Tomasz, Alexander

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Staphylococcus aureus Infecting and Colonizing Experimental Animals, Macaques, in a Research Animal Facility. Microbial drug resistance (Larchmont, N.Y.). 2018 Academic Article GET IT
Times cited: 3
Phenotypic signatures and genetic determinants of oxacillin tolerance in a laboratory mutant of Staphylococcus aureus. PloS one. 2018 Academic Article GET IT
Times cited: 9
Correction for Pardos de la Gandara et al., "Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus". Antimicrobial agents and chemotherapy. 2018 Academic Article GET IT
Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2018 Academic Article GET IT
Times cited: 16
Antibiotic Resistance as a Stress Response: Recovery of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus "Auxiliary" (fem) Mutants by Induction of the Stringent Stress Response. Antimicrobial agents and chemotherapy. 2017 Academic Article GET IT
Times cited: 14
Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice. Genome biology. 2017 Academic Article GET IT
Times cited: 162
Evolutionary Origin of the Staphylococcal Cassette Chromosome mec (SCCmec). Antimicrobial agents and chemotherapy. 2017 Academic Article GET IT
Times cited: 49
High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4). Antimicrobial agents and chemotherapy. 2017 Academic Article GET IT
Times cited: 39
Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci. PLoS genetics. 2017 Academic Article GET IT
Times cited: 55
Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene. Antimicrobial agents and chemotherapy. 2017 Academic Article GET IT
Times cited: 15
Heterogeneous oxacillin-resistant phenotypes and production of PBP2A by oxacillin-susceptible/mecA-positive MRSA strains from Africa. The Journal of antimicrobial chemotherapy. 2016 Academic Article GET IT
Times cited: 17
MRSA Causing Infections in Hospitals in Greater Metropolitan New York: Major Shift in the Dominant Clonal Type between 1996 and 2014. PloS one. 2016 Academic Article GET IT
Times cited: 21
Role of the Stringent Stress Response in the Antibiotic Resistance Phenotype of Methicillin-Resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2016 Academic Article GET IT
Times cited: 37
From the Bench to the Barbershop: Community Engagement to Raise Awareness About Community-Acquired Methicillin-Resistant Staphylococcus aureus and Hepatitis C Virus Infection. Progress in community health partnerships : research, education, and action. 2016 Academic Article GET IT
Times cited: 6
Ability of Antibiotic-Resistant Nonvaccine-Type Pneumococcal Clones to Cause Otitis Media in an Infant Mouse Model of Pneumococcal-Influenza Virus Coinfection. Microbial drug resistance (Larchmont, N.Y.). 2015 Academic Article GET IT
Times cited: 2
Molecular Types of Methicillin-Resistant Staphylococcus aureus and Methicillin-Sensitive S. aureus Strains Causing Skin and Soft Tissue Infections and Nasal Colonization, Identified in Community Health Centers in New York City. Journal of clinical microbiology. 2015 Academic Article GET IT
Times cited: 25
Recurrent furunculosis caused by a community-acquired Staphylococcus aureus strain belonging to the USA300 clone. Microbial drug resistance (Larchmont, N.Y.). 2015 Academic Article GET IT
Times cited: 8
Mechanisms of vancomycin resistance in Staphylococcus aureus. The Journal of clinical investigation. 2014 Review GET IT
Times cited: 317
Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone. BMC biology. 2014 Academic Article GET IT
Times cited: 56
Intermediate-type vancomycin resistance (VISA) in genetically-distinct Staphylococcus aureus isolates is linked to specific, reversible metabolic alterations. PloS one. 2014 Academic Article GET IT
Times cited: 13
Novel determinants of antibiotic resistance: identification of mutated loci in highly methicillin-resistant subpopulations of methicillin-resistant Staphylococcus aureus. mBio. 2014 Academic Article GET IT
Times cited: 59
The glucosaminidase domain of Atl - the major Staphylococcus aureus autolysin - has DNA-binding activity. MicrobiologyOpen. 2014 Academic Article GET IT
Times cited: 14
The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response. PloS one. 2013 Academic Article GET IT
Times cited: 71
Virulence potential and genome-wide characterization of drug resistant Streptococcus pneumoniae clones selected in vivo by the 7-valent pneumococcal conjugate vaccine. PloS one. 2013 Academic Article GET IT
Times cited: 13
Whole-genome sequencing reveals a link between β-lactam resistance and synthetases of the alarmone (p)ppGpp in Staphylococcus aureus. Microbial drug resistance (Larchmont, N.Y.). 2013 Academic Article GET IT
Times cited: 58
The use of whole genome sequencing to solve an epidemiological puzzle. EMBO molecular medicine. 2013 Comment GET IT
Times cited: 1
Alternative mutational pathways to intermediate resistance to vancomycin in methicillin-resistant Staphylococcus aureus. The Journal of infectious diseases. 2013 Academic Article GET IT
Times cited: 36
In vivo capsular switch in Streptococcus pneumoniae--analysis by whole genome sequencing. PloS one. 2012 Academic Article GET IT
Times cited: 21
Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 100
Guidelines for reporting novel mecA gene homologues. Antimicrobial agents and chemotherapy. 2012 Academic Article GET IT
Times cited: 136
Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300. PLoS pathogens. 2012 Academic Article GET IT
Times cited: 97
Identification of genetic determinants and enzymes involved with the amidation of glutamic acid residues in the peptidoglycan of Staphylococcus aureus. PLoS pathogens. 2012 Academic Article GET IT
Times cited: 75
Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. PloS one. 2011 Academic Article GET IT
Times cited: 20
Isolation and analysis of cell wall components from Streptococcus pneumoniae. Analytical biochemistry. 2011 Academic Article GET IT
Times cited: 70
Tackling antibiotic resistance. Nature reviews. Microbiology. 2011 Review GET IT
Times cited: 788
The CEM-NET initiative: molecular biology and epidemiology in alliance--tracking antibiotic-resistant staphylococci and pneumococci in hospitals and in the community. International journal of medical microbiology : IJMM. 2011 Review GET IT
Times cited: 3
Rapid pneumococcal evolution in response to clinical interventions. Science (New York, N.Y.). 2011 Academic Article GET IT
Times cited: 680
Antimicrobials. Current opinion in microbiology. 2010 Editorial Article GET IT
Times cited: 2
Role of teichoic acid choline moieties in the virulence of Streptococcus pneumoniae. Infection and immunity. 2009 Academic Article GET IT
Times cited: 15
Evidence for a dual role of PBP1 in the cell division and cell separation of Staphylococcus aureus. Molecular microbiology. 2009 Academic Article GET IT
Times cited: 47
Reconstruction of the phenotypes of methicillin-resistant Staphylococcus aureus by replacement of the staphylococcal cassette chromosome mec with a plasmid-borne copy of Staphylococcus sciuri pbpD gene. Antimicrobial agents and chemotherapy. 2008 Academic Article GET IT
Times cited: 34
Different pathways of choline metabolism in two choline-independent strains of Streptococcus pneumoniae and their impact on virulence. Journal of bacteriology. 2008 Academic Article GET IT
Times cited: 16
Comparative study of the susceptibilities of major epidemic clones of methicillin-resistant Staphylococcus aureus to oxacillin and to the new broad-spectrum cephalosporin ceftobiprole. Antimicrobial agents and chemotherapy. 2008 Academic Article GET IT
Times cited: 28
Essential role of choline for pneumococcal virulence in an experimental model of meningitis. Journal of internal medicine. 2008 Academic Article GET IT
Times cited: 20
Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan. The Journal of biological chemistry. 2007 Academic Article GET IT
Times cited: 69
Role of a sodium-dependent symporter homologue in the thermosensitivity of beta-lactam antibiotic resistance and cell wall composition in Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2007 Academic Article GET IT
Times cited: 5
Penicillin-binding proteins and cell wall composition in beta-lactam-sensitive and -resistant strains of Staphylococcus sciuri. Journal of bacteriology. 2007 Academic Article GET IT
Times cited: 24
Antibiotic resistant Staphylococcus aureus: a paradigm of adaptive power. Current opinion in microbiology. 2007 Review GET IT
Times cited: 211
Perturbation of cell wall synthesis suppresses autolysis in Staphylococcus aureus: evidence for coregulation of cell wall synthetic and hydrolytic enzymes. Journal of bacteriology. 2007 Academic Article GET IT
Times cited: 41
The essential tacF gene is responsible for the choline-dependent growth phenotype of Streptococcus pneumoniae. Journal of bacteriology. 2007 Academic Article GET IT
Times cited: 43
Fluorescence ratio imaging microscopy shows decreased access of vancomycin to cell wall synthetic sites in vancomycin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2007 Academic Article GET IT
Times cited: 65
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proceedings of the National Academy of Sciences of the United States of America. 2007 Academic Article GET IT
Times cited: 438
Role of PBP1 in cell division of Staphylococcus aureus. Journal of bacteriology. 2007 Academic Article GET IT
Times cited: 79
Extensive and genome-wide changes in the transcription profile of Staphylococcus aureus induced by modulating the transcription of the cell wall synthesis gene murF. Journal of bacteriology. 2006 Academic Article GET IT
Times cited: 61
Role of VraSR in antibiotic resistance and antibiotic-induced stress response in Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2006 Academic Article GET IT
Times cited: 129
A link in transcription between the native pbpB and the acquired mecA gene in a strain of Staphylococcus aureus. Microbiology (Reading, England). 2006 Academic Article GET IT
Times cited: 12
Attenuation of penicillin resistance in a peptidoglycan O-acetyl transferase mutant of Streptococcus pneumoniae. Molecular microbiology. 2006 Academic Article GET IT
Times cited: 85
Drastic reduction in the virulence of Streptococcus pneumoniae expressing type 2 capsular polysaccharide but lacking choline residues in the cell wall. Molecular microbiology. 2006 Academic Article GET IT
Times cited: 40
Role of murF in cell wall biosynthesis: isolation and characterization of a murF conditional mutant of Staphylococcus aureus. Journal of bacteriology. 2006 Academic Article GET IT
Times cited: 38
Inhibition of the autolytic system by vancomycin causes mimicry of vancomycin-intermediate Staphylococcus aureus-type resistance, cell concentration dependence of the MIC, and antibiotic tolerance in vancomycin-susceptible S. aureus. Antimicrobial agents and chemotherapy. 2006 Academic Article GET IT
Times cited: 47
Overexpression of genes of the cell wall stimulon in clinical isolates of Staphylococcus aureus exhibiting vancomycin-intermediate- S. aureus-type resistance to vancomycin. Journal of bacteriology. 2006 Academic Article GET IT
Times cited: 172
Microbiology. Weapons of microbial drug resistance abound in soil flora. Science (New York, N.Y.). 2006 Comment GET IT
Times cited: 22
High-level (beta)-lactam resistance and cell wall synthesis catalyzed by the mecA homologue of Staphylococcus sciuri introduced into Staphylococcus aureus. Journal of bacteriology. 2005 Academic Article GET IT
Times cited: 12
Genome sequencing in microfabricated high-density picolitre reactors. Nature. 2005 Academic Article GET IT
Times cited: 6028
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway. EMBO reports. 2005 Academic Article GET IT
Times cited: 92
Role of penicillin-binding protein 2 (PBP2) in the antibiotic susceptibility and cell wall cross-linking of Staphylococcus aureus: evidence for the cooperative functioning of PBP2, PBP4, and PBP2A. Journal of bacteriology. 2005 Academic Article GET IT
Times cited: 127
Expression of high-level methicillin resistance in Staphylococcus aureus from the Staphylococcus sciuri mec A homologue: role of mutation(s) in the genetic background and in the coding region of mec A. Microbial drug resistance (Larchmont, N.Y.). 2005 Academic Article GET IT
Times cited: 7
Serotypes and clonal types of penicillin-susceptible streptococcus pneumoniae causing invasive disease in children in five Latin American countries. Microbial drug resistance (Larchmont, N.Y.). 2005 Academic Article GET IT
Times cited: 25
Penicillin-binding protein 2 is essential for expression of high-level vancomycin resistance and cell wall synthesis in vancomycin-resistant Staphylococcus aureus carrying the enterococcal vanA gene complex. Antimicrobial agents and chemotherapy. 2004 Academic Article GET IT
Times cited: 43
The challenge of antibiotic resistant bacterial pathogens: the medical need, the market and prospects for new antimicrobial agents. Current opinion in microbiology. 2004 Editorial Article GET IT
Times cited: 44
Role of murE in the Expression of beta-lactam antibiotic resistance in Staphylococcus aureus. Journal of bacteriology. 2004 Academic Article GET IT
Times cited: 39
International clones of methicillin-resistant Staphylococcus aureus in two hospitals in Miami, Florida. Journal of clinical microbiology. 2004 Academic Article GET IT
Times cited: 77
The structure of the cell wall peptidoglycan of Bacillus cereus RSVF1, a strain closely related to Bacillus anthracis. Microbial drug resistance (Larchmont, N.Y.). 2004 Academic Article GET IT
Times cited: 23
Alterations of cell wall structure and metabolism accompany reduced susceptibility to vancomycin in an isogenic series of clinical isolates of Staphylococcus aureus. Journal of bacteriology. 2003 Academic Article GET IT
Times cited: 155
Cell wall branches, penicillin resistance and the secrets of the MurM protein. Trends in microbiology. 2003 Academic Article GET IT
Times cited: 35
High level oxacillin and vancomycin resistance and altered cell wall composition in Staphylococcus aureus carrying the staphylococcal mecA and the enterococcal vanA gene complex. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 87
EURISWEB--Web-based epidemiological surveillance of antibiotic-resistant pneumococci in day care centers. BMC medical informatics and decision making. 2003 Academic Article GET IT
Times cited: 11
Inactivation of the srtA gene affects localization of surface proteins and decreases adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro. Infection and immunity. 2003 Academic Article GET IT
Times cited: 113
Evolution of a vancomycin-intermediate Staphylococcus aureus strain in vivo: multiple changes in the antibiotic resistance phenotypes of a single lineage of methicillin-resistant S. aureus under the impact of antibiotics administered for chemotherapy. Journal of clinical microbiology. 2003 Academic Article GET IT
Times cited: 118
"Intelligence coup" for drug designers: crystal structure of Staphylococcus aureus beta-lactam resistance protein PBP2A. Lancet (London, England). 2003 Academic Article GET IT
Times cited: 5
Development of methicillin resistance in clinical isolates of Staphylococcus sciuri by transcriptional activation of the mecA homologue native to s. Journal of bacteriology. 2003 Academic Article GET IT
Times cited: 76
Frequent recovery of a single clonal type of multidrug-resistant Staphylococcus aureus from patients in two hospitals in Taiwan and China. Journal of clinical microbiology. 2003 Academic Article GET IT
Times cited: 122
Normally functioning murF is essential for the optimal expression of methicillin resistance in Staphylococcus aureus. Microbial drug resistance (Larchmont, N.Y.). 2003 Academic Article GET IT
Times cited: 44
X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus. Proteins. 2003 Academic Article GET IT
Times cited: 17
From ecological reservoir to disease: the nasopharynx, day-care centres and drug-resistant clones of Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy. 2002 Review GET IT
Times cited: 76
Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae. Infection and immunity. 2002 Academic Article GET IT
Times cited: 101
Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor. Structure (London, England : 1993). 2002 Academic Article GET IT
Times cited: 54
Pilot study of the genetic diversity of the pneumococcal nasopharyngeal flora among children attending day care centers. Journal of clinical microbiology. 2002 Academic Article GET IT
Times cited: 26
Diversity of penicillin-nonsusceptible Streptococcus pneumoniae circulating in Iceland after the introduction of penicillin-resistant clone Spain(6B)-2. The Journal of infectious diseases. 2002 Academic Article GET IT
Times cited: 20
Secrets of success of a human pathogen: molecular evolution of pandemic clones of meticillin-resistant Staphylococcus aureus. The Lancet. Infectious diseases. 2002 Review GET IT
Times cited: 420
The murMN operon: a functional link between antibiotic resistance and antibiotic tolerance in Streptococcuspneumoniae. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
Times cited: 57
Complementation of the essential peptidoglycan transpeptidase function of penicillin-binding protein 2 (PBP2) by the drug resistance protein PBP2A in Staphylococcus aureus. Journal of bacteriology. 2001 Academic Article GET IT
Times cited: 159
High rates of multiple antibiotic resistance in Streptococcus pneumoniae from healthy children living in isolated rural communities: association with cephalosporin use and intrafamilial transmission. Pediatrics. 2001 Academic Article GET IT
Times cited: 99
Multilocus sequence typing of Streptococcus pneumoniae clones with unusual drug resistance patterns: genetic backgrounds and relatedness to other epidemic clones. The Journal of infectious diseases. 2001 Academic Article GET IT
Times cited: 38
Functional analysis of Streptococcus pneumoniae MurM reveals the region responsible for its specificity in the synthesis of branched cell wall peptides. The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 29
An acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococci. Proceedings of the National Academy of Sciences of the United States of America. 2001 Academic Article GET IT
Times cited: 274
The evolution of methicillin resistance in Staphylococcus aureus: similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones. Proceedings of the National Academy of Sciences of the United States of America. 2001 Academic Article GET IT
Times cited: 252
Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. Journal of clinical microbiology. 2001 Academic Article GET IT
Times cited: 447
Recruitment of the mecA gene homologue of Staphylococcus sciuri into a resistance determinant and expression of the resistant phenotype in Staphylococcus aureus. Journal of bacteriology. 2001 Academic Article GET IT
Times cited: 138
Identification of the teichoic acid phosphorylcholine esterase in Streptococcus pneumoniae. Molecular microbiology. 2001 Academic Article GET IT
Times cited: 50
Penicillin-resistant Streptococcus pneumoniae in metropolitan New York hospitals: case control study and molecular typing of resistant isolates. Microbial drug resistance (Larchmont, N.Y.). 2001 Academic Article GET IT
Times cited: 6
The evolution of pandemic clones of methicillin-resistant Staphylococcus aureus: identification of two ancestral genetic backgrounds and the associated mec elements. Microbial drug resistance (Larchmont, N.Y.). 2001 Academic Article GET IT
Times cited: 259
The role of murMN operon in penicillin resistance and antibiotic tolerance of Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.). 2001 Academic Article GET IT
Times cited: 18
Distribution of the mosaic structured murM genes among natural populations of Streptococcus pneumoniae. Journal of bacteriology. 2000 Academic Article GET IT
Times cited: 39
Genetic diversity and clonal patterns among antibiotic-susceptible and -resistant Streptococcus pneumoniae colonizing children: day care centers as autonomous epidemiological units. Journal of clinical microbiology. 2000 Academic Article GET IT
Times cited: 77
Characterization of the murMN operon involved in the synthesis of branched peptidoglycan peptides in Streptococcus pneumoniae. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 52
Carriage of internationally spread clones of Streptococcus pneumoniae with unusual drug resistance patterns in children attending day care centers in Lisbon, Portugal. The Journal of infectious diseases. 2000 Academic Article GET IT
Times cited: 80
The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniae. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 212
Inhibition of the expression of penicillin resistance in Streptococcus pneumoniae by inactivation of cell wall muropeptide branching genes. Proceedings of the National Academy of Sciences of the United States of America. 2000 Academic Article GET IT
Times cited: 147
Characterization of Staphylococcus aureus cell wall glycan strands, evidence for a new beta-N-acetylglucosaminidase activity. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 95
Molecular evolution in a multidrug-resistant lineage of Streptococcus pneumoniae: emergence of strains belonging to the serotype 6B Icelandic clone that lost antibiotic resistance traits. Journal of clinical microbiology. 2000 Academic Article GET IT
Times cited: 32
Molecular typing of Streptococcus pneumoniae in northeastern Romania: unique clones of S. pneumoniae isolated from children hospitalized for infections and from healthy and human immunodeficiency virus-infected children in the community. The Journal of infectious diseases. 2000 Academic Article GET IT
Times cited: 17
Cloning, characterization, and inactivation of the gene pbpC, encoding penicillin-binding protein 3 of Staphylococcus aureus. Journal of bacteriology. 2000 Academic Article GET IT
Times cited: 60
Distribution of methicillin-resistant Staphylococcus aureus clones among health care facilities in Connecticut, New Jersey, and Pennsylvania. Microbial drug resistance (Larchmont, N.Y.). 2000 Academic Article GET IT
Times cited: 37
Molecular typing of methicillin-resistant Staphylococcus aureus by pulsed-field gel electrophoresis: comparison of results obtained in a multilaboratory effort using identical protocols and MRSA strains. Microbial drug resistance (Larchmont, N.Y.). 2000 Academic Article GET IT
Times cited: 257
Patterns of multidrug resistance among methicillin-resistant hospital isolates of coagulase-positive and coagulase-negative staphylococci collected in the international multicenter study RESIST in 1997 and 1998. Microbial drug resistance (Larchmont, N.Y.). 2000 Academic Article GET IT
Times cited: 81
Similarity of antibiotic resistance patterns and molecular typing properties of methicillin-resistant Staphylococcus aureus isolates widely spread in hospitals in New York City and in a hospital in Tokyo, Japan. Microbial drug resistance (Larchmont, N.Y.). 2000 Academic Article GET IT
Times cited: 78
Gradual alterations in cell wall structure and metabolism in vancomycin-resistant mutants of Staphylococcus aureus. Journal of bacteriology. 1999 Academic Article GET IT
Times cited: 100
Prophage carriage as a molecular epidemiological marker in Streptococcus pneumoniae. Journal of clinical microbiology. 1999 Academic Article GET IT
Times cited: 13
A multinational workshop on drug-resistant pathogens of the respiratory tract: prevalence, risk factors and intervention strategies. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1999 Academic Article GET IT
Carriage and antibiotic resistance of respiratory pathogens and molecular epidemiology of antibiotic-resistant Streptococcus pneumoniae colonizing children in day-care centers in Lisbon: the Portuguese day-care center initiative. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1999 Academic Article GET IT
The challenge of multiresistant Streptococcus pneumoniae: international initiatives in day-care centers and the use of molecular epidemiologic techniques. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1999 Academic Article GET IT
Times cited: 9
New faces of an old pathogen: emergence and spread of multidrug-resistant Streptococcus pneumoniae. The American journal of medicine. 1999 Review GET IT
Times cited: 60
Inactivated pbp4 in highly glycopeptide-resistant laboratory mutants of Staphylococcus aureus. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 106
A high incidence of prophage carriage among natural isolates of Streptococcus pneumoniae. Journal of bacteriology. 1999 Academic Article GET IT
Times cited: 58
Molecular characterization of penicillin-resistant Streptococcus pneumoniae isolates from Bulgaria. Journal of clinical microbiology. 1999 Academic Article GET IT
Times cited: 30
The development of vancomycin resistance in a patient with methicillin-resistant Staphylococcus aureus infection. 1999 GET IT
Times cited: 598
Acquisition of new capsular genes among clinical isolates of antibiotic-resistant Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.). 1999 Academic Article GET IT
Times cited: 25
Antibiotic resistance as a stress response: complete sequencing of a large number of chromosomal loci in Staphylococcus aureus strain COL that impact on the expression of resistance to methicillin. Microbial drug resistance (Larchmont, N.Y.). 1999 Academic Article GET IT
Times cited: 126
Carriage of respiratory tract pathogens and molecular epidemiology of Streptococcus pneumoniae colonization in healthy children attending day care centers in Lisbon, Portugal. Microbial drug resistance (Larchmont, N.Y.). 1999 Academic Article GET IT
Times cited: 99
Heterogeneously vancomycin-resistant Staphylococcus epidermidis strain causing recurrent peritonitis in a dialysis patient during vancomycin therapy. 1999 GET IT
Times cited: 64
Inactivation of the methicillin resistance gene mecA in vancomycin-resistant Staphylococcus aureus. Microbial drug resistance (Larchmont, N.Y.). 1999 Academic Article GET IT
Times cited: 67
Role of transposon Tn5482 in the epidemiology of vancomycin-resistant Enterococcus faecium in the pediatric oncology unit of a New York City Hospital. Microbial drug resistance (Larchmont, N.Y.). 1999 Academic Article GET IT
Times cited: 39
The Staphylococcus aureus transposon Tn551: complete nucleotide sequence and transcriptional analysis of the expression of the erythromycin resistance gene. Microbial drug resistance (Larchmont, N.Y.). 1999 Academic Article GET IT
Times cited: 25
Transcriptional analysis of the Staphylococcus aureus penicillin binding protein 2 gene. Journal of bacteriology. 1998 Academic Article GET IT
Times cited: 34
Molecular characterization of the complete 23F capsular polysaccharide locus of Streptococcus pneumoniae. Journal of bacteriology. 1998 Academic Article GET IT
Times cited: 34
Molecular epidemiology of penicillin-resistant Streptococcus pneumoniae isolates recovered in Italy from 1993 to 1996. Journal of clinical microbiology. 1998 Academic Article GET IT
Times cited: 66
Molecular epidemiology of methicillin-resistant Staphylococcus aureus in 12 New York hospitals. MRSA Collaborative Study Group. The Journal of infectious diseases. 1998 Academic Article GET IT
Times cited: 153
Accelerated evolution: emergence of multidrug resistant gram-positive bacterial pathogens in the 1990's. The Netherlands journal of medicine. 1998 Academic Article GET IT
Times cited: 10
Why have group A streptococci remained susceptible to penicillin? Report on a symposium. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 1998 Conference Paper GET IT
Times cited: 103
Recurrent peritonitis in a patient on dialysis and prophylactic vancomycin. Lancet (London, England). 1998 Letter GET IT
Times cited: 20
Antibacterial efficacy of nisin against multidrug-resistant Gram-positive pathogens. The Journal of antimicrobial chemotherapy. 1998 Academic Article GET IT
Times cited: 162
Capsular transformation of a multidrug-resistant Streptococcus pneumoniae in vivo. The Journal of infectious diseases. 1998 Academic Article GET IT
Times cited: 125
Low-level teicoplanin resistance and heteroresistance to vancomycin. Annals of internal medicine. 1998 Letter GET IT
Times cited: 7
Decreased susceptibilities to teicoplanin and vancomycin among coagulase-negative methicillin-resistant clinical isolates of staphylococci. Antimicrobial agents and chemotherapy. 1998 Academic Article GET IT
Times cited: 122
Genetic organization of the mecA region in methicillin-susceptible and methicillin-resistant strains of Staphylococcus sciuri. Journal of bacteriology. 1998 Academic Article GET IT
Times cited: 61
Geographic distribution of penicillin resistance of Streptococcus pneumoniae in Brazil: genetic relatedness. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 35
Molecular characterization of penicillin-resistant Streptococcus pneumoniae isolates causing respiratory disease in the United States. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 141
Molecular epidemiologic characterization of penicillin-resistant Streptococcus pneumoniae invasive pediatric isolates recovered in six Latin-American countries: an overview. PAHO/Rockefeller University Workshop. Pan American Health Organization. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 73
Penicillin-resistant Streptococcus pneumoniae in Argentina: frequent occurrence of an internationally spread serotype 14 clone. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 24
Penicillin-resistant Streptococcus pneumoniae in Colombia: presence of international epidemic clones. Colombian pneumococcal study group. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 22
Predominance of the multiresistant 23F international clone of Streptococcus pneumoniae among isolates from Mexico. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 22
Suppression of glycopeptide resistance in a highly teicoplanin-resistant mutant of Staphylococcus aureus by transposon inactivation of genes involved in cell wall synthesis. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 39
The apparent importation of penicillin-resistant capsular type 14 Spanish/French clone of Streptococcus pneumoniae into Uruguay in the early 1990s. Microbial drug resistance (Larchmont, N.Y.). 1998 Academic Article GET IT
Times cited: 23
Structural characterization of an abnormally cross-linked muropeptide dimer that is accumulated in the peptidoglycan of methicillin- and cefotaxime-resistant mutants of Staphylococcus aureus. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 25
The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase. Journal of bacteriology. 1997 Academic Article GET IT
Times cited: 55
Wide geographic distribution of a unique methicillin-resistant Staphylococcus aureus clone in Hungarian hospitals. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1997 Academic Article GET IT
Times cited: 75
Activity of quinupristin/dalfopristin against Streptococcus pneumoniae in vitro and in vivo in the rabbit model of experimental meningitis. The Journal of antimicrobial chemotherapy. 1997 Academic Article GET IT
Times cited: 22
Suppression of beta-lactam antibiotic resistance in a methicillin-resistant Staphylococcus aureus through synergic action of early cell wall inhibitors and some other antibiotics. The Journal of antimicrobial chemotherapy. 1997 Academic Article GET IT
Times cited: 64
Inhibition of cell wall turnover and autolysis by vancomycin in a highly vancomycin-resistant mutant of Staphylococcus aureus. Journal of bacteriology. 1997 Academic Article GET IT
Times cited: 234
Ribotype delineation and description of Staphylococcus sciuri subspecies and their potential as reservoirs of methicillin resistance and staphylolytic enzyme genes. International journal of systematic bacteriology. 1997 Academic Article GET IT
Times cited: 66
Abnormal physiological properties and altered cell wall composition in Streptococcus pneumoniae grown in the presence of clavulanic acid. Antimicrobial agents and chemotherapy. 1997 Academic Article GET IT
Times cited: 35
Antibiotic resistance in Streptococcus pneumoniae. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 1997 Review GET IT
Times cited: 218
Autolysis and cell wall degradation in a choline-independent strain of Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.). 1997 Academic Article GET IT
Times cited: 41
Spread of the serotype 23F multidrug-resistant Streptococcus pneumoniae clone to South Korea. Microbial drug resistance (Larchmont, N.Y.). 1997 Academic Article GET IT
Times cited: 29
Ubiquitous distribution of the competence related genes comA and comC among isolates of Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.). 1997 Academic Article GET IT
Times cited: 33
Sigma-B, a putative operon encoding alternate sigma factor of Staphylococcus aureus RNA polymerase: molecular cloning and DNA sequencing. Journal of bacteriology. 1996 Academic Article GET IT
Times cited: 195
A highly vancomycin-resistant laboratory mutant of Staphylococcus aureus. FEMS microbiology letters. 1996 Academic Article GET IT
Times cited: 53
Methicillin-resistant Staphylococcus aureus isolates recovered from a New York City hospital: analysis by molecular fingerprinting techniques. Journal of clinical microbiology. 1996 Academic Article GET IT
Times cited: 43
Separation of abnormal cell wall composition from penicillin resistance through genetic transformation of Streptococcus pneumoniae. Journal of bacteriology. 1996 Academic Article GET IT
Times cited: 31
A phosphoglucomutase-like gene essential for the optimal expression of methicillin resistance in Staphylococcus aureus: molecular cloning and DNA sequencing. Microbial drug resistance (Larchmont, N.Y.). 1996 Academic Article GET IT
Times cited: 53
Multiplicity of genetic backgrounds among vancomycin-resistant Enterococcus faecium isolates recovered from an outbreak in a New York City hospital. Microbial drug resistance (Larchmont, N.Y.). 1996 Academic Article GET IT
Times cited: 39
Naturally occurring peptidoglycan variants of Streptococcus pneumoniae. Journal of bacteriology. 1996 Academic Article GET IT
Times cited: 68
Testing the efficacy of a molecular surveillance network: methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VREF) genotypes in six hospitals in the metropolitan New York City area. The BARG Initiative Pilot Study Group. Bacterial Antibiotic Resistance Group. Microbial drug resistance (Larchmont, N.Y.). 1996 Academic Article GET IT
Times cited: 46
Tracking the evolutionary origin of the methicillin resistance gene: cloning and sequencing of a homologue of mecA from a methicillin susceptible strain of Staphylococcus sciuri. Microbial drug resistance (Larchmont, N.Y.). 1996 Academic Article GET IT
Times cited: 153
Ubiquitous presence of a mecA homologue in natural isolates of Staphylococcus sciuri. Microbial drug resistance (Larchmont, N.Y.). 1996 Academic Article GET IT
Times cited: 145
Geographic spread of epidemic multiresistant Staphylococcus aureus clone in Brazil. Journal of clinical microbiology. 1995 Academic Article GET IT
Times cited: 194
The pneumococcus at the gates. The New England journal of medicine. 1995 Editorial Article GET IT
Times cited: 74
Drastic changes in the peptidoglycan composition of penicillin resistant laboratory mutants of Streptococcus pneumoniae. FEMS microbiology letters. 1995 Academic Article GET IT
Times cited: 19
Selective lysis of cultures and cell walls of penicillin-resistant but not penicillin-susceptible Streptococcus pneumoniae strains by a murein hydrolase complex. Journal of bacteriology. 1995 Academic Article GET IT
Times cited: 4
Evidence for the geographic spread of a methicillin-resistant Staphylococcus aureus clone between Portugal and Spain. Journal of clinical microbiology. 1995 Academic Article GET IT
Times cited: 117
Transmission of multidrug-resistant serotype 23F Streptococcus pneumoniae in group day care: evidence suggesting capsular transformation of the resistant strain in vivo. The Journal of infectious diseases. 1995 Academic Article GET IT
Times cited: 161
A Staphylococcus aureus autolysin that has an N-acetylmuramoyl-L-alanine amidase domain and an endo-beta-N-acetylglucosaminidase domain: cloning, sequence analysis, and characterization. Proceedings of the National Academy of Sciences of the United States of America. 1995 Academic Article GET IT
Times cited: 245
Antibiotic susceptibility of Streptococcus pneumoniae isolates in Portugal. A multicenter study between 1989 and 1993. Microbial drug resistance (Larchmont, N.Y.). 1995 Academic Article GET IT
Times cited: 43
Beta-Lactam antibiotic resistance in gram-positive bacterial pathogens of the upper respiratory tract: a brief overview of mechanisms. Microbial drug resistance (Larchmont, N.Y.). 1995 Review GET IT
Times cited: 29
Novel penicillin-resistant clones of Streptococcus pneumoniae in the Czech Republic and in Slovakia. Microbial drug resistance (Larchmont, N.Y.). 1995 Academic Article GET IT
Times cited: 58
Penicillin-resistant and multidrug-resistant Streptococcus pneumoniae in a pediatric hospital in Zagreb, Croatia. Microbial drug resistance (Larchmont, N.Y.). 1995 Academic Article GET IT
Times cited: 20
The prospects of treatment failure in the chemotherapy of infectious diseases in the 1990s. Microbial drug resistance (Larchmont, N.Y.). 1995 Editorial Article GET IT
Times cited: 23
Reduced methicillin resistance in a new Staphylococcus aureus transposon mutant that incorporates muramyl dipeptides into the cell wall peptidoglycan. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 58
Reassessment of the number of auxiliary genes essential for expression of high-level methicillin resistance in Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1994 Academic Article GET IT
Times cited: 175
Benefit and risk in the beta-lactam antibiotic-resistance strategies of Streptococcus pneumoniae and Staphylococcus aureus. Trends in microbiology. 1994 Academic Article GET IT
Times cited: 19
CD14 is a pattern recognition receptor. Immunity. 1994 Academic Article GET IT
Times cited: 625
Mechanisms of brain injury in bacterial meningitis: workshop summary. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 1994 Conference Paper GET IT
Times cited: 73
Spread and maintenance of a dominant methicillin-resistant Staphylococcus aureus (MRSA) clone during an outbreak of MRSA disease in a Spanish hospital. Journal of clinical microbiology. 1994 Academic Article GET IT
Times cited: 172
Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes. Infection and immunity. 1994 Academic Article GET IT
Times cited: 297
Multiple-antibiotic-resistant pathogenic bacteria. A report on the Rockefeller University Workshop. The New England journal of medicine. 1994 Academic Article GET IT
Times cited: 392
Methylprednisolone attenuates inflammation, increase of brain water content and intracranial pressure, but does not influence cerebral blood flow changes in experimental pneumococcal meningitis. Brain research. 1994 Academic Article GET IT
Times cited: 19
Methicillin-resistant Staphylococcus aureus disease in a Portuguese hospital: characterization of clonal types by a combination of DNA typing methods. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1994 Academic Article GET IT
Times cited: 150
Molecular aspects of methicillin resistance in Staphylococcus aureus. The Journal of antimicrobial chemotherapy. 1994 Review GET IT
Times cited: 157
The peptidoglycan composition of a Staphylococcus aureus mutant selected for reduced methicillin resistance. The Journal of biological chemistry. 1993 Academic Article GET IT
Times cited: 33
Evidence for the introduction of a multiresistant clone of serotype 6B Streptococcus pneumoniae from Spain to Iceland in the late 1980s. The Journal of infectious diseases. 1993 Academic Article GET IT
Times cited: 296
Altered muropeptide composition in Staphylococcus aureus strains with an inactivated femA locus. Journal of bacteriology. 1993 Academic Article GET IT
Times cited: 77
Possible role of a choline-containing teichoic acid in the maintenance of normal cell shape and physiology in Streptococcus oralis. Journal of bacteriology. 1993 Academic Article GET IT
Times cited: 41
Triggering of pneumococcal autolysis by lysozyme. The Journal of infectious diseases. 1993 Academic Article GET IT
Times cited: 29
Abnormal peptidoglycan produced in a methicillin-resistant strain of Staphylococcus aureus grown in the presence of methicillin: functional role for penicillin-binding protein 2A in cell wall synthesis. Antimicrobial agents and chemotherapy. 1993 Academic Article GET IT
Times cited: 88
Genetic control of population structure in heterogeneous strains of methicillin resistant Staphylococcus aureus. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1993 Academic Article GET IT
Times cited: 47
Antioxidants attenuate microvascular changes in the early phase of experimental pneumococcal meningitis in rats. Stroke. 1992 Academic Article GET IT
Times cited: 66
Altered murein composition in a DD-carboxypeptidase mutant of Streptococcus pneumoniae. Journal of bacteriology. 1992 Academic Article GET IT
Times cited: 34
Isolation and characterization of a Tn551-autolysis mutant of Staphylococcus aureus. Journal of bacteriology. 1992 Academic Article GET IT
Times cited: 78
Geographic distribution of penicillin-resistant clones of Streptococcus pneumoniae: characterization by penicillin-binding protein profile, surface protein A typing, and multilocus enzyme analysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 1992 Academic Article GET IT
Times cited: 158
Transforming growth factor beta 2 inhibits cerebrovascular changes and brain edema formation in the tumor necrosis factor alpha-independent early phase of experimental pneumococcal meningitis. The Journal of experimental medicine. 1992 Academic Article GET IT
Times cited: 61
Peptidoglycan composition in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain. The Journal of biological chemistry. 1992 Academic Article GET IT
Times cited: 81
Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A. The Journal of biological chemistry. 1992 Academic Article GET IT
Times cited: 263
A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone. Antimicrobial agents and chemotherapy. 1992 Academic Article GET IT
Times cited: 92
Multiple methicillin-resistant Staphylococcus aureus strains as a cause for a single outbreak of severe disease in hospitalized neonates. The Pediatric infectious disease journal. 1992 Academic Article GET IT
Times cited: 38
In vivo stability of heterogeneous expression classes in clinical isolates of methicillin-resistant staphylococci. The Journal of infectious diseases. 1991 Academic Article GET IT
Times cited: 36
Multiple mechanisms of methicillin resistance and improved methods for detection in clinical isolates of Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1991 Academic Article GET IT
Times cited: 156
Extremely high incidence of antibiotic resistance in clinical isolates of Streptococcus pneumoniae in Hungary. The Journal of infectious diseases. 1991 Academic Article GET IT
Times cited: 262
Suppression of autolysis and cell wall turnover in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain. Journal of bacteriology. 1991 Academic Article GET IT
Times cited: 42
Stable classes of phenotypic expression in methicillin-resistant clinical isolates of staphylococci. Antimicrobial agents and chemotherapy. 1991 Academic Article GET IT
Times cited: 234
Changes in composition of peptidoglycan during maturation of the cell wall in pneumococci. Journal of bacteriology. 1990 Academic Article GET IT
Times cited: 10
Insertional inactivation of the mec gene in a transposon mutant of a methicillin-resistant clinical isolate of Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1990 Academic Article GET IT
Times cited: 49
A biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin-resistant pneumococci. Proceedings of the National Academy of Sciences of the United States of America. 1990 Academic Article GET IT
Times cited: 126
Protein-bound choline is released from the pneumococcal autolytic enzyme during adsorption of the enzyme to cell wall particles. Journal of bacteriology. 1990 Academic Article GET IT
Times cited: 7
Mechanism of phenotypic tolerance of nongrowing pneumococci to beta-lactam antibiotics. Scandinavian journal of infectious diseases. Supplementum. 1990 Academic Article GET IT
Times cited: 38
Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanisms. Antimicrobial agents and chemotherapy. 1990 Academic Article GET IT
Times cited: 83
The nature of cell wall-derived inflammatory components of pneumococci. The Pediatric infectious disease journal. 1989 Academic Article GET IT
Times cited: 38
Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae. Proceedings of the National Academy of Sciences of the United States of America. 1989 Academic Article GET IT
Times cited: 319
New mechanism for methicillin resistance in Staphylococcus aureus: clinical isolates that lack the PBP 2a gene and contain normal penicillin-binding proteins with modified penicillin-binding capacity. Antimicrobial agents and chemotherapy. 1989 Academic Article GET IT
Times cited: 232
Lytic and bactericidal activity of FCE 22101. The Journal of antimicrobial chemotherapy. 1989 Academic Article GET IT
Times cited: 6
Variation in penicillin-binding protein patterns of penicillin-resistant clinical isolates of pneumococci. Journal of clinical microbiology. 1989 Academic Article GET IT
Times cited: 85
DNA probe for identification of Streptococcus pneumoniae. Journal of clinical microbiology. 1989 Academic Article GET IT
Times cited: 31
Involvement of multiple genetic determinants in high-level methicillin resistance in Staphylococcus aureus. Journal of bacteriology. 1989 Academic Article GET IT
Times cited: 117
Mechanism of pneumococcal cell wall degradation in vitro and in vivo. Journal of bacteriology. 1989 Academic Article GET IT
Times cited: 9
Penicillin-binding protein families: evidence for the clonal nature of penicillin resistance in clinical isolates of pneumococci. The Journal of infectious diseases. 1989 Academic Article GET IT
Times cited: 84
Insertional inactivation of the major autolysin gene of Streptococcus pneumoniae. Journal of bacteriology. 1988 Academic Article GET IT
Times cited: 69
Penicillin resistance and defective lysis in clinical isolates of pneumococci: evidence for two kinds of antibiotic pressure operating in the clinical environment. The Journal of infectious diseases. 1988 Academic Article GET IT
Times cited: 64
Altered peptidoglycan structure in a pneumococcal transformant resistant to penicillin. Journal of bacteriology. 1988 Academic Article GET IT
Times cited: 53
A sandwich adhesion on Streptococcus pneumoniae attaching to human oropharyngeal epithelial cells in vitro. Microbial pathogenesis. 1988 Academic Article GET IT
Times cited: 25
Autolysis-resistant peptidoglycan of anomalous composition in amino-acid-starved Escherichia coli. Journal of bacteriology. 1988 Academic Article GET IT
Times cited: 30
The contribution of pneumococcal cell wall to the pathogenesis of experimental otitis media. The Journal of infectious diseases. 1988 Academic Article GET IT
Times cited: 47
Contribution of pneumococcal cell wall to experimental otitis media pathogenesis. The Annals of otology, rhinology & laryngology. Supplement. 1988 Academic Article GET IT
Times cited: 4
Structure of the peptide network of pneumococcal peptidoglycan. The Journal of biological chemistry. 1987 Academic Article GET IT
Times cited: 91
A mutant of Streptococcus pneumoniae that exhibits thermosensitive penicillin tolerance and the paradoxical effect. Journal of general microbiology. 1987 Academic Article GET IT
Times cited: 4
Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis. The Journal of infectious diseases. 1987 Academic Article GET IT
Times cited: 130
Teichoic acid-containing muropeptides from Streptococcus pneumoniae as substrates for the pneumococcal autolysin. Journal of bacteriology. 1987 Academic Article GET IT
Times cited: 52
Construction of a penicillin-tolerant laboratory mutant of Staphylococcus aureus. European journal of clinical microbiology. 1986 Academic Article GET IT
Times cited: 14
Conversion of a homogeneously methicillin-resistant strain of Staphylococcus aureus to heterogeneous resistance by Tn551-mediated insertional inactivation. European journal of clinical microbiology. 1986 Academic Article GET IT
Times cited: 76
Induction of meningeal inflammation by diverse bacterial cell walls. European journal of clinical microbiology. 1986 Academic Article GET IT
Times cited: 31
Modulation of bacteriolysis by cooperative effects of penicillin-binding proteins 1a and 3 in Escherichia coli. Antimicrobial agents and chemotherapy. 1986 Academic Article GET IT
Times cited: 37
Antibiotic tolerance among clinical isolates of bacteria. Antimicrobial agents and chemotherapy. 1986 Review GET IT
Times cited: 175
Beta-lactam-specific resistant mutants of Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1986 Academic Article GET IT
Times cited: 39
Penicillin-binding proteins of penicillin-susceptible and -resistant pneumococci: immunological relatedness of altered proteins and changes in peptides carrying the beta-lactam binding site. Antimicrobial agents and chemotherapy. 1986 Academic Article GET IT
Times cited: 69
Induction of autolysis in nongrowing Escherichia coli. Journal of bacteriology. 1986 Academic Article GET IT
Times cited: 26
Transglycosylase and endopeptidase participate in the degradation of murein during autolysis of Escherichia coli. Journal of bacteriology. 1986 Academic Article GET IT
Times cited: 33
Alterations in kinetic properties of penicillin-binding proteins of penicillin-resistant Streptococcus pneumoniae. Antimicrobial agents and chemotherapy. 1986 Academic Article GET IT
Times cited: 28
Evaluation of the bactericidal activity of beta-lactam antibiotics on slowly growing bacteria cultured in the chemostat. Antimicrobial agents and chemotherapy. 1986 Academic Article GET IT
Times cited: 131
Mutants of Streptococcus pneumoniae that contain a temperature-sensitive autolysin. Journal of general microbiology. 1986 Academic Article GET IT
Times cited: 7
The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth. Journal of general microbiology. 1986 Academic Article GET IT
Times cited: 380
The role of complement in inflammation during experimental pneumococcal meningitis. Microbial pathogenesis. 1986 Academic Article GET IT
Times cited: 50
Alterations in penicillin-binding proteins of clinical and laboratory isolates of pathogenic Streptococcus pneumoniae with low levels of penicillin resistance. The Journal of infectious diseases. 1986 Academic Article GET IT
Times cited: 45
Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1986 Academic Article GET IT
Times cited: 201
Penicillin-binding proteins and the antibacterial effectiveness of beta-lactam antibiotics. Reviews of infectious diseases. 1986 Review GET IT
Times cited: 91
Inhibition of cell wall synthesis and acylation of the penicillin binding proteins during prolonged exposure of growing Streptococcus pneumoniae to benzylpenicillin. European journal of biochemistry. 1985 Academic Article GET IT
Times cited: 31
Penicillin tolerance in multiply drug-resistant natural isolates of Streptococcus pneumoniae. The Journal of infectious diseases. 1985 Academic Article GET IT
Times cited: 78
Increased amounts of a novel penicillin-binding protein in a strain of methicillin-resistant Staphylococcus aureus exposed to nafcillin. The Journal of clinical investigation. 1985 Academic Article GET IT
Times cited: 69
Peptidoglycan cross-linking and teichoic acid attachment in Streptococcus pneumoniae. Journal of bacteriology. 1985 Academic Article GET IT
Times cited: 28
Factors affecting sensitivity of group B streptococci to an exogenous murein hydrolase. Canadian journal of microbiology. 1985 Academic Article GET IT
Times cited: 1
Response of Legionella pneumophila to beta-lactam antibiotics. Antimicrobial agents and chemotherapy. 1985 Academic Article GET IT
Times cited: 3
The induction of meningeal inflammation by components of the pneumococcal cell wall. The Journal of infectious diseases. 1985 Academic Article GET IT
Times cited: 287
Competence-specific autolysis in Streptococcus sanguis. Journal of general microbiology. 1985 Academic Article GET IT
Times cited: 5
The relative role of bacterial cell wall and capsule in the induction of inflammation in pneumococcal meningitis. The Journal of infectious diseases. 1985 Academic Article GET IT
Times cited: 188
Activation of the alternative complement pathway by pneumococcal lipoteichoic acid. Infection and immunity. 1985 Academic Article GET IT
Times cited: 44
Antibiotic tolerance among clinical isolates of bacteria. Annual review of pharmacology and toxicology. 1985 Review GET IT
Times cited: 43
Antibiotic tolerance among clinical isolates of bacteria. Reviews of infectious diseases. 1985 Review GET IT
Times cited: 161
Pneumococcal Forssman antigen: enrichment in mesosomal membranes and specific binding to the autolytic enzyme of Streptococcus pneumoniae. Journal of bacteriology. 1985 Academic Article GET IT
Times cited: 14
Protection by D-amino acids against growth inhibition and lysis caused by beta-lactam antibiotics. Antimicrobial agents and chemotherapy. 1984 Academic Article GET IT
Times cited: 6
Attachment of pneumococcal autolysin to wall teichoic acids, an essential step in enzymatic wall degradation. Journal of bacteriology. 1984 Academic Article GET IT
Times cited: 81
Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus. Journal of bacteriology. 1984 Academic Article GET IT
Times cited: 632
Production and release of peptidoglycan and wall teichoic acid polymers in pneumococci treated with beta-lactam antibiotics. Journal of bacteriology. 1984 Academic Article GET IT
Times cited: 45
Effect of penicillin on the adherence of Streptococcus sanguis in vitro and in the rabbit model of endocarditis. The Journal of clinical investigation. 1983 Academic Article GET IT
Times cited: 27
Studies on the mechanism of intrinsic resistance to beta-lactam antibiotics in group D streptococci. Journal of general microbiology. 1983 Academic Article GET IT
Times cited: 60
A phage-associated murein hydrolase in Streptococcus pneumoniae infected with bacteriophage Dp-1. Journal of general microbiology. 1983 Academic Article GET IT
Times cited: 15
Mechanism of phage-induced lysis in pneumococci. Journal of general microbiology. 1983 Academic Article GET IT
Times cited: 14
Choline-containing bacteriophage receptors in Streptococcus pneumoniae. Journal of bacteriology. 1982 Academic Article GET IT
Times cited: 30
Penicillin-resistant and penicillin-tolerant mutants of group A Streptococci. Antimicrobial agents and chemotherapy. 1982 Academic Article GET IT
Times cited: 42
Staphylococcal plasmids that replicate and express erythromycin resistance in both Streptococcus pneumoniae and Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 1982 Academic Article GET IT
Times cited: 21
Penicillin-binding proteins in bacteria. Annals of internal medicine. 1982 Review GET IT
Times cited: 22
The fixation of C3b to pneumococcal cell wall polymers as a result of activation of the alternative complement pathway. Journal of immunology (Baltimore, Md. : 1950). 1981 Academic Article GET IT
Times cited: 15
Competition of beta-lactam antibiotics for the penicillin-binding proteins of Neisseria gonorrhoeae. Antimicrobial agents and chemotherapy. 1981 Academic Article GET IT
Times cited: 24
pH-dependent penicillin tolerance of group B streptococci. Antimicrobial agents and chemotherapy. 1981 Academic Article GET IT
Times cited: 16
Altered penicillin-binding proteins in methicillin-resistant strains of Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1981 Academic Article GET IT
Times cited: 122
Hypersusceptibility of penicillin-treated group B streptococci to bactericidal activity of human polymorphonuclear leukocytes. Antimicrobial agents and chemotherapy. 1981 Academic Article GET IT
Times cited: 33
Physiological properties of penicillin-binding proteins in group A streptococci. Antimicrobial agents and chemotherapy. 1981 Academic Article GET IT
Times cited: 20
Multiple antibiotic resistance in South African strains of Streptococcus pneumoniae: mechanism of resistance to beta-lactam antibiotics. Reviews of infectious diseases. 1981 Academic Article GET IT
Times cited: 37
Surface components of Streptococcus pneumoniae. Reviews of infectious diseases. 1981 Academic Article GET IT
Times cited: 52
Alteration of Escherichia coli murein during amino acid starvation. Journal of bacteriology. 1980 Academic Article GET IT
Times cited: 33
Genetic transformation of Streptococcus pneumoniae by heterologous plasmid deoxyribonucleic acid. Journal of bacteriology. 1980 Academic Article GET IT
Times cited: 30
Penicillin-binding proteins of penicillin-susceptible and intrinsically resistant Neisseria gonorrhoeae. Antimicrobial agents and chemotherapy. 1980 Academic Article GET IT
Times cited: 81
Antibiotic-tolerant mutants of Streptococcus pneumoniae that are not deficient in autolytic activity. Journal of bacteriology. 1980 Academic Article GET IT
Times cited: 28
In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy. 1980 Academic Article GET IT
Times cited: 73
Activation of C3 via the alternative complement pathway results in fixation of C3b to the pneumococcal cell wall. Journal of immunology (Baltimore, Md. : 1950). 1980 Academic Article GET IT
Times cited: 39
Multiple changes of penicillin-binding proteins in penicillin-resistant clinical isolates of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy. 1980 Academic Article GET IT
Times cited: 161
Penicillin-binding proteins of multiply antibiotic-resistant South African strains of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy. 1980 Academic Article GET IT
Times cited: 174
Lethal effect of a heterologous murein hydrolase on penicillin-treated Streptococcus sanguis. Antimicrobial agents and chemotherapy. 1980 Academic Article GET IT
Times cited: 15
Escherichia coli mutants tolerant to beta-lactam antibiotics. Journal of bacteriology. 1979 Academic Article GET IT
Times cited: 18
Triggering of autolytic cell wall degradation in Escherichia coli by beta-lactam antibiotics. Antimicrobial agents and chemotherapy. 1979 Academic Article GET IT
Times cited: 63
Release of lipoteichoic acid from Streptococcus sanguis: stimulation of release during penicillin treatment. Journal of bacteriology. 1979 Academic Article GET IT
Times cited: 29
Specificity of DNA uptake in genetic transformation of gonococci. Biochemical and biophysical research communications. 1979 Academic Article GET IT
Times cited: 39
From penicillin-binding proteins to the lysis and death of bacteria: a 1979 view. Reviews of infectious diseases. 1979 Review GET IT
Times cited: 93
The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria. Annual review of microbiology. 1979 Review GET IT
Times cited: 267
Induction of normal levels of genetic transformation in a class of endonuclease-defective mutants of Pneumococci. Biochemical and biophysical research communications. 1978 Academic Article GET IT
Times cited: 3
Transfection of Streptococcus pneumoniae with bacteriophage DNA. Journal of virology. 1978 Academic Article GET IT
Times cited: 9
Effect of benzylpenicillin on the synthesis and structure of the cell envelope of Neisseria gonorrhoeae. Antimicrobial agents and chemotherapy. 1978 Academic Article GET IT
Times cited: 22
Characterization of cell wall polymers secreted into the growth medium of lysis-defective pneumococci during treatment with penicillin and other inhibitors of cell wall synthesis. Antimicrobial agents and chemotherapy. 1978 Academic Article GET IT
Times cited: 12
Secretion of cell wall polymers into the growth medium of lysis-defective pneumococci during treatment with penicillin and other inhibitors of cell wall synthesis. Antimicrobial agents and chemotherapy. 1978 Academic Article GET IT
Times cited: 14
Activation of the alternative complement pathway by pneumococcal cell wall teichoic acid. Journal of immunology (Baltimore, Md. : 1950). 1978 Academic Article GET IT
Times cited: 78
Secretion of lipids induced by inhibition of peptidoglycan synthesis in streptococci. Journal of bacteriology. 1977 Academic Article GET IT
Times cited: 32
Properties of "diplophage": a lipid-containing bacteriophage. Journal of virology. 1977 Academic Article GET IT
Times cited: 17
The activity of the pneumococcal autolytic system and the fate of the bacterium during ingestion by rabbit polymorphonuclear leukocytes. Journal of cellular physiology. 1977 Academic Article GET IT
Times cited: 10
Tolerant response of Streptococcus sanguis to beta-lactams and other cell wall inhibitors. Antimicrobial agents and chemotherapy. 1977 Academic Article GET IT
Times cited: 51
Choline metabolism in pneumococci. Journal of bacteriology. 1977 Academic Article GET IT
Times cited: 15
Activation of the alternative pathway by pneumococcal cell walls. Journal of immunology (Baltimore, Md. : 1950). 1977 Academic Article GET IT
Times cited: 35
Inhibitors of genetic recombination in pneumococci. Proceedings of the National Academy of Sciences of the United States of America. 1977 Academic Article GET IT
Times cited: 14
Role of the pneumococcal autolysin (murein hydrolase) in the release of progeny bacteriophage and in the bacteriophage-induced lysis of the host cells. Journal of virology. 1977 Academic Article GET IT
Times cited: 22
Suppression of the lytic and bactericidal effects of cell wallinhibitory antibiotics. Antimicrobial agents and chemotherapy. 1976 Academic Article GET IT
Times cited: 19
Suppression of lytic effect of beta lactams on Escherichia coli and other bacteria. Proceedings of the National Academy of Sciences of the United States of America. 1976 Academic Article GET IT
Times cited: 35
Purification of the pneumococcal N-acetylmuramyl-L-alanine amidase to biochemical homogeneity. The Journal of biological chemistry. 1976 Academic Article GET IT
Times cited: 86
Calcium-requiring step in the uptake of deoxyribonucleic acid molecules through the surface of competent pneumococci. Journal of bacteriology. 1976 Academic Article GET IT
Times cited: 13
Inhibition of bacterial wall lysins by lipoteichoic acids and related compounds. Biochemical and biophysical research communications. 1975 Academic Article GET IT
Times cited: 69
Biological effects of lipoteichoic acids. Journal of bacteriology. 1975 Academic Article GET IT
Times cited: 20
Selective release of a deoxyribonucleic acid-binding factor from the surface of competent pneumococci. Journal of bacteriology. 1975 Academic Article GET IT
Times cited: 11
Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis. Proceedings of the National Academy of Sciences of the United States of America. 1975 Academic Article GET IT
Times cited: 145
Enzyme replacement in a bacterium: phenotypic correction by the experimental introduction of the wild type enzyme into a live enzyme defective mutant pneumococcus. Biochemical and biophysical research communications. 1975 Academic Article GET IT
Times cited: 14
Specific recognition of choline residues in the cell wall teichoic acid by the N-acetylmuramyl-L-alanine amidase of Pneumococcus. The Journal of biological chemistry. 1975 Academic Article GET IT
Times cited: 92
Cell surface-located deoxyribonucleic acid receptors in transformable pneumococci. Journal of bacteriology. 1975 Academic Article GET IT
Times cited: 19
Lipoteichoic acid: a specific inhibitor of autolysin activity in Pneumococcus. Proceedings of the National Academy of Sciences of the United States of America. 1975 Academic Article GET IT
Times cited: 136
Nucleolytic degradation of homologous and heterologous deoxyribonucleic acid molecules at the surface of competent pneumococci. Journal of bacteriology. 1975 Academic Article GET IT
Times cited: 8
Membrane lipoteichoic acid is not a precursor to wall teichoic acid in pneumococci. Journal of bacteriology. 1975 Academic Article GET IT
Times cited: 11
"Diplophage": a bacteriophage of Diplococcus pneumoniae. Virology. 1975 Academic Article GET IT
Times cited: 37
Physiological studies on the pneumococcal Forssman antigen: a choline-containing lipoteichoic acid. Journal of general microbiology. 1975 Academic Article GET IT
Times cited: 2
Coordinated incorporation of nascent peptidoglycan and teichoic acid into pneumococcal cell walls and conservation of peptidoglycan during growth. The Journal of biological chemistry. 1975 Academic Article GET IT
Times cited: 19
On the physiological functions of teichoic acids. Journal of supramolecular structure. 1975 Academic Article GET IT
Times cited: 31
Protoplast formation and leakage of intramembrane cell components: induction by the competence activator substance of pneumococci. Journal of bacteriology. 1975 Academic Article GET IT
Times cited: 26
Teichoic acid phosphorylcholine esterase. A novel enzyme activity in pneumococcus. The Journal of biological chemistry. 1974 Academic Article GET IT
Times cited: 26
The role of autolysins in cell death. Annals of the New York Academy of Sciences. 1974 Academic Article GET IT
Times cited: 37
Early stages in DNA binding and uptake during genetic transformation of pneumococci. Proceedings of the National Academy of Sciences of the United States of America. 1974 Academic Article GET IT
Times cited: 22
Pneumococcal Forssman antigen. A choline-containing lipoteichoic acid. The Journal of biological chemistry. 1973 Academic Article GET IT
Times cited: 64
5-Fluoropyrimidine-resistant mutants of pneumococcus. Journal of bacteriology. 1973 Academic Article GET IT
Times cited: 2
Selective utilization of pyrimidine deoxyribonucleosides for deoxyribonucleic acid synthesis in pneumococcus. Journal of bacteriology. 1973 Academic Article GET IT
Times cited: 1
The bacterial cell surface. Nature. 1971 Academic Article GET IT
Times cited: 4
Abnormal autolytic enzyme in a pneumococus with altered teichoic acid composition. Proceedings of the National Academy of Sciences of the United States of America. 1971 Academic Article GET IT
Times cited: 63
DNA uptake during genetic transformation and the growing zone of the cell envelope. Proceedings of the National Academy of Sciences of the United States of America. 1971 Academic Article GET IT
Times cited: 29
Inhibitory effects and metabolism of 5-fluoropyrimidine derivatives in pneumococcus. Journal of bacteriology. 1971 Academic Article GET IT
Times cited: 6
ppearance of a protein "agglutinin" on the spheroplast membrane of pneumococci during induction of competence. Journal of bacteriology. 1971 Academic Article GET IT
Times cited: 18
Binding of the competence factor to receptors in the spheroplast membrane of pneumococci. Biochemical and biophysical research communications. 1970 Academic Article GET IT
Times cited: 11
Radioautographic evidence for equatorial wall growth in a gram-positive bacterium. Segregation of choline-3H-labeled teichoic acid. The Journal of cell biology. 1970 Academic Article GET IT
Times cited: 34
Multiple antibiotic resistance in a bacterium with suppressed autolytic system. Nature. 1970 Academic Article GET IT
Times cited: 279
Cellular metabolism in genetic transformation of pneumococci: requirement for protein synthesis during induction of competence. Journal of bacteriology. 1970 Academic Article GET IT
Times cited: 58
Choline-containing teichoic acid as a structural component of pneumococcal cell wall and its role in sensitivity to lysis by an autolytic enzyme. The Journal of biological chemistry. 1970 Academic Article GET IT
Times cited: 198
Cellular factors in genetic transformation. Scientific American. 1969 Academic Article GET IT
Times cited: 1
An autoradiographic study of genetic transformation. Proceedings of the National Academy of Sciences of the United States of America. 1968 Academic Article GET IT
Times cited: 13
Choline in the cell wall of a bacterium: novel type of polymer-linked choline in Pneumococcus. Science (New York, N.Y.). 1967 Academic Article GET IT
Times cited: 166
Model for the mechanism controlling the expression of competent state in Pneumococcus cultures. Journal of bacteriology. 1966 Academic Article GET IT
Times cited: 55
On the nature of the pneumococcal activator substance. Proceedings of the National Academy of Sciences of the United States of America. 1966 Academic Article GET IT
Times cited: 78
Relationship between the competence antigen and the competence-activator substance in pneumococci. Journal of bacteriology. 1965 Academic Article GET IT
Times cited: 10
Control of the competent state in Pneumococcus by a hormone-like cell product: an example for a new type of regulatory mechanism in bacteria. Nature. 1965 Academic Article GET IT
Times cited: 156
The mechanism of an osmotic instability induced in E. coli K-12 by 5-fluorouracil. Biochemistry. 1962 Academic Article GET IT
Times cited: 16
THE MECHANISM OF BACTERIAL FRAGILITY PRODUCED BY 5-FLUOROURACIL: THE ACCUMULATION OF CELL WALL PRECURSORS. Proceedings of the National Academy of Sciences of the United States of America. 1960 Academic Article GET IT
AN EARLY PHASE IN THE BACTERICIDAL ACTION OF 5-FLUOROURACIL ON E. COLI K(12). OSMOTIC IMBALANCE. Proceedings of the National Academy of Sciences of the United States of America. 1959 Academic Article GET IT

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Background

education and training

Ph.D., Columbia University 1961
B.S., Eotvos University (Hungary) 1953

Contact

full name

Alexander Tomasz

VIVO Weill Cornell Medical College

Alexander Tomasz Adjunct Professor of Microbiology in Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name