Author Network

selected publications

NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma. Cancer biology & therapy. 2023 Academic Article GET IT
Vitamin A and retinoid signaling in the kidneys. Pharmacology & therapeutics. 2023 Review GET IT
Novel genetically engineered mouse models for clear cell renal cell carcinoma. Scientific reports. 2023 Academic Article GET IT
The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer. Frontiers in cell and developmental biology. 2023 Academic Article GET IT
Times cited: 239
Transcriptomic analysis predicts the risk of progression of premalignant lesions in human tongue. Discover. Oncology. 2023 Academic Article GET IT
Times cited: 67
Clinical and molecular significance of the RNA m⁶A methyltransferase complex in prostate cancer. Frontiers in genetics. 2023 Academic Article GET IT
Times cited: 220
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer. Cancers. 2022 Academic Article GET IT
Times cited: 90
Retinoid metabolism: new insights. Journal of molecular endocrinology. 2022 Review GET IT
Times cited: 6
Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer. Frontiers in endocrinology. 2022 Review GET IT
Times cited: 72
Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR). Molecular carcinogenesis. 2022 Academic Article GET IT
Times cited: 2
Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse. Pharmacology. 2022 Academic Article GET IT
The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy. Molecular oncology. 2022 Academic Article GET IT
Times cited: 4
Retinoids in the Pathogenesis and Treatment of Liver Diseases. Nutrients. 2022 Review GET IT
Times cited: 4
All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism. Frontiers in oncology. 2022 Academic Article GET IT
Times cited: 21
Pancreatic Ductal Adenocarcinoma: New Insights into the Actions of Vitamin A. Oncology research and treatment. 2022 Review GET IT
Times cited: 2
Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury. Frontiers in pharmacology. 2022 Academic Article GET IT
Times cited: 118
EZH2 knockout in oral cavity basal epithelia causes more invasive squamous cell carcinomas. Carcinogenesis. 2021 Academic Article GET IT
Times cited: 1
Mitochondrial Ndufa4l2 Enhances Deposition of Lipids and Expression of Ca9 in the TRACK Model of Early Clear Cell Renal Cell Carcinoma. Frontiers in oncology. 2021 Academic Article GET IT
Times cited: 242
A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes. BioFactors (Oxford, England). 2021 Academic Article GET IT
Times cited: 1
A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease. The Journal of biological chemistry. 2021 Academic Article GET IT
Times cited: 4
Synthetic Retinoids Beyond Cancer Therapy. Annual review of pharmacology and toxicology. 2021 Review GET IT
Times cited: 6
A Retinoic Acid Receptor β ₂ Agonist Improves Cardiac Function in a Heart Failure Model. The Journal of pharmacology and experimental therapeutics. 2021 Academic Article GET IT
Times cited: 11
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease. Frontiers in pharmacology. 2021 Academic Article GET IT
Times cited: 42
Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma. Carcinogenesis. 2020 Academic Article GET IT
Times cited: 10
The Effect of Ethanol Consumption on Composition and Morphology of Femur Cortical Bone in Wild-Type and ALDH2*2-Homozygous Mice. Calcified tissue international. 2020 Academic Article GET IT
Times cited: 3
Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase. Biochimica et biophysica acta. Molecular basis of disease. 2020 Academic Article GET IT
Times cited: 1
Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells. Molecular oncology. 2020 Academic Article GET IT
Times cited: 6
Doxycycline-induced exogenous Bmi-1 expression enhances tumor formation in a murine model of oral squamous cell carcinoma. Cancer biology & therapy. 2020 Academic Article GET IT
Times cited: 3
Correction: An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency. The Journal of biological chemistry. 2020 Academic Article GET IT
All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL). European journal of haematology. 2020 Academic Article GET IT
Times cited: 20
NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma. Investigational new drugs. 2020 Academic Article GET IT
Times cited: 8
Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma. Translational oncology. 2019 Academic Article GET IT
Times cited: 20
Modification of stem cell states by alcohol and acetaldehyde. Chemico-biological interactions. 2019 Review GET IT
Times cited: 5
Validation of risk factors for recurrence of renal cell carcinoma: Results from a large single-institution series. PloS one. 2019 Academic Article GET IT
Times cited: 8
Different Effects of Knockouts in ALDH2 and ACSS2 on Embryonic Stem Cell Differentiation. Alcoholism, clinical and experimental research. 2019 Academic Article GET IT
Times cited: 4
Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells. PloS one. 2019 Academic Article GET IT
Times cited: 13
Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ. The Journal of biological chemistry. 2019 Academic Article GET IT
Times cited: 13
Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease. PloS one. 2019 Academic Article GET IT
Times cited: 9
Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy. Methods in molecular biology (Clifton, N.J.). 2019 Academic Article GET IT
Times cited: 1
CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation. Journal of molecular biology. 2018 Academic Article GET IT
Times cited: 5
Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor β2 Agonist. The Journal of pharmacology and experimental therapeutics. 2018 Academic Article GET IT
Times cited: 11
A Retinoic Acid β₂-Receptor Agonist Exerts Cardioprotective Effects. The Journal of pharmacology and experimental therapeutics. 2018 Academic Article GET IT
Times cited: 8
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction. JCI insight. 2018 Academic Article GET IT
Times cited: 95
Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells. The Journal of biological chemistry. 2018 Academic Article GET IT
Times cited: 13
Detection of E2F-DNA Complexes Using Chromatin Immunoprecipitation Assays. Methods in molecular biology (Clifton, N.J.). 2018 Academic Article GET IT
OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation. Molecular cell. 2016 Academic Article GET IT
Times cited: 51
A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease. Journal of molecular medicine (Berlin, Germany). 2016 Academic Article GET IT
Times cited: 34
Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 37
Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis. Diabetes, obesity & metabolism. 2015 Academic Article GET IT
Times cited: 33
MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators. Oncotarget. 2015 Academic Article GET IT
Times cited: 41
Obesity Leads to Tissue, but not Serum Vitamin A Deficiency. Scientific reports. 2015 Academic Article GET IT
Times cited: 69
The Tale of Two Hypoxia-Inducible Factors in Renal Cell Carcinoma. European urology. 2015 Editorial Article GET IT
Times cited: 7
Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology. Oncotarget. 2015 Academic Article GET IT
Times cited: 23
Identification of Ethanol and 4-Nitroquinoline-1-Oxide Induced Epigenetic and Oxidative Stress Markers During Oral Cavity Carcinogenesis. Alcoholism, clinical and experimental research. 2015 Academic Article GET IT
Times cited: 23
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation. Experimental hematology. 2015 Academic Article GET IT
Times cited: 44
Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma. PloS one. 2015 Academic Article GET IT
Times cited: 25
Mesoscale nanoparticles selectively target the renal proximal tubule epithelium. Nano letters. 2015 Academic Article GET IT
Times cited: 103
Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model. Oncotarget. 2015 Academic Article GET IT
Times cited: 9
Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome. Molecular cancer research : MCR. 2015 Academic Article GET IT
Times cited: 19
Vitamin A: a missing link in diabetes?. Diabetes management (London, England). 2015 Academic Article GET IT
An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency. The Journal of biological chemistry. 2014 Academic Article GET IT
Times cited: 22
Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass. The Journal of biological chemistry. 2014 Academic Article GET IT
Times cited: 70
Altered histone mark deposition and DNA methylation at homeobox genes in human oral squamous cell carcinoma. Journal of cellular physiology. 2014 Academic Article GET IT
Times cited: 31
Retinoic acid suppresses the canonical Wnt signaling pathway in embryonic stem cells and activates the noncanonical Wnt signaling pathway. Stem cells (Dayton, Ohio). 2014 Academic Article GET IT
Times cited: 41
The role of HIF1α in renal cell carcinoma tumorigenesis. Journal of molecular medicine (Berlin, Germany). 2014 Review GET IT
Times cited: 69
Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 33
Crossing the barrier: STRA6 in epidermal differentiation. The Journal of investigative dermatology. 2014 Comment GET IT
Times cited: 2
Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells. The Journal of biological chemistry. 2014 Academic Article GET IT
Times cited: 59
Retinoid receptor signaling and autophagy in acute promyelocytic leukemia. Experimental cell research. 2014 Review GET IT
Times cited: 32
The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes. Sub-cellular biochemistry. 2014 Review GET IT
Times cited: 39
Expression of cyclin d1 and its association with disease characteristics in bladder cancer. Anticancer research. 2013 Academic Article GET IT
Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells. Experimental cell research. 2013 Academic Article GET IT
Times cited: 23
Retinoids induce stem cell differentiation via epigenetic changes. Seminars in cell & developmental biology. 2013 Review GET IT
Times cited: 64
Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 9
The molecular features of tongue epithelium treated with the carcinogen 4-nitroquinoline-1-oxide and alcohol as a model for HNSCC. Carcinogenesis. 2013 Academic Article GET IT
Times cited: 43
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation. Experimental cell research. 2013 Academic Article GET IT
Times cited: 23
Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer. Anticancer research. 2013 Academic Article GET IT
Times cited: 107
Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene. Nucleic acids research. 2013 Academic Article GET IT
Times cited: 37
Estrogen receptor-β expression and pharmacological targeting in bladder cancer. Oncology reports. 2013 Academic Article GET IT
Times cited: 30
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells. Experimental cell research. 2013 Academic Article GET IT
Times cited: 39
Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells. Journal of cellular physiology. 2013 Academic Article GET IT
Times cited: 37
CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia. Cell cycle (Georgetown, Tex.). 2013 Academic Article GET IT
Times cited: 718
Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis. Cancer research. 2013 Academic Article GET IT
Times cited: 36
Basal stem cells contribute to squamous cell carcinomas in the oral cavity. Carcinogenesis. 2013 Academic Article GET IT
Times cited: 23
The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer. Molecular oncology. 2013 Academic Article GET IT
Times cited: 76
RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells. Journal of cell science. 2012 Academic Article GET IT
Times cited: 49
Polycomb repressive complex 2 impedes intestinal cell terminal differentiation. Journal of cell science. 2012 Academic Article GET IT
Times cited: 39
The androgen receptor and stem cell pathways in prostate and bladder cancers (review). International journal of oncology. 2011 Review GET IT
Times cited: 29
Epigenetic regulation by RARα maintains ligand-independent transcriptional activity. Nucleic acids research. 2011 Academic Article GET IT
Times cited: 43
Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α. Cancer research. 2011 Academic Article GET IT
Times cited: 77
Emerging roles for retinoids in regeneration and differentiation in normal and disease states. Biochimica et biophysica acta. 2011 Review GET IT
Times cited: 120
Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression. Developmental biology. 2011 Academic Article GET IT
Times cited: 14
Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer. Molecular carcinogenesis. 2011 Academic Article GET IT
Times cited: 190
RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells. Journal of cellular physiology. 2011 Academic Article GET IT
Times cited: 23
Retinoids regulate stem cell differentiation. Journal of cellular physiology. 2011 Review GET IT
Times cited: 292
Clinical trial update and novel therapeutic approaches for metastatic prostate cancer. Current medicinal chemistry. 2011 Review GET IT
Times cited: 18
Retinoids, retinoic acid receptors, and cancer. Annual review of pathology. 2011 Review GET IT
Times cited: 453
Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 79
Induction of murine embryonic stem cell differentiation by medicinal plant extracts. Experimental cell research. 2010 Academic Article GET IT
Times cited: 21
Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals. Chest. 2010 Academic Article GET IT
Times cited: 42
Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells. Journal of cellular physiology. 2010 Academic Article GET IT
Times cited: 16
Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies. Cancer biology & therapy. 2010 Academic Article GET IT
Times cited: 18
Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 69
The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice. Regenerative medicine. 2010 Academic Article GET IT
Times cited: 29
Epimorphic regeneration approach to tissue replacement in adult mammals. Proceedings of the National Academy of Sciences of the United States of America. 2009 Academic Article GET IT
Times cited: 129
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Cancer prevention research (Philadelphia, Pa.). 2009 Academic Article GET IT
Times cited: 38
Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice. The Journal of nutritional biochemistry. 2009 Academic Article GET IT
Times cited: 8
Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells. Journal of cellular physiology. 2009 Academic Article GET IT
Times cited: 6
Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem cells and development. 2009 Review GET IT
Times cited: 332
Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation. Developmental dynamics : an official publication of the American Association of Anatomists. 2009 Academic Article GET IT
Times cited: 54
Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen. Cancer biology & therapy. 2009 Academic Article GET IT
Times cited: 12
Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model. Biochemical pharmacology. 2009 Academic Article GET IT
Times cited: 32
The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells. Journal of cellular biochemistry. 2009 Academic Article GET IT
Times cited: 13
Retinol saturase promotes adipogenesis and is downregulated in obesity. Proceedings of the National Academy of Sciences of the United States of America. 2009 Academic Article GET IT
Times cited: 72
Chemoattractant activity of degradation products of fetal and adult skin extracellular matrix for keratinocyte progenitor cells. Journal of tissue engineering and regenerative medicine. 2008 Academic Article GET IT
Times cited: 102
Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment. Cancer biology & therapy. 2008 Academic Article GET IT
Times cited: 34
Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons. Journal of neuroscience research. 2008 Academic Article GET IT
Times cited: 32
Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene. The international journal of biochemistry & cell biology. 2008 Academic Article GET IT
Times cited: 24
Retinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cells. Experimental hematology. 2008 Academic Article GET IT
Times cited: 10
Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet. Biochemical pharmacology. 2008 Academic Article GET IT
Times cited: 31
Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells. Journal of molecular biology. 2008 Academic Article GET IT
Times cited: 19
Overexpression of COUP-TF1 in murine embryonic stem cells reduces retinoic acid-associated growth arrest and increases extraembryonic endoderm gene expression. Differentiation; research in biological diversity. 2008 Academic Article GET IT
Times cited: 27
CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid. Developmental biology. 2007 Academic Article GET IT
Times cited: 38
Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells. Biochemical pharmacology. 2007 Academic Article GET IT
Times cited: 50
LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol. Molecular and cellular endocrinology. 2007 Academic Article GET IT
Times cited: 17
Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements. The Journal of biological chemistry. 2007 Academic Article GET IT
Times cited: 62
Phase 1/2 clinical trial of interferon alpha2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma. Journal of immunotherapy (Hagerstown, Md. : 1997). 2007 Academic Article GET IT
Times cited: 40
Overexpression of CRABPI in suprabasal keratinocytes enhances the proliferation of epidermal basal keratinocytes in mouse skin topically treated with all-trans retinoic acid. Experimental cell research. 2007 Academic Article GET IT
Times cited: 13
Diverse actions of retinoid receptors in cancer prevention and treatment. Differentiation; research in biological diversity. 2007 Review GET IT
Times cited: 159
Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells. Journal of molecular biology. 2007 Academic Article GET IT
Times cited: 106
The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures. Molecular carcinogenesis. 2006 Academic Article GET IT
Times cited: 56
Reduced lecithin:retinol acyltransferase expression in human breast cancer. International journal of oncology. 2006 Academic Article GET IT
Times cited: 9
Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid. Journal of lipid research. 2006 Academic Article GET IT
Times cited: 14
Stem cells, differentiation and cancer: mentors, colleagues and academic administration. Cancer biology & therapy. 2006 Academic Article GET IT
Structure elucidation of retinoids in biological samples using postsource decay laser desorption/ionization mass spectrometry after high-performance liquid chromatography separation. Analytical chemistry. 2006 Academic Article GET IT
Times cited: 6
Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder. Clinical cancer research : an official journal of the American Association for Cancer Research. 2005 Academic Article GET IT
Times cited: 170
Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma. Carcinogenesis. 2005 Academic Article GET IT
Times cited: 26
Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency. The Journal of biological chemistry. 2005 Academic Article GET IT
Times cited: 155
Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model. Clinical cancer research : an official journal of the American Association for Cancer Research. 2005 Academic Article GET IT
Times cited: 67
Retinoid receptor mRNA expression profiles in human bladder cancer specimens. International journal of oncology. 2005 Academic Article GET IT
Times cited: 11
Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells. Molecular cancer therapeutics. 2005 Academic Article GET IT
Times cited: 72
Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal. The Journal of biological chemistry. 2005 Academic Article GET IT
Times cited: 61
Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer. Urology. 2004 Academic Article GET IT
Times cited: 154
Reduced lecithin: retinol acyltransferase expression correlates with increased pathologic tumor stage in bladder cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 Academic Article GET IT
Times cited: 28
Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells. Experimental cell research. 2004 Academic Article GET IT
Times cited: 29
Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. Journal of cellular physiology. 2004 Academic Article GET IT
Times cited: 42
Differential regulation of laminin b1 transgene expression in the neonatal and adult mouse brain. Neuroscience. 2004 Academic Article GET IT
Times cited: 17
Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 Academic Article GET IT
Times cited: 284
Retinoic acid receptor-mediated induction of ABCA1 in macrophages. Molecular and cellular biology. 2003 Academic Article GET IT
Times cited: 118
Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney. Clinical cancer research : an official journal of the American Association for Cancer Research. 2003 Academic Article GET IT
Times cited: 21
Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells. Molecular cancer research : MCR. 2003 Academic Article GET IT
Times cited: 55
Homozygous deletion of the CRABPI gene in AB1 embryonic stem cells results in increased CRABPII gene expression and decreased intracellular retinoic acid concentration. Archives of biochemistry and biophysics. 2003 Academic Article GET IT
Times cited: 24
Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Developmental dynamics : an official publication of the American Association of Anatomists. 2003 Academic Article GET IT
Times cited: 31
Retinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines. Journal of cellular physiology. 2002 Academic Article GET IT
Times cited: 19
Retinoic acid induces parietal endoderm but not primitive endoderm and visceral endoderm differentiation in F9 teratocarcinoma stem cells with a targeted deletion of the Rex-1 (Zfp-42) gene. Molecular and cellular endocrinology. 2002 Academic Article GET IT
Times cited: 54
Phase I trial of interferon alpha2b and liposome-encapsulated all-trans retinoic acid in the treatment of patients with advanced renal cell carcinoma. Cancer. 2002 Academic Article GET IT
Times cited: 19
Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene. 2002 Academic Article GET IT
Times cited: 14
Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens. Cancer research. 2002 Academic Article GET IT
Times cited: 56
Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice. Developmental dynamics : an official publication of the American Association of Anatomists. 2002 Academic Article GET IT
Times cited: 56
retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. Cancer research. 2002 Academic Article GET IT
Times cited: 69
cis-acting DNA regulatory elements, including the retinoic acid response element, are required for tissue specific laminin B1 promoter/lacZ expression in transgenic mice. Mechanisms of development. 2001 Academic Article GET IT
Times cited: 14
Reduced levels of retinyl esters and vitamin A in human renal cancers. Cancer research. 2001 Academic Article GET IT
Times cited: 44
Follicle-stimulating hormone and leukemia inhibitory factor regulate Sertoli cell retinol metabolism. Endocrinology. 2001 Academic Article GET IT
Times cited: 11
Esterification of all-trans-retinol in normal human epithelial cell strains and carcinoma lines from oral cavity, skin and breast: reduced expression of lecithin:retinol acyltransferase in carcinoma lines. Carcinogenesis. 2000 Academic Article GET IT
Times cited: 57
Molecular cloning and analysis of a group of genes differentially expressed in cells which overexpress the Hoxa-1 homeobox gene. Experimental cell research. 2000 Academic Article GET IT
Times cited: 18
Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region. Molecular and cellular endocrinology. 2000 Academic Article GET IT
Times cited: 47
Transcriptional regulation of the cellular retinoic acid binding protein I gene in F9 teratocarcinoma cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 2000 Academic Article GET IT
Times cited: 14
Molecular cloning of a novel retinoic acid-responsive gene, HA1R-62, which is also up-regulated in Hoxa-1-overexpressing cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 2000 Academic Article GET IT
Times cited: 8
Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 1999 Academic Article GET IT
Times cited: 56
Prevention of cancer in the next millennium: Report of the Chemoprevention Working Group to the American Association for Cancer Research. Cancer research. 1999 Review GET IT
Times cited: 167
The targeted disruption of both alleles of RARbeta(2) in F9 cells results in the loss of retinoic acid-associated growth arrest. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 111
Synthesis of a novel C-nucleoside, 2-amino-7-(2-deoxy-beta-D-erythro- pentofuranosyl)-3H,5H-pyrrolo-[3,2-d]pyrimidin-4-one (2'-deoxy-9-deazaguanosine). Nucleosides & nucleotides. 1999 Academic Article GET IT
Times cited: 14
The murine Hoxb1 3' RAIDR5 enhancer contains multiple regulatory elements. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1998 Academic Article GET IT
Times cited: 7
Characterization of genes which exhibit reduced expression during the retinoic acid-induced differentiation of F9 teratocarcinoma cells: involvement of cyclin D3 in RA-mediated growth arrest. Molecular and cellular endocrinology. 1998 Academic Article GET IT
Times cited: 47
A conserved retinoic acid responsive element in the murine Hoxb-1 gene is required for expression in the developing gut. Development (Cambridge, England). 1998 Academic Article GET IT
Times cited: 106
4-Oxoretinol, a metabolite of retinol in the human promyelocytic leukemia cell line NB4, induces cell growth arrest and granulocytic differentiation. Cancer research. 1998 Academic Article GET IT
Times cited: 14
Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site. Molecular and cellular biology. 1998 Academic Article GET IT
Times cited: 219
An evolutionary conserved element is essential for somite and adjacent mesenchymal expression of the Hoxa1 gene. Developmental dynamics : an official publication of the American Association of Anatomists. 1998 Academic Article GET IT
Times cited: 25
Metabolism of all-trans-retinol in normal human cell strains and squamous cell carcinoma (SCC) lines from the oral cavity and skin: reduced esterification of retinol in SCC lines. Cancer research. 1998 Academic Article GET IT
Times cited: 43
Regulation of the laminin beta 1 (LAMB1), retinoic acid receptor beta, and bone morphogenetic protein 2 genes in mutant F9 teratocarcinoma cell lines partially deficient in cyclic AMP-dependent protein kinase activity. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1997 Academic Article GET IT
Times cited: 9
Sequences 5' of the basement membrane laminin beta 1 chain gene (LAMB1) direct the expression of beta-galactosidase during development of the mouse testis and ovary. Differentiation; research in biological diversity. 1997 Academic Article GET IT
Times cited: 9
Human breast cancer cells and normal mammary epithelial cells: retinol metabolism and growth inhibition by the retinol metabolite 4-oxoretinol. Cancer research. 1997 Academic Article GET IT
Times cited: 54
Sensitivity to jerky gene dosage underlies epileptic seizures in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1997 Academic Article GET IT
Times cited: 27
The CRABP I gene contains two separable, redundant regulatory regions active in neural tissues in transgenic mouse embryos. Developmental dynamics : an official publication of the American Association of Anatomists. 1997 Academic Article GET IT
Times cited: 16
Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 145
FGF-2, BMP-2, and BMP-4 regulate retinoid binding proteins and receptors in 3T3 cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1996 Academic Article GET IT
Times cited: 16
An analysis of retinoic acid-induced gene expression and metabolism in AB1 embryonic stem cells. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 49
4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 98
Murine laminin B1 gene regulation during the retinoic acid- and dibutyryl cyclic AMP-induced differentiation of embryonic F9 teratocarcinoma stem cells. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 33
Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types. Proceedings of the National Academy of Sciences of the United States of America. 1995 Academic Article GET IT
Times cited: 93
Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism. Molecular and cellular biology. 1995 Academic Article GET IT
Times cited: 157
The roles of retinoids in vertebrate development. Annual review of biochemistry. 1995 Review GET IT
Times cited: 272
Localization of PDGF A and PDGFR alpha mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells. Mechanisms of development. 1994 Academic Article GET IT
Times cited: 49
Vitamin A, differentiation and cancer. Current opinion in cell biology. 1994 Review GET IT
Times cited: 141
Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. Development (Cambridge, England). 1994 Academic Article GET IT
Times cited: 161
Retinoic acid and homeobox gene regulation. Current opinion in genetics & development. 1994 Review GET IT
Times cited: 82
Conversion of anterior limb bud cells to ZPA signaling cells in vitro and in vivo. Developmental biology. 1994 Academic Article GET IT
Times cited: 22
Enzymatic conversion of retinaldehyde to retinoic acid by cloned murine cytosolic and mitochondrial aldehyde dehydrogenases. Molecular pharmacology. 1994 Academic Article GET IT
Times cited: 29
Xenopus laevis cellular retinoic acid-binding protein: temporal and spatial expression pattern during early embryogenesis. Mechanisms of development. 1994 Academic Article GET IT
Times cited: 19
Retinoids and vertebrate development. The Journal of biological chemistry. 1994 Review GET IT
Times cited: 307
Activation of keratin 19 gene expression by a 3' enhancer containing an AP1 site. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 40
Differences in the pharmacokinetic properties of orally administered all-trans-retinoic acid and 9-cis-retinoic acid in the plasma of nude mice. Drug metabolism and disposition: the biological fate of chemicals. 1994 Academic Article GET IT
Times cited: 57
Loss of retinoic acid receptor gamma function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment. Proceedings of the National Academy of Sciences of the United States of America. 1993 Academic Article GET IT
Times cited: 141
Changing patterns of the retinoic acid system in the developing retina. Developmental biology. 1993 Academic Article GET IT
Times cited: 133
Retinoic acid fails to induce expression of Hox genes in differentiation-defective murine embryonal carcinoma cells carrying a mutant gene for alpha retinoic acid receptor. Differentiation; research in biological diversity. 1993 Academic Article GET IT
Times cited: 24
Report of group C of the American Cancer Society Research Workshop on Cancer and Nutrition: panel on cell and organ culture studies. Cancer research. 1993 Review GET IT
An octamer motif contributes to the expression of the retinoic acid-regulated zinc finger gene Rex-1 (Zfp-42) in F9 teratocarcinoma cells. Molecular and cellular biology. 1993 Academic Article GET IT
Times cited: 55
Time course of induction of metabolism of all-trans-retinoic acid and the up-regulation of cellular retinoic acid-binding protein. Cancer research. 1993 Academic Article GET IT
Times cited: 79
The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells. The Journal of biological chemistry. 1992 Academic Article GET IT
Times cited: 234
Identification of a retinoic acid responsive enhancer 3' of the murine homeobox gene Hox-1.6. Mechanisms of development. 1992 Academic Article GET IT
Times cited: 237
Retinoids, retinoid-responsive genes, cell differentiation, and cancer. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1992 Review GET IT
Times cited: 172
The location and expression of fibroblast growth factor (FGF) in F9 visceral and parietal embryonic cells after retinoic acid-induced differentiation. Differentiation; research in biological diversity. 1992 Academic Article GET IT
Times cited: 5
Thrombomodulin gene regulation by cAMP and retinoic acid in F9 embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 1992 Academic Article GET IT
Times cited: 49
Bone morphogenetic proteins-2 and -4 are involved in the retinoic acid-induced differentiation of embryonal carcinoma cells. Molecular biology of the cell. 1992 Academic Article GET IT
Times cited: 68
Mouse F9 teratocarcinoma stem cells expressing the stably transfected homeobox gene Hox 1.6 exhibit an altered morphology. Gene expression. 1992 Academic Article GET IT
Times cited: 9
Variable expression of retinoic acid receptor (RAR beta) mRNA in human oral and epidermal keratinocytes; relation to keratin 19 expression and keratinization potential. Differentiation; research in biological diversity. 1991 Academic Article GET IT
Times cited: 60
Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes. Development (Cambridge, England). 1991 Academic Article GET IT
Times cited: 229
Abnormal expression of retinoic acid receptors and keratin 19 by human oral and epidermal squamous cell carcinoma cell lines. Cancer research. 1991 Academic Article GET IT
Times cited: 218
A retinoic acid-inducible mRNA from F9 teratocarcinoma cells encodes a novel protease inhibitor homolog. The Journal of biological chemistry. 1991 Article GET IT
Times cited: 2
The oncofetal gene Pem encodes a homeodomain and is regulated in primordial and pre-muscle stem cells. Mechanisms of development. 1991 Academic Article GET IT
Times cited: 39
The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element. The EMBO journal. 1991 Academic Article GET IT
Times cited: 122
Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells. The Journal of cell biology. 1991 Academic Article GET IT
Times cited: 300
A retinoic acid-inducible mRNA from F9 teratocarcinoma cells encodes a novel protease inhibitor homologue. The Journal of biological chemistry. 1990 Academic Article GET IT
Times cited: 40
Gene expression in visceral endoderm: a comparison of mutant and wild-type F9 embryonal carcinoma cell differentiation. The Journal of cell biology. 1990 Academic Article GET IT
Times cited: 32
Molecular mechanisms of retinoid action. American journal of respiratory cell and molecular biology. 1990 Review GET IT
Times cited: 8
Assays for expression of genes regulated by retinoic acid in murine teratocarcinoma cell lines. Methods in enzymology. 1990 Academic Article GET IT
Times cited: 8
Cyclic AMP analogs and retinoic acid influence the expression of retinoic acid receptor alpha, beta, and gamma mRNAs in F9 teratocarcinoma cells. Molecular and cellular biology. 1990 Academic Article GET IT
Times cited: 154
Region-specific expression in early chick and mouse embryos of Ghox-lab and Hox 1.6, vertebrate homeobox-containing genes related to Drosophila labial. Development (Cambridge, England). 1990 Academic Article GET IT
Times cited: 75
The regulation of the expression of genes encoding basement membrane proteins during the retinoic acid-associated differentiation of murine teratocarcinoma cells. Annals of the New York Academy of Sciences. 1990 Academic Article GET IT
Times cited: 24
Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse. Nature. 1989 Academic Article GET IT
Times cited: 375
A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene. Proceedings of the National Academy of Sciences of the United States of America. 1989 Academic Article GET IT
Times cited: 250
Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells. Molecular and cellular biology. 1989 Academic Article GET IT
Times cited: 162
Defective post-translational modification of collagen IV in a mutant F9 teratocarcinoma cell line is associated with delayed differentiation and growth arrest in response to retinoic acid. The Journal of biological chemistry. 1989 Academic Article GET IT
Times cited: 11
Expression of fibroblast growth factor by F9 teratocarcinoma cells as a function of differentiation. The Journal of cell biology. 1989 Academic Article GET IT
Times cited: 15
Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells. Cancer research. 1989 Academic Article GET IT
Times cited: 111
Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox. Molecular and cellular biology. 1988 Academic Article GET IT
Times cited: 156
Protein synthesis inhibitors prevent the induction of laminin B1, collagen IV (alpha 1), and other differentiation-specific mRNAs by retinoic acid in F9 teratocarcinoma cells. Journal of cellular physiology. 1988 Academic Article GET IT
Times cited: 21
An early effect of retinoic acid: cloning of an mRNA (Era-1) exhibiting rapid and protein synthesis-independent induction during teratocarcinoma stem cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 1988 Academic Article GET IT
Times cited: 140
The effect of dibutyryl cyclic AMP and butyrate on F9 teratocarcinoma cellular retinoic acid-binding protein activity. The Journal of biological chemistry. 1987 Academic Article GET IT
Times cited: 23
Deoxyribonucleotide metabolism and cyclic AMP resistance in hydroxyurea-resistant S49 T-lymphoma cells. Journal of cellular physiology. 1987 Academic Article GET IT
Times cited: 9
Discrimination among multiple AATAAA sequences correlates with interspecies conservation of select 3' untranslated nucleotides. Nucleic acids research. 1986 Academic Article GET IT
Times cited: 19
Selection and characterization of mutant S49 T-lymphoma cell lines resistant to phosphonoformic acid: evidence for inhibition of ribonucleotide reductase. Journal of cellular physiology. 1986 Academic Article GET IT
Times cited: 5
Characterization of hydroxyurea (HYU) resistant S49 T lymphoma cells. Advances in experimental medicine and biology. 1986 Academic Article GET IT
Localization of the human procollagen alpha 1(IV) gene to chromosome 13q34 by in situ hybridization. American journal of human genetics. 1986 Academic Article GET IT
Times cited: 35
The effect of phosphonoformic acid on wild type and mutant S49 cell lines. Advances in experimental medicine and biology. 1986 Academic Article GET IT
The regulation of collagen type IV(alpha 1) and other genes during the retinoic acid induced differentiation of wild type and mutant mouse teratocarcinoma stem cells. Progress in clinical and biological research. 1986 Academic Article GET IT
Times cited: 6
An increase in prolyl-4-hydroxylase activity occurs during the retinoic acid-induced differentiation of mouse teratocarcinoma stem cell lines F9 and P19. The Journal of biological chemistry. 1985 Academic Article GET IT
Times cited: 16
Improved synthesis of 2'-deoxyformycin A and studies of its in vitro activity against mouse lymphoma of T-cell origin. Journal of medicinal chemistry. 1985 Academic Article GET IT
Times cited: 20
Restricted homology between human alpha 1 type IV and other procollagen chains. Proceedings of the National Academy of Sciences of the United States of America. 1985 Academic Article GET IT
Times cited: 62
Ribonucleotide reductase activity and deoxyribonucleoside triphosphate metabolism during the cell cycle of S49 wild-type and mutant mouse T-lymphoma cells. The Journal of biological chemistry. 1985 Academic Article GET IT
Times cited: 23
Molecular cloning of gene sequences transcriptionally regulated by retinoic acid and dibutyryl cyclic AMP in cultured mouse teratocarcinoma cells. Developmental biology. 1985 Academic Article GET IT
Times cited: 150
Butyrate inhibits the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells. Developmental biology. 1984 Academic Article GET IT
Times cited: 21
Isolation of cDNA clones for genes exhibiting reduced expression after differentiation of murine teratocarcinoma stem cells. Molecular and cellular biology. 1984 Academic Article GET IT
Times cited: 25
Selection and characterization of F9 teratocarcinoma stem cell mutants with altered responses to retinoic acid. The Journal of biological chemistry. 1984 Academic Article GET IT
Times cited: 51
Mutator phenotype in a mutant of S49 mouse T-lymphoma cells with abnormal sensitivity to thymidine. The Journal of biological chemistry. 1984 Academic Article GET IT
Times cited: 10
Isolation of cDNA clones specific for collagen IV and laminin from mouse teratocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 1983 Academic Article GET IT
Times cited: 114
Demonstration of normal and mutant protein M1 subunits of deoxyGTP-resistant ribonucleotide reductase from mutant mouse lymphoma cells. The Journal of biological chemistry. 1981 Academic Article GET IT
Times cited: 14
DeoxyATP-resistant ribonucleotide reductase of mutant mouse lymphoma cells. Evidence for heterozygosity for the protein M1 subunits. The Journal of biological chemistry. 1981 Academic Article GET IT
Times cited: 14
Evidence for genetically independent allosteric regulatory domains of the protein M1 subunit of mouse ribonucleotide reductase. The Journal of biological chemistry. 1981 Academic Article GET IT
Times cited: 29
Alterations in deoxyribonucleotide metabolism in cultured cells with ribonucleotide reductase activities refractory to feedback inhibition by 2'-deoxyadenosine triphosphate. The Journal of biological chemistry. 1980 Academic Article GET IT
Times cited: 40
Characterization of the subunit composition of HGPRTase from human erythrocytes and cultured fibroblasts. Biochemical genetics. 1980 Academic Article GET IT
Times cited: 12
Abnormal regulation of purine metabolism in a cultured mouse T-cell lymphoma mutant partially deficient in adenylosuccinate synthetase. Advances in experimental medicine and biology. 1980 Academic Article GET IT
Times cited: 1
Purification of a mutant ribonucleotide reductase from cultured mouse T-lymphoma cells. Advances in enzyme regulation. 1980 Academic Article GET IT
Times cited: 5
Characterization of the subunits of purine nucleoside phosphorylase from cultured normal human fibroblasts. Biochemical genetics. 1979 Academic Article GET IT
Times cited: 2
Abnormal regulation of de novo purine synthesis and purine salvage in a cultured mouse T-cell lymphoma mutant partially deficient in adenylosuccinate synthetase. Journal of cellular physiology. 1979 Academic Article GET IT
Times cited: 12
Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: genetic model for immunodeficiency disease. Proceedings of the National Academy of Sciences of the United States of America. 1979 Academic Article GET IT
Times cited: 101
Degradation of Escherichia coli DNA: evidence for limitation in vivo by protein X, the recA gene product. Molecular & general genetics : MGG. 1979 Academic Article GET IT
Times cited: 32
Characterization of mutant subunits of human purine nucleoside phosphorylase. The Journal of biological chemistry. 1978 Academic Article GET IT
Times cited: 10
Deoxyguanosine toxicity in a mouse T lymphoma: relationship to purine nucleoside phosphorylase-associated immune dysfunction. Cell. 1978 Academic Article GET IT
Times cited: 85
Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease. Cell. 1978 Academic Article GET IT
Times cited: 150
Deoxyguanosine triphosphate as a possible toxic metabolite in the immunodeficiency associated with purine nucleoside phosphorylase deficiency. The Journal of clinical investigation. 1978 Academic Article GET IT
Times cited: 129
Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells. Somatic cell genetics. 1978 Academic Article GET IT
Times cited: 51
Nucleotide metabolism in cultured T cells and in cells of patients deficient in adenosine deaminase and purine nucleoside phosphorylase. Ciba Foundation symposium. 1978 Academic Article GET IT
Times cited: 3
Identification of the recA (tif) gene product of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 1977 Academic Article GET IT
Times cited: 114
Purification and characterization of hypoxanthine-guanine phosphoribosyl transferase from cultured HTC cells. Advances in experimental medicine and biology. 1977 Academic Article GET IT
The induction of protein X in DNA repair and cell division mutants of Escherichia coli. Journal of molecular biology. 1976 Academic Article GET IT
Times cited: 43
Evidence of the involvement of an outer membrane protein in DNA initiation. The Journal of biological chemistry. 1976 Academic Article GET IT
Times cited: 23
DNA synthesis inhibition and the induction of protein X in Escherichia coli. Journal of molecular biology. 1976 Academic Article GET IT
Times cited: 151
Cell cycle-specific incorporation of lipoprotein into the outer membrane of Escherichia coli. Journal of bacteriology. 1976 Academic Article GET IT
Times cited: 9
Model for regulation of Escherichia coli DNA repair functions. Proceedings of the National Academy of Sciences of the United States of America. 1975 Academic Article GET IT
Times cited: 139
Deoxyribonucleic acid synthesis during the division cycle of Escherichia coli: a comparison of strains B-r, K-12, 15, and 15T- under conditions of slow growth. Journal of bacteriology. 1974 Academic Article GET IT
Times cited: 23

more ...

less ...

Research

Sort by

Co-investigator Network

Funding awarded

Gene Nutrient Interactions in Kidney Function awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator 2022 - 2026
ATF4 in ccRCC: A New Therapeutic Approach awarded by United States Department of Defense Principal Investigator 2022 - 2025
Cancer Pharmacology awarded by National Cancer Institute Principal Investigator 2020 - 2025
Characterization of Premalignant Fields in a Murine Model of Head and Neck and Esophageal Cancers awarded by National Cancer Institute Principal Investigator 2016 - 2023

Weill Cornell Medicine (WCM) SPORE in Prostate Cancer awarded by National Cancer Institute Key Personnel 2017 - 2023

more ...

less ...

Background

education and training

Ph.D., Princeton University 1975
B.A., Smith College 1970

Contact

full name

Lorraine Gudas

primary email

ljgudas@med.cornell.edu

VIVO Weill Cornell Medical College

Lorraine Gudas Chair of Pharmacology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email