selected publications
- Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma. Neuro-oncology. 2023 Academic Article GET IT
- PRMT5 Inhibition Drives Therapeutic Vulnerability to Combination Treatment with BCL-2 Inhibition in Mantle Cell Lymphoma. Blood advances. 2023 Academic Article GET IT
- How I read an article that uses machine learning methods. Blood advances. 2023 Academic Article GET IT
- PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma. Blood. 2023 Academic Article GET IT
- The Immunogenomic Landscape of Neuroendocrine Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
- Genetic Risk Factors for End-Stage Hip Osteoarthritis Treated With Total Hip Arthroplasty: A Genome-wide Association Study. The Journal of arthroplasty. 2023 Academic Article GET IT
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Multicenter phase 2 study of oral azacitidine (CC-486) plus CHOP as initial treatment for PTCL.
Blood.
2023
Academic Article
GET IT
Times cited: 5 - Metasurface-enhanced infrared spectroscopy in multiwell format for real-time assaying of live cells. Lab on a chip. 2023 Academic Article GET IT
-
A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine.
2023
Academic Article
GET IT
Times cited: 1 - Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells. Blood cancer discovery. 2023 Academic Article GET IT
- Multi-omic molecular profiling and network biology for precision anaesthesiology: a narrative review. British journal of anaesthesia. 2023 Review GET IT
- Soluble adenylyl cyclase contributes to imiquimod-mediated inflammation and is a potential therapeutic target in psoriasis. Experimental dermatology. 2023 Academic Article GET IT
- Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer. Nature cancer. 2023 Academic Article GET IT
-
Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas.
Nature materials.
2023
Academic Article
GET IT
Times cited: 4 - Identification of Novel Genetic Markers for the Risk of Spinal Pathologies: A Genome-Wide Association Study of 2 Biobanks. The Journal of bone and joint surgery. American volume. 2023 Academic Article GET IT
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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma.
Cell reports.
2023
Academic Article
GET IT
Times cited: 1 -
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2.
Science translational medicine.
2023
Academic Article
GET IT
Times cited: 2 -
The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.
Cancer research.
2023
Academic Article
GET IT
Times cited: 3 - Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism. bioRxiv : the preprint server for biology. 2023 Article GET IT
-
Endothelial cell-leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities.
Blood.
2023
Academic Article
GET IT
Times cited: 1 -
Wearable sensor-based performance status assessment in cancer: A pilot multicenter study from the Alliance for Clinical Trials in Oncology (A19_Pilot2).
PLOS digital health.
2023
Academic Article
GET IT
Times cited: 13 - BTG1 mutation yields supercompetitive B cells primed for malignant transformation. Science (New York, N.Y.). 2023 Academic Article GET IT
-
An atlas of substrate specificities for the human serine/threonine kinome.
Nature.
2023
Academic Article
GET IT
Times cited: 19 - Population-Level Prevalence of Rare Variants Associated With Atrial Fibrillation and its Impact on Patient Outcomes. JACC. Clinical electrophysiology. 2023 Academic Article GET IT
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Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer.
Nature communications.
2023
Academic Article
GET IT
Times cited: 2 -
A non-invasive artificial intelligence approach for the prediction of human blastocyst ploidy: a retrospective model development and validation study.
The Lancet. Digital health.
2023
Academic Article
GET IT
Times cited: 2 - Whole-genome characterization of myoepithelial carcinomas of the soft tissue. Cold Spring Harbor molecular case studies. 2022 Academic Article GET IT
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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
The Journal of clinical investigation.
2022
Academic Article
GET IT
Times cited: 1 -
Application of Deep Learning on Single-cell RNA Sequencing Data Analysis: A Review.
Genomics, proteomics & bioinformatics.
2022
Review
GET IT
Times cited: 1 -
Spatial omics technologies at multimodal and single cell/subcellular level.
Genome biology.
2022
Review
GET IT
Times cited: 3 -
Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration.
JCI insight.
2022
Academic Article
GET IT
Times cited: 1 - Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging. Nature methods. 2022 Article GET IT
- Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology. 2022 Review GET IT
-
Persistent alveolar type 2 dysfunction and lung structural derangement in post-acute COVID-19.
medRxiv : the preprint server for health sciences.
2022
Article
GET IT
Times cited: 1074 - Predicting inpatient mortality in patients with inflammatory bowel disease: A machine learning approach. Journal of gastroenterology and hepatology. 2022 Academic Article GET IT
- Tumor-Infiltrating Myeloid Cells Confer De Novo Resistance to PD-L1 Blockade through EMT-Stromal and Tgfβ-Dependent Mechanisms. Molecular cancer therapeutics. 2022 Academic Article GET IT
-
African Ancestry-Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent.
Cancer discovery.
2022
Academic Article
GET IT
Times cited: 7 -
Genome-Wide Association Study of Adhesive Capsulitis Suggests Significant Genetic Risk Factors.
The Journal of bone and joint surgery. American volume.
2022
Academic Article
GET IT
Times cited: 1 -
Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment.
2022
GET IT
Times cited: 1975 -
Unsupervised discovery of tissue architecture in multiplexed imaging.
Nature methods.
2022
Academic Article
GET IT
Times cited: 3 -
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
Science signaling.
2022
Academic Article
GET IT
Times cited: 8 -
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation.
Cell reports.
2022
Academic Article
GET IT
Times cited: 1 -
Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.
Science immunology.
2022
Academic Article
GET IT
Times cited: 5 - Gain of Chromosome 1q Perturbs a Competitive Endogenous RNA Network to Promote Melanoma Metastasis. Cancer research. 2022 Academic Article GET IT
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A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2022
Academic Article
GET IT
Times cited: 4 - GA4GH Phenopackets: A Practical Introduction. Advanced genetics (Hoboken, N.J.). 2022 Academic Article GET IT
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Characterization of Genetic Risk of End-Stage Knee Osteoarthritis Treated with Total Knee Arthroplasty: A Genome-Wide Association Study.
The Journal of bone and joint surgery. American volume.
2022
Academic Article
GET IT
Times cited: 2 -
GLI1 -Rearranged Enteric Tumor : Expanding the Spectrum of Gastrointestinal Neoplasms With GLI1 Gene Fusions.
The American journal of surgical pathology.
2022
Academic Article
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Times cited: 1 -
Next generation patient derived tumor organoids.
Translational research : the journal of laboratory and clinical medicine.
2022
Review
GET IT
Times cited: 1 - Nicotinamide drives T cell activation in the mammary tumor microenvironment. Journal of translational medicine. 2022 Letter GET IT
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The GA4GH Phenopacket schema defines a computable representation of clinical data.
Nature biotechnology.
2022
Letter
GET IT
Times cited: 13 -
Weakly-supervised tumor purity prediction from frozen H&E stained slides.
EBioMedicine.
2022
Academic Article
GET IT
Times cited: 3 -
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.
The Journal of experimental medicine.
2022
Academic Article
GET IT
Times cited: 3 -
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations.
Current opinion in genetics & development.
2022
Review
GET IT
Times cited: 2 -
The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62.
Cell reports.
2022
Academic Article
GET IT
Times cited: 12 -
An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes.
Cancer cell.
2022
Academic Article
GET IT
Times cited: 9 -
Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.
The Journal of experimental medicine.
2022
Academic Article
GET IT
Times cited: 3 - Characterization of GECPAR, a noncoding RNA that regulates the transcriptional program of diffuse large B-cell lymphoma. Haematologica. 2022 Academic Article GET IT
-
Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab.
2022
GET IT
Times cited: 3 -
Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy.
iScience.
2022
Academic Article
GET IT
Times cited: 19 -
Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma.
Cell reports.
2022
Academic Article
GET IT
Times cited: 7 -
The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.
Molecular oncology.
2022
Academic Article
GET IT
Times cited: 4 -
Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound.
European urology.
2022
Academic Article
GET IT
Times cited: 5 -
Utility of multimodality molecular profiling for pediatric patients with central nervous system tumors.
Neuro-oncology advances.
2022
Academic Article
GET IT
Times cited: 100 -
Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2022
Academic Article
GET IT
Times cited: 13 -
RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.
Annals of surgical oncology.
2022
Academic Article
GET IT
Times cited: 243 -
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.
JCI insight.
2022
Academic Article
GET IT
Times cited: 3 -
Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms.
Frontiers in cell and developmental biology.
2022
Academic Article
GET IT
Times cited: 62 -
Automatic classification of informative laryngoscopic images using deep learning.
Laryngoscope investigative otolaryngology.
2022
Academic Article
GET IT
Times cited: 75 - Simple Linear Cancer Risk Prediction Models With Novel Features Outperform Complex Approaches. JCO clinical cancer informatics. 2022 Academic Article GET IT
-
System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
Cell reports. Medicine.
2022
Academic Article
GET IT
Times cited: 13 -
Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.
British journal of cancer.
2022
Academic Article
GET IT
Times cited: 6 -
Metabolic and Immune Markers for Precise Monitoring of COVID-19 Severity and Treatment.
Frontiers in immunology.
2022
Academic Article
GET IT
Times cited: 9 -
GCN2 kinase activation by ATP-competitive kinase inhibitors.
Nature chemical biology.
2021
Academic Article
GET IT
Times cited: 9 -
Systems biology analysis of human genomes points to key pathways conferring spina bifida risk.
Proceedings of the National Academy of Sciences of the United States of America.
2021
Academic Article
GET IT
Times cited: 5 -
Pan-cancer analysis reveals molecular patterns associated with age.
Cell reports.
2021
Academic Article
GET IT
Times cited: 9 -
Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation.
Cell reports.
2021
Academic Article
GET IT
Times cited: 4 - Publisher Correction: Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank. Scientific reports. 2021 Article GET IT
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Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors.
Advanced materials (Deerfield Beach, Fla.).
2021
Academic Article
GET IT
Times cited: 16 -
Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer.
Cell systems.
2021
Academic Article
GET IT
Times cited: 4 -
Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank.
Scientific reports.
2021
Academic Article
GET IT
Times cited: 5 -
Blood biomarkers reflect the effects of obesity and inflammation on the human breast transcriptome.
Carcinogenesis.
2021
Academic Article
GET IT
Times cited: 3 -
CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement.
Developmental cell.
2021
Academic Article
GET IT
Times cited: 4 - Correction: Discovery and clinical introduction of first-in-class imipridone ONC201. Oncotarget. 2021 Article GET IT
-
Author Correction: A molecular single-cell lung atlas of lethal COVID-19.
Nature.
2021
Article
GET IT
Times cited: 2 - Dissecting bulk transcriptomes of diffuse large B cell lymphoma. Cancer cell. 2021 Comment GET IT
-
RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma.
Journal of personalized medicine.
2021
Academic Article
GET IT
Times cited: 43 -
OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity.
Nature immunology.
2021
Academic Article
GET IT
Times cited: 4 -
Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes.
Frontiers in immunology.
2021
Academic Article
GET IT
Times cited: 2 -
Artificial intelligence in cancer research, diagnosis and therapy.
Nature reviews. Cancer.
2021
Academic Article
GET IT
Times cited: 43 -
The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.
Journal of virology.
2021
Academic Article
GET IT
Times cited: 32 -
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Nature communications.
2021
Academic Article
GET IT
Times cited: 12 -
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.
Cell reports.
2021
Academic Article
GET IT
Times cited: 9 -
Correction to: The role of machine learning in clinical research: transforming the future of evidence generation.
Trials.
2021
Article
GET IT
Times cited: 2 -
Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.
2021
Academic Article
GET IT
Times cited: 2 -
The role of machine learning in clinical research: transforming the future of evidence generation.
Trials.
2021
Letter
GET IT
Times cited: 40 -
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.
NPJ genomic medicine.
2021
Academic Article
GET IT
Times cited: 52892 -
A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.
American journal of human genetics.
2021
Academic Article
GET IT
Times cited: 2 -
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing.
The oncologist.
2021
Academic Article
GET IT
Times cited: 6 -
Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology.
Seminars in cancer biology.
2021
Review
GET IT
Times cited: 3 -
Diet-regulated production of PDGFcc by macrophages controls energy storage.
Science (New York, N.Y.).
2021
Academic Article
GET IT
Times cited: 43 -
Clinical utility of whole-genome sequencing in precision oncology.
Seminars in cancer biology.
2021
Review
GET IT
Times cited: 17 -
Analytical demands to use whole-genome sequencing in precision oncology.
Seminars in cancer biology.
2021
Review
GET IT
Times cited: 9 -
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Nature communications.
2021
Academic Article
GET IT
Times cited: 21 -
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
NPJ precision oncology.
2021
Academic Article
GET IT
Times cited: 224 -
Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial.
The Lancet. Oncology.
2021
Academic Article
GET IT
Times cited: 126 -
Discovery of Candidate DNA Methylation Cancer Driver Genes.
Cancer discovery.
2021
Academic Article
GET IT
Times cited: 26 -
Incorporating cytologic adequacy assessment into precision oncology workflow using telepathology: An institutional experience.
Cancer cytopathology.
2021
Academic Article
GET IT
Times cited: 1 -
A molecular single-cell lung atlas of lethal COVID-19.
Nature.
2021
Academic Article
GET IT
Times cited: 196 -
Artificial intelligence in oncology: From bench to clinic.
Seminars in cancer biology.
2021
Review
GET IT
Times cited: 8 -
QSER1 protects DNA methylation valleys from de novo methylation.
Science (New York, N.Y.).
2021
Academic Article
GET IT
Times cited: 39 - Social and Clinical Determinants of COVID-19 Outcomes: Modeling Real-World Data from a Pandemic Epicenter. medRxiv : the preprint server for health sciences. 2021 Article GET IT
-
RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.
Leukemia.
2021
Academic Article
GET IT
Times cited: 21 -
The road from Rous sarcoma virus to precision medicine.
The Journal of experimental medicine.
2021
Academic Article
GET IT
Times cited: 1 -
Deep learning predicts chromosomal instability from histopathology images.
iScience.
2021
Academic Article
GET IT
Times cited: 10 -
Artificial Intelligence in Cancer Research and Precision Medicine.
Cancer discovery.
2021
Review
GET IT
Times cited: 93 -
The spatial landscape of lung pathology during COVID-19 progression.
Nature.
2021
Academic Article
GET IT
Times cited: 145 -
Towards artificial intelligence-driven pathology assessment for hematological malignancies.
Blood cancer discovery.
2021
Academic Article
GET IT
Times cited: 2 -
A Deep Learning Approach to Diagnostic Classification of Prostate Cancer Using Pathology-Radiology Fusion.
Journal of magnetic resonance imaging : JMRI.
2021
Academic Article
GET IT
Times cited: 21 - Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps. bioRxiv : the preprint server for biology. 2021 Article GET IT
-
Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida.
Genetics in medicine : official journal of the American College of Medical Genetics.
2021
Academic Article
GET IT
Times cited: 5 -
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway.
Cell reports.
2021
Article
GET IT
Times cited: 4 -
Building biorepositories in the midst of a pandemic.
Journal of clinical and translational science.
2021
Academic Article
GET IT
Times cited: 160 -
Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway.
Cell reports.
2021
Academic Article
GET IT
Times cited: 11 -
Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.
Cancer research.
2021
Academic Article
GET IT
Times cited: 40 -
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.
Nature chemical biology.
2021
Academic Article
GET IT
Times cited: 6 -
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology.
2021
Academic Article
GET IT
Times cited: 17 -
Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.
Cancer discovery.
2020
Academic Article
GET IT
Times cited: 77 -
Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression.
Life science alliance.
2020
Academic Article
GET IT
Times cited: 34 - The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro. bioRxiv : the preprint server for biology. 2020 Article GET IT
-
Leveraging phenotypic variability to identify genetic interactions in human phenotypes.
American journal of human genetics.
2020
Academic Article
GET IT
Times cited: 18 -
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Nature.
2020
Academic Article
GET IT
Times cited: 95 -
Common germline-somatic variant interactions in advanced urothelial cancer.
Nature communications.
2020
Academic Article
GET IT
Times cited: 13 -
Performance Characteristics of a Targeted Sequencing Platform for Simultaneous Detection of Single Nucleotide Variants, Insertions/Deletions, Copy Number Alterations, and Gene Fusions in Cancer Genome.
Archives of pathology & laboratory medicine.
2020
Academic Article
GET IT
Times cited: 4 -
High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging.
Proceedings of the National Academy of Sciences of the United States of America.
2020
Academic Article
GET IT
Times cited: 23 -
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage.
Molecular cell.
2020
Academic Article
GET IT
Times cited: 15 -
Clinical, regional, and genetic characteristics of Covid-19 patients from UK Biobank.
PloS one.
2020
Academic Article
GET IT
Times cited: 26 -
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Translational oncology.
2020
Academic Article
GET IT
Times cited: 11 -
Precision medicine and artificial intelligence: overview and relevance to reproductive medicine.
Fertility and sterility.
2020
Review
GET IT
Times cited: 14 -
Predictive modeling in reproductive medicine: Where will the future of artificial intelligence research take us?.
Fertility and sterility.
2020
Review
GET IT
Times cited: 21 -
The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection.
medRxiv : the preprint server for health sciences.
2020
Article
GET IT
Times cited: 364 -
Limitations of Detecting Genetic Variants from the RNA Sequencing Data in Tissue and Fine-Needle Aspiration Samples.
Thyroid : official journal of the American Thyroid Association.
2020
Academic Article
GET IT
Times cited: 12 -
Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
Cell.
2020
Academic Article
GET IT
Times cited: 80 - Publisher Correction: Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer. Nature communications. 2020 Academic Article GET IT
-
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.
Nature.
2020
Academic Article
GET IT
Times cited: 102 - Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression. medRxiv : the preprint server for health sciences. 2020 Article GET IT
-
The future of precision medicine: towards a more predictive personalized medicine.
Emerging topics in life sciences.
2020
Review
GET IT
Times cited: 17 -
Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma.
Leukemia.
2020
Letter
GET IT
Times cited: 6 -
A machine learning and network framework to discover new indications for small molecules.
PLoS computational biology.
2020
Academic Article
GET IT
Times cited: 8 -
Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma.
Scientific reports.
2020
Academic Article
GET IT
Times cited: 3 -
Building an international consortium for tracking coronavirus health status.
Nature medicine.
2020
Academic Article
GET IT
Times cited: 18 -
Molecular Profiles of Mixed Endometrial Carcinoma.
The American journal of surgical pathology.
2020
Academic Article
GET IT
Times cited: 8 - Publisher Correction: Building an international consortium for tracking coronavirus health status. Nature medicine. 2020 Academic Article GET IT
-
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.
Nature communications.
2020
Academic Article
GET IT
Times cited: 58 -
Urinary Cell Transcriptome Profiling and Identification of ITM2A, SLAMF6, and IKZF3 as Biomarkers of Acute Rejection in Human Kidney Allografts.
Transplantation direct.
2020
Academic Article
GET IT
Times cited: 3 -
Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020
Academic Article
GET IT
Times cited: 6 -
A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations.
Skeletal muscle.
2020
Academic Article
GET IT
Times cited: 70 -
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
Cell.
2020
Academic Article
GET IT
Times cited: 40 -
Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis.
Cells.
2020
Academic Article
GET IT
Times cited: 21 -
Lineage Reversion Drives WNT Independence in Intestinal Cancer.
Cancer discovery.
2020
Academic Article
GET IT
Times cited: 29 -
The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer.
Cancer discovery.
2020
Academic Article
GET IT
Times cited: 20 -
Fusions involving BCOR and CREBBP are rare events in infiltrating glioma.
Acta neuropathologica communications.
2020
Academic Article
GET IT
Times cited: 9 -
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid.
The Journal of experimental medicine.
2020
Academic Article
GET IT
Times cited: 33 -
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy.
Blood.
2020
Academic Article
GET IT
Times cited: 31 -
Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers.
Nature communications.
2020
Academic Article
GET IT
Times cited: 29 -
Graph convolutional networks for computational drug development and discovery.
Briefings in bioinformatics.
2020
Academic Article
GET IT
Times cited: 158 -
A novel prognostic two-gene signature for triple negative breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2020
Academic Article
GET IT
Times cited: 19 -
Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations.
Cancers.
2020
Academic Article
GET IT
Times cited: 265 -
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.
Cancer cell.
2020
Academic Article
GET IT
Times cited: 70 -
CIC is a critical regulator of neuronal differentiation.
JCI insight.
2020
Academic Article
GET IT
Times cited: 15 -
Clinical and Genetic Characteristics of Covid-19 Patients from UK Biobank.
medRxiv : the preprint server for health sciences.
2020
Article
GET IT
Times cited: 480 -
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.
Nature communications.
2020
Academic Article
GET IT
Times cited: 18 -
ABEMUS: platform-specific and data-informed detection of somatic SNVs in cfDNA.
Bioinformatics (Oxford, England).
2020
Academic Article
GET IT
Times cited: 5 -
Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2020
Academic Article
GET IT
Times cited: 12 -
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.
Nature communications.
2020
Academic Article
GET IT
Times cited: 20 -
Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas.
Cancer discovery.
2020
Academic Article
GET IT
Times cited: 74 -
A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.
Nature genetics.
2020
Review
GET IT
Times cited: 66 -
Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer.
The Journal of clinical investigation.
2020
Academic Article
GET IT
Times cited: 88 -
Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration.
Cell reports.
2020
Academic Article
GET IT
Times cited: 126 -
SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy.
Molecular cancer therapeutics.
2020
Academic Article
GET IT
Times cited: 32 -
The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS.
Leukemia.
2020
Academic Article
GET IT
Times cited: 9 -
Urinary cell transcriptomics and acute rejection in human kidney allografts.
JCI insight.
2020
Academic Article
GET IT
Times cited: 19 -
The aging skin microenvironment dictates stem cell behavior.
Proceedings of the National Academy of Sciences of the United States of America.
2020
Academic Article
GET IT
Times cited: 61 -
Computational methods in tumor immunology.
Methods in enzymology.
2020
Academic Article
GET IT
Times cited: 2 -
Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.
Cell reports.
2020
Academic Article
GET IT
Times cited: 51 -
Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2020
Academic Article
GET IT
Times cited: 9 -
A Bayesian machine learning approach for drug target identification using diverse data types.
Nature communications.
2019
Academic Article
GET IT
Times cited: 99 -
Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis.
Cancer research.
2019
Comment
GET IT
Times cited: 50 -
Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery.
Oncoimmunology.
2019
Academic Article
GET IT
Times cited: 43 -
Deep learning-based classification of mesothelioma improves prediction of patient outcome.
Nature medicine.
2019
Academic Article
GET IT
Times cited: 209 -
Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
JCO precision oncology.
2019
Academic Article
GET IT
Times cited: 36 -
Clinical features of neuroendocrine prostate cancer.
European journal of cancer (Oxford, England : 1990).
2019
Academic Article
GET IT
Times cited: 138 -
Exploring tumor clonal evolution in bone marrow of patients with diffuse large B-cell lymphoma by deep IGH sequencing and its potential relevance in relapse.
Blood cancer journal.
2019
Letter
GET IT
Times cited: 2 -
Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution.
JCO precision oncology.
2019
Academic Article
GET IT
Times cited: 105 -
Supplemental estrogen and caloric restriction reduce obesity-induced periprostatic white adipose inflammation in mice.
Carcinogenesis.
2019
Academic Article
GET IT
Times cited: 8 -
Drug knowledge bases and their applications in biomedical informatics research.
Briefings in bioinformatics.
2019
Review
GET IT
Times cited: 23 -
Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.
The American journal of pathology.
2019
Academic Article
GET IT
Times cited: 47 -
Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts.
JCI insight.
2019
Academic Article
GET IT
Times cited: 22 -
Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling.
Nature communications.
2019
Academic Article
GET IT
Times cited: 102 -
The Missing Pieces of Artificial Intelligence in Medicine.
Trends in pharmacological sciences.
2019
Academic Article
GET IT
Times cited: 42 -
Artificial intelligence: its applications in reproductive medicine and the assisted reproductive technologies.
Fertility and sterility.
2019
Editorial Article
GET IT
Times cited: 21 -
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
The Journal of clinical investigation.
2019
Academic Article
GET IT
Times cited: 84 -
Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system.
Genome medicine.
2019
Review
GET IT
Times cited: 131 -
Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia.
Leukemia.
2019
Academic Article
GET IT
Times cited: 28 -
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Cancer cell.
2019
Article
GET IT
Times cited: 17 -
Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression.
Molecular cancer.
2019
Letter
GET IT
Times cited: 28 -
A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.
Cancer discovery.
2019
Academic Article
GET IT
Times cited: 16 -
Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
GET IT
Times cited: 49 -
Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization.
NPJ digital medicine.
2019
Academic Article
GET IT
Times cited: 8 -
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Cancer cell.
2019
Academic Article
GET IT
Times cited: 46 -
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.
Science translational medicine.
2019
Academic Article
GET IT
Times cited: 83 -
Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing.
PLoS genetics.
2019
Academic Article
GET IT
Times cited: 58 -
Oncogenic Addiction to ERBB2 Signaling Predicts Response to Trastuzumab in Urothelial Cancer.
2019
GET IT
Times cited: 4 -
Identification of a therapeutic target using molecular sequencing for treatment of recurrent uterine serous adenocarcinoma.
2019
GET IT
Times cited: 5 -
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.
Nature communications.
2019
Academic Article
GET IT
Times cited: 62 -
Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells.
The Journal of experimental medicine.
2019
Academic Article
GET IT
Times cited: 51 - The application of precision medicine in diagnosing familial Mediterranean fever. Leukemia & lymphoma. 2019 Letter GET IT
-
The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3.
Cancer research.
2019
Academic Article
GET IT
Times cited: 25 -
TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis.
Cell reports.
2019
Academic Article
GET IT
Times cited: 12 -
Predicting peptide presentation by major histocompatibility complex class I: an improved machine learning approach to the immunopeptidome.
BMC bioinformatics.
2019
Academic Article
GET IT
Times cited: 27 -
Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance.
Theranostics.
2019
Academic Article
GET IT
Times cited: 40 -
Drug-Induced Expression-Based Computational Repurposing of Small Molecules Affecting Transcription Factor Activity.
Methods in molecular biology (Clifton, N.J.).
2019
Academic Article
GET IT
Times cited: 2 -
UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors.
Endocrine-related cancer.
2019
Academic Article
GET IT
Times cited: 13 -
Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
GET IT
Times cited: 36 -
Epigenetic analysis identifies factors driving racial disparity in prostate cancer.
Cancer reports (Hoboken, N.J.).
2018
Academic Article
GET IT
Times cited: 6 -
Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.
Nature microbiology.
2018
Academic Article
GET IT
Times cited: 66 -
Association of T-Cell Receptor Repertoire Use With Response to Combined Trastuzumab-Lapatinib Treatment of HER2-Positive Breast Cancer: Secondary Analysis of the NeoALTTO Randomized Clinical Trial.
JAMA oncology.
2018
Academic Article
GET IT
Times cited: 12 -
Prostaglandin E2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.
The Journal of biological chemistry.
2018
Academic Article
GET IT
Times cited: 17 -
CHL1 expression differentiates Hürthle cell carcinoma from benign Hürthle cell nodules.
Journal of surgical oncology.
2018
Academic Article
GET IT
Times cited: 3 -
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery.
2018
Academic Article
GET IT
Times cited: 101 -
Colonoscopic-Guided Pinch Biopsies in Mice as a Useful Model for Evaluating the Roles of Host and Luminal Factors in Colonic Inflammation.
The American journal of pathology.
2018
Academic Article
GET IT
Times cited: 2 -
The Role of Next-Generation Sequencing in Precision Medicine: A Review of Outcomes in Oncology.
Journal of personalized medicine.
2018
Review
GET IT
Times cited: 64 -
Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
GET IT
Times cited: 34 -
Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.
JCI insight.
2018
Academic Article
GET IT
Times cited: 39 -
Patient derived organoids to model rare prostate cancer phenotypes.
Nature communications.
2018
Academic Article
GET IT
Times cited: 203 - CATCH-KB: Establishing a Pharmacogenomics Variant Repository for Chemotherapy-Induced Cardiotoxicity. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. 2018 Academic Article GET IT
-
Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis.
Cancer letters.
2018
Academic Article
GET IT
Times cited: 40 -
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.
The Journal of allergy and clinical immunology.
2018
Academic Article
GET IT
Times cited: 264 -
Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Molecular cell.
2018
Academic Article
GET IT
Times cited: 48 - Author Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells. Nature genetics. 2018 Academic Article GET IT
- Publisher Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells. Nature genetics. 2018 Academic Article GET IT
-
Rapid identification of BCR/ABL1-like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications.
British journal of haematology.
2018
Academic Article
GET IT
Times cited: 33 -
A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease.
Cancer prevention research (Philadelphia, Pa.).
2018
Academic Article
GET IT
Times cited: 13 -
Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms.
Oncoimmunology.
2018
Academic Article
GET IT
Times cited: 11 -
Chromosomal instability drives metastasis through a cytosolic DNA response.
Nature.
2018
Academic Article
GET IT
Times cited: 710 -
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis.
Nature communications.
2018
Academic Article
GET IT
Times cited: 42 -
The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling.
Oncotarget.
2018
Academic Article
GET IT
Times cited: 11 -
Analyzing DNA Methylation Patterns During Tumor Evolution.
Methods in molecular biology (Clifton, N.J.).
2018
Academic Article
GET IT
Times cited: 1 -
Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing.
Methods in molecular biology (Clifton, N.J.).
2018
Review
GET IT
Times cited: 9 -
Deep Convolutional Neural Networks Enable Discrimination of Heterogeneous Digital Pathology Images.
EBioMedicine.
2017
Academic Article
GET IT
Times cited: 190 -
Bone biopsy protocol for advanced prostate cancer in the era of precision medicine.
Cancer.
2017
Academic Article
GET IT
Times cited: 33 -
HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway.
Stem cell reports.
2017
Academic Article
GET IT
Times cited: 41 -
STMN1 is Overexpressed in Adrenocortical Carcinoma and Promotes a More Aggressive Phenotype In Vitro.
Annals of surgical oncology.
2017
Academic Article
GET IT
Times cited: 14 -
Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 48 -
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
Nature genetics.
2017
Academic Article
GET IT
Times cited: 120 -
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.
Nature communications.
2017
Academic Article
GET IT
Times cited: 109 -
Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites.
Nature.
2017
Academic Article
GET IT
Times cited: 124 -
A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.
Cell metabolism.
2017
Academic Article
GET IT
Times cited: 119 -
Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape.
Cell host & microbe.
2017
Academic Article
GET IT
Times cited: 87 -
Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
PloS one.
2017
Academic Article
GET IT
Times cited: 27 -
EthSEQ: ethnicity annotation from whole exome sequencing data.
Bioinformatics (Oxford, England).
2017
Academic Article
GET IT
Times cited: 23 -
R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.
Nature communications.
2017
Academic Article
GET IT
Times cited: 77 -
Inherited determinants of early recurrent somatic mutations in prostate cancer.
Nature communications.
2017
Academic Article
GET IT
Times cited: 22 -
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.
JCO precision oncology.
2017
Academic Article
GET IT
Times cited: 584 -
Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma.
Journal of visualized experiments : JoVE.
2017
Academic Article
GET IT
Times cited: 5 -
Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell.
Nucleic acids research.
2017
Academic Article
GET IT
Times cited: 30 -
Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.
Nature.
2017
Academic Article
GET IT
Times cited: 128 -
Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.
Nature communications.
2017
Academic Article
GET IT
Times cited: 53 -
An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data.
Nature communications.
2017
Academic Article
GET IT
Times cited: 43 -
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
Nature.
2017
Academic Article
GET IT
Times cited: 144 -
Widespread Mitotic Bookmarking by Histone Marks and Transcription Factors in Pluripotent Stem Cells.
Cell reports.
2017
Academic Article
GET IT
Times cited: 78 -
Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.
The Journal of clinical investigation.
2017
Academic Article
GET IT
Times cited: 6 -
The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations.
Journal of the American Medical Informatics Association : JAMIA.
2017
Academic Article
GET IT
Times cited: 72 -
Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.
Cell.
2017
Academic Article
GET IT
Times cited: 195 -
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 84 -
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression.
eLife.
2017
Academic Article
GET IT
Times cited: 42 -
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 589 -
Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 98 -
Towards a better cancer precision medicine: systems biology meets immunotherapy.
Current opinion in systems biology.
2017
Academic Article
GET IT
Times cited: 8 -
BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 34 -
Melanoma genome evolution across species.
BMC genomics.
2017
Academic Article
GET IT
Times cited: 11 -
Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model.
Cancer research.
2017
Academic Article
GET IT
Times cited: 11 -
Regulatory elements in molecular networks.
Wiley interdisciplinary reviews. Systems biology and medicine.
2017
Review
GET IT
Times cited: 14 -
Sox17 drives functional engraftment of endothelium converted from non-vascular cells.
Nature communications.
2017
Academic Article
GET IT
Times cited: 15 -
A Computational Approach for Identifying Synergistic Drug Combinations.
PLoS computational biology.
2017
Academic Article
GET IT
Times cited: 53 - Systematic Discovery of Chromatin-Bound Protein Complexes from ChIP-seq Datasets. Methods in molecular biology (Clifton, N.J.). 2017 Academic Article GET IT
-
Role of RPL39 in Metaplastic Breast Cancer.
Journal of the National Cancer Institute.
2016
Academic Article
GET IT
Times cited: 51 -
Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Cell chemical biology.
2016
Academic Article
GET IT
Times cited: 29 -
Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.
Nature communications.
2016
Academic Article
GET IT
Times cited: 35 -
Reversible methylation of m6Am in the 5' cap controls mRNA stability.
Nature.
2016
Academic Article
GET IT
Times cited: 660 -
Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
GET IT
Times cited: 20 -
Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.
Oncotarget.
2016
Academic Article
GET IT
Times cited: 19 -
Discovery and clinical introduction of first-in-class imipridone ONC201.
Oncotarget.
2016
Review
GET IT
Times cited: 93 -
Clonal evolution of chemotherapy-resistant urothelial carcinoma.
Nature genetics.
2016
Academic Article
GET IT
Times cited: 201 -
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Cancer discovery.
2016
Academic Article
GET IT
Times cited: 181 -
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Cancer cell.
2016
Academic Article
GET IT
Times cited: 327 -
A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.
Cell chemical biology.
2016
Academic Article
GET IT
Times cited: 95 -
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region.
Immunity.
2016
Academic Article
GET IT
Times cited: 89 -
An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer.
Biomolecules.
2016
Academic Article
GET IT
Times cited: 42 -
Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.
Cancer immunology research.
2016
Academic Article
GET IT
Times cited: 104 -
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
Cancer cell.
2016
Academic Article
GET IT
Times cited: 166 -
KLF4: A new player in plasma cell development.
Cell cycle (Georgetown, Tex.).
2016
Comment
GET IT
Times cited: 2 -
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.
The Journal of clinical investigation.
2016
Academic Article
GET IT
Times cited: 110 -
Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq.
Genome medicine.
2016
Academic Article
GET IT
Times cited: 81 -
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
NPJ genomic medicine.
2016
Academic Article
GET IT
Times cited: 58 -
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
The New England journal of medicine.
2016
Academic Article
GET IT
Times cited: 1009 -
A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.
Cell reports.
2016
Academic Article
GET IT
Times cited: 23 -
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.
Nature communications.
2016
Academic Article
GET IT
Times cited: 23 -
Predictive features of ligand-specific signaling through the estrogen receptor.
Molecular systems biology.
2016
Academic Article
GET IT
Times cited: 34 -
Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.
Diabetes.
2016
Academic Article
GET IT
Times cited: 34 -
Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis.
Journal of cell science.
2016
Academic Article
GET IT
Times cited: 25 -
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.
Nature medicine.
2016
Academic Article
GET IT
Times cited: 933 -
Prostate-Specific Membrane Antigen Is a Potential Antiangiogenic Target in Adrenocortical Carcinoma.
The Journal of clinical endocrinology and metabolism.
2016
Academic Article
GET IT
Times cited: 14 - Practical Analysis of Genome Contact Interaction Experiments. Methods in molecular biology (Clifton, N.J.). 2016 Academic Article GET IT
-
VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma.
Journal of visualized experiments : JoVE.
2015
Academic Article
GET IT
Times cited: 13 -
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.
Blood.
2015
Academic Article
GET IT
Times cited: 57 -
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Science (New York, N.Y.).
2015
Academic Article
GET IT
Times cited: 612 -
EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis.
Leukemia.
2015
Academic Article
GET IT
Times cited: 49 -
Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.
Genome medicine.
2015
Academic Article
GET IT
Times cited: 57 -
Prediction of Genetic Interactions Using Machine Learning and Network Properties.
Frontiers in bioengineering and biotechnology.
2015
Review
GET IT
Times cited: 9 -
5' UTR m(6)A Promotes Cap-Independent Translation.
Cell.
2015
Academic Article
GET IT
Times cited: 1138 -
Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis.
Stem cell reports.
2015
Academic Article
GET IT
Times cited: 38 -
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Nature medicine.
2015
Academic Article
GET IT
Times cited: 289 -
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
Cell reports.
2015
Academic Article
GET IT
Times cited: 77 -
Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.
Science translational medicine.
2015
Academic Article
GET IT
Times cited: 200 -
Integrative Clinical Genomics of Advanced Prostate Cancer.
Cell.
2015
Article
GET IT
Times cited: 340 -
Use of RNA sequencing to evaluate rheumatic disease patients.
Arthritis research & therapy.
2015
Review
GET IT
Times cited: 23 -
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
JAMA oncology.
2015
Academic Article
GET IT
Times cited: 216 -
Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.
Cell reports.
2015
Academic Article
GET IT
Times cited: 96 -
Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival.
Nature cell biology.
2015
Academic Article
GET IT
Times cited: 100 -
A primer on precision medicine informatics.
Briefings in bioinformatics.
2015
Review
GET IT
Times cited: 31 -
Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC.
PloS one.
2015
Academic Article
GET IT
Times cited: 16 -
Integrative clinical genomics of advanced prostate cancer.
Cell.
2015
Academic Article
GET IT
Times cited: 2094 -
CCMCL1: a new model of aggressive mantle cell lymphoma.
Blood.
2015
Letter
GET IT
Times cited: 5 -
Epigenomic evolution in diffuse large B-cell lymphomas.
Nature communications.
2015
Academic Article
GET IT
Times cited: 95 -
The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers.
PLoS genetics.
2015
Academic Article
GET IT
Times cited: 23 -
The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.
Cell.
2015
Academic Article
GET IT
Times cited: 250 -
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.
Blood.
2015
Academic Article
GET IT
Times cited: 110 -
Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model.
Cell reports.
2015
Academic Article
GET IT
Times cited: 90 -
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
The Journal of clinical investigation.
2015
Academic Article
GET IT
Times cited: 86 -
ELAVL1 modulates transcriptome-wide miRNA binding in murine macrophages.
Cell reports.
2014
Academic Article
GET IT
Times cited: 47 -
Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells.
Blood.
2014
Academic Article
GET IT
Times cited: 237 -
ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
GET IT
Times cited: 44 -
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.
Nature communications.
2014
Academic Article
GET IT
Times cited: 494 -
Lymphoblastic transformation of follicular lymphoma: a clinicopathologic and molecular analysis of 7 patients.
Human pathology.
2014
Academic Article
GET IT
Times cited: 54 -
Dicer expression and microRNA dysregulation associate with aggressive features in thyroid cancer.
Surgery.
2014
Academic Article
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Times cited: 36 -
Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells.
Nature biotechnology.
2014
Academic Article
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Times cited: 177 -
Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.
Circulation research.
2014
Academic Article
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Times cited: 23 -
Cancer systems biology: embracing complexity to develop better anticancer therapeutic strategies.
Oncogene.
2014
Review
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Times cited: 97 -
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
PLoS genetics.
2014
Academic Article
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Times cited: 155 -
Tracing the roots of cancer evolution.
Cancer discovery.
2014
Comment
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Times cited: 2 -
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.
Genome biology.
2014
Academic Article
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Times cited: 74 -
Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.
Cancer discovery.
2014
Academic Article
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Times cited: 212 -
Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib.
Cancer biology & therapy.
2014
Academic Article
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Times cited: 26 -
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature.
2014
Academic Article
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Times cited: 174 -
DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets.
Nature chemical biology.
2014
Academic Article
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Times cited: 87 -
Silencing of UCHL1 by CpG promoter hyper-methylation is associated with metastatic gastroenteropancreatic well-differentiated neuroendocrine (carcinoid) tumors.
Annals of surgical oncology.
2014
Academic Article
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Times cited: 15 -
Histone variant H3.3 is an essential maternal factor for oocyte reprogramming.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 72 -
Characterization of the human cumulus cell transcriptome during final follicular maturation and ovulation.
Molecular human reproduction.
2014
Academic Article
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Times cited: 59 -
Double-stranded DNA in exosomes: a novel biomarker in cancer detection.
Cell research.
2014
Letter
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Times cited: 1141 -
The transcriptional modulator BCL6 as a molecular target for breast cancer therapy.
Oncogene.
2014
Academic Article
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Times cited: 55 -
Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells.
Stem cells (Dayton, Ohio).
2014
Academic Article
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Times cited: 20 -
Molecular diagnosis of autosomal dominant polycystic kidney disease using next-generation sequencing.
The Journal of molecular diagnostics : JMD.
2013
Academic Article
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Times cited: 51 -
Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
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Times cited: 66 -
EZH2 mutations are frequent and represent an early event in follicular lymphoma.
Blood.
2013
Academic Article
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Times cited: 234 -
Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.
Immunity.
2013
Academic Article
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Times cited: 202 -
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.
Cell reports.
2013
Academic Article
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Times cited: 134 -
Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration.
Developmental cell.
2013
Academic Article
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Times cited: 438 -
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature.
2013
Academic Article
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Times cited: 106 -
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
Nature neuroscience.
2013
Academic Article
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Times cited: 353 -
AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes.
Nature.
2013
Academic Article
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Times cited: 76 -
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.
Cancer cell.
2013
Academic Article
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Times cited: 608 -
A novel approach for characterizing microsatellite instability in cancer cells.
PloS one.
2013
Academic Article
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Times cited: 39 -
Punctuated evolution of prostate cancer genomes.
Cell.
2013
Academic Article
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Times cited: 906 -
Downregulation of FOXP1 is required during germinal center B-cell function.
Blood.
2013
Academic Article
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Times cited: 51 -
Inferring chromatin-bound protein complexes from genome-wide binding assays.
Genome research.
2013
Academic Article
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Times cited: 28 -
Epigenomic alterations in localized and advanced prostate cancer.
Neoplasia (New York, N.Y.).
2013
Academic Article
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Times cited: 61 -
Metabolic alterations in lung cancer-associated fibroblasts correlated with increased glycolytic metabolism of the tumor.
Molecular cancer research : MCR.
2013
Academic Article
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Times cited: 76 -
Porous materials with optimal adsorption thermodynamics and kinetics for CO2 separation.
Nature.
2013
Academic Article
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Times cited: 1782 -
NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche.
Nature.
2013
Academic Article
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Times cited: 118 -
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.
PLoS genetics.
2013
Academic Article
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Times cited: 98 -
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
Cancer research.
2012
Academic Article
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Times cited: 150 -
Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis.
The Journal of biological chemistry.
2012
Academic Article
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Times cited: 63 -
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition.
Blood.
2012
Academic Article
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Times cited: 69 -
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia.
Cancer discovery.
2012
Academic Article
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Times cited: 74 -
Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression.
Cell.
2012
Academic Article
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Times cited: 172 -
Oncogenic transcription factors as master regulators of chromatin topology: a new role for ERG in prostate cancer.
Cell cycle (Georgetown, Tex.).
2012
Academic Article
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Times cited: 11 -
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma.
PloS one.
2012
Academic Article
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Times cited: 41 -
Oncogene-mediated alterations in chromatin conformation.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 110 -
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
Cell.
2012
Academic Article
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Times cited: 2512 -
Calcimimetics versus parathyroidectomy for treatment of primary hyperparathyroidism: retrospective chart analysis of a prospective database.
Annals of surgery.
2012
Academic Article
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Times cited: 30 -
Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease.
PloS one.
2012
Academic Article
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Times cited: 45 -
Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 40 -
A panel of four miRNAs accurately differentiates malignant from benign indeterminate thyroid lesions on fine needle aspiration.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2012
Academic Article
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Times cited: 119 -
Using transcriptome sequencing to identify mechanisms of drug action and resistance.
Nature chemical biology.
2012
Academic Article
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Times cited: 125 -
Faster sequencers, larger datasets, new challenges.
Genome biology.
2012
Academic Article
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Times cited: 32 -
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
Blood.
2011
Academic Article
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Times cited: 114 -
An integrated ChIP-seq analysis platform with customizable workflows.
BMC bioinformatics.
2011
Academic Article
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Times cited: 70 -
Large-scale discovery and characterization of protein regulatory motifs in eukaryotes.
PloS one.
2010
Academic Article
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Times cited: 28 -
Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.
American journal of human genetics.
2010
Academic Article
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Times cited: 73 -
Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite.
PLoS pathogens.
2010
Academic Article
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Times cited: 171 -
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis.
Blood.
2010
Academic Article
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Times cited: 246 -
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma.
Blood.
2010
Academic Article
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Times cited: 121 -
Revealing global regulatory perturbations across human cancers.
Molecular cell.
2009
Academic Article
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Times cited: 148 -
DISPARE: DIScriminative PAttern REfinement for Position Weight Matrices.
BMC bioinformatics.
2009
Academic Article
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Times cited: 6 -
Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition.
Development (Cambridge, England).
2009
Academic Article
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Times cited: 83 -
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.
Blood.
2009
Academic Article
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Times cited: 176 -
let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts.
The Journal of biological chemistry.
2009
Academic Article
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Times cited: 95 -
A universal framework for regulatory element discovery across all genomes and data types.
Molecular cell.
2007
Academic Article
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Times cited: 224 -
Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo.
PLoS biology.
2007
Academic Article
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Times cited: 207 -
Developing a systems-level understanding of gene expression.
Genome biology.
2007
Conference Paper
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Times cited: 2 -
Fastcompare: a nonalignment approach for genome-scale discovery of DNA and mRNA regulatory elements using network-level conservation.
Methods in molecular biology (Clifton, N.J.).
2007
Academic Article
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Times cited: 7 -
Ab initio genotype-phenotype association reveals intrinsic modularity in genetic networks.
Molecular systems biology.
2006
Academic Article
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Times cited: 46 -
Revealing posttranscriptional regulatory elements through network-level conservation.
PLoS computational biology.
2005
Academic Article
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Times cited: 68 -
Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach.
Genome biology.
2005
Academic Article
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Times cited: 106 -
IMGT/PhyloGene: an on-line tool for comparative analysis of immunoglobulin and T cell receptor genes.
Developmental and comparative immunology.
2003
Academic Article
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Times cited: 36 -
Reconstructing the duplication history of tandemly repeated genes.
Molecular biology and evolution.
2002
Academic Article
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Times cited: 61 -
An efficient and accurate distance based algorithm to reconstruct tandem duplication trees.
Bioinformatics (Oxford, England).
2002
Academic Article
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Times cited: 16