Rhee, Kyu Y.

Publications

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selected publications

Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice. G3 (Bethesda, Md.). 2023 Academic Article GET IT
Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis. mBio. 2023 Academic Article GET IT
Sexual differentiation in human malaria parasites is regulated by competition between phospholipid metabolism and histone methylation. Nature microbiology. 2023 Academic Article GET IT
Times cited: 1982
The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching. Proceedings of the National Academy of Sciences of the United States of America. 2023 Academic Article GET IT
Times cited: 124
Colorectal cancer detection and treatment with engineered probiotics. bioRxiv : the preprint server for biology. 2023 Article GET IT
Listeria monocytogenes GlmR Is an Accessory Uridyltransferase Essential for Cytosolic Survival and Virulence. mBio. 2023 Academic Article GET IT
Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice. bioRxiv : the preprint server for biology. 2023 Article GET IT
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis. eLife. 2023 Academic Article GET IT
Times cited: 55
Mutations in rpoB That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility. mBio. 2023 Academic Article GET IT
Times cited: 3
Evolution and regulation of microbial secondary metabolism. eLife. 2022 Academic Article GET IT
Times cited: 2
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nature communications. 2022 Academic Article GET IT
Times cited: 182
CinA mediates multidrug tolerance in Mycobacterium tuberculosis. Nature communications. 2022 Academic Article GET IT
Times cited: 7
Activity-based annotation: the emergence of systems biochemistry. Trends in biochemical sciences. 2022 Review GET IT
Times cited: 4
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
Times cited: 13
Deciphering functional redundancy and energetics of malate oxidation in mycobacteria. The Journal of biological chemistry. 2022 Academic Article GET IT
Times cited: 5
An amiloride derivative is active against the F₁F_o-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis. Communications biology. 2022 Academic Article GET IT
Times cited: 13
A d-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis. ACS infectious diseases. 2022 Academic Article GET IT
Times cited: 1
Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection. Nature communications. 2021 Academic Article GET IT
Times cited: 9
Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis. Microbiology spectrum. 2021 Academic Article GET IT
Multiform antimicrobial resistance from a metabolic mutation. Science advances. 2021 Academic Article GET IT
Times cited: 14
Dietary fructose improves intestinal cell survival and nutrient absorption. Nature. 2021 Academic Article GET IT
Times cited: 76
Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
Times cited: 21
The Tuberculosis Drug Accelerator at year 10: what have we learned?. Nature medicine. 2021 Academic Article GET IT
Times cited: 22
Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative. The Journal of clinical investigation. 2021 Academic Article GET IT
Times cited: 1
Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis. The Journal of experimental medicine. 2021 Academic Article GET IT
Times cited: 3
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity. ACS infectious diseases. 2021 Academic Article GET IT
Times cited: 1
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase. Cancer & metabolism. 2021 Academic Article GET IT
Times cited: 47
Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions. ACS infectious diseases. 2021 Academic Article GET IT
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nature communications. 2021 Academic Article GET IT
Times cited: 8
Metabolomics of Mycobacterium tuberculosis. Methods in molecular biology (Clifton, N.J.). 2021 Academic Article GET IT
Times cited: 8
Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis. Nature microbiology. 2020 Academic Article GET IT
Times cited: 7
Urinary biomarkers of mycobacterial load and treatment response in pulmonary tuberculosis. JCI insight. 2020 Academic Article GET IT
Times cited: 3
Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death. Molecular microbiology. 2020 Academic Article GET IT
Times cited: 15
The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP. PLoS genetics. 2020 Academic Article GET IT
Times cited: 27
Two interacting ATPases protect Mycobacterium tuberculosis from glycerol and nitric oxide toxicity. Journal of bacteriology. 2020 Academic Article GET IT
Times cited: 3
Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis. Nature communications. 2020 Academic Article GET IT
Times cited: 32
Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice. Cell metabolism. 2020 Academic Article GET IT
Times cited: 35
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents. Progress in biophysics and molecular biology. 2019 Review GET IT
Times cited: 15
Bacillus subtilis PgcA moonlights as a phosphoglucosamine mutase in support of peptidoglycan synthesis. PLoS genetics. 2019 Academic Article GET IT
Times cited: 7
Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline. Proceedings of the National Academy of Sciences of the United States of America. 2019 Academic Article GET IT
Times cited: 28
High-fructose corn syrup enhances intestinal tumor growth in mice. Science (New York, N.Y.). 2019 Academic Article GET IT
Times cited: 176
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition. Science (New York, N.Y.). 2019 Academic Article GET IT
Times cited: 46
Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027. PloS one. 2019 Academic Article GET IT
Times cited: 14
Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer. Cancers. 2019 Academic Article GET IT
Times cited: 65
Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA. mBio. 2018 Academic Article GET IT
Times cited: 31
Pyrazolo[1,5- a]pyridine Inhibitor of the Respiratory Cytochrome bcc Complex for the Treatment of Drug-Resistant Tuberculosis. ACS infectious diseases. 2018 Academic Article GET IT
Times cited: 59
Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis. Nature reviews. Microbiology. 2018 Review GET IT
Times cited: 105
Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy. 2018 Academic Article GET IT
Times cited: 69
Targeting protein biotinylation enhances tuberculosis chemotherapy. Science translational medicine. 2018 Academic Article GET IT
Times cited: 21
Mass Spectrometric Identification of Urinary Biomarkers of Pulmonary Tuberculosis. EBioMedicine. 2018 Academic Article GET IT
Times cited: 32
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization. ACS infectious diseases. 2018 Academic Article GET IT
Times cited: 39
Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface. mBio. 2018 Academic Article GET IT
Times cited: 41
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS infectious diseases. 2018 Academic Article GET IT
Times cited: 14
Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal. Molecular microbiology. 2017 Academic Article GET IT
Times cited: 8
Metabolism and the Evolution of Social Behavior. Molecular biology and evolution. 2017 Academic Article GET IT
Times cited: 12
Crosstalk between the tricarboxylic acid cycle and peptidoglycan synthesis in Caulobacter crescentus through the homeostatic control of α-ketoglutarate. PLoS genetics. 2017 Academic Article GET IT
Times cited: 39
Metabolic anticipation in Mycobacterium tuberculosis. Nature microbiology. 2017 Academic Article GET IT
Times cited: 57
A Tandem Liquid Chromatography-Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus. Journal of visualized experiments : JoVE. 2017 Academic Article GET IT
Times cited: 1
Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 64
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis. Cell chemical biology. 2017 Academic Article GET IT
Times cited: 34
Emerging Approaches to Tuberculosis Drug Development: At Home in the Metabolome. Trends in pharmacological sciences. 2017 Review GET IT
Times cited: 20
Metabolic Perspectives on Persistence. Microbiology spectrum. 2017 Review GET IT
Times cited: 8
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS infectious diseases. 2016 Academic Article GET IT
Times cited: 71
Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. ACS infectious diseases. 2016 Academic Article GET IT
Times cited: 49
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 2016 Academic Article GET IT
Times cited: 65
A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus. Molecular microbiology. 2016 Academic Article GET IT
Times cited: 58
Central Role of Pyruvate Kinase in Carbon Co-catabolism of Mycobacterium tuberculosis. The Journal of biological chemistry. 2016 Academic Article GET IT
Times cited: 31
Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell reports. 2016 Academic Article GET IT
Times cited: 95
Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase. Tuberculosis (Edinburgh, Scotland). 2015 Academic Article GET IT
Times cited: 4
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 2015 Academic Article GET IT
Times cited: 43
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. Journal of medicinal chemistry. 2015 Academic Article GET IT
Times cited: 36
Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis. Nature communications. 2015 Academic Article GET IT
Times cited: 42
Evolution of a thienopyrimidine antitubercular relying on medicinal chemistry and metabolomics insights. Tetrahedron letters. 2015 Academic Article GET IT
Times cited: 22
Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis. Cell. 2015 Academic Article GET IT
Times cited: 75
Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm. Cold Spring Harbor perspectives in medicine. 2015 Review GET IT
Times cited: 54
Mycobacterial genes essential for the pathogen's survival in the host. Immunological reviews. 2015 Review GET IT
Times cited: 40
Microbial Metabolomics: Fifty Shades of Metabolism. ACS infectious diseases. 2015 Academic Article GET IT
Times cited: 2
Metabolomics of Mycobacterium tuberculosis. Methods in molecular biology (Clifton, N.J.). 2015 Academic Article GET IT
Times cited: 29
Microbial metabolomics: innovation, application, insight. Current opinion in microbiology. 2014 Academic Article GET IT
Times cited: 52
Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis. Nature communications. 2014 Academic Article GET IT
Times cited: 198
Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis. Chemistry & biology. 2014 Academic Article GET IT
Times cited: 52
Metabolomics of Central Carbon Metabolism in Mycobacterium tuberculosis. Microbiology spectrum. 2014 Review GET IT
Times cited: 26
Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis. PLoS pathogens. 2014 Academic Article GET IT
Times cited: 56
Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 72
Intermediate-type vancomycin resistance (VISA) in genetically-distinct Staphylococcus aureus isolates is linked to specific, reversible metabolic alterations. PloS one. 2014 Academic Article GET IT
Times cited: 13
Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection. mBio. 2014 Academic Article GET IT
Times cited: 38
Risk factors and outcomes of infections caused by extremely drug-resistant gram-negative bacilli in patients hospitalized in intensive care units. American journal of infection control. 2014 Academic Article GET IT
Times cited: 30
Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 115
Allostery and compartmentalization: old but not forgotten. Current opinion in microbiology. 2014 Review GET IT
Times cited: 4
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 104
Minding the gaps: metabolomics mends functional genomics. EMBO reports. 2013 Comment GET IT
Times cited: 16
Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 211
Clinicians' knowledge, attitudes, and practices regarding infections with multidrug-resistant gram-negative bacilli in intensive care units. Infection control and hospital epidemiology. 2013 Academic Article GET IT
Times cited: 13
Glucose phosphorylation is required for Mycobacterium tuberculosis persistence in mice. PLoS pathogens. 2013 Academic Article GET IT
Times cited: 85
Mycobacterium tuberculosis metabolism and host interaction: mysteries and paradoxes. Current topics in microbiology and immunology. 2013 Review GET IT
Times cited: 49
Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis. Science (New York, N.Y.). 2012 Academic Article GET IT
Times cited: 152
Extended spectrum beta-lactamase-producing Enterobacteriaceae in international travelers and non-travelers in New York City. PloS one. 2012 Academic Article GET IT
Times cited: 44
Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum. The Journal of infectious diseases. 2012 Academic Article GET IT
Times cited: 37
Endemic Acinetobacter baumannii in a New York hospital. PloS one. 2011 Academic Article GET IT
Times cited: 13
Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS pathogens. 2011 Academic Article GET IT
Times cited: 116
Expression of the leptin receptor outside of bone marrow-derived cells regulates tuberculosis control and lung macrophage MHC expression. Journal of immunology (Baltimore, Md. : 1950). 2011 Academic Article GET IT
Times cited: 20
Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends in microbiology. 2011 Academic Article GET IT
Times cited: 126
Depletion of antibiotic targets has widely varying effects on growth. Proceedings of the National Academy of Sciences of the United States of America. 2011 Academic Article GET IT
Times cited: 123
Prevalence, persistence, and microbiology of Staphylococcus aureus nasal carriage among hemodialysis outpatients at a major New York Hospital. Diagnostic microbiology and infectious disease. 2011 Academic Article GET IT
Times cited: 21
On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis. Archives of biochemistry and biophysics. 2011 Academic Article GET IT
Times cited: 23
Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes. Cell host & microbe. 2011 Academic Article GET IT
Times cited: 96
Dispensability of surfactant proteins A and D in immune control of Mycobacterium tuberculosis infection following aerosol challenge of mice. Infection and immunity. 2011 Academic Article GET IT
Times cited: 20
Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis. ACS medicinal chemistry letters. 2011 Academic Article GET IT
Times cited: 91
Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates. Chemistry & biology. 2010 Academic Article GET IT
Times cited: 279
Metabolomics and malaria biology. Molecular and biochemical parasitology. 2010 Review GET IT
Times cited: 49
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy. Nature communications. 2010 Academic Article GET IT
Times cited: 207
Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 269
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase. Chemistry & biology. 2010 Academic Article GET IT
Times cited: 97
Clinical failure of vancomycin in a dialysis patient with methicillin-susceptible vancomycin-heteroresistant S. aureus. 2009 GET IT
Times cited: 15
Suitability of silica hydride stationary phase, aqueous normal phase chromatography for untargeted metabolomic profiling of Enterococcus faecium and Staphylococcus aureus. Journal of separation science. 2009 Academic Article GET IT
Times cited: 24
Tuberculosis and host metabolism: ancient associations, fresh insights. Translational research : the journal of laboratory and clinical medicine. 2009 Academic Article GET IT
Times cited: 6
Selective killing of nonreplicating mycobacteria. Cell host & microbe. 2008 Academic Article GET IT
Times cited: 151
An unusual cause of ST segment elevation. Brugada syndrome. 2006 GET IT
Decreasing in vitro susceptibility of clinical Staphylococcus aureus isolates to vancomycin at the New York Hospital: quantitative testing redux. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2005 Letter GET IT
Times cited: 35
S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 142
Antimicrobial mechanisms of cranberry juice. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2004 Letter GET IT
Times cited: 15
Clinical relevance of bacteriostatic versus bactericidal activity in the treatment of gram-positive bacterial infections. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2004 Letter GET IT
Times cited: 29
Priorities for the treatment of latent tuberculosis. The New England journal of medicine. 2004 Letter GET IT
Methicillin-resistant Staphylococcus aureus as a cause of antibiotic-associated diarrhea. Journal of clinical gastroenterology. 2004 Letter GET IT
Times cited: 13
Transcriptional coupling between the divergent promoters of a prototypic LysR-type regulatory system, the ilvYC operon of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 1999 Academic Article GET IT
Times cited: 62
Activation of gene expression by a ligand-induced conformational change of a protein-DNA complex. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 36
Leucine-responsive regulatory protein-DNA interactions in the leader region of the ilvGMEDA operon of Escherichia coli. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 32
Red 25, a protein that binds specifically to the sterol regulatory region in the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase. The Journal of biological chemistry. 1992 Academic Article GET IT
Times cited: 41

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Research

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Co-investigator Network

Funding awarded

Tri-I Stimulating Access to Research in Residency program (Tri-I StARR - NIAID) awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2023 - 2028
Transmission Aerobiology of M. tuberculosis: Genes and Metabolic Pathways That Sustain Mtb Across an Evolutionary Bottleneck awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2022 - 2026
Transmission Aerobiology of M. tuberculosis: Genes and Metabolic Pathways That Sustain Mtb Across an Evolutionary Bottleneck awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2021 - 2026
Weill Cornell Medicine Physician-Scientist Academy awarded by Burroughs Wellcome Fund Principal Investigator 2019 - 2024
Tri-I Training Program in Metabolomics awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2019 - 2024
Addgene 705011 awarded by Addgene, Inc. Principal Investigator 2022 - 2023
Metabolomics to identify synergistic TB targets awarded by Bill & Melinda Gates Foundation Principal Investigator 2020 - 2023

The role of PKM2 in dietary lipid absorption and fructose-induced obesity awarded by National Institute of Diabetes & Digestive & Kidney Diseases Co-Investigator 2022 - 2027
Molecular Mechanisms of Fructose-induced Colorectal Cancer Cell Survival awarded by National Cancer Institute Co-Investigator 2022 - 2026

Tri-Institutional Tuberculosis Research Advancement Center awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2022 - 2027
The Transmission Biology of Mycobacterium Tuberculosis awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2021 - 2026
Pathway Analysis in Tuberculosis awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2020 - 2025
Mining the biochemical dark matter of M. tuberculosis by high-throughput CRISPRi awarded by Howard Hughes Medical Institute Key Personnel 2019 - 2023

Defining the mechanism of coma in cerebral malaria awarded by National Heart, Lung, & Blood Institute Principal Investigator Subaward 2022 - 2027
Bacterial and Host Heterogeneity in TB latency, persistence and progression awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2022 - 2026
Metabolic determinants of Mtb virulence, vulnerability and variation - Core A awarded by National Heart, Lung, & Blood Institute Principal Investigator Subaward 2021 - 2026
Metabolic determinants of Mtb virulence, vulnerability and variation - Core B awarded by National Heart, Lung, & Blood Institute Principal Investigator Subaward 2021 - 2026
Metabolic determinants of Mtb virulence, vulnerability and variation - Project 2 awarded by National Heart, Lung, & Blood Institute Principal Investigator Subaward 2021 - 2026
Metabolic determinants of Mtb virulence, vulnerability and variation - Project 3 awarded by National Heart, Lung, & Blood Institute Principal Investigator Subaward 2021 - 2026
Bacteria and Host in TB Transmission awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2020 - 2025
Omics for TB: Response to Infection and Treatment awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2018 - 2024
Cytological Profiling to Rapidly Predict Drug Mechanism of Action Against M.tuberculosis awarded by Bill & Melinda Gates Foundation Principal Investigator Subaward 2021 - 2023

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Background

education and training

M.D., Ph.D., University of California, Irvine, School of Medicine 1999
B.S., Cornell University 1991

Contact

full name

Kyu Y. Rhee

primary email

kyr9001@med.cornell.edu

VIVO Weill Cornell Medical College

Kyu Y. Rhee Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email