selected publications
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Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non‒Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis.
The Journal of investigative dermatology.
2022
Academic Article
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Times cited: 2 -
Analysis of alopecia areata surveys suggests a threshold for improved patient-reported outcomes.
The British journal of dermatology.
2022
Academic Article
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Times cited: 4 -
Interleukin-17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum.
The British journal of dermatology.
2022
Academic Article
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Times cited: 12 - Raising the bar for efficacy in hidradenitis suppurativa: a rationale for combination targeted therapies. The British journal of dermatology. 2022 Letter GET IT
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Ustekinumab reduces serum protein levels associated with cardiovascular risk in psoriasis vulgaris.
Experimental dermatology.
2022
Academic Article
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Times cited: 1 -
Secukinumab improves mild-to-moderate psoriasis: A randomized, placebo-controlled exploratory clinical trial.
Journal of the American Academy of Dermatology.
2022
Academic Article
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Times cited: 1 -
Transcriptomic Analysis of the Major Orphan Ichthyosis Subtypes Reveals Shared Immune and Barrier Signatures.
The Journal of investigative dermatology.
2022
Academic Article
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Times cited: 6 -
Treatment Options and Goals for Patients with Generalized Pustular Psoriasis.
American journal of clinical dermatology.
2022
Review
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Times cited: 21 -
Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa, randomized, double-blind multicentre study.
The British journal of dermatology.
2021
Academic Article
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Times cited: 7 -
A Randomized Open-Label Clinical Trial of Lipid-Lowering Therapy in Psoriasis to Reduce Vascular Endothelial Inflammation.
The Journal of investigative dermatology.
2021
Academic Article
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Times cited: 8 -
Molecular and clinical effects of selective tyrosine kinase 2 inhibition with deucravacitinib in psoriasis.
The Journal of allergy and clinical immunology.
2021
Academic Article
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Times cited: 18 -
Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial.
JAMA dermatology.
2021
Academic Article
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Times cited: 6 -
Large-scale serum analysis identifies unique systemic biomarkers in psoriasis and hidradenitis suppurativa.
The British journal of dermatology.
2021
Academic Article
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Times cited: 4 -
Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis.
The Journal of allergy and clinical immunology.
2021
Academic Article
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Times cited: 19 - Response to 'Lack of efficacy of dupilumab in the treatment of keloid disorder' by MH Tirgan and J Uitto. Journal of the European Academy of Dermatology and Venereology : JEADV. 2021 Letter GET IT
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Transcriptomic Profiling of Tape-Strips From Moderate to Severe Atopic Dermatitis Patients Treated With Dupilumab.
Dermatitis : contact, atopic, occupational, drug.
2021
Academic Article
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Times cited: 7 -
Phase 2a randomized clinical trial of dupilumab (anti-IL-4Rα) for alopecia areata patients.
Allergy.
2021
Academic Article
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Times cited: 30 -
TH 2 cytokines and Staphylococcus aureus cooperatively induce atopic dermatitis-like transcriptomes.
Allergy.
2021
Letter
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Times cited: 4 -
Assessing the responsiveness of sonographic biomarkers to Brodalumab therapy in Hidradenitis Suppurativa.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2021
Letter
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Times cited: 1 -
The Rockefeller Team Science Leadership training program: Curriculum, standardized assessment of competencies, and impact of returning assessments.
Journal of clinical and translational science.
2021
Academic Article
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Times cited: 2 -
The inflammatory proteome of hidradenitis suppurativa skin is more expansive than that of psoriasis vulgaris.
Journal of the American Academy of Dermatology.
2021
Academic Article
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Times cited: 9 -
Capsaicin attenuates imiquimod-induced epidermal hyperplasia and cutaneous inflammation in a murine model of psoriasis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021
Academic Article
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Times cited: 6 -
Tyrosine kinase 2 and Janus kinase‒signal transducer and activator of transcription signaling and inhibition in plaque psoriasis.
Journal of the American Academy of Dermatology.
2021
Review
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Times cited: 22 - The Busy Arena of Psoriasis Treatments: Improving the Clinician's Ability to Make the Right Therapeutic Choice. American journal of clinical dermatology. 2021 Letter GET IT
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The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa.
Frontiers in medicine.
2021
Academic Article
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Times cited: 27 -
An integrated scalp and blood biomarker approach suggests the systemic nature of alopecia areata.
Allergy.
2021
Academic Article
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Times cited: 10 -
High inflammation in hidradenitis suppurativa extends to perilesional skin and can be subdivided by lipocalin-2 expression.
The Journal of allergy and clinical immunology.
2021
Academic Article
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Times cited: 4 -
Signalling of multiple interleukin (IL)-17 family cytokines via IL-17 receptor A drives psoriasis-related inflammatory pathways.
The British journal of dermatology.
2021
Academic Article
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Times cited: 18 -
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement.
Journal of the American Academy of Dermatology.
2021
Academic Article
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Times cited: 4 -
Immune and barrier characterization of atopic dermatitis skin phenotype in Tanzanian patients.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2021
Academic Article
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Times cited: 12 -
Deep learning automated pathology in ex vivo microscopy.
Biomedical optics express.
2021
Academic Article
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Times cited: 13 -
Vascular inflammation in moderate-to-severe atopic dermatitis is associated with enhanced Th2 response.
Allergy.
2021
Academic Article
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Times cited: 16 -
Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic versus regulatory immune cell subsets.
The Journal of allergy and clinical immunology.
2021
Academic Article
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Times cited: 26 -
High-dimensional analysis defines multicytokine T-cell subsets and supports a role for IL-21 in atopic dermatitis.
Allergy.
2021
Academic Article
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Times cited: 4 -
Cardiovascular Risk in Patients With Psoriasis: JACC Review Topic of the Week.
Journal of the American College of Cardiology.
2021
Review
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Times cited: 34 - Author Correction: Obesity and ethnicity alter gene expression in skin. Scientific reports. 2021 Article GET IT
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In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes.
The Journal of investigative dermatology.
2021
Academic Article
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Times cited: 19 -
IL-36 and IL-17A Cooperatively Induce a Psoriasis-Like Gene Expression Response in Human Keratinocytes.
The Journal of investigative dermatology.
2021
Letter
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Times cited: 6 -
Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial.
Lancet (London, England).
2021
Academic Article
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Times cited: 76 -
Epithelialized tunnels are a source of inflammation in hidradenitis suppurativa.
The Journal of allergy and clinical immunology.
2021
Academic Article
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Times cited: 32 -
The molecular features of normal and atopic dermatitis skin in infants, children, adolescents, and adults.
The Journal of allergy and clinical immunology.
2021
Academic Article
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Times cited: 40 -
The erythema Q-score, an imaging biomarker for redness in skin inflammation.
Experimental dermatology.
2020
Academic Article
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Times cited: 4 -
CCL20 in psoriasis: A potential biomarker of disease severity, inflammation, and impaired vascular health.
Journal of the American Academy of Dermatology.
2020
Academic Article
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Times cited: 18 -
International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale.
BMJ open.
2020
Academic Article
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Times cited: 6 -
RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing.
Frontiers in immunology.
2020
Academic Article
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Times cited: 31 -
Quantifying the natural variation in lesion counts over time in untreated hidradenitis suppurativa: Implications for outcome measures and trial design.
JAAD international.
2020
Academic Article
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Times cited: 4 -
Deep learning-level melanoma detection by interpretable machine learning and imaging biomarker cues.
Journal of biomedical optics.
2020
Academic Article
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Times cited: 8 -
Dermal tunnels influence time to clinical response and family history influences time to loss of clinical response in patients with hidradenitis suppurativa treated with adalimumab.
Clinical and experimental dermatology.
2020
Academic Article
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Times cited: 11 -
Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities.
The Journal of allergy and clinical immunology.
2020
Academic Article
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Times cited: 39 -
Secukinumab lowers expression of ACE2 in affected skin of patients with psoriasis.
The Journal of allergy and clinical immunology.
2020
Letter
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Times cited: 12 -
Weekly administration of brodalumab in hidradenitis suppurativa: an open-label cohort study.
The British journal of dermatology.
2020
Letter
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Times cited: 13 -
A phase I, randomized, double-blind study to assess the safety, tolerability and efficacy of the topical RORC2 inverse agonist PF-06763809 in participants with mild-to-moderate plaque psoriasis.
Clinical and experimental dermatology.
2020
Academic Article
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Times cited: 6 -
Doppler ultrasound-based noninvasive biomarkers in hidradenitis suppurativa: evaluation of analytical and clinical validity.
The British journal of dermatology.
2020
Academic Article
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Times cited: 15 -
Tape-strips provide a minimally invasive approach to track therapeutic response to topical corticosteroids in atopic dermatitis patients.
The journal of allergy and clinical immunology. In practice.
2020
Academic Article
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Times cited: 11 -
SARS-CoV-2 receptor ACE2 protein expression in serum is significantly associated with age.
Allergy.
2020
Letter
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Times cited: 21 -
Obesity and ethnicity alter gene expression in skin.
Scientific reports.
2020
Academic Article
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Times cited: 6 -
Tape strips from early-onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin.
Allergy.
2020
Academic Article
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Times cited: 44 -
A systematic review and critical appraisal of metagenomic and culture studies in hidradenitis suppurativa.
Experimental dermatology.
2020
Academic Article
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Times cited: 13 -
A Preliminary 18F-FDG-PET/MRI Study Shows Increased Vascular Inflammation in Moderate-to-Severe Atopic Dermatitis.
The journal of allergy and clinical immunology. In practice.
2020
Academic Article
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Times cited: 9 -
Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis.
The Journal of allergy and clinical immunology.
2020
Academic Article
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Times cited: 77 -
Improving evaluation of drugs in atopic dermatitis by combining clinical and molecular measures.
The journal of allergy and clinical immunology. In practice.
2020
Academic Article
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Times cited: 11 -
A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue.
Oncotarget.
2020
Academic Article
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Times cited: 11 -
Response to Inhibition of Receptor-Interacting Protein Kinase 1 (RIPK1) in Active Plaque Psoriasis: A Randomized Placebo-Controlled Study.
Clinical pharmacology and therapeutics.
2020
Academic Article
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Times cited: 33 -
Characterization of PCSK9 in the Blood and Skin of Psoriasis.
The Journal of investigative dermatology.
2020
Academic Article
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Times cited: 14 -
Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing.
The British journal of dermatology.
2020
Academic Article
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Times cited: 23 -
Malignancy and infection risk during adalimumab therapy in hidradenitis suppurativa.
Clinical and experimental dermatology.
2020
Academic Article
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Times cited: 6 -
The effect of subcutaneous brodalumab on clinical disease activity in hidradenitis suppurativa: An open-label cohort study.
Journal of the American Academy of Dermatology.
2020
Academic Article
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Times cited: 43 -
NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices.
Nature cell biology.
2020
Academic Article
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Times cited: 33 -
Cross-sectional study of blood biomarkers of patients with moderate to severe alopecia areata reveals systemic immune and cardiovascular biomarker dysregulation.
Journal of the American Academy of Dermatology.
2020
Academic Article
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Times cited: 25 -
Beyond antibodies: B cells in Hidradenitis Suppurativa: Bystanders, contributors or therapeutic targets?.
Experimental dermatology.
2020
Academic Article
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Times cited: 11 -
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1.
Arteriosclerosis, thrombosis, and vascular biology.
2020
Academic Article
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Times cited: 37 -
The aging skin microenvironment dictates stem cell behavior.
Proceedings of the National Academy of Sciences of the United States of America.
2020
Academic Article
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Times cited: 61 -
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis.
The Journal of allergy and clinical immunology.
2020
Academic Article
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Times cited: 156 -
Defining drug-free remission of skin disease in patients with plaque psoriasis.
The British journal of dermatology.
2020
Letter
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Times cited: 2 -
Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis.
The Journal of investigative dermatology.
2020
Academic Article
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Times cited: 33 -
Comparing cutaneous molecular improvement with different treatments in atopic dermatitis patients.
The Journal of allergy and clinical immunology.
2020
Letter
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Times cited: 14 -
Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis.
The Journal of allergy and clinical immunology.
2019
Academic Article
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Times cited: 30 -
Clinical response rates, placebo response rates, and significantly associated covariates are dependent on choice of outcome measure in hidradenitis suppurativa: A post hoc analysis of PIONEER 1 and 2 individual patient data.
Journal of the American Academy of Dermatology.
2019
Academic Article
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Times cited: 35 -
Keloid lesions show increased IL-4/IL-13 signaling and respond to Th2-targeting dupilumab therapy.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2019
Letter
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Times cited: 35 -
Interleukin 17C is elevated in lesional tissue of hidradenitis suppurativa.
The British journal of dermatology.
2019
Letter
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Times cited: 19 -
Use of Tape Strips to Detect Immune and Barrier Abnormalities in the Skin of Children With Early-Onset Atopic Dermatitis.
JAMA dermatology.
2019
Academic Article
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Times cited: 85 -
Persistence of Inflammatory Phenotype in Residual Psoriatic Plaques in Patients on Effective Biologic Therapy.
The Journal of investigative dermatology.
2019
Academic Article
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Times cited: 11 -
Early Quantification of Systemic Inflammatory Proteins Predicts Long-Term Treatment Response to Tofacitinib and Etanercept.
The Journal of investigative dermatology.
2019
Academic Article
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Times cited: 14 -
The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature.
Journal of the American Academy of Dermatology.
2019
Academic Article
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Times cited: 66 -
Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood.
The Journal of allergy and clinical immunology.
2019
Academic Article
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Times cited: 50 -
Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2019
Academic Article
GET IT
Times cited: 46 -
Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.
The Journal of allergy and clinical immunology.
2019
Academic Article
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Times cited: 26 -
Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis.
The Journal of allergy and clinical immunology.
2019
Academic Article
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Times cited: 77 -
Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial.
Lancet (London, England).
2019
Academic Article
GET IT
Times cited: 150 -
Contribution of fibroblasts to tunnel formation and inflammation in hidradenitis suppurativa/ acne inversa.
Experimental dermatology.
2019
Review
GET IT
Times cited: 24 -
IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis.
The Journal of investigative dermatology.
2019
Academic Article
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Times cited: 107 -
IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis.
The Journal of allergy and clinical immunology.
2019
Academic Article
GET IT
Times cited: 73 -
Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals.
The Journal of investigative dermatology.
2019
Letter
GET IT
Times cited: 15 -
Inter-rater reliability of phenotypes and exploratory genotype-phenotype analysis in inherited hidradenitis suppurativa.
The British journal of dermatology.
2019
Academic Article
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Times cited: 30 -
The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease.
Journal of the American Academy of Dermatology.
2019
Academic Article
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Times cited: 57 -
The skin as an immune organ: Tolerance versus effector responses and applications to food allergy and hypersensitivity reactions.
The Journal of allergy and clinical immunology.
2019
Academic Article
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Times cited: 31 -
Inflammasome Signaling and Impaired Vascular Health in Psoriasis.
Arteriosclerosis, thrombosis, and vascular biology.
2019
Academic Article
GET IT
Times cited: 51 -
A randomized, double-blind, placebo-controlled phase 1 study of multiple ascending doses of subcutaneous M1095, an anti-interleukin 17A/F nanobody, in moderate-to-severe psoriasis.
Journal of the American Academy of Dermatology.
2019
Academic Article
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Times cited: 37 -
Topical, systemic and biologic therapies in hidradenitis suppurativa: pathogenic insights by examining therapeutic mechanisms.
Therapeutic advances in chronic disease.
2019
Review
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Times cited: 29 -
The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis.
Rheumatology (Oxford, England).
2019
Review
GET IT
Times cited: 60 -
Modulation of inflammatory gene transcripts in psoriasis vulgaris: Differences between ustekinumab and etanercept.
The Journal of allergy and clinical immunology.
2019
Letter
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Times cited: 25 -
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
The Journal of allergy and clinical immunology.
2019
Academic Article
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Times cited: 67 -
Hyperspectral imaging in automated digital dermoscopy screening for melanoma.
Lasers in surgery and medicine.
2019
Academic Article
GET IT
Times cited: 24 -
Atopic dermatitis endotypes and implications for targeted therapeutics.
The Journal of allergy and clinical immunology.
2019
Review
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Times cited: 161 -
Novel immune signatures associated with dysplastic naevi and primary cutaneous melanoma in human skin.
Experimental dermatology.
2018
Academic Article
GET IT
Times cited: 12 -
Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab.
The Journal of allergy and clinical immunology.
2018
Academic Article
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Times cited: 42 -
Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases.
The Journal of allergy and clinical immunology.
2018
Academic Article
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Times cited: 22 -
A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativa.
F1000Research.
2018
Academic Article
GET IT
Times cited: 57 -
A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa.
F1000Research.
2018
Academic Article
GET IT
Times cited: 21 -
Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2018
Academic Article
GET IT
Times cited: 31 -
Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge.
The Journal of infectious diseases.
2018
Academic Article
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Times cited: 10 -
Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis.
Journal of immunology (Baltimore, Md. : 1950).
2018
Review
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Times cited: 294 -
Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2018
Academic Article
GET IT
Times cited: 115 -
Skin resident memory CD8+ T cells are phenotypically and functionally distinct from circulating populations and lack immediate cytotoxic function.
Clinical and experimental immunology.
2018
Academic Article
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Times cited: 22 -
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis.
The Journal of allergy and clinical immunology.
2018
Academic Article
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Times cited: 318 -
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab.
The Journal of allergy and clinical immunology.
2018
Academic Article
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Times cited: 110 -
Mechanisms Underlying the Clinical Effects of Apremilast for Psoriasis.
Journal of drugs in dermatology : JDD.
2018
Review
GET IT
Times cited: 51 -
The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses.
The Journal of experimental medicine.
2018
Academic Article
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Times cited: 76 -
An integrated model of alopecia areata biomarkers highlights both TH1 and TH2 upregulation.
The Journal of allergy and clinical immunology.
2018
Letter
GET IT
Times cited: 28 -
IL-17C: A Unique Epithelial Cytokine with Potential for Targeting across the Spectrum of Atopic Dermatitis and Psoriasis.
The Journal of investigative dermatology.
2018
Comment
GET IT
Times cited: 45 -
Atopic dermatitis in Chinese patients shows TH2/TH17 skewing with psoriasiform features.
The Journal of allergy and clinical immunology.
2018
Letter
GET IT
Times cited: 61 -
Synergistic cytokine effects as apremilast response predictors in patients with psoriasis.
The Journal of allergy and clinical immunology.
2018
Letter
GET IT
Times cited: 24 -
Proportion of CD4+CD49b+LAG-3+ Type 1 Regulatory T Cells in the Blood of Psoriasis Patients Inversely Correlates with Psoriasis Area and Severity Index.
The Journal of investigative dermatology.
2018
Letter
GET IT
Times cited: 18 -
Author Correction: The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins.
Scientific reports.
2018
Article
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Times cited: 6 -
Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature.
The Journal of allergy and clinical immunology.
2018
Academic Article
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Times cited: 62 -
Early-onset pediatric atopic dermatitis is characterized by TH2/TH17/TH22-centered inflammation and lipid alterations.
The Journal of allergy and clinical immunology.
2018
Academic Article
GET IT
Times cited: 151 -
The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood.
The Journal of investigative dermatology.
2018
Academic Article
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Times cited: 37 -
Serum from Asian patients with atopic dermatitis is characterized by TH2/TH22 activation, which is highly correlated with nonlesional skin measures.
The Journal of allergy and clinical immunology.
2018
Letter
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Times cited: 36 -
Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment.
Therapeutic advances in chronic disease.
2018
Academic Article
GET IT
Times cited: 65 - The Rockefeller University Clinical Scholars (KL2) Program 2006-2016. Journal of clinical and translational science. 2018 Academic Article GET IT
-
Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial.
Journal of the American Academy of Dermatology.
2018
Academic Article
GET IT
Times cited: 198 -
Interleukin-17 alters the biology of many cell types involved in the genesis of psoriasis, systemic inflammation and associated comorbidities.
Experimental dermatology.
2017
Review
GET IT
Times cited: 79 -
Alopecia areata is characterized by expansion of circulating Th2/Tc2/Th22, within the skin-homing and systemic T-cell populations.
Allergy.
2017
Academic Article
GET IT
Times cited: 39 -
Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation.
The Journal of allergy and clinical immunology.
2017
Academic Article
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Times cited: 60 -
Dust mite induces multiple polar T cell axes in human skin.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2017
Academic Article
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Times cited: 22 -
Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones.
The Journal of clinical investigation.
2017
Academic Article
GET IT
Times cited: 159 -
Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment.
The Journal of investigative dermatology.
2017
Academic Article
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Times cited: 35 -
Atopic dermatitis and psoriasis: two different immune diseases or one spectrum?.
Current opinion in immunology.
2017
Review
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Times cited: 208 -
Psoriasis pathogenesis and the development of novel targeted immune therapies.
The Journal of allergy and clinical immunology.
2017
Review
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Times cited: 502 -
The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins.
Scientific reports.
2017
Academic Article
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Times cited: 145 -
Identification of unique proteomic signatures in allergic and non-allergic skin disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2017
Academic Article
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Times cited: 36 -
Line scanning, stage scanning confocal microscope (LSSSCM).
Biomedical optics express.
2017
Academic Article
GET IT
Times cited: 10 -
Autoantigens ADAMTSL5 and LL37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes.
Experimental dermatology.
2017
Academic Article
GET IT
Times cited: 72 -
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.
Cell.
2017
Academic Article
GET IT
Times cited: 118 -
Nonlesional atopic dermatitis skin shares similar T-cell clones with lesional tissues.
Allergy.
2017
Academic Article
GET IT
Times cited: 53 - Response to Hjuler et al. The Journal of investigative dermatology. 2017 Comment GET IT
-
Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march.
The Journal of allergy and clinical immunology.
2017
Review
GET IT
Times cited: 170 -
The management of moderate-to-severe chronic plaque psoriasis.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia.
2017
Review
GET IT
Times cited: 2 -
Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment.
Experimental dermatology.
2017
Review
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Times cited: 121 -
Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting.
The Journal of rheumatology.
2017
Academic Article
GET IT
Times cited: 2 -
Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis.
The New England journal of medicine.
2017
Academic Article
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Times cited: 343 -
Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10.
Journal of immunology (Baltimore, Md. : 1950).
2017
Academic Article
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Times cited: 55 -
Expression of Programmed Cell Death Ligand in Cutaneous Squamous Cell Carcinoma and Treatment of Locally Advanced Disease With Pembrolizumab.
2017
GET IT
Times cited: 80 -
TNF-α Antagonist and Vascular Inflammation in Patients with Psoriasis Vulgaris: A Randomized Placebo-Controlled Study.
The Journal of investigative dermatology.
2017
Academic Article
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Times cited: 78 -
Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans.
Experimental dermatology.
2017
Academic Article
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Times cited: 21 -
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism.
Nature.
2017
Academic Article
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Times cited: 408 -
Patch testing of food allergens promotes Th17 and Th2 responses with increased IL-33: a pilot study.
Experimental dermatology.
2017
Letter
GET IT
Times cited: 11 -
Digital imaging biomarkers feed machine learning for melanoma screening.
Experimental dermatology.
2016
Letter
GET IT
Times cited: 22 -
Alterations in B-cell subsets in pediatric patients with early atopic dermatitis.
The Journal of allergy and clinical immunology.
2016
Academic Article
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Times cited: 39 -
MAGEA3 Expression in Cutaneous Squamous Cell Carcinoma Is Associated with Advanced Tumor Stage and Poor Prognosis.
The Journal of investigative dermatology.
2016
Letter
GET IT
Times cited: 11 -
An Integrated Model of Atopic Dermatitis Biomarkers Highlights the Systemic Nature of the Disease.
The Journal of investigative dermatology.
2016
Academic Article
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Times cited: 127 -
Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.
The Journal of allergy and clinical immunology.
2016
Academic Article
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Times cited: 81 -
Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway.
Journal of dermatological science.
2016
Academic Article
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Times cited: 32 -
Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin.
The Journal of allergy and clinical immunology.
2016
Letter
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Times cited: 263 -
Highly Effective New Treatments for Psoriasis Target the IL-23/Type 17 T Cell Autoimmune Axis.
Annual review of medicine.
2016
Review
GET IT
Times cited: 116 -
Shrinking the Psoriasis Assessment Gap: Early Gene-Expression Profiling Accurately Predicts Response to Long-Term Treatment.
The Journal of investigative dermatology.
2016
Academic Article
GET IT
Times cited: 41 - Cutaneous Expression of A Disintegrin-like and Metalloprotease domain containing Thrombospondin Type 1 motif-like 5 (ADAMTSL5) in Psoriasis goes beyond Melanocytes. Journal of pigmentary disorders. 2016 Academic Article GET IT
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An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis.
The Journal of allergy and clinical immunology.
2016
Academic Article
GET IT
Times cited: 105 -
Efficacy and safety of ustekinumab treatment in adults with moderate-to-severe atopic dermatitis.
Experimental dermatology.
2016
Academic Article
GET IT
Times cited: 170 -
Definite regression of cutaneous melanoma metastases upon addition of topical contact sensitizer diphencyprone to immune checkpoint inhibitor treatment.
Experimental dermatology.
2016
Letter
GET IT
Times cited: 14 -
Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria.
The Journal of investigative dermatology.
2016
Academic Article
GET IT
Times cited: 27 -
Molecular Profiling of Immune Activation Associated with Regression of Melanoma Metastases Induced by Diphencyprone.
The Journal of investigative dermatology.
2016
Letter
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Times cited: 6 -
A prospective phase III, randomized, double-blind, placebo-controlled study of brodalumab in patients with moderate-to-severe plaque psoriasis.
The British journal of dermatology.
2016
Academic Article
GET IT
Times cited: 343 -
Correction: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris.
PloS one.
2016
Article
GET IT
Times cited: 1 -
Accelerated T-cell activation and differentiation of polar subsets characterizes early atopic dermatitis development.
The Journal of allergy and clinical immunology.
2016
Letter
GET IT
Times cited: 27 -
Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.
JCI insight.
2016
Academic Article
GET IT
Times cited: 31 -
Cutaneous Adverse Events in the Randomized, Double-Blind, Active-Comparator DECIDE Study of Daclizumab High-Yield Process Versus Intramuscular Interferon Beta-1a in Relapsing-Remitting Multiple Sclerosis.
Advances in therapy.
2016
Academic Article
GET IT
Times cited: 27 -
Lipoprotein Metabolism and Inflammation in Patients With Psoriasis.
The American journal of cardiology.
2016
Review
GET IT
Times cited: 21 -
The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.
The Journal of investigative dermatology.
2016
Academic Article
GET IT
Times cited: 37 -
Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris.
PloS one.
2016
Academic Article
GET IT
Times cited: 38 -
IL-32 induces indoleamine 2,3-dioxygenase+CD1c+ dendritic cells and indoleamine 2,3-dioxygenase+CD163+ macrophages: Relevance to mycosis fungoides progression.
Oncoimmunology.
2016
Academic Article
GET IT
Times cited: 22 -
Efficacy of Tofacitinib for the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis in Patient Subgroups from Two Randomised Phase 3 Trials.
Journal of drugs in dermatology : JDD.
2016
Academic Article
GET IT
Times cited: 21 -
New therapies for psoriasis and psoriatic arthritis.
Current opinion in rheumatology.
2016
Review
GET IT
Times cited: 56 - Reply. The Journal of allergy and clinical immunology. 2016 Letter GET IT
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Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study.
The Journal of allergy and clinical immunology.
2016
Academic Article
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Times cited: 106 -
Methotrexate improves pro- and anti-atherogenic genomic expression in psoriatic skin.
Journal of dermatological science.
2016
Letter
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Times cited: 3 -
Biomarkers of alopecia areata disease activity and response to corticosteroid treatment.
Experimental dermatology.
2016
Academic Article
GET IT
Times cited: 55 -
A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis.
The Journal of allergy and clinical immunology.
2016
Academic Article
GET IT
Times cited: 56 -
Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: Long-term efficacy and safety results from 2 randomized phase-III studies and 1 open-label long-term extension study.
Journal of the American Academy of Dermatology.
2016
Academic Article
GET IT
Times cited: 111 -
Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis.
PloS one.
2016
Academic Article
GET IT
Times cited: 33 -
Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets.
The Journal of investigative dermatology.
2016
Academic Article
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Times cited: 44 -
The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.
The Journal of allergy and clinical immunology.
2015
Academic Article
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Times cited: 82 -
An autoimmune "attack" on melanocytes triggers psoriasis and cellular hyperplasia.
The Journal of experimental medicine.
2015
Comment
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Times cited: 20 -
Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism.
The Journal of allergy and clinical immunology.
2015
Letter
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Times cited: 64 -
Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris.
The British journal of dermatology.
2015
Review
GET IT
Times cited: 65 -
A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis.
PloS one.
2015
Academic Article
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Times cited: 61 -
Tildrakizumab (MK-3222), an anti-interleukin-23p19 monoclonal antibody, improves psoriasis in a phase IIb randomized placebo-controlled trial.
The British journal of dermatology.
2015
Academic Article
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Times cited: 218 -
Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways.
BMC medical genomics.
2015
Review
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Times cited: 110 - Reply: To PMID 25748064. The Journal of allergy and clinical immunology. 2015 Letter GET IT
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TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL.
Science translational medicine.
2015
Academic Article
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Times cited: 133 -
Diverse activation and differentiation of multiple B-cell subsets in patients with atopic dermatitis but not in patients with psoriasis.
The Journal of allergy and clinical immunology.
2015
Academic Article
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Times cited: 83 -
Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer.
The Journal of allergy and clinical immunology.
2015
Academic Article
GET IT
Times cited: 108 -
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.
The Journal of allergy and clinical immunology.
2015
Academic Article
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Times cited: 391 -
Unique microRNAs appear at different times during the course of a delayed-type hypersensitivity reaction in human skin.
Experimental dermatology.
2015
Academic Article
GET IT
Times cited: 16 -
Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.
The Journal of allergy and clinical immunology.
2015
Academic Article
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Times cited: 161 -
First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis.
PloS one.
2015
Academic Article
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Times cited: 15 -
Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis.
F1000Research.
2015
Academic Article
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Times cited: 546 -
CCL20 and IL22 Messenger RNA Expression After Adalimumab vs Methotrexate Treatment of Psoriasis: A Randomized Clinical Trial.
JAMA dermatology.
2015
Academic Article
GET IT
Times cited: 35 -
Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets.
The Journal of allergy and clinical immunology.
2015
Academic Article
GET IT
Times cited: 151 -
The immunogenetics of Psoriasis: A comprehensive review.
Journal of autoimmunity.
2015
Review
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Times cited: 362 -
Histological Stratification of Thick and Thin Plaque Psoriasis Explores Molecular Phenotypes with Clinical Implications.
PloS one.
2015
Academic Article
GET IT
Times cited: 20 -
A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis.
The British journal of dermatology.
2015
Academic Article
GET IT
Times cited: 75 -
Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions.
F1000Research.
2015
Academic Article
GET IT
Times cited: 591 -
Common clonal origin of central and resident memory T cells following skin immunization.
Nature medicine.
2015
Academic Article
GET IT
Times cited: 209 -
Skin-homing and systemic T-cell subsets show higher activation in atopic dermatitis versus psoriasis.
The Journal of allergy and clinical immunology.
2015
Letter
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Times cited: 62 -
Aurora Kinase A Is Upregulated in Cutaneous T-Cell Lymphoma and Represents a Potential Therapeutic Target.
The Journal of investigative dermatology.
2015
Academic Article
GET IT
Times cited: 21 -
Comparative genomic profiling of synovium versus skin lesions in psoriatic arthritis.
Arthritis & rheumatology (Hoboken, N.J.).
2015
Academic Article
GET IT
Times cited: 87 -
RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications.
The Journal of allergy and clinical immunology.
2015
Academic Article
GET IT
Times cited: 191 -
Anti-IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial.
The Journal of allergy and clinical immunology.
2015
Academic Article
GET IT
Times cited: 199 -
Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population.
The Journal of allergy and clinical immunology.
2015
Academic Article
GET IT
Times cited: 158 -
The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.
The Journal of investigative dermatology.
2015
Academic Article
GET IT
Times cited: 67 -
Laser capture microdissection followed by next-generation sequencing identifies disease-related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis.
Experimental dermatology.
2015
Academic Article
GET IT
Times cited: 61 -
Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin.
The Journal of allergy and clinical immunology.
2015
Academic Article
GET IT
Times cited: 55 -
Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.
The Journal of allergy and clinical immunology.
2015
Academic Article
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Times cited: 149 -
The immunopathogenesis of psoriasis.
Dermatologic clinics.
2015
Review
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Times cited: 236 -
The translational revolution and use of biologics in patients with inflammatory skin diseases.
The Journal of allergy and clinical immunology.
2014
Review
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Times cited: 158 -
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis.
The Journal of allergy and clinical immunology.
2014
Academic Article
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Times cited: 329 -
Dendritic cells are contained within melanocytic nevus nests in vivo and can alter gene expression of epidermal melanocytes in vitro.
Pigment cell & melanoma research.
2014
Letter
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Times cited: 2 -
Deficient cutaneous antibacterial competence in cutaneous T-cell lymphomas: role of Th2-mediated biased Th17 function.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014
Academic Article
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Times cited: 54 -
Accumulating evidence for the association and shared pathogenic mechanisms between psoriasis and cardiovascular-related comorbidities.
The American journal of medicine.
2014
Review
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Times cited: 54 -
Humanized anti-IFN-γ (HuZAF) in the treatment of psoriasis.
The Journal of allergy and clinical immunology.
2014
Letter
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Times cited: 75 -
IL-17 induces inflammation-associated gene products in blood monocytes, and treatment with ixekizumab reduces their expression in psoriasis patient blood.
The Journal of investigative dermatology.
2014
Letter
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Times cited: 44 -
Residual genomic profile after cyclosporine treatment may offer insights into atopic dermatitis reoccurrence.
The Journal of allergy and clinical immunology.
2014
Letter
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Times cited: 20 -
IL32 is progressively expressed in mycosis fungoides independent of helper T-cell 2 and helper T-cell 9 polarization.
Cancer immunology research.
2014
Academic Article
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Times cited: 18 -
Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology.
The Journal of allergy and clinical immunology.
2014
Academic Article
GET IT
Times cited: 128 -
Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.
The Journal of allergy and clinical immunology.
2014
Academic Article
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Times cited: 191 -
Skin barrier and immune dysregulation in atopic dermatitis: an evolving story with important clinical implications.
The journal of allergy and clinical immunology. In practice.
2014
Review
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Times cited: 135 -
Molecular characterization of human skin response to diphencyprone at peak and resolution phases: therapeutic insights.
The Journal of investigative dermatology.
2014
Academic Article
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Times cited: 33 -
Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis.
The Journal of allergy and clinical immunology.
2014
Academic Article
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Times cited: 240 -
Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950).
2014
Academic Article
GET IT
Times cited: 123 -
IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.
PloS one.
2014
Academic Article
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Times cited: 135 -
Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?.
Expert opinion on therapeutic targets.
2014
Review
GET IT
Times cited: 49 -
Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper.
The Journal of dermatological treatment.
2014
Review
GET IT
Times cited: 39 -
Immunology of psoriasis.
Annual review of immunology.
2014
Review
GET IT
Times cited: 1033 -
Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation.
PloS one.
2013
Academic Article
GET IT
Times cited: 88 -
Dermal clusters of mature dendritic cells and T cells are associated with the CCL20/CCR6 chemokine system in chronic psoriasis.
The Journal of investigative dermatology.
2013
Letter
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Times cited: 64 -
Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma.
Oncotarget.
2013
Academic Article
GET IT
Times cited: 19 -
Gene expression profiling of the leading edge of cutaneous squamous cell carcinoma: IL-24-driven MMP-7.
The Journal of investigative dermatology.
2013
Academic Article
GET IT
Times cited: 51 -
An animal explant model for the study of human cutaneous squamous cell carcinoma.
PloS one.
2013
Academic Article
GET IT
Times cited: 2 -
Increased expression of IL-17A and limited involvement of IL-23 in patients with palmo-plantar (PP) pustular psoriasis or PP pustulosis; results from a randomised controlled trial.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2013
Academic Article
GET IT
Times cited: 76 -
Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis.
Journal of translational medicine.
2013
Academic Article
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Times cited: 37 -
Efficacy, tolerability, and pharmacodynamics of apremilast in recalcitrant plaque psoriasis: a phase II open-label study.
Journal of drugs in dermatology : JDD.
2013
Academic Article
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Times cited: 77 -
Attenuated neutrophil axis in atopic dermatitis compared to psoriasis reflects TH17 pathway differences between these diseases.
The Journal of allergy and clinical immunology.
2013
Letter
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Times cited: 33 -
Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.
The Journal of allergy and clinical immunology.
2013
Academic Article
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Times cited: 342 -
Dominant Th1 and minimal Th17 skewing in discoid lupus revealed by transcriptomic comparison with psoriasis.
The Journal of investigative dermatology.
2013
Academic Article
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Times cited: 85 -
IL-17 targeted therapies for psoriasis.
Expert opinion on investigational drugs.
2013
Review
GET IT
Times cited: 129 -
Increased Tc22 and Treg/CD8 ratio contribute to aggressive growth of transplant associated squamous cell carcinoma.
PloS one.
2013
Academic Article
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Times cited: 64 -
Atypical erythema migrans in patients with PCR-positive Lyme disease.
Emerging infectious diseases.
2013
Letter
GET IT
Times cited: 35 -
IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis.
The Journal of investigative dermatology.
2013
Academic Article
GET IT
Times cited: 132 -
Creation of differentiation-specific genomic maps of human epidermis through laser capture microdissection.
The Journal of investigative dermatology.
2013
Letter
GET IT
Times cited: 13 -
CD200 upregulation in vascular endothelium surrounding cutaneous squamous cell carcinoma.
JAMA dermatology.
2013
Academic Article
GET IT
Times cited: 25 -
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.
Trends in immunology.
2013
Review
GET IT
Times cited: 348 -
Residual genomic signature of atopic dermatitis despite clinical resolution with narrow-band UVB.
The Journal of allergy and clinical immunology.
2012
Letter
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Times cited: 26 -
Hiding under the skin: A welcome surprise in psoriasis.
Nature medicine.
2012
Academic Article
GET IT
Times cited: 41 -
Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses.
The Journal of investigative dermatology.
2012
Academic Article
GET IT
Times cited: 41 -
Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease.
PloS one.
2012
Review
GET IT
Times cited: 141 -
Atopic dermatitis results in intrinsic barrier and immune abnormalities: implications for contact dermatitis.
The Journal of allergy and clinical immunology.
2012
Review
GET IT
Times cited: 167 -
Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.
The Journal of allergy and clinical immunology.
2012
Academic Article
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Times cited: 618 -
Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections.
The Journal of clinical investigation.
2012
Academic Article
GET IT
Times cited: 118 -
Expanding the psoriasis disease profile: interrogation of the skin and serum of patients with moderate-to-severe psoriasis.
The Journal of investigative dermatology.
2012
Academic Article
GET IT
Times cited: 212 -
Putting together the psoriasis puzzle: an update on developing targeted therapies.
Disease models & mechanisms.
2012
Review
GET IT
Times cited: 100 -
The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings.
The Journal of investigative dermatology.
2012
Review
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Times cited: 350 -
IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis.
The Journal of allergy and clinical immunology.
2012
Academic Article
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Times cited: 304 -
Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial.
The Journal of investigative dermatology.
2012
Letter
GET IT
Times cited: 124 -
Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
PloS one.
2012
Academic Article
GET IT
Times cited: 52 -
Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis.
The New England journal of medicine.
2012
Academic Article
GET IT
Times cited: 780 -
Combined use of laser capture microdissection and cDNA microarray analysis identifies locally expressed disease-related genes in focal regions of psoriasis vulgaris skin lesions.
The Journal of investigative dermatology.
2012
Academic Article
GET IT
Times cited: 64 -
Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity.
The Journal of investigative dermatology.
2012
Academic Article
GET IT
Times cited: 31 -
Post-therapeutic relapse of psoriasis after CD11a blockade is associated with T cells and inflammatory myeloid DCs.
PloS one.
2012
Academic Article
GET IT
Times cited: 27 -
A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin.
The Journal of investigative dermatology.
2012
Academic Article
GET IT
Times cited: 78 -
Human keratinocytes' response to injury upregulates CCL20 and other genes linking innate and adaptive immunity.
The Journal of investigative dermatology.
2011
Academic Article
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Times cited: 98 -
Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: a meta-analysis of randomized controlled trials.
JAMA.
2011
Review
GET IT
Times cited: 251 -
Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes.
The Journal of investigative dermatology.
2011
Letter
GET IT
Times cited: 74 -
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response.
The Journal of allergy and clinical immunology.
2011
Academic Article
GET IT
Times cited: 148 -
Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets.
The Journal of allergy and clinical immunology.
2011
Academic Article
GET IT
Times cited: 99 -
Clinical symptoms of skin, nails, and joints manifest independently in patients with concomitant psoriasis and psoriatic arthritis.
PloS one.
2011
Academic Article
GET IT
Times cited: 49 -
Th17 cells and activated dendritic cells are increased in vitiligo lesions.
PloS one.
2011
Academic Article
GET IT
Times cited: 127 -
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.
The Journal of allergy and clinical immunology.
2011
Academic Article
GET IT
Times cited: 318 -
Contrasting pathogenesis of atopic dermatitis and psoriasis--part II: immune cell subsets and therapeutic concepts.
The Journal of allergy and clinical immunology.
2011
Review
GET IT
Times cited: 235 -
Contrasting pathogenesis of atopic dermatitis and psoriasis--part I: clinical and pathologic concepts.
The Journal of allergy and clinical immunology.
2011
Review
GET IT
Times cited: 240 -
TNF-α downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-α antagonists to improve skin barrier.
The Journal of investigative dermatology.
2011
Academic Article
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Times cited: 136 - Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated. The Journal of investigative dermatology. 2011 Academic Article GET IT
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Anti-cytokine therapies for psoriasis.
Experimental cell research.
2011
Review
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Times cited: 43 - Role of the immune system and immunological circuits in psoriasis. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 2011 Review GET IT
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A novel chimeric lysin shows superiority to mupirocin for skin decolonization of methicillin-resistant and -sensitive Staphylococcus aureus strains.
Antimicrobial agents and chemotherapy.
2010
Academic Article
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Times cited: 132 -
Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis.
The Journal of investigative dermatology.
2010
Academic Article
GET IT
Times cited: 436 -
Resolved psoriasis lesions retain expression of a subset of disease-related genes.
The Journal of investigative dermatology.
2010
Academic Article
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Times cited: 136 -
The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C.
The Journal of investigative dermatology.
2010
Academic Article
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Times cited: 85 -
UV radiation inhibits 15-hydroxyprostaglandin dehydrogenase levels in human skin: evidence of transcriptional suppression.
Cancer prevention research (Philadelphia, Pa.).
2010
Academic Article
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Times cited: 15 -
A subpopulation of CD163-positive macrophages is classically activated in psoriasis.
The Journal of investigative dermatology.
2010
Academic Article
GET IT
Times cited: 215 -
Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques.
The Journal of investigative dermatology.
2010
Academic Article
GET IT
Times cited: 120 -
Characterisation of the cutaneous pathology in non-small cell lung cancer (NSCLC) patients treated with the EGFR tyrosine kinase inhibitor erlotinib.
European journal of cancer (Oxford, England : 1990).
2010
Academic Article
GET IT
Times cited: 61 -
Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis.
The Journal of allergy and clinical immunology.
2010
Academic Article
GET IT
Times cited: 82 -
Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions.
The Journal of investigative dermatology.
2010
Review
GET IT
Times cited: 550 -
Evaluation of the psoriasis transcriptome across different studies by gene set enrichment analysis (GSEA).
PloS one.
2010
Academic Article
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Times cited: 145 -
Differing effect of systemic anti psoriasis therapies on platelet physiology--a case report and review of literature.
BMC dermatology.
2010
Review
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Times cited: 9 -
Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses.
The Journal of allergy and clinical immunology.
2010
Letter
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Times cited: 29 -
New insights in the immunologic basis of psoriasis.
Seminars in cutaneous medicine and surgery.
2010
Review
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Times cited: 164 -
Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept.
BMC dermatology.
2010
Academic Article
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Times cited: 31 -
Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production.
Proceedings of the National Academy of Sciences of the United States of America.
2009
Academic Article
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Times cited: 205 -
Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis.
The Journal of allergy and clinical immunology.
2009
Academic Article
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Times cited: 203 -
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes.
The Journal of allergy and clinical immunology.
2009
Academic Article
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Times cited: 257 -
Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging.
The Journal of experimental medicine.
2009
Academic Article
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Times cited: 135 -
IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.
The Journal of allergy and clinical immunology.
2009
Academic Article
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Times cited: 513 -
Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation.
The Journal of investigative dermatology.
2009
Academic Article
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Times cited: 65 -
Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases.
Journal of clinical immunology.
2009
Review
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Times cited: 82 -
Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis.
The Journal of investigative dermatology.
2009
Letter
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Times cited: 131 -
AJC editor's consensus: psoriasis and coronary artery disease.
The American journal of cardiology.
2008
Review
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Times cited: 145 -
Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
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Times cited: 286 -
Resident and "inflammatory" dendritic cells in human skin.
The Journal of investigative dermatology.
2008
Review
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Times cited: 254 -
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.
The British journal of dermatology.
2008
Academic Article
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Times cited: 671 -
Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells.
The Journal of investigative dermatology.
2008
Academic Article
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Times cited: 355 -
Type I interferon: potential therapeutic target for psoriasis?.
PloS one.
2008
Academic Article
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Times cited: 237 -
Analytical approaches to reporting long-term clinical trial data.
Current medical research and opinion.
2008
Academic Article
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Times cited: 33 -
Effect of therapeutic integrin (CD11a) blockade with efalizumab on immune responses to model antigens in humans: results of a randomized, single blind study.
The Journal of investigative dermatology.
2008
Academic Article
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Times cited: 26 -
An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent, apremilast.
Current medical research and opinion.
2008
Academic Article
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Times cited: 111 -
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
PLoS genetics.
2008
Academic Article
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Times cited: 566 -
Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
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Times cited: 151 -
Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness.
The Journal of investigative dermatology.
2008
Academic Article
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Times cited: 56 -
Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.
The Journal of investigative dermatology.
2008
Academic Article
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Times cited: 860 -
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses.
The Journal of experimental medicine.
2007
Academic Article
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Times cited: 546 -
Cellular genomic maps help dissect pathology in human skin disease.
The Journal of investigative dermatology.
2007
Academic Article
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Times cited: 28 -
Insights into gene modulation by therapeutic TNF and IFNgamma antibodies: TNF regulates IFNgamma production by T cells and TNF-regulated genes linked to psoriasis transcriptome.
The Journal of investigative dermatology.
2007
Academic Article
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Times cited: 29 -
Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages.
The Journal of clinical investigation.
2007
Academic Article
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Times cited: 246 -
Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research.
The British journal of dermatology.
2007
Review
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Times cited: 57 -
Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis.
Journal of translational medicine.
2007
Academic Article
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Times cited: 57 -
Novel insight into the agonistic mechanism of alefacept in vivo: differentially expressed genes may serve as biomarkers of response in psoriasis patients.
Journal of immunology (Baltimore, Md. : 1950).
2007
Academic Article
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Times cited: 47 -
Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment.
The Journal of investigative dermatology.
2007
Academic Article
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Times cited: 109 -
Effects of etanercept are distinct from infliximab in modulating proinflammatory genes in activated human leukocytes.
The journal of investigative dermatology. Symposium proceedings.
2007
Academic Article
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Times cited: 41 -
Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis.
The Journal of allergy and clinical immunology.
2007
Academic Article
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Times cited: 187 -
Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case series.
BMC dermatology.
2007
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Times cited: 19 -
Pathogenesis and therapy of psoriasis.
Nature.
2007
Review
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Times cited: 1436 -
Psoriasis: genetic associations and immune system changes.
Genes and immunity.
2006
Review
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Times cited: 153 -
Characterization of the divergent wound-healing responses occurring in the pathergy reaction and normal healthy volunteers.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
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Times cited: 60 -
Etanercept induces apoptosis of dermal dendritic cells in psoriatic plaques of responding patients.
Journal of the American Academy of Dermatology.
2006
Academic Article
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Times cited: 57 -
Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects.
The Journal of investigative dermatology.
2006
Academic Article
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Times cited: 86 -
Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia.
The Journal of investigative dermatology.
2006
Academic Article
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Times cited: 160 -
Increased JunB mRNA and protein expression in psoriasis vulgaris lesions.
The Journal of investigative dermatology.
2006
Letter
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Times cited: 37 -
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Getting under the skin: the immunogenetics of psoriasis.
Nature reviews. Immunology.
2005
Review
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Times cited: 403 -
Psoriasis vulgaris flare during efalizumab therapy does not preclude future use: a case series.
2005
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Times cited: 33 -
TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques.
Journal of immunology (Baltimore, Md. : 1950).
2005
Academic Article
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Times cited: 322 -
HER1/EGFR inhibitor-associated rash: future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum.
The oncologist.
2005
Review
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Times cited: 259 -
Pharmacokinetics and pharmacodynamics of multiple weekly subcutaneous efalizumab doses in patients with plaque psoriasis.
Journal of clinical pharmacology.
2005
Academic Article
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Times cited: 65 -
Psoriasis pathophysiology: current concepts of pathogenesis.
Annals of the rheumatic diseases.
2005
Review
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Times cited: 408 -
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Times cited: 204 -
Current concepts in the immunopathogenesis of psoriasis.
Dermatologic clinics.
2004
Review
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Times cited: 47 -
Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin.
Clinical immunology (Orlando, Fla.).
2004
Academic Article
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Times cited: 79 -
Psoriasis vulgaris: an interplay of T lymphocytes, dendritic cells, and inflammatory cytokines in pathogenesis.
Current opinion in rheumatology.
2004
Review
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Times cited: 65 - A 50% reduction in the Psoriasis Area and Severity Index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis. Journal of the American Academy of Dermatology. 2004 Academic Article GET IT
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Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression.
Trends in immunology.
2004
Review
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Times cited: 237 -
Combining several ordinal measures in clinical studies.
Statistics in medicine.
2004
Academic Article
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Times cited: 66 -
Psoriasis genomics: analysis of proinflammatory (type 1) gene expression in large plaque (Western) and small plaque (Asian) psoriasis vulgaris.
The British journal of dermatology.
2004
Academic Article
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Times cited: 58 -
Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris.
The Journal of experimental medicine.
2004
Academic Article
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Times cited: 786 -
A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis.
Nature genetics.
2003
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Times cited: 264 -
Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array.
Physiological genomics.
2003
Academic Article
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Narrowband (312-nm) UV-B suppresses interferon gamma and interleukin (IL) 12 and increases IL-4 transcripts: differential regulation of cytokines at the single-cell level.
Archives of dermatology.
2003
Academic Article
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Times cited: 77 -
Psoriasis as a model for T-cell-mediated disease: immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody.
Archives of dermatology.
2002
Academic Article
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Times cited: 232 -
A humanized non-FcR-binding anti-CD3 antibody, visilizumab, for treatment of steroid-refractory acute graft-versus-host disease.
Blood.
2002
Academic Article
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Times cited: 147 -
Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement.
Clinical immunology (Orlando, Fla.).
2002
Academic Article
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The immunologic basis for the treatment of psoriasis with new biologic agents.
Journal of the American Academy of Dermatology.
2002
Review
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Treatment of inflammatory dermatoses with novel biologic agents: a primer.
Advances in dermatology.
2002
Review
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The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody.
Journal of the American Academy of Dermatology.
2001
Academic Article
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Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris.
Laboratory investigation; a journal of technical methods and pathology.
2001
Academic Article
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Times cited: 193 -
Microdialysis can detect age-related differences in glucose distribution within the dermis and subcutaneous adipose tissue.
Dermatology (Basel, Switzerland).
2001
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Times cited: 6 -
Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling.
The pharmacogenomics journal.
2001
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Anti-CD4 monoclonal antibody treatment of moderate to severe psoriasis vulgaris: results of a pilot, multicenter, multiple-dose, placebo-controlled study.
Journal of the American Academy of Dermatology.
2000
Academic Article
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Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells.
The Journal of experimental medicine.
2000
Academic Article
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Times cited: 302 - Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis. Journal of the American Academy of Dermatology. 2000 Academic Article GET IT
- Anti-CD11a treatment for psoriasis concurrently increases circulating T-cells and decreases plaque T-cells, consistent with inhibition of cutaneous T-cell trafficking. The Journal of investigative dermatology. 2000 Academic Article GET IT
- Two considerations for patients with psoriasis and their clinicians: what defines mild, moderate, and severe psoriasis? What constitutes a clinically significant improvement when treating psoriasis?. Journal of the American Academy of Dermatology. 2000 Academic Article GET IT
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Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis.
Journal of the American Academy of Dermatology.
2000
Academic Article
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CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry.
Journal of autoimmunity.
2000
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Clinical clearing of psoriasis by 6-thioguanine correlates with cutaneous T-cell depletion via apoptosis: evidence for selective effects on activated T lymphocytes.
Archives of dermatology.
1999
Academic Article
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Times cited: 23 -
Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.
The Journal of clinical investigation.
1999
Academic Article
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Times cited: 209 -
The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients.
The Journal of investigative dermatology.
1999
Academic Article
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Times cited: 438 -
Suberythemogenic narrow-band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris.
Journal of the American Academy of Dermatology.
1999
Academic Article
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Times cited: 167 -
CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris.
The Journal of clinical investigation.
1999
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312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions.
The Journal of experimental medicine.
1999
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PUVA-induced lymphocyte apoptosis: mechanism of action in psoriasis.
Photodermatology, photoimmunology & photomedicine.
1999
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Trimethylpsoralen bath PUVA is a remittive treatment for psoriasis vulgaris. Evidence that epidermal immunocytes are direct therapeutic targets.
Archives of dermatology.
1998
Academic Article
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Times cited: 35 -
An exploratory investigation of the morphology and biochemistry of cellulite.
Plastic and reconstructive surgery.
1998
Academic Article
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Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17(TIA-1)+CD8+CD3+ CTLs as determined by phenotypic analysis.
Journal of cutaneous pathology.
1998
Academic Article
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Times cited: 69 -
Diphtheria toxin fusion proteins.
Current topics in microbiology and immunology.
1998
Review
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Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L).
The Journal of clinical investigation.
1998
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Altered expression of keratinocyte growth factor and its receptor in psoriasis.
The American journal of pathology.
1997
Academic Article
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Times cited: 111 -
Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B.
Archives of dermatology.
1997
Academic Article
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Times cited: 229 -
Identification of a novel keratinocyte mitogen derived from bovine pituitary glands.
Archives of dermatological research.
1997
Academic Article
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Times cited: 5 -
Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique.
The Journal of investigative dermatology.
1997
Academic Article
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Cellular actions of etretinate in psoriasis: enhanced epidermal differentiation and reduced cell-mediated inflammation are unexpected outcomes.
Journal of cutaneous pathology.
1996
Academic Article
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Times cited: 51 -
Modulation of epidermal differentiation, tissue inflammation, and T-lymphocyte infilitration in psoriatic plaques by topical calcitriol.
Journal of cutaneous pathology.
1996
Academic Article
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Times cited: 24 -
PUVA treatment selectively induces a cell cycle block and subsequent apoptosis in human T-lymphocytes.
Photochemistry and photobiology.
1996
Academic Article
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The insulin-like growth factor 1 receptor is expressed by epithelial cells with proliferative potential in human epidermis and skin appendages: correlation of increased expression with epidermal hyperplasia.
The Journal of investigative dermatology.
1996
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Times cited: 117 -
In vivo expression of the insulin-like growth factor-I (IGF-I) receptor in congenital pigmented nevi.
Journal of cutaneous pathology.
1996
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Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells.
The Journal of experimental medicine.
1995
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Short-contact anthralin treatment augments therapeutic efficacy of cyclosporine in psoriasis: a clinical and pathologic study.
Journal of the American Academy of Dermatology.
1995
Academic Article
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Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis.
Nature medicine.
1995
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GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo.
The Journal of investigative dermatology.
1994
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PUVA bath therapy strongly suppresses immunological and epidermal activation in psoriasis: a possible cellular basis for remittive therapy.
The Journal of experimental medicine.
1994
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E-cadherin distribution in interleukin 6-induced cell-cell separation of ductal breast carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America.
1994
Academic Article
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Times cited: 30 -
Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America.
1994
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Inactivation of c-Yes tyrosine kinase by elevation of intracellular calcium levels.
Molecular and cellular biology.
1993
Academic Article
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Times cited: 34 -
Human interferon-inducible protein 10: expression and purification of recombinant protein demonstrate inhibition of early human hematopoietic progenitors.
The Journal of experimental medicine.
1993
Academic Article
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Human keratinocyte growth factor effects in a porcine model of epidermal wound healing.
The Journal of experimental medicine.
1993
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Human keratinocytes are a major source of cutaneous platelet-derived growth factor.
The Journal of clinical investigation.
1993
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Dissociation between early loss of actin fibres and subsequent cell death in serum-deprived quiescent Balb/c-3T3 cells.
Cellular signalling.
1992
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Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation.
The Journal of clinical investigation.
1992
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Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation.
Proceedings of the National Academy of Sciences of the United States of America.
1992
Academic Article
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Anthralin decreases keratinocyte TGF-alpha expression and EGF-receptor binding in vitro.
The Journal of investigative dermatology.
1992
Academic Article
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Times cited: 34 -
A novel use of the cryptococcal latex agglutination test for rapid presumptive diagnosis of cutaneous cryptococcosis.
1992
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The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor.
The Journal of experimental medicine.
1992
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Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation.
The Journal of investigative dermatology.
1992
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Role of T cell activation in the pathogenesis of psoriasis.
Annals of the New York Academy of Sciences.
1991
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Junctional epidermolysis bullosa keratinocytes in culture display adhesive, structural, and functional abnormalities.
The Journal of investigative dermatology.
1991
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Detection of cytokine-induced protein gamma-immune protein-10 (gamma-IP10) in atypical melanocytic proliferations.
Journal of the American Academy of Dermatology.
1991
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HMB-45 monoclonal antibody recognizes an inducible and reversible melanocyte cytoplasmic protein.
Journal of cutaneous pathology.
1991
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Cyclosporine in psoriasis treatment. Inhibition of keratinocyte cell-cycle progression in G1 independent of effects on transforming growth factor alpha/epidermal growth factor receptor pathways.
Archives of dermatology.
1991
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Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis.
Oncogene.
1991
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Increased dermal expression of platelet-derived growth factor receptors in growth-activated skin wounds and psoriasis.
The Journal of investigative dermatology.
1991
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Expression and function of interleukin-6 in epithelial cells.
Journal of cellular biochemistry.
1991
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Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor.
The Journal of investigative dermatology.
1991
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Fixed drug eruptions: evidence for a cytokine-mediated process.
Journal of cutaneous pathology.
1991
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TGF-alpha and TGF-beta expression during sodium-N-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of TGF-beta mRNA in suprabasal cells.
Experimental cell research.
1990
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Detection of the interferon-gamma-induced protein 10 in psoriasiform dermatitis of acquired immunodeficiency syndrome.
Archives of dermatology.
1990
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Expression of cellular-yes protein in mammalian tissues.
Oncogene.
1990
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HLA region genes and immune activation in the pathogenesis of psoriasis.
Archives of dermatology.
1990
Comment
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Role of growth factors, cytokines, and their receptors in the pathogenesis of psoriasis.
The Journal of investigative dermatology.
1990
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"Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
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Recessive dystrophic epidermolysis bullosa skin displays a chronic growth-activated immunophenotype. Implications for carcinogenesis.
Archives of dermatology.
1990
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Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells.
The Journal of experimental medicine.
1989
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Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.
Proceedings of the National Academy of Sciences of the United States of America.
1989
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Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
1985
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Size-variant pp60src proteins of recovered avian sarcoma viruses interact with adhesion plaques as peripheral membrane proteins: effects on cell transformation.
Molecular and cellular biology.
1984
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Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteins.
Virology.
1983
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Only membrane-associated RSV src proteins have amino-terminally bound lipid.
Nature.
1983
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Novel localization of pp60src in Rous sarcoma virus-transformed rat and goat cells and in chicken cells transformed by viruses rescued from these mammalian cells.
Virology.
1982
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Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity.
Cell.
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Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus.
Proceedings of the National Academy of Sciences of the United States of America.
1980
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Evidence that the src gene product of Rous sarcoma virus is membrane associated.
Virology.
1980
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Localization and characterization of the src-gene product of Rous sarcoma virus.
Cold Spring Harbor symposia on quantitative biology.
1980
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