Biochimica et biophysica acta

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Acylation of lysine residues in human plasma high density lipoprotein increases stability and plasma clearance in vivo.. 1861. 2016
MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition.. 1861. 2016
Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart.. 1857. 2016
Computational approaches to detect allosteric pathways in transmembrane molecular machines.. 1858. 2016
Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.. 1861. 2015
Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis.. 1851. 2015
Equilibrative nucleoside transporter 3 depletion in β-cells impairs mitochondrial function and promotes apoptosis: Relationship to pigmented hypertrichotic dermatosis with insulin-dependent diabetes.. 1852. 2015
miR-204 mediates post-transcriptional down-regulation of PHOX2B gene expression in neuroblastoma cells.. 1849. 2015
Effect of monovalent cations on the kinetics of hypoxic conformational change of mitochondrial complex I.. 1847. 2015
Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells.. 1852. 2015
A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain.. 1848. 2015
The giardial ENTH protein participates in lysosomal protein trafficking and endocytosis.. 1853. 2015
Astaxanthin prevents TGFβ1-induced pro-fibrogenic gene expression by inhibiting Smad3 activation in hepatic stellate cells.. 1850. 2014
Loss of calreticulin function decreases NFκB activity by stabilizing IκB protein.. 1843. 2014
PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2.. 1842. 2014
Histone hypoacetylation-activated genes are repressed by acetyl-CoA- and chromatin-mediated mechanism.. 1839. 2014
SUMOylation and deimination of proteins: two epigenetic modifications involved in Giardia encystation.. 1843. 2014
The architecture of Rhodobacter sphaeroides chromatophores.. 1837. 2014
ND3, ND1 and 39kDa subunits are more exposed in the de-active form of bovine mitochondrial complex I.. 1837. 2014
ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer.. 1838. 2014
Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.. 1833. 2013
Barth syndrome: cellular compensation of mitochondrial dysfunction and apoptosis inhibition due to changes in cardiolipin remodeling linked to tafazzin (TAZ) gene mutation.. 1832. 2013
Overexpression of human Argonaute2 inhibits cell and tumor growth.. 1830. 2013
A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity.. 1833. 2012
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein.. 1818. 2012
The type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.. 1813. 2010
Computational study of drug binding to the membrane-bound tetrameric M2 peptide bundle from influenza A virus.. 1808. 2010
Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha).. 1801. 2010
Chemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors.. 1791. 2009
Apolipoproteins A-I, A-II and E are independently distributed among intracellular and newly secreted HDL of human hepatoma cells.. 1791. 2009
Characteristics of mutants designed to incorporate a new ion pair into the structure of a cold adapted subtilisin-like serine proteinase.. 1794. 2008
Stable Argonaute2 overexpression differentially regulates microRNA production.. 1789. 2008
Calreticulin regulates insulin receptor expression and its downstream PI3 Kinase/Akt signalling pathway.. 1783. 2008
The antimicrobial peptide gramicidin S permeabilizes phospholipid bilayer membranes without forming discrete ion channels.. 1778. 2008
Cholesterol is a determinant of the structures of discoidal high density lipoproteins formed by the solubilization of phospholipid membranes by apolipoprotein A-I.. 1781. 2008
Enhanced ubiquitin-proteasome activity in calreticulin deficient cells: a compensatory mechanism for cell survival.. 1783. 2008
Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease.. 1782. 2007
Bombesin attenuates pre-mRNA splicing of glucocorticoid receptor by regulating the expression of serine-arginine protein p30c (SRp30c) in prostate cancer cells.. 1773. 2007
Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse.. 1770. 2007
The proton pumping stoichiometry of purified mitochondrial complex I reconstituted into proteoliposomes.. 1757. 2006
Fourier transform infrared imaging spectroscopy investigations in the pathogenesis and repair of cartilage.. 1758. 2006
NMR mapping of copper binding sites in alpha-synuclein.. 1764. 2005
Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes.. 1710. 2005
Suppression of macrophage responses to bacterial lipopolysaccharide (LPS) by secretory leukocyte protease inhibitor (SLPI) is independent of its anti-protease function.. 1745. 2005
Comparative kinetic analysis reveals that inducer-specific ion release precedes the mitochondrial permeability transition.. 1708. 2005
Unique ligation properties of eukaryotic NAD+-dependent DNA ligase from Melanoplus sanguinipes entomopoxvirus.. 1701. 2004
Human phosphatidylcholine transfer protein: purification, crystallization and preliminary X-ray diffraction data.. 1596. 2002
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme.. 1586. 2002
Effects of high-density lipoprotein(2) on cholesterol transport and acyl-coenzyme A:cholesterol acyltransferase activity in P388D1 macrophages.. 1530. 2001
Posttranslational processing and differential glycosylation of Tractin, an Ig-superfamily member involved in regulation of axonal outgrowth.. 1479. 2000
A calcium-inhibited Drosophila adenylyl cyclase.. 1495. 2000
Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein.. 1447. 1999
Suppression of macrophage responses to bacterial lipopolysaccharide by a non-secretory form of secretory leukocyte protease inhibitor.. 1451. 1999
Isoforms of the human PDZ-73 protein exhibit differential tissue expression.. 1445. 1999
Mechanism of action of probucol on cholesteryl ester transfer protein (CETP) mRNA in a Chinese hamster ovary cell line that had been stably transfected with a human CETP gene.. 1393. 1998
Regulation of pyruvate dehydrogenase activity and glucose metabolism in post-ischaemic myocardium.. 1406. 1998
Purification, catalytic properties and thermostability of 3-isopropylmalate dehydrogenase from Escherichia coli.. 1337. 1997
A cDNA encoding a putative 37 kDa leucine-rich repeat (LRR) protein, p37NB, isolated from S-type neuroblastoma cell has a differential tissue distribution.. 1309. 1996
Efficient and specific amplification of identified partial duplications of human mitochondrial DNA by long PCR.. 1308. 1996
Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung.. 1264. 1995
Plasma factors affecting the in vitro conversion of high-density lipoproteins labeled with a non-transferable marker.. 1254. 1995
Blue form of bacteriorhodopsin and its order-disorder transition during dehydration.. 1185. 1994
Retinoic acid stimulates the protein kinase C pathway before activation of its beta-nuclear receptor during human teratocarcinoma differentiation.. 1179. 1993
DNA relaxation mediated by Ustilago maydis type I topoisomerase; modulation by chromatin associated proteins.. 1173. 1993
23Na-NMR study of ion transport across vesicle membranes facilitated by phenylalanine analogs of gramicidin.. 1146. 1993
Monoclonal antibody AG-1 initiates platelet activation by a pathway dependent on glycoprotein IIb-IIIa and extracellular calcium.. 1137. 1992
Hypoxia increases stimulus-induced PAF production and release from human umbilical vein endothelial cells.. 1128. 1992
Plasma lipid transport in the preruminant calf, Bos spp: primary structure of bovine apolipoprotein A-I.. 1123. 1992
Measurement of bioreduction rates of cells with distinct responses to ionizing radiation and cisplatin.. 1093. 1991
Regulation of the phosphoinositide cycle by Na+/H+ exchange and intracellular pH in human platelets.. 1084. 1991
Tumor necrosis factor-alpha stimulates phosphatidylinositol breakdown by phospholipase C to coordinately increase the levels of diacylglycerol, free arachidonic acid and prostaglandins in an osteoblast (MC3T3-E1) cell line.. 1091. 1991
Identification of a detergent-solubilized plasma membrane protein from rat liver recognizing apolipoprotein A-IV.. 1044. 1990
Determination of cysteine on low-density lipoproteins using the fluorescent probe, 5-iodoacetamidofluoresceine.. 1037. 1990
Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway.. 987. 1989
Platelet-activating factor is a general membrane perturbant.. 987. 1989
Kinetics of tryptic hydrolysis as a probe of the structure of human plasma apolipoprotein A-II.. 999. 1989
Spectroscopic studies of the tyrosine residues of human plasma apolipoprotein A-II.. 999. 1989
Metabolism of apolipoprotein A-IV in rat.. 1006. 1989
Rapid modulation of rat adipocyte lipoprotein lipase: effect of calcium, A23187 ionophore, and thrombin.. 1003. 1989
The primary structure of human apolipoprotein A-IV.. 1002. 1989
Control of platelet protein kinase C activation by cyclic AMP.. 970. 1988
A sensitive enzyme-linked immunosorbence assay for the c-fos and v-fos oncoproteins.. 965. 1988
Transbilayer diffusion of phospholipids: dependence on headgroup structure and acyl chain length.. 938. 1988
Preferential incorporation of eicosanoid precursor fatty acids into human umbilical vein endothelial cell phospholipids.. 922. 1987
Human articular chondrocytes acquire 1,25-(OH)2 vitamin D-3 receptors in culture.. 931. 1987
Effect of dimethyl sulfoxide on transformed rat Schwann cells.. 923. 1987
Characterization of prostaglandin endoperoxide synthase from a human cell line.. 877. 1986
A pH titration study on the ionic bridging within lipopolysaccharide aggregates.. 821. 1985
Spontaneous and plasma factor-mediated transfer of pyrenyl cerebrosides between model and native lipoproteins.. 837. 1985
Reversible folding reactions of human apolipoprotein A-I: pressure and guanidinium chloride effects.. 836. 1985
Changes in the chondroitin sulfate-rich region of articular cartilage proteoglycans in experimental osteoarthritis.. 840. 1985
Fluorescence assay of the specificity of human plasma and bovine liver phospholipid transfer proteins.. 835. 1985
Isolation and specificity of rat lecithin: cholesterol acyltransferase: comparison with the human enzyme using reassembled high-density lipoproteins containing ether analogs of phosphatidylcholine.. 833. 1985
Metabolism of normal and modified low-density lipoproteins by macrophage cell lines of murine and human origin.. 833. 1985
Structural and functional analysis of spectrin from neonatal erythrocytes.. 827. 1985
The overshoot phenomenon in cotransport.. 776. 1984
Measurement and prediction of the rates of spontaneous transfer of phospholipids between plasma lipoproteins.. 794. 1984
Thermodynamics of lipid-protein association. Enthalphy of association of apolipoprotein A-II with dimyristoylphosphatidylcholine-cholesterol mixtures.. 794. 1984
Properties of a purified nuclear topoisomerase from L1210 cells.. 741. 1983
Immunochemical analysis of Micrococcus lysodeikticus (luteus) F1-ATPase and its subunits.. 724. 1983
The properties of membranes formed from cyclopentanoid analogues of phosphatidylcholine.. 731. 1983
Action of lecithin:cholesterol acyltransferase on model lipoproteins. Preparation and characterization of model nascent high density lipoprotein.. 713. 1982
Cyclic AMP-binding proteins in human blood platelets detected by photoaffinity labelling.. 719. 1982
Platelet lipoxygenase-dependent oxygen burst. Evidence for differential activation of lipoxygenase in intact and disrupted human platelets.. 712. 1982
Kinetics of spontaneous and plasma-stimulated sphingomyelin transfer.. 712. 1982
Inhibitors of membrane depolarization regulate acetylcholine receptor synthesis by a calcium-dependent, cyclic nucleotide-independent mechanism.. 720. 1982
Effect of saturated and unsaturated fat diets on molecular species of phosphatidylcholine and sphingomyelin of human plasma lipoproteins.. 666. 1981
Stimulation and suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase in normal human fibroblasts by high density lipoprotein subclasses.. 619. 1980
Abnormal effects of hypertriacylglycerolemic very low-density lipoproteins on 3-hydroxy-3-methylglutaryl-CoA reductase activity and viability of cultured bovine aortic endothelial cells.. 618. 1980
The phospholipid-binding and immunochemical properties of amidinated, guanidinated and acetylated apolipoprotein A-II.. 617. 1980
Studies on histamine H2 receptors coupled to cardiac adenylate cyclase. Effects of guanylnucleotides and structural requirements for agonist activity.. 587. 1979
Characterization of low density lipoprotein-like particle in the human aorta from grossly normal and atherosclerotic regions.. 573. 1979
Very low density and low density lipoprotein subfractions in type III and type IV hyperlipoproteinemia. Chemical and physical properties.. 572. 1979
Synthesis of actin by cultured guinea pig megakaryocytes. Complex formation with fibrin.. 543. 1978
The in vitro interaction of human apolipoprotein A-I and high density lipoproteins.. 489. 1977
Thermodynamics of lipid protein associations. Thermodynamics of helix formation in the association of high density apolipoprotein A-I (apoA-I) to dimyristoyl phosphatidylcholine.. 488. 1977
Protein sequencing by computer graphics.. 491. 1977
Isolation and characterization of the surface membranes of fast and slow mammalian skeletal muscle.. 466. 1977
Interaction of apoliprotein C-III with phosphatidylcholine vesicles. Dependence of aproprotein-phospholipid complex formation on vesicle structure.. 486. 1976
Interaction of human plasma apolipoproteins and phospholipids. Semi-quantitative studies using polyacrylamide gel electrophoresis.. 398. 1975
Inhibition of delta-aminolevulinate synthetase induction by alpha-amanitin in avian liver cell cultures.. 361. 1974
Localization of low-density lipoproteins in atherosclerotic lesions from human normolipemics employing a purified fluorescent-labeled antibody.. 351. 1974
Effect of the composition of the inner bathing solution on transport properties of the frog skin.. 311. 1973
Interaction of phosphatidylcholine and apolipoprotein-alanine: electron microscopic studies.. 296. 1973
A study of the cystine-containing apolipoprotein of human plasma high density lipoproteins: characterization of cyanogen bromide and tryptic fragments.. 285. 1972
Circular dichroic studies of human plasma retinol-binding protein and prealbumin.. 271. 1972
Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. I. Arrest of collagen accumulation in growing chick embryos.. 236. 1971
Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. II. Morphological and physical properties of collagen containing the analogue.. 236. 1971
A comparison of inhibition of steady state, new transport, and exchange fluxes of amino acids in brain slices.. 203. 1970
Thallium-induced dephosphorylation of a phosphorylated intermediate of the (sodium plus thallium-activated) ATPase.. 178. 1969
Partial delipidation of human serum beta-lipoprotein by sodium decyl sulfate.. 176. 1969
Thallium activation of K+-activated phosphatases from beef brain.. 173. 1969
Carbon tetrachloride-induced loss of microsomal messenger-ribonucleic acid activity.. 145. 1967
The metabolism of purine compounds in Ehrlich ascites tumor cells: evidence for a salvage pathway of inosine metabolism.. 138. 1967
NUCLEOSIDE METABOLISM IN EHRLICH ASCITES TUMOR CELLS: PHOSPHOROLYSIS OF PURINE NUCLEOSIDES.. 80. 1964
Crystalline tartronic semialdehyde reductase from Pseudomonas ovalis Chester.. 48. 1961
The cellular lipid landscape.. 1861. 2016
The role of soluble adenylyl cyclase in health and disease.. 1842. 2014
Superman's eyes.. 1724. 2005
Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer. 2016
NAD(+) metabolism: Bioenergetics, signaling and manipulation for therapy. 2016
Lipid topogenesis--35years on. 2016
Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death. 2016
Ischemic A/D transition of mitochondrial complex I and its role in ROS generation. 2016
Adipocyte-derived factors in age-related dementia and their contribution to vascular and Alzheimer pathology. 2015
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment. 2015
Established breast cancer risk factors and risk of intrinsic tumor subtypes. 2015
Functional mechanisms of neurotransmitter transporters regulated by lipid-protein interactions of their terminal loops. 2015
Control of protein function by prolyl isomerization. 2014
Investigation of cAMP microdomains as a path to novel cancer diagnostics. 2014
Role of soluble adenylyl cyclase in mitochondria. 2014
Characterisation of the active/de-active transition of mitochondrial complex I. 2014
Function of site-2 proteases in bacteria and bacterial pathogens. 2013
A molecular rheostat at the interface of cancer and diabetes. 2013
The fat side of prostate cancer. 2013
Histone exchange and histone modifications during transcription and aging. 2013
New pieces of a puzzle: the current biological picture of MPN. 2012
The in vivo role of nuclear receptor corepressors in thyroid hormone action. 2012
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers. 2011
Folding and misfolding of alpha-synuclein on membranes. 2011
Structural correlates of selectivity and inactivation in potassium channels. 2011
The correlation between multidomain enzymes and multiple activation mechanisms--the case of phospholipase Cβ and its membrane interactions. 2011
Emerging roles for retinoids in regeneration and differentiation in normal and disease states. 2011
Hiding in plain sight: uncovering a new function of vitamin A in redox signaling. 2011
Autosomal dominant polycystic kidney disease: genetics, mutations and microRNAs. 2011
CLC channels and transporters: proteins with borderline personalities. 2010
Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. 2009
Impaired mitochondrial trafficking in Huntington's disease. 2009
Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression. 2009
Intracellular sterol dynamics. 2009
Anti- and pro-tumor functions of autophagy. 2009
Targeting post-mitochondrial effectors of apoptosis for neuroprotection. 2008
Structure and function of phosphatidylcholine transfer protein (PC-TP)/StarD2. 2007
Pharmacogenomics of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. 2006
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction. 2005
Protein sorting in the Golgi complex: shifting paradigms. 2005
Watching the components of photosynthetic bacterial membranes and their in situ organisation by atomic force microscopy. 2005
Involvement of neutral endopeptidase in neoplastic progression. 2004
Lipid and cholesterol trafficking in NPC. 2004
Bioenergetics of mitochondrial diseases associated with mtDNA mutations. 2004
Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility. 2002
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors. 2002
The annexinopathies: a new category of diseases. 2000
Mitochondrial bioenergetics in aging. 2000
Clinical resistance to topoisomerase-targeted drugs. 1998
COPI in ER/Golgi and intra-Golgi transport: do yeast COPI mutants point the way? 1998
Signal transduction by wild-type and leukemogenic Abl proteins. 1997
Lipid-protein interactions in the plasma lipoproteins. 1977

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