D'Aurelio, Marilena

Publications

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selected publications

A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy. EMBO molecular medicine. 2023 Academic Article GET IT
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations. Cell metabolism. 2018 Academic Article GET IT
Times cited: 105
Distinct intracellular sAC-cAMP domains regulate ER Ca²⁺ signaling and OXPHOS function. Journal of cell science. 2017 Academic Article GET IT
Times cited: 21
Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection. Molecules (Basel, Switzerland). 2017 Academic Article GET IT
Times cited: 40
The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility. Nature communications. 2017 Academic Article GET IT
Times cited: 154
Bioenergetic markers in skin fibroblasts of sporadic amyotrophic lateral sclerosis and progressive lateral sclerosis patients. Annals of neurology. 2014 Academic Article GET IT
Times cited: 27
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Human molecular genetics. 2013 Academic Article GET IT
Times cited: 88
Barth syndrome: cellular compensation of mitochondrial dysfunction and apoptosis inhibition due to changes in cardiolipin remodeling linked to tafazzin (TAZ) gene mutation. Biochimica et biophysica acta. 2013 Academic Article GET IT
Times cited: 127
Prohibitin reduces mitochondrial free radical production and protects brain cells from different injury modalities. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Academic Article GET IT
Times cited: 73
Mitochondrial DNA background modifies the bioenergetics of NARP/MILS ATP6 mutant cells. Human molecular genetics. 2009 Academic Article GET IT
Times cited: 74
An assembled complex IV maintains the stability and activity of complex I in mammalian mitochondria. The Journal of biological chemistry. 2007 Academic Article GET IT
Times cited: 96
Respiratory chain supercomplexes set the threshold for respiration defects in human mtDNA mutant cybrids. Human molecular genetics. 2006 Academic Article GET IT
Times cited: 105
Mitochondrial activities of a cell line derived from thyroid Hürthle cell tumors. Thyroid : official journal of the American Thyroid Association. 2006 Academic Article GET IT
Times cited: 21
Heterologous mitochondrial DNA recombination in human cells. Human molecular genetics. 2004 Academic Article GET IT
Times cited: 85
Bioenergetics of mitochondrial diseases associated with mtDNA mutations. Biochimica et biophysica acta. 2004 Review GET IT
Times cited: 90
Plasma membrane oxidoreductase activity in cultured cells in relation to mitochondrial function and oxidative stress. BioFactors (Oxford, England). 2004 Academic Article GET IT
Times cited: 2
BCL-2 improves oxidative phosphorylation and modulates adenine nucleotide translocation in mitochondria of cells harboring mutant mtDNA. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 40
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 477
Role of mitochondria in oxidative stress and aging. Annals of the New York Academy of Sciences. 2002 Review GET IT
Times cited: 338
Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress. Free radical research. 2002 Academic Article GET IT
Times cited: 19
Enhanced activity of the plasma membrane oxidoreductase in circulating lymphocytes from insulin-dependent diabetes mellitus patients. Biochemical and biophysical research communications. 2002 Academic Article GET IT
Times cited: 22
In vivo regulation of oxidative phosphorylation in cells harboring a stop-codon mutation in mitochondrial DNA-encoded cytochrome c oxidase subunit I. The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 65
Decreased Pasteur effect in platelets of aged individuals. Mechanisms of ageing and development. 2001 Academic Article GET IT
Times cited: 37
Lymphocyte dysmetabolism: an immunocytochemical comparative approach in IDDM and control subjects. European journal of histochemistry : EJH. 2001 Academic Article GET IT
Times cited: 1
Mitochondrial bioenergetics in aging. Biochimica et biophysica acta. 2000 Review GET IT
Times cited: 161
Protective effect of exogenous coenzyme Q in rats subjected to partial hepatic ischemia and reperfusion. BioFactors (Oxford, England). 1999 Academic Article GET IT
Times cited: 20
Tyrosine phosphorylation in type-1 diabetes by immunogold detection: an in vitro human aortic endothelial cell (HAEC) study in the presence of diabetic low density lipoproteins (LDL). European journal of histochemistry : EJH. 1999 Academic Article GET IT
Times cited: 2
Oxidative stress, antioxidant defences and aging. BioFactors (Oxford, England). 1998 Review GET IT
Times cited: 66
Coenzyme Q deficiency in mitochondria: kinetic saturation versus physical saturation. Molecular aspects of medicine. 1997 Review GET IT
Times cited: 30

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Research

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Funding awarded

Metabolic remodeling of skeletal muscle in mitochondrial myopathies awarded by National Inst of Arthritis & Musculoskeletal & Skin Diseases Principal Investigator 2020 - 2025
Modulation Of Intermediate Metabolism, A New Therapeutic Approach For Mitochondrial Encephalomyopathies awarded by National Institute of Neurological Disorders & Stroke Principal Investigator 2021 - 2023

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Background

education and training

Ph.D., University of Bologna (Italy) 2001
B.S., M.S., University of Bologna (Italy) 1996

Contact

full name

Marilena D'Aurelio

primary email

mad2003@med.cornell.edu

VIVO Weill Cornell Medical College

Marilena D'Aurelio Associate Professor of Research in Neuroscience

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email