The Biochemical journal

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Biochemical characterization of Plasmodium complement factors binding protein for its role in immune modulation.. 475. 2018
Structure, interactions and action of Mycobacterium tuberculosis 3-hydroxyisobutyric acid dehydrogenase.. 475. 2018
Protein-protein interaction studies reveal the Plasmodium falciparum merozoite surface protein-1 region involved in a complex formation that binds to human erythrocytes.. 475. 2018
Characterization of the catalytic properties of the membrane-anchored metalloproteinase ADAM9 in cell-based assays.. 474. 2017
Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment.. 473. 2016
Electrostatics and N-glycan-mediated membrane tethering of SCUBE1 is critical for promoting bone morphogenetic protein signalling.. 473. 2015
Glycosomal bromodomain factor 1 from Trypanosoma cruzi enhances trypomastigote cell infection and intracellular amastigote growth.. 473. 2015
Development of a new model system to dissect isoform specific Akt signalling in adipocytes.. 468. 2015
Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.. 464. 2014
Identification of interferon-γ as a new molecular target of liver X receptor.. 459. 2014
Tamoxifen inhibits macrophage FABP4 expression through the combined effects of the GR and PPARγ pathways.. 454. 2013
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins.. 452. 2013
Haem oxygenase-1 overexpression alters intracellular iron distribution.. 449. 2013
Target genes of the largest human SWI/SNF complex subunit control cell growth.. 434. 2011
Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs.. 421. 2009
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.. 420. 2009
Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies.. 413. 2008
Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A.. 394. 2006
Tid1 is a Smad-binding protein that can modulate Smad7 activity in developing embryos.. 393. 2006
Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein.. 388. 2005
Copper pathways in Plasmodium falciparum infected erythrocytes indicate an efflux role for the copper P-ATPase.. 381. 2004
Intracerebroventricular leptin regulates hepatic cholesterol metabolism.. 379. 2004
L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?. 376. 2003
Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues.. 373. 2003
Evidence for the interaction of the hereditary haemochromatosis protein, HFE, with the transferrin receptor in endocytic compartments.. 373. 2003
Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.. 373. 2003
The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2.. 369. 2003
Cathepsin B expression and down-regulation by gene silencing and antisense DNA in human chondrocytes.. 367. 2002
Differentiation regulates interleukin-1beta-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase.. 362. 2002
Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.. 361. 2002
Transforming growth factor-beta 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression.. 360. 2001
Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins.. 351 Pt 3. 2000
alpha2-macroglobulin modulates the immunoregulatory function of the lipocalin placental protein 14.. 351 Pt 2. 2000
Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis.. 350 Pt 3. 2000
Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28.. 348 Pt 1. 2000
Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE).. 347 Pt 1. 2000
Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.. 343 Pt 3. 1999
Salicylate-enhanced activation of transcription factors induced by interferon-gamma.. 342 Pt 3. 1999
Autocrine regulation of growth stimulation in human epithelial ovarian carcinoma by serine-proteinase-catalysed release of the urinary-type-plasminogen-activator N-terminal fragment.. 341 ( Pt 3). 1999
Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-zeta and C-lambda.. 337 ( Pt 3). 1999
Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice.. 336 ( Pt 1). 1998
Identification of endoplasmic reticulum proteins involved in glycan assembly: synthesis and characterization of P3-(4-azidoanilido)uridine 5'-triphosphate, a membrane-topological photoaffinity probe for uridine diphosphate-sugar binding proteins.. 333 ( Pt 3). 1998
Cloning and thermostability of TaqI endonuclease isoschizomers from Thermus species SM32 and Thermus filiformis Tok6A1.. 333 ( Pt 2). 1998
NADPH oxidase of chondrocytes contains an isoform of the gp91phox subunit.. 329 ( Pt 3). 1998
Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.. 310 ( Pt 2). 1995
Ethanol potentiates interleukin-1 beta-stimulated inducible nitric oxide synthase expression in cultured vascular smooth muscle cells.. 308 ( Pt 1). 1995
Haemin enhancement of glucose transport in human lymphocytes: stimulation of protein tyrosine phosphatase and activation of p56lck tyrosine kinase.. 291 ( Pt 1). 1993
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells.. 290 ( Pt 3). 1993
Activation of phospholipase D by alpha-thrombin or epidermal growth factor contributes to the formation of phosphatidic acid, but not to observed increases in 1,2-diacylglycerol.. 285 ( Pt 2). 1992
A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene.. 277 ( Pt 3). 1991
Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which 'buries' Ser-378, its site of phosphorylation by protein kinase A.. 274 ( Pt 2). 1991
Analysis of the physical state of cholesteryl esters in arterial-smooth-muscle-derived foam cells by differential scanning calorimetry.. 268. 1990
Sustained increase in 1,2-diacylglycerol precedes DNA synthesis in epidermal-growth-factor-stimulated fibroblasts. Evidence for stimulated phosphatidylcholine hydrolysis.. 267. 1990
1,2-Diacylglycerols overcome cyclic AMP-mediated inhibition of phosphatidylcholine synthesis in GH3 pituitary cells.. 267. 1990
Phospholipase C-mediated hydrolysis of phosphatidylcholine is activated by muscarinic agonists.. 263. 1989
delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals.. 262. 1989
The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells.. 259. 1989
Turnover of eicosanoid precursor fatty acids among phospholipid classes and subclasses of cultured human umbilical vein endothelial cells.. 258. 1989
Ca2+-induced changes in the secondary structure of a 60 kDa phosphoinositide-specific phospholipase C from bovine brain cytosol.. 255. 1988
Putrescine, a source of gamma-aminobutyric acid in the adrenal gland of the rat.. 251. 1988
Zymosan-induced release of inositol phosphates at resting cytosolic Ca2+ concentrations in macrophages.. 242. 1987
Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate.. 241. 1987
Determination of the molecular mass of apolipoprotein B-100. A chemical approach.. 239. 1986
Ionophore A23187 induces a refractory state in thrombin-activated release of inositol phosphates.. 238. 1986
Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event.. 237. 1986
Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures.. 235. 1986
Calcium signals and phospholipid methylation in eukaryotic cells.. 221. 1984
Elastin mRNA levels during foetal development of sheep nuchal ligament and lung. Hybridization to complementary and cloned DNA.. 220. 1984
Sheep elastin genes. Isolation and preliminary characterization of a 9.9-kilobase genomic clone.. 220. 1984
Large effects of preparative techniques on lymphocyte cyclic AMP content.. 216. 1983
Effects of polychlorinated biphenyl compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phenobarbital and iron on hepatic uroporphyrinogen decarboxylase. Implications for the pathogenesis of porphyria.. 214. 1983
The bivalent-cation dependence of phosphatidylinositol synthesis in a cell-free system from lymphocytes.. 212. 1983
Modulation of collagen production by fibroblasts. Effects of chronic exposure to agonists that increase intracellular cyclic AMP.. 204. 1982
Metal induction of haem oxygenase without concurrent degradation of cytochrome P-450. Protective effects of compound SKF 525A on the haem protein.. 202. 1982
Differential responses to inducers of delta-aminolaevulinate synthase and haem oxygenase during pregnancy.. 198. 1981
Metal ion interactions in the control of haem oxygenase induction in liver and kidney.. 192. 1980
Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds.. 190. 1980
Studies on the mechanism of induction of haem oxygenase by cobalt and other metal ions.. 154. 1976
Small-angle X-ray scattering of pig thyroglobulin in solution.. 143. 1974
A comparaive study of the effects of chemical modification on the immunochemical and optical properties of human plasma low-density lipoprotein(s) and apoproteins.. 133. 1973
Studies on the proteolytic activity of gamma-globulin preparations.. 102. 1967
Properties of a new glyoxylate reductase from leaves.. 84. 1962
The metabolism of C2 compounds in micro-organisms. 7. Preparation and properties of crystalline tartronic semialdehyde reductase.. 81. 1961
The metabolism of C2 compounds in micro-organisms. 6. Synthesis of cell constituents from glycollate by Pseudomonas sp.. 78. 1961
Extraction and recovery of inositol phosphates from tissues. 1987
Chloro-substituent sites and probability of co-planarity in polychlorinated biphenyls in determining uroporphyrin formation in cultured liver cells. 1986
Replication fork dynamics and the DNA damage response. 2012
Calreticulin: one protein, one gene, many functions. 1999
Signal transduction of stress via ceramide. 1998

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