Weksler, Babette B

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selected publications

Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis. Scientific reports. 2018 Academic Article GET IT
Times cited: 28
Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro. Antimicrobial agents and chemotherapy. 2017 Academic Article GET IT
Times cited: 19
Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis. Scientific reports. 2017 Academic Article GET IT
Times cited: 37
New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator. Cardiovascular research. 2017 Academic Article GET IT
Times cited: 13
Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca²⁺ influx through cyclic nucleotide-gated channels. The Journal of physiology. 2017 Academic Article GET IT
Times cited: 18
Effect of cigarette smoke on monocyte procoagulant activity: Focus on platelet-derived brain-derived neurotrophic factor (BDNF). Platelets. 2016 Academic Article GET IT
Times cited: 13
Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells. Cellular and molecular life sciences : CMLS. 2016 Academic Article GET IT
Times cited: 25
Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier. International journal of molecular sciences. 2016 Academic Article GET IT
Times cited: 15
Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development. Pain. 2016 Academic Article GET IT
Times cited: 45
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Review GET IT
Times cited: 489
Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?. Scientific reports. 2016 Academic Article GET IT
Times cited: 59
Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System. Journal of immunology (Baltimore, Md. : 1950). 2016 Academic Article GET IT
Times cited: 61
Solid lipid nanoparticles as a vehicle for brain-targeted drug delivery: two new strategies of functionalization with apolipoprotein E. Nanotechnology. 2015 Academic Article GET IT
Times cited: 79
Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal. Free radical biology & medicine. 2015 Academic Article GET IT
Times cited: 15
Protective effect of the multitarget compound DPH-4 on human SSAO/VAP-1-expressing hCMEC/D3 cells under oxygen-glucose deprivation conditions: an in vitro experimental model of cerebral ischaemia. British journal of pharmacology. 2015 Academic Article GET IT
Times cited: 12
Characterizing the pathotype of neonatal meningitis causing Escherichia coli (NMEC). BMC microbiology. 2015 Academic Article GET IT
Times cited: 50
Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis. Virulence. 2015 Academic Article GET IT
Times cited: 22
Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice. Thrombosis and haemostasis. 2015 Academic Article GET IT
Times cited: 12
Prostanoids and NSAIDs in cardiovascular biology and disease. Current atherosclerosis reports. 2015 Review GET IT
Times cited: 13
Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4. International immunology. 2015 Academic Article GET IT
Times cited: 66
Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier. The Journal of general virology. 2015 Academic Article GET IT
Times cited: 13
Development of a solvent-free analytical method for paracetamol quantitative determination in Blood Brain Barrier in vitro model. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Academic Article GET IT
Times cited: 12
Microparticles in multiple sclerosis and clinically isolated syndrome: effect on endothelial barrier function. BMC neuroscience. 2014 Academic Article GET IT
Times cited: 69
Permeability of PEGylated immunoarsonoliposomes through in vitro blood brain barrier-medulloblastoma co-culture models for brain tumor therapy. Pharmaceutical research. 2014 Academic Article GET IT
Times cited: 17
The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family. The AAPS journal. 2014 Academic Article GET IT
Times cited: 65
Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?. BMC neuroscience. 2014 Academic Article GET IT
Times cited: 89
Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses. PloS one. 2014 Academic Article GET IT
Times cited: 36
CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro. American journal of physiology. Endocrinology and metabolism. 2014 Academic Article GET IT
Times cited: 40
Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C. PloS one. 2014 Academic Article GET IT
Times cited: 31
Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling. Neuropharmacology. 2014 Academic Article GET IT
Times cited: 93
Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier. Cancer research. 2013 Academic Article GET IT
Times cited: 40
Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles. The Analyst. 2013 Academic Article GET IT
Times cited: 34
A recombinant inhibitory isoform of vascular endothelial growth factor164/165 aggravates ischemic brain damage in a mouse model of focal cerebral ischemia. The American journal of pathology. 2013 Academic Article GET IT
Times cited: 13
Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia. Cerebrovascular diseases (Basel, Switzerland). 2013 Academic Article GET IT
Times cited: 23
Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis. Biochemical pharmacology. 2013 Academic Article GET IT
Times cited: 26
A multi-system approach assessing the interaction of anticonvulsants with P-gp. PloS one. 2013 Academic Article GET IT
Times cited: 24
The hCMEC/D3 cell line as a model of the human blood brain barrier. Fluids and barriers of the CNS. 2013 Academic Article GET IT
Times cited: 496
Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction. Gene. 2013 Academic Article GET IT
Times cited: 9
The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients. Vascular cell. 2013 Academic Article GET IT
Times cited: 34
BBB on chip: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function. Biomedical microdevices. 2013 Academic Article GET IT
Times cited: 396
Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS. Scientific reports. 2013 Academic Article GET IT
Times cited: 48
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 141
The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases in vitro drug delivery across blood-brain barrier cells. British journal of pharmacology. 2012 Academic Article GET IT
Times cited: 70
Alzheimer's disease and Down's syndrome: treating two paths to dementia. Autoimmunity reviews. 2012 Review GET IT
Times cited: 21
Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier. Journal of neuroscience methods. 2012 Academic Article GET IT
Times cited: 81
T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 11
Cyclooxygenase-2-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor in a sirtuin-1-dependent-manner. Circulation. 2012 Academic Article GET IT
Times cited: 44
Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells. Particle and fibre toxicology. 2012 Academic Article GET IT
Times cited: 118
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 Academic Article GET IT
Times cited: 138
CCL2 disrupts the adherens junction: implications for neuroinflammation. Laboratory investigation; a journal of technical methods and pathology. 2012 Academic Article GET IT
Times cited: 71
The epidemic of distraction. Gerontology. 2012 Academic Article GET IT
Times cited: 12
Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura. British journal of haematology. 2012 Letter GET IT
Times cited: 79
The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine. Molecular pharmaceutics. 2012 Academic Article GET IT
Times cited: 17
Expression and localization of claudins-3 and -12 in transformed human brain endothelium. Fluids and barriers of the CNS. 2012 Academic Article GET IT
Times cited: 26
Lamotrigine is a substrate for OCT1 in brain endothelial cells. Biochemical pharmacology. 2011 Academic Article GET IT
Times cited: 70
The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein. Brain research. 2011 Academic Article GET IT
Times cited: 19
Hepatitis C virus infects the endothelial cells of the blood-brain barrier. Gastroenterology. 2011 Academic Article GET IT
Times cited: 177
Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro. Journal of neuroinflammation. 2011 Academic Article GET IT
Times cited: 29
IgG from patients with pulmonary arterial hypertension and/or systemic sclerosis binds to vascular smooth muscle cells and induces cell contraction. Annals of the rheumatic diseases. 2011 Academic Article GET IT
Times cited: 36
Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3. Purinergic signalling. 2011 Academic Article GET IT
Times cited: 437
Tobacco smoke regulates the expression and activity of microsomal prostaglandin E synthase-1: role of prostacyclin and NADPH-oxidase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2011 Academic Article GET IT
Times cited: 15
Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach. Arthritis research & therapy. 2011 Academic Article GET IT
Times cited: 41
Chemokines stimulate bidirectional migration of human mesenchymal stem cells across bone marrow endothelial cells. Stem cells and development. 2011 Academic Article GET IT
Times cited: 61
Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models. Journal of neuroscience methods. 2011 Academic Article GET IT
Times cited: 249
Human brain endothelial cells are responsive to adenosine receptor activation. Purinergic signalling. 2011 Academic Article GET IT
Times cited: 94
Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction. Cardiovascular research. 2011 Academic Article GET IT
Times cited: 93
Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. European journal of cell biology. 2010 Academic Article GET IT
Times cited: 72
Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2010 Academic Article GET IT
Times cited: 107
Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro. Molecular therapy : the journal of the American Society of Gene Therapy. 2010 Academic Article GET IT
Times cited: 152
A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody. Journal of cellular physiology. 2010 Academic Article GET IT
Times cited: 6
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. PloS one. 2010 Academic Article GET IT
Times cited: 37
ABC and SLC transporter expression and proton oligopeptide transporter (POT) mediated permeation across the human blood--brain barrier cell line, hCMEC/D3 [corrected]. Molecular pharmaceutics. 2010 Academic Article GET IT
Times cited: 79
Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions. PLoS pathogens. 2010 Academic Article GET IT
Times cited: 83
Identification of peptide ligands for targeting to the blood-brain barrier. Pharmaceutical research. 2010 Academic Article GET IT
Times cited: 59
Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 Academic Article GET IT
Times cited: 64
Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by Cryptococcus neoformans. Eukaryotic cell. 2009 Academic Article GET IT
Times cited: 92
Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies. Brain research. 2009 Academic Article GET IT
Times cited: 64
Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line. Journal of leukocyte biology. 2009 Academic Article GET IT
Times cited: 50
Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2009 Academic Article GET IT
Times cited: 162
Role of KCNMA1 gene in breast cancer invasion and metastasis to brain. BMC cancer. 2009 Academic Article GET IT
Times cited: 98
Tobacco smoke: a critical etiological factor for vascular impairment at the blood-brain barrier. Brain research. 2009 Academic Article GET IT
Times cited: 63
Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. Science (New York, N.Y.). 2009 Academic Article GET IT
Times cited: 170
Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment. Journal of neuroimmunology. 2009 Academic Article GET IT
Times cited: 16
Effects of transforming growth factor-beta1 on human vocal fold fibroblasts. The Annals of otology, rhinology, and laryngology. 2009 Academic Article GET IT
Times cited: 52
Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line. Journal of neuroscience research. 2009 Academic Article GET IT
Times cited: 112
Signaling mechanism of extracellular RNA in endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 Academic Article GET IT
Times cited: 50
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiology of disease. 2008 Academic Article GET IT
Times cited: 174
Review: recent advances in argatroban-warfarin transition in patients with heparin-induced thrombocytopenia. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 2008 Review GET IT
Times cited: 4
The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies. Journal of neurochemistry. 2008 Academic Article GET IT
Times cited: 249
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells. Biochemical pharmacology. 2008 Academic Article GET IT
Times cited: 151
Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha. Journal of cellular biochemistry. 2008 Academic Article GET IT
Times cited: 29
Caveolin-1 regulates human immunodeficiency virus-1 Tat-induced alterations of tight junction protein expression via modulation of the Ras signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Academic Article GET IT
Times cited: 96
Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells. Journal of neurochemistry. 2008 Academic Article GET IT
Times cited: 135
Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. The Journal of biological chemistry. 2008 Academic Article GET IT
Times cited: 104
Thrombocytopenia associated with chronic liver disease. Journal of hepatology. 2008 Review GET IT
Times cited: 407
Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. The Journal of physiology. 2008 Academic Article GET IT
Times cited: 249
Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium. Arteriosclerosis, thrombosis, and vascular biology. 2008 Academic Article GET IT
Times cited: 48
Regulated complement deposition on the surface of human endothelial cells: effect of tobacco smoke and shear stress. Thrombosis research. 2007 Academic Article GET IT
Times cited: 33
Review article: the pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease. Alimentary pharmacology & therapeutics. 2007 Review GET IT
Times cited: 84
Inhibition of Jun NH2-terminal kinases suppresses the growth of experimental head and neck squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Academic Article GET IT
Times cited: 38
The role of platelet/endothelial cell adhesion molecule 1 (CD31) and CD38 antigens in marrow microenvironmental retention of acute myelogenous leukemia cells. Cancer research. 2007 Academic Article GET IT
Times cited: 29
Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization. Journal of immunology (Baltimore, Md. : 1950). 2007 Academic Article GET IT
Times cited: 83
Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2007 Academic Article GET IT
Times cited: 218
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2007 Academic Article GET IT
Times cited: 282
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita. Blood. 2007 Academic Article GET IT
Times cited: 270
Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells. Cancer. 2007 Academic Article GET IT
Times cited: 99
Examination of platelet function in whole blood under dynamic flow conditions with the cone and plate(let) analyzer: effect of erythrocytosis and thrombocytosis. American journal of clinical pathology. 2007 Academic Article GET IT
Times cited: 21
Tobacco smoke cooperates with interleukin-1beta to alter beta-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2007 Academic Article GET IT
Times cited: 74
Potentially reduced exposure cigarettes accelerate atherosclerosis: evidence for the role of nicotine. Cardiovascular toxicology. 2007 Academic Article GET IT
Times cited: 38
Classical pathway complement activation on human endothelial cells. Molecular immunology. 2006 Academic Article GET IT
Times cited: 25
The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKC epsilon inhibition. Proceedings of the National Academy of Sciences of the United States of America. 2006 Academic Article GET IT
Times cited: 184
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure. Blood cells, molecules & diseases. 2006 Letter GET IT
Times cited: 25
Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2005 Academic Article GET IT
Times cited: 1051
Linking thrombophilia and idiopathic intracranial hypertension. The Journal of laboratory and clinical medicine. 2005 Editorial Article GET IT
Times cited: 5
Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands. Cancer research. 2005 Academic Article GET IT
Times cited: 118
Rituximab for autoimmune haemophilia: a proposed treatment algorithm. Haemophilia : the official journal of the World Federation of Hemophilia. 2005 Review GET IT
Times cited: 89
Ex vivo evaluation of erythrocytosis-enhanced platelet thrombus formation using the cone and plate(let) analyzer: effect of platelet antagonists. British journal of haematology. 2004 Academic Article GET IT
Times cited: 20
Stimulation of endothelial IL-8 (eIL-8) production and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells. Chemico-biological interactions. 2004 Academic Article GET IT
Times cited: 13
Correlation of thrombophilia and hypofibrinolysis with pulmonary embolism following total hip arthroplasty: an analysis of genetic factors. The Journal of bone and joint surgery. American volume. 2002 Academic Article GET IT
Times cited: 62
Rituximab in the treatment of acquired factor VIII inhibitors. Blood. 2002 Academic Article GET IT
Times cited: 186
Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer. The Lancet. Oncology. 2001 Review GET IT
Times cited: 496
[Arachidonic acid and prostaglandins, inflammation and oncology]. Presse medicale (Paris, France : 1983). 2001 Academic Article GET IT
Times cited: 14
[Cyclooxygenase inhibitors]. Presse medicale (Paris, France : 1983). 2001 Academic Article GET IT
Times cited: 2
[Cyclooxygenases]. Presse medicale (Paris, France : 1983). 2001 Academic Article GET IT
Times cited: 2
Benzo[a]pyrene induces the transcription of cyclooxygenase-2 in vascular smooth muscle cells. Evidence for the involvement of extracellular signal-regulated kinase and NF-kappaB. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 103
Up-regulation of endothelial cell binding proteins/receptors for complement component C1q by inflammatory cytokines. The Journal of laboratory and clinical medicine. 1999 Academic Article GET IT
Times cited: 38
Enhanced endothelial cell apoptosis in splenic tissues of patients with thrombotic thrombocytopenic purpura. Blood. 1999 Academic Article GET IT
Times cited: 66
Profibrinolytic properties characterize a stably transformed human endothelial cell line. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 1998 Academic Article GET IT
Times cited: 4
Cyclooxygenase-2 gene expression is upregulated in transformed mammary epithelial cells. Annals of the New York Academy of Sciences. 1997 Academic Article GET IT
Times cited: 18
Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells. The Journal of clinical investigation. 1997 Academic Article GET IT
Times cited: 159
Inhibition of cyclooxygenase: a novel approach to cancer prevention. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1997 Review GET IT
Times cited: 224
Thrombotic thrombocytopenic purpura and sporadic hemolytic-uremic syndrome plasmas induce apoptosis in restricted lineages of human microvascular endothelial cells. Blood. 1997 Academic Article GET IT
Times cited: 172
Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer research. 1996 Academic Article GET IT
Times cited: 424
Serum levels of GM-CSF are elevated in patients with thrombocytopenia. British journal of haematology. 1996 Academic Article GET IT
Times cited: 19
Alpha 2-macroglobulin/transforming growth factor-beta 1 interactions. Modulation by heparin-like molecules and effects on vascular smooth muscle cells. Annals of the New York Academy of Sciences. 1994 Academic Article GET IT
Times cited: 7
Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion. Blood. 1994 Academic Article GET IT
Times cited: 241
Regulation of cyclooxygenase-2 expression in aortic smooth muscle cells. Arteriosclerosis and thrombosis : a journal of vascular biology. 1994 Academic Article GET IT
Times cited: 152
Differential induction of glutathione S-transferase in rat aorta versus liver. Biochemical pharmacology. 1994 Academic Article GET IT
Times cited: 10
The age-dependent proliferation of rat aortic smooth muscle cells is independent of differential splicing of PDGF A-chain mRNA. Mechanisms of ageing and development. 1993 Academic Article GET IT
Times cited: 8
Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia. Biochemical and biophysical research communications. 1992 Academic Article GET IT
Times cited: 45
Heparanase activity in cultured endothelial cells. Journal of cellular physiology. 1991 Academic Article GET IT
Times cited: 34
Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex. The Journal of cell biology. 1989 Academic Article GET IT
Times cited: 191
Aging and arteriosclerosis. The increased proliferation of arterial smooth muscle cells isolated from old rats is associated with increased platelet-derived growth factor-like activity. The Journal of experimental medicine. 1988 Academic Article GET IT
Times cited: 89
Herpes simplex virus infection in human arterial cells. Implications in arteriosclerosis. The Journal of clinical investigation. 1987 Academic Article GET IT
Times cited: 90
Cholesterol metabolism is altered by hydrolytic metabolites of prostacyclin in arterial smooth muscle cells. Journal of lipid research. 1986 Academic Article GET IT
Times cited: 7
IgE-mediated hypersensitivity in human heart tissue: histamine release and functional changes. The Journal of allergy and clinical immunology. 1986 Academic Article GET IT
Times cited: 24
Modulation of arterial cholesteryl ester metabolism by prostacyclin and prostaglandin E2. Advances in prostaglandin, thromboxane, and leukotriene research. 1985 Academic Article GET IT
Times cited: 1
Effects of nutrition of disease and life span. II. Vascular disease, serum cholesterol, serum thromboxane, and heart-produced prostacyclin in MRL mice. The American journal of pathology. 1984 Academic Article GET IT
Times cited: 7
Metabolic activity of cholesteryl esters in aortic smooth muscle cells is altered by prostaglandins I2 and E2. Journal of lipid research. 1983 Academic Article GET IT
Times cited: 66
Purification of human platelet calcium-activated protease. Effect on platelet and endothelial function. The Journal of biological chemistry. 1983 Academic Article GET IT
Times cited: 60
Cultured endothelial cells increase their capacity to synthesize prostacyclin following the formation of a contact inhibited cell monolayer. Journal of cellular physiology. 1983 Academic Article GET IT
Times cited: 30
Interactions between prostacyclin metabolism and cholesteryl ester metabolism in the vascular wall. Advances in prostaglandin, thromboxane, and leukotriene research. 1983 Academic Article GET IT
Times cited: 11
Prostacyclin modulates cholesteryl ester hydrolytic activity by its effect on cyclic adenosine monophosphate in rabbit aortic smooth muscle cells. The Journal of clinical investigation. 1982 Academic Article GET IT
Times cited: 105
Diet-induced hypercholesterolemia inhibits the recovery of prostacyclin production by injured rabbit aorta. The American journal of pathology. 1982 Academic Article GET IT
Times cited: 20
Arachidonic acid metabolism in endothelial cells and platelets. Annals of the New York Academy of Sciences. 1982 Academic Article GET IT
Times cited: 15
Effects of acetyl glyceryl ether phosphorylcholine on human platelet function in vitro. Blood. 1981 Academic Article GET IT
Times cited: 79
Platelets and atherosclerosis. The American journal of medicine. 1981 Academic Article GET IT
Times cited: 46
Interactions between stimulated platelets and endothelial cells in vitro. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 1981 Academic Article GET IT
Times cited: 15
Recovery of prostacyclin production by de-endothelialized rabbit aorta. Critical role of neointimal smooth muscle cells. The Journal of clinical investigation. 1981 Academic Article GET IT
Times cited: 128
Human complement in the arachidonic acid transformation pathway in platelets. The Journal of experimental medicine. 1981 Academic Article GET IT
Times cited: 35
Platelet FcIgG receptor: increased expression in female platelets. Thrombosis research. 1981 Academic Article GET IT
Times cited: 5
Arachidonic acid metabolism in platelets and endothelial cells. Progress in lipid research. 1981 Academic Article GET IT
Times cited: 2
Synthesis of prostacyclin from platelet-derived endoperoxides by cultured human endothelial cells. The Journal of clinical investigation. 1980 Academic Article GET IT
Times cited: 232
In vivo measurement of platelet activity in postoperative patients. Surgical forum. 1979 Academic Article GET IT
Enzymatic conversion of prostaglandin endoperoxide H2 and arachidonic acid to prostacyclin by cultured human endothelial cells. The Journal of biological chemistry. 1978 Academic Article GET IT
Times cited: 133
Wheat germ agglutinin affinity chromatography of human platelet membrane glycoproteins. Thrombosis research. 1978 Academic Article GET IT
Times cited: 26
Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1977 Academic Article GET IT
Times cited: 486
Immunoinhibition of ristocetin-induced platelet aggregation. The Journal of clinical investigation. 1977 Academic Article GET IT
Times cited: 40
The platelet as an inflammatory cell. Annals of the New York Academy of Sciences. 1972 Academic Article GET IT
Times cited: 48
Characterization of human platelet vascular permeability-enhancing activity. The Journal of clinical investigation. 1972 Academic Article GET IT
Times cited: 84
Rabbit platelet bactericidal protein. The Journal of experimental medicine. 1971 Academic Article GET IT
Times cited: 59
Increased vascular permeability produced by human platelet granule cationic extract. The Journal of clinical investigation. 1970 Academic Article GET IT
Times cited: 56

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Background

education and training

M.D., Columbia University College of Physicians and Surgeons 1963
B.A., Swarthmore College 1958

Contact

full name

Babette B Weksler

primary email

babette@med.cornell.edu

VIVO Weill Cornell Medical College

Babette B Weksler Professor Emerita of Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email