selected publications
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Targeted viral adaptation generates a simian-tropic hepatitis B virus that infects marmoset cells.
Nature communications.
2023
Academic Article
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Times cited: 1968 -
Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Nature.
2023
Academic Article
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Times cited: 1 - Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Science advances. 2023 Academic Article GET IT
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A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection.
Nature cell biology.
2023
Academic Article
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Times cited: 413 -
Evaluating sleep in covert encephalopathy with wearable technology: results from the WATCHES study.
Hepatology communications.
2023
Academic Article
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Times cited: 6 - Organelle stress and alterations in interorganelle crosstalk during liver fibrosis. Hepatology (Baltimore, Md.). 2023 Academic Article GET IT
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Persistent alveolar type 2 dysfunction and lung structural derangement in post-acute COVID-19.
medRxiv : the preprint server for health sciences.
2022
Article
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Times cited: 1074 -
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
Science signaling.
2022
Academic Article
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Times cited: 8 - Multiple Facets of Cellular Homeostasis and Regeneration of the Mammalian Liver. Annual review of physiology. 2022 Review GET IT
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Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path.
ACS bio & med chem Au.
2022
Academic Article
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Times cited: 195 -
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Cell stem cell.
2022
Academic Article
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Times cited: 111 -
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery.
Science translational medicine.
2022
Academic Article
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Times cited: 47 -
Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.
Science immunology.
2022
Academic Article
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Times cited: 5 -
SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy.
Pediatric research.
2022
Academic Article
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Times cited: 3 -
Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses.
JHEP reports : innovation in hepatology.
2022
Academic Article
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Times cited: 2 -
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction.
Nature cell biology.
2022
Academic Article
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Times cited: 5 -
A diminished immune response underlies age-related SARS-CoV-2 pathologies.
Cell reports.
2022
Academic Article
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Times cited: 7 -
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Cell.
2022
Letter
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Times cited: 10 -
Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy.
iScience.
2022
Academic Article
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Times cited: 19 -
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.
Cell stem cell.
2022
Academic Article
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Times cited: 12 - Booster vaccines for COVID-19 vaccine breakthrough cases?. Lancet (London, England). 2022 Letter GET IT
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Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry.
eLife.
2022
Academic Article
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Times cited: 19 -
Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection.
JCI insight.
2022
Review
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Times cited: 35 -
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.
Circulation research.
2022
Academic Article
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Times cited: 23 - Human biliary epithelial cells for regenerative medicine. Cell stem cell. 2022 Comment GET IT
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Comments on 'An airway organoid-based screen identifies a role for the HIF1α‒glycolysis axis in SARS-CoV-2 infection'.
Journal of molecular cell biology.
2022
Comment
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Times cited: 1 - Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection. bioRxiv : the preprint server for biology. 2022 Article GET IT
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System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
Cell reports. Medicine.
2022
Academic Article
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Times cited: 13 -
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Cell metabolism.
2021
Article
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Times cited: 11 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease.
Cell reports.
2021
Academic Article
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Times cited: 1 -
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection.
Cell reports.
2021
Academic Article
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Times cited: 26 -
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Stem cell reports.
2021
Article
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Times cited: 3 -
Author Correction: A molecular single-cell lung atlas of lethal COVID-19.
Nature.
2021
Article
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Times cited: 2 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Cell metabolism.
2021
Academic Article
GET IT
Times cited: 86 -
The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.
Journal of virology.
2021
Academic Article
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Times cited: 32 -
Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry.
Molecular medicine (Cambridge, Mass.).
2021
Academic Article
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Times cited: 8 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry. bioRxiv : the preprint server for biology. 2021 Article GET IT
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Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Stem cell reports.
2021
Academic Article
GET IT
Times cited: 26 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- SARS-CoV-2 Infects Syncytiotrophoblast and Activates Inflammatory Responses in the Placenta. bioRxiv : the preprint server for biology. 2021 Article GET IT
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Hepatology Highlights.
Hepatology (Baltimore, Md.).
2021
Academic Article
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Times cited: 1 - SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence. Research square. 2021 Article GET IT
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SARS-CoV-2 infection induces beta cell transdifferentiation.
Cell metabolism.
2021
Academic Article
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Times cited: 90 -
Cell and Tissue Therapy for the Treatment of Chronic Liver Disease.
Annual review of biomedical engineering.
2021
Review
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Times cited: 8 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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A molecular single-cell lung atlas of lethal COVID-19.
Nature.
2021
Academic Article
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Times cited: 196 -
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.
Circulation research.
2021
Academic Article
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Times cited: 25 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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The spatial landscape of lung pathology during COVID-19 progression.
Nature.
2021
Academic Article
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Times cited: 145 - Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance. medRxiv : the preprint server for health sciences. 2021 Article GET IT
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Peptide-based scaffolds for the culture and maintenance of primary human hepatocytes.
Scientific reports.
2021
Academic Article
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Times cited: 14 -
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.
Nature communications.
2021
Academic Article
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Times cited: 67 - Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps. bioRxiv : the preprint server for biology. 2021 Article GET IT
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Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms.
Gastroenterology.
2021
Academic Article
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Times cited: 80 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis.
JHEP reports : innovation in hepatology.
2021
Academic Article
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Times cited: 1 -
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
Journal of leukocyte biology.
2021
Academic Article
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Times cited: 55 -
Evolution of antibody immunity to SARS-CoV-2.
Nature.
2021
Academic Article
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Times cited: 881 - Evolution of Antibody Immunity to SARS-CoV-2. bioRxiv : the preprint server for biology. 2021 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro. bioRxiv : the preprint server for biology. 2020 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
- SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2. Research square. 2020 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Nature.
2020
Academic Article
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Times cited: 274 -
The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection.
medRxiv : the preprint server for health sciences.
2020
Article
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Times cited: 364 -
An Adhesive Hydrogel with "Load-Sharing" Effect as Tissue Bandages for Drug and Cell Delivery.
Advanced materials (Deerfield Beach, Fla.).
2020
Academic Article
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Times cited: 89 - Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2. Research square. 2020 Article GET IT
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Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.
Nature.
2020
Academic Article
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Times cited: 102 -
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell.
2020
Academic Article
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Times cited: 477 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
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A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Cell stem cell.
2020
Academic Article
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Times cited: 420 -
Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy.
Journal of medical virology.
2020
Letter
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Times cited: 103 -
Targeting potential drivers of COVID-19: Neutrophil extracellular traps.
The Journal of experimental medicine.
2020
Academic Article
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Times cited: 31 -
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Cell.
2020
Academic Article
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Times cited: 2523 -
Gastrointestinal and Hepatic Manifestations of 2019 Novel Coronavirus Disease in a Large Cohort of Infected Patients From New York: Clinical Implications.
Gastroenterology.
2020
Academic Article
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Times cited: 95 -
Long-term in vivo biocompatibility of single-walled carbon nanotubes.
PloS one.
2020
Academic Article
GET IT
Times cited: 34 - Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids. bioRxiv : the preprint server for biology. 2020 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
- Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions. bioRxiv : the preprint server for biology. 2020 Article GET IT
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SARS-COV-2 infection (coronavirus disease 2019) for the gastrointestinal consultant.
World journal of gastroenterology.
2020
Review
GET IT
Times cited: 40 -
Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells.
Gastroenterology.
2020
Academic Article
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Times cited: 20 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
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Banning carbon nanotubes would be scientifically unjustified and damaging to innovation.
Nature nanotechnology.
2020
Letter
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Times cited: 53 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
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Conservation of cell-intrinsic immune responses in diverse nonhuman primate species.
Life science alliance.
2019
Academic Article
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Times cited: 3 -
Engineering transferrable microvascular meshes for subcutaneous islet transplantation.
Nature communications.
2019
Academic Article
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Times cited: 41 -
Targeting Hepatitis B Virus Covalently Closed Circular DNA and Hepatitis B Virus X Protein: Recent Advances and New Approaches.
ACS infectious diseases.
2019
Academic Article
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Times cited: 11 -
Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells.
Nature communications.
2019
Academic Article
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Times cited: 20 -
Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma.
Cancer research.
2019
Academic Article
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Times cited: 78 -
Analysis of Host Responses to Hepatitis B and Delta Viral Infections in a Micro-scalable Hepatic Co-culture System.
Hepatology (Baltimore, Md.).
2019
Academic Article
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Times cited: 23 -
Hepatology Highlights.
Hepatology (Baltimore, Md.).
2019
Academic Article
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Times cited: 1 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
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An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo.
Science translational medicine.
2018
Academic Article
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Times cited: 55 -
Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.
Science translational medicine.
2018
Academic Article
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Times cited: 32 -
Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery.
Journal of visualized experiments : JoVE.
2018
Academic Article
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Times cited: 12 -
Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription.
mBio.
2018
Academic Article
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Times cited: 25 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2018 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2018 Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2018 Article GET IT
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Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Nature cell biology.
2018
Academic Article
GET IT
Times cited: 887 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2018 Editorial Article GET IT
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Hepatitis E virus: advances and challenges.
Nature reviews. Gastroenterology & hepatology.
2017
Review
GET IT
Times cited: 161 -
Scalable Production and Cryostorage of Organoids Using Core-Shell Decoupled Hydrogel Capsules.
Advanced biosystems.
2017
Academic Article
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Times cited: 825 -
Nicotinamide N-methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes.
Hepatology communications.
2017
Academic Article
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Times cited: 4 -
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.
Cell stem cell.
2017
Academic Article
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Times cited: 162 -
Endoscopic Sleeve Gastroplasty Significantly Reduces Body Mass Index and Metabolic Complications in Obese Patients.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2016
Academic Article
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Times cited: 140 -
Hepatocarcinogenesis associated with hepatitis B, delta and C viruses.
Current opinion in virology.
2016
Review
GET IT
Times cited: 37 -
Pluripotent Stem Cell-Derived Hepatocyte-like Cells: A Tool to Study Infectious Disease.
Current pathobiology reports.
2016
Academic Article
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Times cited: 11 -
Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies.
Virology.
2016
Academic Article
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Times cited: 13 -
Engraftment of human induced pluripotent stem cell-derived hepatocytes in immunocompetent mice via 3D co-aggregation and encapsulation.
Scientific reports.
2015
Academic Article
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Times cited: 67 -
A cell culture system for distinguishing hepatitis C viruses with and without liver cancer-related mutations in the viral core gene.
Journal of hepatology.
2015
Academic Article
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Times cited: 19 -
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus.
Scientific reports.
2015
Academic Article
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Times cited: 225 -
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nature cell biology.
2015
Academic Article
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Times cited: 1775 -
Microbial-derived lithocholic acid and vitamin K2 drive the metabolic maturation of pluripotent stem cells-derived and fetal hepatocytes.
Hepatology (Baltimore, Md.).
2015
Academic Article
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Times cited: 66 -
Patterning vascular networks in vivo for tissue engineering applications.
Tissue engineering. Part C, Methods.
2015
Academic Article
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Times cited: 43 -
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.
Stem cell reports.
2015
Academic Article
GET IT
Times cited: 97 -
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 196 -
Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.
Tissue engineering. Part A.
2014
Academic Article
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Times cited: 100 -
Pluripotent stem cell-derived hepatocyte-like cells.
Biotechnology advances.
2014
Review
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Times cited: 211 -
Discovery and development of first in class antifungal caspofungin (CANCIDAS®)--a case study.
Natural product reports.
2014
Review
GET IT
Times cited: 101 -
Identification of small molecules for human hepatocyte expansion and iPS differentiation.
Nature chemical biology.
2013
Academic Article
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Times cited: 207 -
InVERT molding for scalable control of tissue microarchitecture.
Nature communications.
2013
Academic Article
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Times cited: 99 -
Modeling hepatitis C virus infection using human induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 190 -
Esophageal stem cells and 3D-cell culture models.
Annals of the New York Academy of Sciences.
2011
Academic Article
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Times cited: 5 -
Humanized mice with ectopic artificial liver tissues.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
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Times cited: 135 -
Hepatic stem cells.
Methods in molecular biology (Clifton, N.J.).
2010
Review
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Times cited: 12 -
Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
2008
Academic Article
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Times cited: 39 -
Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro.
Tissue engineering.
2006
Academic Article
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Times cited: 68 -
Defined conditions for development of functional hepatic cells from human embryonic stem cells.
Stem cells and development.
2005
Academic Article
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Times cited: 117 -
Laser-guided direct writing for three-dimensional tissue engineering.
Biotechnology and bioengineering.
2005
Academic Article
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Times cited: 228 -
Unexpected potential of adult stem cells.
Annals of the New York Academy of Sciences.
2003
Review
GET IT
Times cited: 81 -
Morphine stimulates angiogenesis by activating proangiogenic and survival-promoting signaling and promotes breast tumor growth.
Cancer research.
2002
Academic Article
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Times cited: 492 -
Pluripotency of mesenchymal stem cells derived from adult marrow.
Nature.
2002
Academic Article
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Times cited: 5224 -
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells.
The Journal of clinical investigation.
2002
Academic Article
GET IT
Times cited: 1129 -
Arthroscopically assisted reconstruction of the anterior cruciate ligament: initial clinical experience and minimal 2-year follow-up comparing endoscopic transtibial and two-incision techniques.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.
1997
Academic Article
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Times cited: 49