Proceedings of the National Academy of Sciences of the United States of America
Journal
Overview
publication venue for
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A T-cell receptor associated with naturally occurring human tumor immunity.
2007
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Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.
2000
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Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma.
1999
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The molecular defect of ferrochelatase in a patient with erythropoietic protoporphyria.
1992
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Detection of antibody to autologous human leukemia cells by immune adherence assays.
1977
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Rationale for combined use of fetal liver and thymus for immunological reconstitution in patients with variants of severe combined immunodeficiency.
1977
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Forces and energetics of the canonical tetrameric cation channel gating..
120.
2023
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Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity..
120.
2023
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Multiple models for outbreak decision support in the face of uncertainty..
120.
2023
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The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching..
120.
2023
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Molecular profiling of the stroke-induced alterations in the cerebral microvasculature reveals promising therapeutic candidates..
120.
2023
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A mutagenesis study of autoantigen optimization for potential T1D vaccine design..
120.
2023
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Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells..
120.
2023
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Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity..
120.
2023
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Early microbial exposure shapes adult immunity by altering CD8+ T cell development..
119.
2022
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Oligodendrocyte precursor cells ingest axons in the mouse neocortex..
119.
2022
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Protective down-regulated states in the human brain: A possible lesson from COVID-19..
119.
2022
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Activity in a prefrontal-periaqueductal gray circuit overcomes behavioral and endocrine features of the passive coping stress response..
119.
2022
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Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responses..
119.
2022
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Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins..
119.
2022
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Real-time imaging of Arc/Arg3.1 transcription ex vivo reveals input-specific immediate early gene dynamics..
119.
2022
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Structural mechanism for bidirectional actin cross-linking by T-plastin..
119.
2022
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Small molecule photocatalysis enables drug target identification via energy transfer..
119.
2022
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The circadian clock mediates daily bursts of cell differentiation by periodically restricting cell-differentiation commitment..
119.
2022
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Radius measurement via super-resolution microscopy enables the development of a variable radii proximity labeling platform..
119.
2022
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Molecular determinants of pH sensing in the proton-activated chloride channel..
119.
2022
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Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs..
119.
2022
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Experimental evidence of physician social preferences..
119.
2022
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Immune checkpoint inhibitors unleash pathogenic immune responses against the microbiota..
119.
2022
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Metabolic and immune-sensitive contacts between lipid droplets and endoplasmic reticulum reconstituted in vitro..
119.
2022
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Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation..
119.
2022
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When the BBB goes MIA..
119.
2022
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A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets..
119.
2022
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Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells' response to Pten deletion..
119.
2022
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Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy..
119.
2022
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Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis..
119.
2022
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BEND3 safeguards pluripotency by repressing differentiation-associated genes..
119.
2022
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Visual pigment-deficient cones survive and mediate visual signaling despite the lack of outer segments..
119.
2022
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Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer..
119.
2022
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Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack..
119.
2022
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Cell-free DNA profiling informs all major complications of hematopoietic cell transplantation..
119.
2022
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Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells..
119.
2022
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Heterologous vaccination interventions to reduce pandemic morbidity and mortality: Modeling the US winter 2020 COVID-19 wave..
119.
2022
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Systems biology analysis of human genomes points to key pathways conferring spina bifida risk..
118.
2021
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Fragility indices for only sufficiently likely modifications..
118.
2021
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Linking function to global and local dynamics in an elevator-type transporter..
118.
2021
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Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization..
118.
2021
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Altered synaptic connectivity and brain function in mice lacking microglial adapter protein Iba1..
118.
2021
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Mechanisms underlying drug-mediated regulation of membrane protein function..
118.
2021
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Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on superenhancers..
118.
2021
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NMDA receptor-BK channel coupling regulates synaptic plasticity in the barrel cortex..
118.
2021
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Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1..
118.
2021
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Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity..
118.
2021
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UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth..
118.
2021
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Characterization of a new SARS-CoV-2 variant that emerged in Brazil..
118.
2021
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Imaging the construction of capillary networks in the neonatal mouse brain..
118.
2021
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Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma..
118.
2021
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Integrative analysis reveals unique structural and functional features of the Smc5/6 complex..
118.
2021
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Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin..
118.
2021
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A unique C2 domain at the C terminus of Munc13 promotes synaptic vesicle priming..
118.
2021
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Dual-process brain mitochondria isolation preserves function and clarifies protein composition..
118.
2021
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mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy..
118.
2021
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Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation..
118.
2021
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Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes..
118.
2021
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Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate..
118.
2021
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Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission..
118.
2021
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A rate threshold mechanism regulates MAPK stress signaling and survival..
118.
2021
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A thermodynamic atlas of carbon redox chemical space..
117.
2020
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E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes..
118.
2020
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FXR mediates T cell-intrinsic responses to reduced feeding during infection..
117.
2020
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High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging..
117.
2020
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mGreenLantern: a bright monomeric fluorescent protein with rapid expression and cell filling properties for neuronal imaging..
117.
2020
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Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma..
117.
2020
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Selectivity filter ion binding affinity determines inactivation in a potassium channel..
117.
2020
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CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response..
117.
2020
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SurA is a cryptically grooved chaperone that expands unfolded outer membrane proteins..
117.
2020
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Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression..
117.
2020
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The eukaryotic translation initiation factor eIF4E elevates steady-state m7G capping of coding and noncoding transcripts..
117.
2020
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Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores..
117.
2020
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How cholesterol stiffens unsaturated lipid membranes..
117.
2020
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Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine..
117.
2020
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A multilayered repair system protects the mycobacterial chromosome from endogenous and antibiotic-induced oxidative damage..
117.
2020
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Bacterial immunotherapy for cancer induces CD4-dependent tumor-specific immunity through tumor-intrinsic interferon-γ signaling..
117.
2020
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L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins..
117.
2020
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Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development..
117.
2020
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Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy..
117.
2020
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TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis..
117.
2020
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Kinetochore protein Spindly controls microtubule polarity in Drosophila axons..
117.
2020
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A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice..
117.
2020
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Noninvasive hippocampal blood-brain barrier opening in Alzheimer's disease with focused ultrasound..
117.
2020
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Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation..
117.
2020
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Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity..
117.
2020
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Bed nuclei of the stria terminalis modulate memory consolidation via glucocorticoid-dependent and -independent circuits..
117.
2020
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Chromosome-free bacterial cells are safe and programmable platforms for synthetic biology..
117.
2020
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Momentum-resolved superconducting energy gaps of Sr2RuO4 from quasiparticle interference imaging..
117.
2020
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The aging skin microenvironment dictates stem cell behavior..
117.
2020
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Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection..
117.
2020
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Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation..
117.
2020
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High-complexity extracellular barcoding using a viral hemagglutinin..
117.
2020
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Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes..
117.
2020
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HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry..
117.
2019
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Ventral hippocampus interacts with prelimbic cortex during inhibition of threat response via learned safety in both mice and humans..
116.
2019
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PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor..
116.
2019
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Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome..
116.
2019
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Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline..
116.
2019
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Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin..
116.
2019
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A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection..
116.
2019
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Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues..
116.
2019
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Repurposing dasatinib for diffuse large B cell lymphoma..
116.
2019
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The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor..
116.
2019
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YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity..
116.
2019
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Structural basis for adenylation and thioester bond formation in the ubiquitin E1..
116.
2019
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Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology..
116.
2019
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JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors..
116.
2019
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Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins..
116.
2019
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BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection..
116.
2019
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Aneuploidy drives lethal progression in prostate cancer..
116.
2019
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Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis..
116.
2019
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Genomic correlates of clinical outcome in advanced prostate cancer..
116.
2019
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Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila..
116.
2019
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Target identification reveals lanosterol synthase as a vulnerability in glioma..
116.
2019
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Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations..
116.
2019
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Array atomic force microscopy for real-time multiparametric analysis..
116.
2019
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HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2..
116.
2019
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ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation..
116.
2019
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Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer..
116.
2019
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Identifying coupled clusters of allostery participants through chemical shift perturbations..
116.
2019
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Patched1-ArhGAP36-PKA-Inversin axis determines the ciliary translocation of Smoothened for Sonic Hedgehog pathway activation..
116.
2018
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Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer..
116.
2018
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The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool..
115.
2018
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Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruption..
115.
2018
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RNA polymerase II CTD interactome with 3' processing and termination factors in fission yeast and its impact on phosphate homeostasis..
115.
2018
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Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth..
115.
2018
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Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1..
115.
2018
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Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11..
115.
2018
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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1)..
115.
2018
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ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB..
115.
2018
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Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy..
115.
2018
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Structural titration of receptor ion channel GLIC gating by HS-AFM..
115.
2018
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N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle..
115.
2018
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The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites..
115.
2018
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Acetyl-l-carnitine deficiency in patients with major depressive disorder..
115.
2018
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Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance..
115.
2018
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Molecular profiling of reticular gigantocellularis neurons indicates that eNOS modulates environmentally dependent levels of arousal..
115.
2018
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Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance..
115.
2018
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Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases..
115.
2018
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Changes in white matter in mice resulting from low-frequency brain stimulation..
115.
2018
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RalA controls glucose homeostasis by regulating glucose uptake in brown fat..
115.
2018
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YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics..
115.
2018
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Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing..
115.
2018
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Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation..
115.
2018
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HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions..
115.
2018
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Digitizing omics profiles by divergence from a baseline..
115.
2018
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Ridding fMRI data of motion-related influences: Removal of signals with distinct spatial and physical bases in multiecho data..
115.
2018
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Damaging de novo mutations diminish motor skills in children on the autism spectrum..
115.
2018
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16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development..
115.
2018
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Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain..
115.
2018
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Human airway branch variation and chronic obstructive pulmonary disease..
115.
2018
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Fenofibrate prevents skeletal muscle loss in mice with lung cancer..
115.
2018
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Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy..
115.
2018
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Aminoglycoside interactions and impacts on the eukaryotic ribosome..
114.
2017
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Rapid diagnostic testing platform for iron and vitamin A deficiency..
114.
2017
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Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA)..
114.
2017
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Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology..
114.
2017
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DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma..
114.
2017
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Kinesin-dependent mechanism for controlling triglyceride secretion from the liver..
114.
2017
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Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains..
114.
2017
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Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer..
114.
2017
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Miscoding-induced stalling of substrate translocation on the bacterial ribosome..
114.
2017
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Cross-scale effects of neural interactions during human neocortical seizure activity..
114.
2017
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Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen..
114.
2017
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NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor..
114.
2017
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Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models..
114.
2017
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Dorsolateral prefrontal cortex GABA deficit in older adults with sleep-disordered breathing..
114.
2017
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Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma..
114.
2017
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Proteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart..
114.
2017
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Atypical fracture with long-term bisphosphonate therapy is associated with altered cortical composition and reduced fracture resistance..
114.
2017
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Poly(ADP-ribose) polymerase 1 escorts XPC to UV-induced DNA lesions during nucleotide excision repair..
114.
2017
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BRCT-domain protein BRIT1 influences class switch recombination..
114.
2017
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Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing..
114.
2017
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Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations..
114.
2017
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Bidirectional regulation of Aβ levels by Presenilin 1..
114.
2017
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Dynamic remodeling of the dynamin helix during membrane constriction..
114.
2017
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Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma..
114.
2017
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Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults..
114.
2017
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Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload..
114.
2017
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Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia..
114.
2017
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Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development..
114.
2017
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Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors..
114.
2017
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Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis..
114.
2017
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Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1..
114.
2017
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PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation..
114.
2017
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Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring..
114.
2017
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Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties..
114.
2017
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Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis..
114.
2017
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Rhythmic brain stimulation reduces anxiety-related behavior in a mouse model based on meditation training..
114.
2017
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Direct visualization of glutamate transporter elevator mechanism by high-speed AFM..
114.
2017
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Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage..
114.
2017
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Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas..
114.
2017
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Matrix stiffening promotes a tumor vasculature phenotype..
114.
2016
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FGF14 is a regulator of KCNQ2/3 channels..
114.
2016
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Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice..
113.
2016
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Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation..
113.
2016
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A functional role for intrinsic disorder in the tau-tubulin complex..
113.
2016
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Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA..
113.
2016
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Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK..
113.
2016
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Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice..
113.
2016
-
Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain..
113.
2016
-
Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes..
113.
2016
-
Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites..
113.
2016
-
Human amygdala engagement moderated by early life stress exposure is a biobehavioral target for predicting recovery on antidepressants..
113.
2016
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Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma..
113.
2016
-
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination..
113.
2016
-
Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus..
113.
2016
-
Genetic drivers of vulnerability and resistance in relapsed acute lymphoblastic leukemia..
113.
2016
-
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis..
113.
2016
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PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front..
113.
2016
-
Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein..
113.
2016
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Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy..
113.
2016
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N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis..
113.
2016
-
Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation..
113.
2016
-
Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors..
113.
2016
-
Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus..
113.
2016
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Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair..
113.
2016
-
Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome..
113.
2016
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The Pseudomonas aeruginosa efflux pump MexGHI-OpmD transports a natural phenazine that controls gene expression and biofilm development..
113.
2016
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Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species..
113.
2016
-
δ-COP modulates Aβ peptide formation via retrograde trafficking of APP..
113.
2016
-
Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity..
113.
2016
-
Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function..
113.
2016
-
Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels..
113.
2016
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Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species..
113.
2016
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Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas..
113.
2016
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Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration..
113.
2016
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MEKK2 mediates an alternative β-catenin pathway that promotes bone formation..
113.
2016
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Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis..
113.
2016
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Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes..
113.
2016
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Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers..
113.
2016
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Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice..
113.
2016
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p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism..
113.
2016
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Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum..
113.
2016
-
Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1..
112.
2015
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Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer..
112.
2015
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Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass..
112.
2015
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Ion-binding properties of a K+ channel selectivity filter in different conformations..
112.
2015
-
Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration..
112.
2015
-
Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatment..
112.
2015
-
Automatic classification of prostate cancer Gleason scores from multiparametric magnetic resonance images..
112.
2015
-
Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes..
112.
2015
-
Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes..
112.
2015
-
Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission..
112.
2015
-
90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin's lymphoma..
112.
2015
-
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress..
112.
2015
-
STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node..
112.
2015
-
SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia..
112.
2015
-
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens..
112.
2015
-
Fibroblast growth factor 9 is a novel modulator of negative affect..
112.
2015
-
Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling..
112.
2015
-
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM..
112.
2015
-
Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors..
112.
2015
-
Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum..
112.
2015
-
Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination..
112.
2015
-
IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions..
112.
2015
-
Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease..
112.
2015
-
Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial..
112.
2015
-
Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1..
112.
2015
-
Imaging metabolite dynamics in living cells using a Spinach-based riboswitch..
112.
2015
-
CD4 mimetics sensitize HIV-1-infected cells to ADCC..
112.
2015
-
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling..
112.
2015
-
Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response..
112.
2015
-
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography..
112.
2015
-
The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation..
112.
2015
-
Opinion: Addressing systemic problems in the biomedical research enterprise..
112.
2015
-
Metabolic resting-state brain networks in health and disease..
112.
2015
-
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics..
112.
2015
-
Only three driver gene mutations are required for the development of lung and colorectal cancers..
112.
2014
-
Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells..
112.
2014
-
Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels..
111.
2014
-
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms..
111.
2014
-
p53 prevents neurodegeneration by regulating synaptic genes..
111.
2014
-
ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis..
111.
2014
-
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex..
111.
2014
-
Nitric oxide regulates synaptic transmission between spiny projection neurons..
111.
2014
-
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome..
111.
2014
-
Human NLRP3 inflammasome senses multiple types of bacterial RNAs..
111.
2014
-
Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season..
111.
2014
-
MAGI-2 scaffold protein is critical for kidney barrier function..
111.
2014
-
Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states..
111.
2014
-
α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation..
111.
2014
-
Network measures predict neuropsychological outcome after brain injury..
111.
2014
-
Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output..
111.
2014
-
Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid..
111.
2014
-
Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans..
111.
2014
-
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma..
111.
2014
-
Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells..
111.
2014
-
Functional B-1 progenitor cells are present in the hematopoietic stem cell-deficient embryo and depend on Cbfβ for their development..
111.
2014
-
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems..
111.
2014
-
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state..
111.
2014
-
Copy number alteration burden predicts prostate cancer relapse..
111.
2014
-
Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3..
111.
2014
-
Assessment and risk analysis of casing and cement impairment in oil and gas wells in Pennsylvania, 2000-2012..
111.
2014
-
Major mouse placental compartments revealed by diffusion-weighted MRI, contrast-enhanced MRI, and fluorescence imaging..
111.
2014
-
Defining a personal, allele-specific, and single-molecule long-read transcriptome..
111.
2014
-
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin..
111.
2014
-
Recovery of consciousness is mediated by a network of discrete metastable activity states..
111.
2014
-
Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide..
111.
2014
-
NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents..
111.
2014
-
Synaptic function of nicastrin in hippocampal neurons..
111.
2014
-
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling..
111.
2014
-
Fluid shear stress threshold regulates angiogenic sprouting..
111.
2014
-
Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY..
111.
2014
-
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis..
111.
2014
-
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia..
111.
2014
-
Histone variant H3.3 is an essential maternal factor for oocyte reprogramming..
111.
2014
-
Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition..
111.
2014
-
Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer..
111.
2014
-
Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells..
111.
2014
-
GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling..
111.
2014
-
An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity..
111.
2014
-
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences..
111.
2014
-
Regional cerebral metabolic patterns demonstrate the role of anterior forebrain mesocircuit dysfunction in the severely injured brain..
111.
2014
-
Rescuing US biomedical research from its systemic flaws..
111.
2014
-
Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium..
111.
2014
-
Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids..
111.
2014
-
Molecular dissection of the evolution of carbapenem-resistant multilocus sequence type 258 Klebsiella pneumoniae..
111.
2014
-
Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation..
111.
2014
-
Four-dimensional live imaging of apical biosynthetic trafficking reveals a post-Golgi sorting role of apical endosomal intermediates..
111.
2014
-
Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast..
111.
2014
-
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate..
111.
2014
-
Circulating giant macrophages as a potential biomarker of solid tumors..
111.
2014
-
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology..
111.
2014
-
Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8..
111.
2014
-
Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer..
111.
2014
-
PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair..
111.
2014
-
Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression..
111.
2014
-
TRAIL-coated leukocytes that kill cancer cells in the circulation..
111.
2014
-
Structure of a eukaryotic thiaminase I..
111.
2013
-
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer..
110.
2013
-
Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis..
110.
2013
-
NFATc1 and NFATc2 repress spontaneous osteoarthritis..
110.
2013
-
Site-2 protease substrate specificity and coupling in trans by a PDZ-substrate adapter protein..
110.
2013
-
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence..
110.
2013
-
Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels..
110.
2013
-
Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation..
110.
2013
-
Early-life stress has persistent effects on amygdala function and development in mice and humans..
110.
2013
-
Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression..
110.
2013
-
Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma..
110.
2013
-
Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk..
110.
2013
-
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT..
110.
2013
-
Prototype of an intertwined secondary-metabolite supercluster..
110.
2013
-
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice..
110.
2013
-
Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation..
110.
2013
-
Self-assembly and sorting of acentrosomal microtubules by TACC3 facilitate kinetochore capture during the mitotic spindle assembly..
110.
2013
-
Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis..
110.
2013
-
Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro..
110.
2013
-
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)..
110.
2013
-
Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle..
110.
2013
-
Tuning a riboswitch response through structural extension of a pseudoknot..
110.
2013
-
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling..
110.
2013
-
Brief meditation training induces smoking reduction..
110.
2013
-
ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer..
110.
2013
-
From the Cover: Neutralization of terminal differentiation in gliomagenesis..
110.
2013
-
Polo kinase Cdc5 is a central regulator of meiosis I..
110.
2013
-
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins..
110.
2013
-
Structure and function of CarD, an essential mycobacterial transcription factor..
110.
2013
-
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ..
110.
2013
-
Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells..
110.
2013
-
EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype..
110.
2013
-
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding..
110.
2013
-
Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK..
110.
2013
-
Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site..
110.
2013
-
Acoustic echoes reveal room shape..
110.
2013
-
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss..
110.
2013
-
Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis..
110.
2013
-
Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis..
110.
2013
-
Structural insights into the N-terminal GIY-YIG endonuclease activity of Arabidopsis glutaredoxin AtGRXS16 in chloroplasts..
110.
2013
-
Ultrastructural analysis of hepatitis C virus particles..
110.
2013
-
Tissue plasminogen activator regulates Purkinje neuron development and survival..
110.
2013
-
Circadian patterns of gene expression in the human brain and disruption in major depressive disorder..
110.
2013
-
Chloride binding site of neurotransmitter sodium symporters..
110.
2013
-
Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α..
110.
2013
-
Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155..
110.
2013
-
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro..
110.
2013
-
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover..
110.
2013
-
c-Myc phosphorylation by PKCζ represses prostate tumorigenesis..
110.
2013
-
Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis..
110.
2013
-
Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH..
110.
2013
-
Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations..
110.
2013
-
Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution..
110.
2013
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9..
110.
2013
-
Remyelination reporter reveals prolonged refinement of spontaneously regenerated myelin..
110.
2013
-
Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis..
110.
2013
-
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy..
110.
2013
-
Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development..
110.
2013
-
Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR..
110.
2013
-
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1..
110.
2013
-
Genetic heterogeneity of diffuse large B-cell lymphoma..
110.
2013
-
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications..
110.
2012
-
Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal-fetal interface..
110.
2012
-
Two methods for full-length RNA sequencing for low quantities of cells and single cells..
110.
2012
-
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells..
109.
2012
-
Chemogenomic approach identified yeast YLR143W as diphthamide synthetase..
109.
2012
-
Long-term influence of normal variation in neonatal characteristics on human brain development..
109.
2012
-
Multimodal imaging of the self-regulating developing brain..
109.
2012
-
Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins..
109.
2012
-
Microfluidics separation reveals the stem-cell-like deformability of tumor-initiating cells..
109.
2012
-
Punctuation and syntax of the RNA polymerase II CTD code in fission yeast..
109.
2012
-
Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α-dependent function..
109.
2012
-
Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-κB acetylation and transcription..
109.
2012
-
Altered fear learning across development in both mouse and human..
109.
2012
-
Synthesis of site-specific antibody-drug conjugates using unnatural amino acids..
109.
2012
-
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials..
109.
2012
-
Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses..
109.
2012
-
Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival..
109.
2012
-
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer..
109.
2012
-
Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome..
109.
2012
-
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro..
109.
2012
-
Retinal prosthetic strategy with the capacity to restore normal vision..
109.
2012
-
STAT3 negatively regulates thyroid tumorigenesis..
109.
2012
-
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model..
109.
2012
-
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1..
109.
2012
-
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate..
109.
2012
-
Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids..
109.
2012
-
Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell..
109.
2012
-
Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior..
109.
2012
-
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis..
109.
2012
-
Mechanisms of white matter changes induced by meditation..
109.
2012
-
Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor..
109.
2012
-
In vitro microvessels for the study of angiogenesis and thrombosis..
109.
2012
-
Oncogene-mediated alterations in chromatin conformation..
109.
2012
-
Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells..
109.
2012
-
2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy..
109.
2012
-
Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission..
109.
2012
-
Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor..
109.
2012
-
Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk..
109.
2012
-
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus..
109.
2012
-
Similar temporal and spatial recruitment of native 19S and 20S proteasome subunits to transcriptionally active chromatin..
109.
2012
-
Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory..
109.
2012
-
Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance..
109.
2012
-
Promiscuous binding of extracellular peptides to cell surface class I MHC protein..
109.
2012
-
Polycomb repressive complex 2 is required for MLL-AF9 leukemia..
109.
2012
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing..
109.
2012
-
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans..
109.
2012
-
Basolateral sorting of the coxsackie and adenovirus receptor through interaction of a canonical YXXPhi motif with the clathrin adaptors AP-1A and AP-1B..
109.
2012
-
High-grade serous ovarian cancer arises from fallopian tube in a mouse model..
109.
2012
-
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response..
109.
2012
-
Modeling hepatitis C virus infection using human induced pluripotent stem cells..
109.
2012
-
Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer..
109.
2012
-
Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1..
109.
2012
-
BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus..
109.
2012
-
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways..
108.
2011
-
IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis..
108.
2011
-
The inflammatory cytokine IL-18 induces self-reactive innate antibody responses regulated by natural killer T cells..
108.
2011
-
Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy..
108.
2011
-
Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers..
108.
2011
-
Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation..
108.
2011
-
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer..
108.
2011
-
Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging..
108.
2011
-
A soluble α-synuclein construct forms a dynamic tetramer..
108.
2011
-
Antitumorigenic potential of STAT3 alternative splicing modulation..
108.
2011
-
Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1)..
108.
2011
-
Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF..
108.
2011
-
Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis..
108.
2011
-
Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab..
108.
2011
-
Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines..
108.
2011
-
Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo..
108.
2011
-
Behavioral and neural correlates of delay of gratification 40 years later..
108.
2011
-
Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation..
108.
2011
-
Parallel adaptive feedback enhances reliability of the Ca2+ signaling system..
108.
2011
-
Expansion of a unique CD57⁺NKG2Chi natural killer cell subset during acute human cytomegalovirus infection..
108.
2011
-
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function..
108.
2011
-
Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin..
108.
2011
-
Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine..
108.
2011
-
Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling..
108.
2011
-
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission..
108.
2011
-
Humanized mice with ectopic artificial liver tissues..
108.
2011
-
Oscillatory patterns in temporal lobe reveal context reinstatement during memory search..
108.
2011
-
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures..
108.
2011
-
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody..
108.
2011
-
Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites..
108.
2011
-
Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA..
108.
2011
-
Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation..
108.
2011
-
Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity..
108.
2011
-
Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor..
108.
2011
-
Characterization of a canine homolog of hepatitis C virus..
108.
2011
-
Forces guiding assembly of light-harvesting complex 2 in native membranes..
108.
2011
-
Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen..
108.
2011
-
Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation..
108.
2011
-
Reversible suppression of an essential gene in adult mice using transgenic RNA interference..
108.
2011
-
Cerebellothalamocortical pathway abnormalities in torsinA DYT1 knock-in mice..
108.
2011
-
Solid-phase synthesis and chemical space analysis of a 190-membered alkaloid/terpenoid-like library..
108.
2011
-
Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts..
108.
2011
-
Mechanism for selectivity-inactivation coupling in KcsA potassium channels..
108.
2011
-
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway..
108.
2011
-
Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase..
108.
2011
-
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation..
108.
2011
-
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta..
108.
2011
-
Mean-field modeling of thalamocortical dynamics and a model-driven approach to EEG analysis..
108 Suppl 3.
2011
-
Benzoquinone ansamycin 17AAG binds to mitochondrial voltage-dependent anion channel and inhibits cell invasion..
108.
2011
-
Depletion of antibiotic targets has widely varying effects on growth..
108.
2011
-
Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients..
108.
2011
-
RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma..
108.
2011
-
Selective early-acquired fear memories undergo temporary suppression during adolescence..
108.
2011
-
TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages..
108.
2011
-
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice..
108.
2011
-
Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations..
108.
2010
-
Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells..
107.
2010
-
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis..
107.
2010
-
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands..
107.
2010
-
IFN-γ abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling..
107.
2010
-
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema..
107.
2010
-
Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodes..
107.
2010
-
Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation..
107.
2010
-
Local statistics in natural scenes predict the saliency of synthetic textures..
107.
2010
-
Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms..
107.
2010
-
A mathematical framework to determine the temporal sequence of somatic genetic events in cancer..
107.
2010
-
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway..
107.
2010
-
Polyamine pathway contributes to the pathogenesis of Parkinson disease..
107.
2010
-
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor..
107.
2010
-
Charges in the hydrophobic interior of proteins..
107.
2010
-
Amphiphile regulation of ion channel function by changes in the bilayer spring constant..
107.
2010
-
Short-term meditation induces white matter changes in the anterior cingulate..
107.
2010
-
TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer..
107.
2010
-
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis..
107.
2010
-
Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells..
107.
2010
-
Evidence of intense ongoing endemic transmission of hepatitis C virus in Egypt..
107.
2010
-
Stress coping stimulates hippocampal neurogenesis in adult monkeys..
107.
2010
-
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner..
107.
2010
-
Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model..
107.
2010
-
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis..
107.
2010
-
Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors..
107.
2010
-
Paradoxical glomerular filtration of carbon nanotubes..
107.
2010
-
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells..
107.
2010
-
Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling..
107.
2010
-
Stereoselective transbilayer translocation of mannosyl phosphoryl dolichol by an endoplasmic reticulum flippase..
107.
2010
-
Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2..
107.
2010
-
A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice..
107.
2010
-
Design of an injectable synthetic and biodegradable surgical biomaterial..
107.
2010
-
Strong synaptic transmission impact by copy number variations in schizophrenia..
107.
2010
-
Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction..
107.
2010
-
Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection..
107.
2010
-
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology..
107.
2010
-
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy..
107.
2010
-
Natural immunity to pluripotency antigen OCT4 in humans..
107.
2010
-
Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors..
107.
2010
-
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration..
107.
2010
-
The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety..
107.
2010
-
Mig-6 controls EGFR trafficking and suppresses gliomagenesis..
107.
2010
-
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB..
107.
2010
-
Combinatorial libraries against libraries for selecting neoepitope activation-specific antibodies..
107.
2010
-
The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation..
107.
2010
-
Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's..
107.
2010
-
Antenna mixing in photosynthetic membranes from Phaeospirillum molischianum..
107.
2010
-
Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells..
107.
2010
-
Distal axonopathy with structural persistence in glaucomatous neurodegeneration..
107.
2010
-
Seromic profiling of ovarian and pancreatic cancer..
107.
2010
-
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle..
107.
2010
-
BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function..
107.
2010
-
MYC regulation of a "poor-prognosis" metastatic cancer cell state..
107.
2010
-
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation..
107.
2010
-
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures..
107.
2010
-
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis..
107.
2010
-
Expression of cancer testis antigen CT45 in classical Hodgkin lymphoma and other B-cell lymphomas..
107.
2010
-
Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages..
107.
2010
-
Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes..
107.
2010
-
Decreased necrotizing fasciitis capacity caused by a single nucleotide mutation that alters a multiple gene virulence axis..
107.
2010
-
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism..
107.
2009
-
Model of human low-density lipoprotein and bound receptor based on cryoEM..
107.
2009
-
Spontaneous formation of the unlocked state of the ribosome is a multistep process..
107.
2009
-
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia..
107.
2009
-
Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis..
107.
2009
-
Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma..
106.
2009
-
Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD..
107.
2009
-
Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production..
106.
2009
-
Epimorphic regeneration approach to tissue replacement in adult mammals..
107.
2009
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy..
107.
2009
-
The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle..
106.
2009
-
Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival..
106.
2009
-
Acute in vivo exposure to interferon-gamma enables resident brain dendritic cells to become effective antigen presenting cells..
106.
2009
-
Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini..
106.
2009
-
HDAC6 is a target for protection and regeneration following injury in the nervous system..
106.
2009
-
Transcriptional regulator Id2 controls survival of hepatic NKT cells..
106.
2009
-
Genetic diagnosis by whole exome capture and massively parallel DNA sequencing..
106.
2009
-
PTEN dosage is essential for neurofibroma development and malignant transformation..
106.
2009
-
Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling..
106.
2009
-
Orai1 internalization and STIM1 clustering inhibition modulate SOCE inactivation during meiosis..
106.
2009
-
Cargo sorting into multivesicular bodies in vitro..
106.
2009
-
Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair..
106.
2009
-
A progenitor cell origin of myeloid malignancies..
106.
2009
-
Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress..
106.
2009
-
Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation..
106.
2009
-
Generation of pluripotent stem cells from patients with type 1 diabetes..
106.
2009
-
Prevascularization of cardiac patch on the omentum improves its therapeutic outcome..
106.
2009
-
Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers..
106.
2009
-
Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells..
106.
2009
-
Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics..
106.
2009
-
CT-X antigen expression in human breast cancer..
106.
2009
-
Akt1 is critical for acute inflammation and histamine-mediated vascular leakage..
106.
2009
-
The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies..
106.
2009
-
BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma..
106.
2009
-
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation..
106.
2009
-
Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells..
106.
2009
-
Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene..
106.
2009
-
The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers..
106.
2009
-
Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-kappaB activation and invasive prostate carcinoma..
106.
2009
-
Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans..
106.
2009
-
Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma..
106.
2009
-
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models..
106.
2009
-
Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene..
106.
2009
-
Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling..
106.
2009
-
Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer..
106.
2009
-
p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis..
106.
2009
-
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease..
106.
2009
-
Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation..
106.
2009
-
Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency..
106.
2009
-
Ruling out and ruling in neural codes..
106.
2009
-
MicroRNA expression profiles predictive of human renal allograft status..
106.
2009
-
Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41..
106.
2009
-
Generation of hyperpolarized substrates by secondary labeling with [1,1-13C] acetic anhydride..
106.
2009
-
Postthymic maturation influences the CD8 T cell response to antigen..
106.
2009
-
Instant immunity through chemically programmable vaccination and covalent self-assembly..
106.
2009
-
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway..
106.
2009
-
Control of extracellular cleavage of ProBDNF by high frequency neuronal activity..
106.
2009
-
Loss of PKC lambda/iota impairs Th2 establishment and allergic airway inflammation in vivo..
106.
2009
-
Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus..
106.
2009
-
The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage..
106.
2009
-
Psychosocial stress reversibly disrupts prefrontal processing and attentional control..
106.
2009
-
Retinol saturase promotes adipogenesis and is downregulated in obesity..
106.
2009
-
Specific transbilayer translocation of dolichol-linked oligosaccharides by an endoplasmic reticulum flippase..
106.
2009
-
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN..
106.
2008
-
Genome-wide analysis of cancer/testis gene expression..
105.
2008
-
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit..
105.
2008
-
GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression..
105.
2008
-
Modulation of RNA polymerase II subunit composition by ubiquitylation..
105.
2008
-
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo..
105.
2008
-
Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer..
105.
2008
-
Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene..
105.
2008
-
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS..
105.
2008
-
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation..
105.
2008
-
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice..
105.
2008
-
Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer..
105.
2008
-
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS..
105.
2008
-
New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity..
105.
2008
-
Rifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active center..
105.
2008
-
Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS..
105.
2008
-
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling..
105.
2008
-
Differentiation of regulatory Foxp3+ T cells in the thymic cortex..
105.
2008
-
Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes..
105.
2008
-
Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger..
105.
2008
-
Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249..
105.
2008
-
Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors..
105.
2008
-
Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation..
105.
2008
-
In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate..
105.
2008
-
Acid sphingomyelinase involvement in tumor necrosis factor alpha-regulated vascular and steroid disruption during luteolysis in vivo..
105.
2008
-
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1..
105.
2008
-
Molecular mechanism of pH sensing in KcsA potassium channels..
105.
2008
-
Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control..
105.
2008
-
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras..
105.
2008
-
A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processing..
105.
2008
-
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33..
105.
2008
-
Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain..
105.
2008
-
HLA alleles determine differences in human natural killer cell responsiveness and potency..
105.
2008
-
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine..
105.
2008
-
Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation..
105.
2008
-
Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance..
105.
2008
-
Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming..
105.
2008
-
Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation..
105.
2008
-
Mast cell renin and a local renin-angiotensin system in the airway: role in bronchoconstriction..
105.
2008
-
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein..
105.
2008
-
Key role of tissue plasminogen activator in neurovascular coupling..
105.
2008
-
D-loop formation by Brh2 protein of Ustilago maydis..
105.
2008
-
Evolutionarily conserved gene family important for fat storage..
105.
2007
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib..
104.
2007
-
Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode..
104.
2007
-
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma..
104.
2007
-
ID genes mediate tumor reinitiation during breast cancer lung metastasis..
104.
2007
-
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome..
104.
2007
-
Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease..
104.
2007
-
Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism..
104.
2007
-
Arousal of cerebral cortex electroencephalogram consequent to high-frequency stimulation of ventral medullary reticular formation..
104.
2007
-
Adult spinal cord progenitor cells are repelled by netrin-1 in the embryonic and injured adult spinal cord..
104.
2007
-
Identification of prostate cancer modifier pathways using parental strain expression mapping..
104.
2007
-
Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals..
104.
2007
-
Short-term meditation training improves attention and self-regulation..
104.
2007
-
Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer..
104.
2007
-
The role of fluctuations in tRNA selection by the ribosome..
104.
2007
-
Loss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte..
104.
2007
-
Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts..
104.
2007
-
A unified genetic theory for sporadic and inherited autism..
104.
2007
-
In vivo imaging of T cell delivery to tumors after adoptive transfer therapy..
104.
2007
-
Cellular cofactors affecting hepatitis C virus infection and replication..
104.
2007
-
Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation..
104.
2007
-
Telomerase core components protect Candida telomeres from aberrant overhang accumulation..
104.
2007
-
The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells..
104.
2007
-
Reversine increases the plasticity of lineage-committed mammalian cells..
104.
2007
-
Chromosomal periodicity of evolutionarily conserved gene pairs..
104.
2007
-
Functional MRI of the zebra finch brain during song stimulation suggests a lateralized response topography..
104.
2007
-
Docosahexaenoic acid alters bilayer elastic properties..
104.
2007
-
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion..
104.
2007
-
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies..
104.
2007
-
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing..
104.
2007
-
Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming..
104.
2007
-
IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation..
104.
2007
-
Fetal gene therapy of alpha-thalassemia in a mouse model..
104.
2007
-
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity..
104.
2007
-
Genomic resources for songbird research and their use in characterizing gene expression during brain development..
104.
2007
-
Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology..
104.
2007
-
Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer..
104.
2007
-
Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo..
104.
2007
-
Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation..
104.
2007
-
CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma..
104.
2007
-
Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse..
104.
2007
-
Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas..
104.
2007
-
Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells..
104.
2007
-
DDB1 is essential for genomic stability in developing epidermis..
104.
2007
-
Evidence for a functional RNA element in the hepatitis C virus core gene..
104.
2007
-
Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome..
104.
2007
-
AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells..
104.
2007
-
Epigenetic memory at malaria virulence genes..
104.
2007
-
Penetrating arterioles are a bottleneck in the perfusion of neocortex..
104.
2006
-
Human lupus autoantibodies against NMDA receptors mediate cognitive impairment..
103.
2006
-
Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants..
103.
2006
-
CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation..
103.
2006
-
Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease..
103.
2006
-
Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models..
103.
2006
-
Self-renewal of embryonic stem cells by a small molecule..
103.
2006
-
Cognitive enhancement with central thalamic electrical stimulation..
103.
2006
-
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2..
103.
2006
-
Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2..
103.
2006
-
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis..
103.
2006
-
Mathematical analysis of locomotor behavior by mice in a radial maze..
103.
2006
-
The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKC epsilon inhibition..
103.
2006
-
Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients..
103.
2006
-
Accurately quantifying low-abundant targets amid similar sequences by revealing hidden correlations in oligonucleotide microarray data..
103.
2006
-
Infant brains detect arithmetic errors..
103.
2006
-
Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells..
103.
2006
-
Factors regulating the abundance and localization of synaptobrevin in the plasma membrane..
103.
2006
-
Breaking the one antibody-one target axiom..
103.
2006
-
RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors..
103.
2006
-
Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance..
103.
2006
-
Identifying genes important for spermatogonial stem cell self-renewal and survival..
103.
2006
-
Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor..
103.
2006
-
Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator..
103.
2006
-
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition..
103.
2006
-
Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus..
103.
2006
-
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions..
103.
2006
-
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development..
103.
2006
-
Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity..
103.
2006
-
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse..
103.
2006
-
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells..
103.
2006
-
Transfer characteristics of the hair cell's afferent synapse..
103.
2006
-
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1..
103.
2006
-
Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells..
103.
2006
-
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro..
103.
2006
-
Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor..
103.
2006
-
Gene expression changes associated with progression and response in chronic myeloid leukemia..
103.
2006
-
Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction..
103.
2006
-
Maternal mediation, stress inoculation, and the development of neuroendocrine stress resistance in primates..
103.
2006
-
Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D..
103.
2006
-
SNOSID, a proteomic method for identification of cysteine S-nitrosylation sites in complex protein mixtures..
103.
2006
-
Immunity and behavior: antibodies alter emotion..
103.
2006
-
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)..
102.
2005
-
Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing..
103.
2005
-
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors..
103.
2005
-
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation..
102.
2005
-
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer..
102.
2005
-
Volumetric tomography of fluorescent proteins through small animals in vivo..
102.
2005
-
The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells..
102.
2005
-
Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair..
102.
2005
-
Polyproline II propensities from GGXGG peptides reveal an anticorrelation with beta-sheet scales..
102.
2005
-
Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation..
102.
2005
-
Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia..
102.
2005
-
Orbitofrontal cortex activity related to emotional processing changes across the menstrual cycle..
102.
2005
-
Mimivirus gene promoters exhibit an unprecedented conservation among all eukaryotes..
102.
2005
-
Dynamic transport of SNARE proteins in the Golgi apparatus..
102.
2005
-
Training, maturation, and genetic influences on the development of executive attention..
102.
2005
-
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer..
102.
2005
-
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway..
102.
2005
-
Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis..
102.
2005
-
Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons..
102.
2005
-
Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6..
102.
2005
-
Diagnosing breast cancer by using Raman spectroscopy..
102.
2005
-
Ancestral antibiotic resistance in Mycobacterium tuberculosis..
102.
2005
-
Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis..
102.
2005
-
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide..
102.
2005
-
p63 regulates commitment to the prostate cell lineage..
102.
2005
-
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases..
102.
2005
-
Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo..
102.
2005
-
Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase..
102.
2005
-
Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase..
102.
2005
-
Inhibition of IFN-alpha signaling by a PKC- and protein tyrosine phosphatase SHP-2-dependent pathway..
102.
2005
-
Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes..
102.
2005
-
Hypnotic suggestion reduces conflict in the human brain..
102.
2005
-
Telomerase can act as a template- and RNA-independent terminal transferase..
102.
2005
-
Control of T helper 2 cell function and allergic airway inflammation by PKCzeta..
102.
2005
-
Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis..
102.
2005
-
High-resolution genomic profiles of human lung cancer..
102.
2005
-
Identification of cancer/testis-antigen genes by massively parallel signature sequencing..
102.
2005
-
p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow..
102.
2005
-
BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes..
102.
2005
-
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability..
102.
2005
-
Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking..
102.
2005
-
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor..
102.
2005
-
Accumulation of miR-155 and BIC RNA in human B cell lymphomas..
102.
2005
-
Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock..
102.
2005
-
Cross-regulation of TNF and IFN-alpha in autoimmune diseases..
102.
2005
-
Inferring network mechanisms: the Drosophila melanogaster protein interaction network..
102.
2005
-
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5)..
102.
2005
-
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice..
102.
2005
-
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance..
102.
2005
-
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris..
102.
2005
-
Intercellular transfer of P-glycoprotein mediates acquired multidrug resistance in tumor cells..
102.
2005
-
Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors..
102.
2005
-
S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense..
102.
2004
-
CD98hc (SLC3A2) mediates integrin signaling..
102.
2004
-
Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate..
102.
2004
-
Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap..
101.
2004
-
Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins..
101.
2004
-
In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase..
102.
2004
-
Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1..
101.
2004
-
Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I..
101.
2004
-
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation..
101.
2004
-
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease..
101.
2004
-
Dead cells in melanoma tumors provide abundant antigen for targeted delivery of ionizing radiation by a mAb to melanin..
101.
2004
-
IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation..
101.
2004
-
Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice..
101.
2004
-
Par-1 promotes a hepatic mode of apical protein trafficking in MDCK cells..
101.
2004
-
NF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survival..
101.
2004
-
Mast cells: a unique source of renin..
101.
2004
-
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase..
101.
2004
-
RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract..
101.
2004
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib..
101.
2004
-
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication..
101.
2004
-
Mechanosensory function of microvilli of the kidney proximal tubule..
101.
2004
-
tRNA dynamics on the ribosome during translation..
101.
2004
-
Derivation of midbrain dopamine neurons from human embryonic stem cells..
101.
2004
-
Nuclear cloning of embryonal carcinoma cells..
101.
2004
-
Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms..
101.
2004
-
Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells..
101.
2004
-
Watching the photosynthetic apparatus in native membranes..
101.
2004
-
Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4(+) and CD8(+) T cell responses in humans..
101.
2004
-
Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C..
101.
2004
-
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity..
101.
2004
-
High-resolution characterization of the pancreatic adenocarcinoma genome..
101.
2004
-
Suppression of tumorigenesis by the p53 target PUMA..
101.
2004
-
Activation of NF-kappaB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis..
101.
2004
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization..
101.
2004
-
Molecular diversity of astrocytes with implications for neurological disorders..
101.
2004
-
Plasticity and tuning by visual feedback of the stability of a neural integrator..
101.
2004
-
Plasticity and tuning of the time course of analog persistent firing in a neural integrator..
101.
2004
-
Development of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7..
101.
2004
-
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle..
101.
2004
-
Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway..
101.
2004
-
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes..
101.
2004
-
Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury..
101.
2004
-
The neural F-box protein NFB42 mediates the nuclear export of the herpes simplex virus type 1 replication initiator protein (UL9 protein) after viral infection..
101.
2004
-
Inhibition of neuronal phenotype by PTEN in PC12 cells..
101.
2004
-
Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin..
101.
2004
-
Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab..
101.
2004
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers..
101.
2004
-
Portability and fidelity of RNA-repair systems..
101.
2004
-
Inducible, reversible, and stable RNA interference in mammalian cells..
101.
2004
-
The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: a member of the DJ-1/ThiJ/PfpI superfamily..
101.
2004
-
Energetics of ion conduction through the gramicidin channel..
101.
2003
-
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells..
100.
2003
-
Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon..
100.
2003
-
Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease..
100.
2003
-
Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients..
100.
2003
-
Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor..
100.
2003
-
Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma..
100.
2003
-
Exploring the functional complexity of cellular proteins by protein knockout..
100.
2003
-
Extensive repetitive DNA facilitates prokaryotic genome plasticity..
100.
2003
-
Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit..
100.
2003
-
Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors..
100.
2003
-
Gleevec inhibits beta-amyloid production but not Notch cleavage..
100.
2003
-
Nonhuman primate parthenogenetic stem cells..
100 Suppl 1.
2003
-
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability..
100.
2003
-
The entry of entry inhibitors: a fusion of science and medicine..
100.
2003
-
An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling..
100.
2003
-
A nuclear target for interleukin-1alpha: interaction with the growth suppressor necdin modulates proliferation and collagen expression..
100.
2003
-
The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3..
100.
2003
-
Identification of transcription coactivator OCA-B-dependent genes involved in antigen-dependent B cell differentiation by cDNA array analyses..
100.
2003
-
Use of avian retroviral vectors to introduce transcriptional regulators into mammalian cells for analyses of tumor maintenance..
100.
2003
-
The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease..
100.
2003
-
Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses..
100.
2003
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1..
100.
2003
-
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway..
100.
2003
-
Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model..
100.
2003
-
Decoding neuronal spike trains: how important are correlations?.
100.
2003
-
Mapping the genetic variation of executive attention onto brain activity..
100.
2003
-
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles..
100.
2003
-
Programming peptidomimetic syntheses by translating genetic codes designed de novo..
100.
2003
-
Ever shorter telomere 1 (EST1)-dependent reverse transcription by Candida telomerase in vitro: evidence in support of an activating function..
100.
2003
-
SHED: stem cells from human exfoliated deciduous teeth..
100.
2003
-
Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst..
100.
2003
-
Immunomic analysis of human sarcoma..
100.
2003
-
Nanodissection and high-resolution imaging of the Rhodopseudomonas viridis photosynthetic core complex in native membranes by AFM. Atomic force microscopy..
100.
2003
-
Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly..
100.
2003
-
Pretarget radiotherapy with an anti-CD25 antibody-streptavidin fusion protein was effective in therapy of leukemia/lymphoma xenografts..
100.
2003
-
Distinct gene expression profiles characterize the histopathological stages of disease in Helicobacter-induced mucosa-associated lymphoid tissue lymphoma..
100.
2003
-
Two Hsp70 family members expressed in atherosclerotic lesions..
100.
2003
-
Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis..
100.
2003
-
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs..
100.
2002
-
Chemical complementation: a reaction-independent genetic assay for enzyme catalysis..
99.
2002
-
Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts..
99.
2002
-
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences..
99.
2002
-
Attentional mechanisms of borderline personality disorder..
99.
2002
-
Preferential induction of apoptosis for primary human leukemic stem cells..
99.
2002
-
Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J x CASA/Rk intercross..
99.
2002
-
Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA)..
99.
2002
-
Control of biochemical reactions through supramolecular RING domain self-assembly..
99.
2002
-
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia..
99.
2002
-
Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation..
99.
2002
-
Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation..
99.
2002
-
Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior..
99.
2002
-
The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts..
99.
2002
-
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling..
99.
2002
-
Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling..
99.
2002
-
A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19..
99.
2002
-
The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin..
99.
2002
-
CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients..
99.
2002
-
Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza..
99.
2002
-
Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop..
99.
2002
-
Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics..
99.
2002
-
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression..
99.
2002
-
Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair..
99.
2002
-
Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes..
99.
2002
-
Endosomal localization and function of sorting nexin 1..
99.
2002
-
Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal..
99.
2002
-
Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6..
99.
2002
-
Protein-protein interactions monitored in mammalian cells via complementation of beta -lactamase enzyme fragments..
99.
2002
-
The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium..
99.
2002
-
Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression..
99.
2002
-
Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON..
99.
2002
-
Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA..
99.
2002
-
The murMN operon: a functional link between antibiotic resistance and antibiotic tolerance in Streptococcuspneumoniae..
99.
2002
-
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium..
99.
2002
-
Self-assembly properties of a model RING domain..
99.
2002
-
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use..
99.
2002
-
Decreased intracellular calcium mediates the histamine H3-receptor-induced attenuation of norepinephrine exocytosis from cardiac sympathetic nerve endings..
99.
2001
-
Multiclass cancer diagnosis using tumor gene expression signatures..
98.
2001
-
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses..
98.
2001
-
Cholesterol depletion induces large scale domain segregation in living cell membranes..
98.
2001
-
Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor..
98.
2001
-
Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects..
98.
2001
-
Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice..
98.
2001
-
Visualizing recycling synaptic vesicles in hippocampal neurons by FM 1-43 photoconversion..
98.
2001
-
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo..
98.
2001
-
Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs..
98.
2001
-
TNF-alpha -dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection..
98.
2001
-
The human decatenation checkpoint..
98.
2001
-
Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke..
98.
2001
-
Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression..
98.
2001
-
Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias..
98.
2001
-
Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET)..
98.
2001
-
An acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococci..
98.
2001
-
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice..
98.
2001
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR..
98.
2001
-
Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo..
98.
2001
-
Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates..
98.
2001
-
The evolution of methicillin resistance in Staphylococcus aureus: similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones..
98.
2001
-
Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomycescerevisiae..
98.
2001
-
Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin..
98.
2001
-
Altered myelopoiesis and the development of acute myeloid leukemia in transgenic mice overexpressing cyclin A1..
98.
2001
-
Developmental plasticity of CNS microglia..
98.
2001
-
Nonlinear-dynamical arrhythmia control in humans..
98.
2001
-
Solution structure of the A loop of 23S ribosomal RNA..
98.
2001
-
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial..
98.
2001
-
Activation of Trk neurotrophin receptors in the absence of neurotrophins..
98.
2001
-
Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes..
98.
2001
-
Coupling of histamine H3 receptors to neuronal Na+/H+ exchange: a novel protective mechanism in myocardial ischemia..
98.
2001
-
Role of the F-box protein Skp2 in lymphomagenesis..
98.
2001
-
Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1..
98.
2001
-
Copper-64-diacetyl-bis(N4-methylthiosemicarbazone): An agent for radiotherapy..
98.
2001
-
Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice..
98.
2001
-
Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors..
97.
2000
-
TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation..
97.
2000
-
Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors..
97.
2000
-
Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers..
97.
2000
-
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles..
97.
2000
-
Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma..
97.
2000
-
Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele..
97.
2000
-
Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling..
97.
2000
-
Abeta 1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation..
97.
2000
-
Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids..
97.
2000
-
Dissociation of response conflict, attentional selection, and expectancy with functional magnetic resonance imaging..
97.
2000
-
The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain..
97.
2000
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5..
97.
2000
-
Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction..
97.
2000
-
Glutathione synthesis is essential for mouse development but not for cell growth in culture..
97.
2000
-
c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency..
97.
2000
-
Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention..
97.
2000
-
Inhibition of the expression of penicillin resistance in Streptococcus pneumoniae by inactivation of cell wall muropeptide branching genes..
97.
2000
-
Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses..
97.
2000
-
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2..
97.
2000
-
Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach..
97.
2000
-
Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer..
97.
2000
-
Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: studies in C57BL/6 apolipoprotein E knockout mice..
97.
2000
-
Saturation of, and competition for entry into, the apical secretory pathway..
97.
2000
-
Transforming growth factor-beta 1 hyperexpression in African-American hypertensives: A novel mediator of hypertension and/or target organ damage..
97.
2000
-
A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells..
97.
2000
-
Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: isolation, quantification, and characterization of immune responses by using totally synthetic immobilized tumor antigens..
97.
2000
-
Hox cluster genomics in the horn shark, Heterodontus francisci..
97.
2000
-
The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest..
97.
2000
-
Testosterone reduces neuronal secretion of Alzheimer's beta-amyloid peptides..
97.
2000
-
Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis..
97.
2000
-
Abundant empty class II MHC molecules on the surface of immature dendritic cells..
96.
1999
-
Extracellular antigen processing and presentation by immature dendritic cells..
96.
1999
-
Transcriptional coupling between the divergent promoters of a prototypic LysR-type regulatory system, the ilvYC operon of Escherichia coli..
96.
1999
-
Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells..
96.
1999
-
Productive infection of double-negative T cells with HIV in vivo..
96.
1999
-
Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched..
96.
1999
-
Transition state heterogeneity in GCN4 coiled coil folding studied by using multisite mutations and crosslinking..
96.
1999
-
Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy..
96.
1999
-
Defective CTLA-4 cycling pathway in Chediak-Higashi syndrome: a possible mechanism for deregulation of T lymphocyte activation..
96.
1999
-
Three-dimensional structure of low density lipoproteins by electron cryomicroscopy..
96.
1999
-
Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis..
96.
1999
-
Acute cholesterol depletion inhibits clathrin-coated pit budding..
96.
1999
-
Carbohydrate vaccines in cancer: immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man..
96.
1999
-
Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide..
96.
1999
-
High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytes..
96.
1999
-
Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium..
96.
1999
-
Tamoxifen inhibits acidification in cells independent of the estrogen receptor..
96.
1999
-
Attention and primary visual cortex..
96.
1999
-
Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules..
96.
1999
-
Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs..
96.
1999
-
Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes..
96.
1999
-
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides..
96.
1999
-
Failure of spinal cord oligodendrocyte development in mice lacking neuregulin..
96.
1999
-
Selective induction of apoptosis by the cytotoxic analog AN-207 in cells expressing recombinant receptor for luteinizing hormone-releasing hormone..
96.
1999
-
Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals..
96.
1999
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway..
95.
1998
-
Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees..
95.
1998
-
The antibody catalysis route to the total synthesis of epothilones..
95.
1998
-
Association of CYP3A4 genotype with treatment-related leukemia..
95.
1998
-
Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans..
95.
1998
-
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma..
95.
1998
-
Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-beta1..
95.
1998
-
Identification of the binding site for Gqalpha on its effector Bruton's tyrosine kinase..
95.
1998
-
Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases..
95.
1998
-
Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase..
95.
1998
-
Increased anxiety of mice lacking the serotonin1A receptor..
95.
1998
-
Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia..
95.
1998
-
A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats..
95.
1998
-
Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption..
95.
1998
-
Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides..
95.
1998
-
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction..
95.
1998
-
Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins..
95.
1998
-
Brain mechanisms of quantity are similar in 5-year-old children and adults..
95.
1998
-
Expressed protein ligation: a general method for protein engineering..
95.
1998
-
Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library..
95.
1998
-
Water does not flow across the tight junctions of MDCK cell epithelium..
95.
1998
-
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression..
95.
1998
-
Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase..
95.
1998
-
Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones..
95.
1998
-
Impact of antigenemia on the bioactivity of infused anti-Tac antibody: implications for dose selection in antibody immunotherapies..
95.
1998
-
Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer..
95.
1998
-
Anatomy of word and sentence meaning..
95.
1998
-
Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice..
95.
1998
-
Modulation of cell death by Bcl-XL through caspase interaction..
95.
1998
-
Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates..
95.
1998
-
Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells..
95.
1998
-
Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes..
94.
1997
-
Targeted deletion of all isoforms of the trkC gene suggests the use of alternate receptors by its ligand neurotrophin-3 in neuronal development and implicates trkC in normal cardiogenesis..
94.
1997
-
Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide..
94.
1997
-
Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase..
94.
1997
-
Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a..
94.
1997
-
Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization..
94.
1997
-
Atomic structure of a thermostable subdomain of HIV-1 gp41..
94.
1997
-
Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism..
94.
1997
-
Conditionally replicating mycobacteriophages: a system for transposon delivery to Mycobacterium tuberculosis..
94.
1997
-
Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein..
94.
1997
-
Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase..
94.
1997
-
Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex..
94.
1997
-
Vitamin A in serum is a survival factor for fibroblasts..
94.
1997
-
Phylogeny of mRNA capping enzymes..
94.
1997
-
Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors..
94.
1997
-
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action..
94.
1997
-
Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast..
94.
1997
-
Identification of nitric oxide synthase as a protective locus against tuberculosis..
94.
1997
-
Peptidyl prolyl cis-trans isomerase activity of cyclophilin A in functional homo-oligomeric receptor expression..
94.
1997
-
Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder..
94.
1997
-
A protein factor that inhibits ATP-dependent glutamate and gamma-aminobutyric acid accumulation into synaptic vesicles: purification and initial characterization..
94.
1997
-
A surface on the G protein beta-subunit involved in interactions with adenylyl cyclases..
94.
1997
-
A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening..
94.
1997
-
Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow..
94.
1997
-
GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus..
94.
1997
-
A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak..
94.
1997
-
Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets..
94.
1997
-
Failure to express the P-selectin gene or P-selectin blockade confers early pulmonary protection after lung ischemia or transplantation..
94.
1997
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor..
94.
1997
-
Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90..
93.
1996
-
A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene..
93.
1996
-
The AML1/ETO fusion protein activates transcription of BCL-2..
93.
1996
-
Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase..
93.
1996
-
Estrogen and thyroid hormone interaction on regulation of gene expression..
93.
1996
-
Thyroid hormone and estrogen interact to regulate behavior..
93.
1996
-
Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain..
93.
1996
-
Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1..
93.
1996
-
Severed corticospinal axons recover electrophysiologic control of muscle activity after x-ray therapy in lesioned adult spinal cord..
93.
1996
-
Structural recovery in lesioned adult mammalian spinal cord by x-irradiation of the lesion site..
93.
1996
-
Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia..
93.
1996
-
Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity..
93.
1996
-
Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways..
93.
1996
-
Mammalian Sug1 and c-Fos in the nuclear 26S proteasome..
93.
1996
-
Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice..
93.
1996
-
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma..
93.
1996
-
Expression of calbindin-D28K in motoneuron hybrid cells after retroviral infection with calbindin-D28K cDNA prevents amyotrophic lateral sclerosis IgG-mediated cytotoxicity..
93.
1996
-
Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi-automated fluorescence-based detection: subregional mapping of chromosome 4 in cervical carcinoma..
93.
1996
-
Serological analysis of Melan-A(MART-1), a melanocyte-specific protein homogeneously expressed in human melanomas..
93.
1996
-
Recombinational repair of gaps in DNA is asymmetric in Ustilago maydis and can be explained by a migrating D-loop model..
93.
1996
-
The timing of synaptic vesicle endocytosis..
93.
1996
-
4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors..
93.
1996
-
Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes..
93.
1996
-
Novel retinoic acid receptor ligands in Xenopus embryos..
93.
1996
-
Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine..
93.
1996
-
Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine..
93.
1996
-
Uptake of fluorescent dyes associated with the functional expression of the cystic fibrosis transmembrane conductance regulator in epithelial cells..
93.
1996
-
Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6..
93.
1996
-
Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes..
93.
1996
-
Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma..
92.
1995
-
Truncated WT1 mutants alter the subnuclear localization of the wild-type protein..
92.
1995
-
Inducible nitric oxide synthase: identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin..
92.
1995
-
Structural and functional analysis of pp70S6k..
92.
1995
-
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation..
92.
1995
-
An astrocytic binding site for neuronal Thy-1 and its effect on neurite outgrowth..
92.
1995
-
Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway..
92.
1995
-
Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae..
92.
1995
-
Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development..
92.
1995
-
Telomerase activity in normal and malignant hematopoietic cells..
92.
1995
-
Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits..
92.
1995
-
Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus..
92.
1995
-
The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei..
92.
1995
-
High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli..
92.
1995
-
Immunophenotyping of melanomas for tyrosinase: implications for vaccine development..
92.
1995
-
Specific induction of cAMP in Langerhans cells by calcitonin gene-related peptide: relevance to functional effects..
92.
1995
-
Interleukin 4 signals through two related pathways..
92.
1995
-
Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types..
92.
1995
-
Transforming growth factor beta mediates the progesterone suppression of an epithelial metalloproteinase by adjacent stroma in the human endometrium..
92.
1995
-
Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene..
92.
1995
-
Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity..
92.
1995
-
A genetic screen identifies cellular factors involved in retroviral -1 frameshifting..
92.
1995
-
Illusory contours activate specific regions in human visual cortex: evidence from functional magnetic resonance imaging..
92.
1995
-
Genetic engineering of vein grafts resistant to atherosclerosis..
92.
1995
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors..
92.
1995
-
Regulation of CD45 engagement by the B-cell receptor CD22..
92.
1995
-
The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice..
92.
1995
-
Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms..
92.
1995
-
Serological response patterns of melanoma patients immunized with a GM2 ganglioside conjugate vaccine..
92.
1995
-
Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma..
92.
1995
-
Voltage-dependent gating of an asymmetric gramicidin channel..
92.
1995
-
Scalp electrical potentials reflect regional cerebral blood flow responses during processing of written words..
92.
1995
-
Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene..
92.
1995
-
Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development..
92.
1995
-
A Staphylococcus aureus autolysin that has an N-acetylmuramoyl-L-alanine amidase domain and an endo-beta-N-acetylglucosaminidase domain: cloning, sequence analysis, and characterization..
92.
1995
-
Comparative genomic analysis of tumors: detection of DNA losses and amplification..
92.
1995
-
Source of nuclear calcium signals..
91.
1994
-
The iron-responsive element binding protein: a target for synaptic actions of nitric oxide..
91.
1994
-
Bone marrow declines as a site of B-cell precursor differentiation with age: relationship to thymus involution..
91.
1994
-
Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases..
91.
1994
-
Isolation of unknown genes from human bone marrow by differential screening and single-pass cDNA sequence determination..
91.
1994
-
The nitric oxide/cyclic GMP pathway in organ transplantation: critical role in successful lung preservation..
91.
1994
-
A role for the acetylcholine receptor-inducing protein ARIA in oligodendrocyte development..
91.
1994
-
AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana, is an essential protein with homology to a calcium-dependent lipid binding domain..
91.
1994
-
A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors..
91.
1994
-
Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney..
91.
1994
-
In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene..
91.
1994
-
Stromal-epithelial interaction mediates steroidal regulation of metalloproteinase expression in human endometrium..
91.
1994
-
The Reed-Sternberg cells of Hodgkin disease are clonal..
91.
1994
-
Preproenkephalin promoter yields region-specific and long-term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector..
91.
1994
-
Striate cortex extracts higher-order spatial correlations from visual textures..
91.
1994
-
Immunotherapy with anti-CD3 monoclonal antibodies and recombinant interleukin 2: stimulation of molecular programs of cytotoxic killer cells and induction of tumor regression..
91.
1994
-
Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24..
91.
1994
-
Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene..
91.
1994
-
Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers..
91.
1994
-
Specificity of protein kinase inhibitor peptides and induction of long-term potentiation..
91.
1994
-
Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors..
91.
1994
-
E-cadherin distribution in interleukin 6-induced cell-cell separation of ductal breast carcinoma cells..
91.
1994
-
Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion..
91.
1994
-
Mutational analysis of yeast mRNA capping enzyme..
91.
1994
-
Na(+)-I- symport activity is present in membrane vesicles from thyrotropin-deprived non-I(-)-transporting cultured thyroid cells..
91.
1994
-
A mouse mutant p53 product recognized by CD4+ and CD8+ T cells..
91.
1994
-
Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells..
91.
1994
-
Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line..
91.
1994
-
A family of cellular proteins related to snake venom disintegrins..
91.
1994
-
Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa..
91.
1994
-
Identification of the MAGE-1 gene product by monoclonal and polyclonal antibodies..
91.
1994
-
Molecular basis of cardiac potassium channel stimulation by protein kinase A..
91.
1994
-
Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway..
91.
1994
-
Age-dependent appearance of non-major histocompatibility complex-restricted helper T cells..
90.
1993
-
Antibody-catalyzed reversal of chemoselectivity..
90.
1993
-
IgG from amyotrophic lateral sclerosis patients increases current through P-type calcium channels in mammalian cerebellar Purkinje cells and in isolated channel protein in lipid bilayer..
90.
1993
-
In vivo protection against endotoxin by plasma high density lipoprotein..
90.
1993
-
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo..
90.
1993
-
Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants..
90.
1993
-
Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase..
90.
1993
-
Sperm 1: a POU-domain gene transiently expressed immediately before meiosis I in the male germ cell..
90.
1993
-
Evidence for linkage of the apolipoprotein A-II locus to plasma apolipoprotein A-II and free fatty acid levels in mice and humans..
90.
1993
-
The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications..
90.
1993
-
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity..
90.
1993
-
Loss of retinoic acid receptor gamma function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment..
90.
1993
-
A possible role for the yeast TATA-element-binding protein in DNA replication..
90.
1993
-
Response variability in retinal ganglion cells of primates..
90.
1993
-
Ultrastructural localization of a neutral and basic amino acid transporter in rat kidney and intestine..
90.
1993
-
Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A..
90.
1993
-
NF-IL6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1..
90.
1993
-
A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations..
90.
1993
-
von Willebrand factor mediates platelet adhesion to virally infected endothelial cells..
90.
1993
-
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3..
90.
1993
-
A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase gene expression..
90.
1993
-
Dystrophin protects the sarcolemma from stresses developed during muscle contraction..
90.
1993
-
Isolation of interleukin 2-induced immediate-early genes..
90.
1993
-
A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex..
90.
1993
-
GD2 ganglioside on human T-lymphotropic virus type I-infected T cells: possible activation of beta-1,4-N-acetylgalactosaminyltransferase gene by p40tax..
90.
1993
-
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex..
90.
1993
-
Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4..
90.
1993
-
Nitric oxide synthase in macula densa regulates glomerular capillary pressure..
89.
1992
-
Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors..
89.
1992
-
Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer..
89.
1992
-
Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels..
89.
1992
-
Simian virus 40 minichromosomes as targets for retroviral integration in vivo..
89.
1992
-
Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation..
89.
1992
-
Mouse macrophage receptor for acetylated low density lipoprotein: demonstration of a fully functional subunit in the membrane and with purified receptor..
89.
1992
-
Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells..
89.
1992
-
Changes in intracellular calcium during the development of epithelial polarity and junctions..
89.
1992
-
Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun..
89.
1992
-
Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine..
89.
1992
-
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells..
89.
1992
-
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo..
89.
1992
-
Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine..
89.
1992
-
Does nitric oxide mediate the increases in cerebral blood flow elicited by hypercapnia?.
89.
1992
-
On the use of the transmembrane domain of bacteriorhodopsin as a template for modeling the three-dimensional structure of guanine nucleotide-binding regulatory protein-coupled receptors..
89.
1992
-
Photoaffinity labeling of avermectin binding sites from Caenorhabditis elegans and Drosophila melanogaster..
89.
1992
-
Thrombomodulin gene regulation by cAMP and retinoic acid in F9 embryonal carcinoma cells..
89.
1992
-
A negative retinoic acid response element in the rat oxytocin promoter restricts transcriptional stimulation by heterologous transactivation domains..
89.
1992
-
An RNA pseudoknot and an optimal heptameric shift site are required for highly efficient ribosomal frameshifting on a retroviral messenger RNA..
89.
1992
-
Yeast casein kinase I homologues: an essential gene pair..
89.
1992
-
Characterization of the promoter of the human gene encoding the high-affinity IgG receptor: transcriptional induction by gamma-interferon is mediated through common DNA response elements..
88.
1991
-
Infrared spectroscopy of exfoliated human cervical cells: evidence of extensive structural changes during carcinogenesis..
88.
1991
-
An extraovarian protein accumulated in mosquito oocytes is a carboxypeptidase activated in embryos..
88.
1991
-
Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha..
88.
1991
-
Heterotropic interactions in aspartate transcarbamoylase: turning allosteric ATP activation into inhibition as a consequence of a single tyrosine to phenylalanine mutation..
88.
1991
-
Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa..
88.
1991
-
Human immunodeficiency virus induction of malignant transformation in human B lymphocytes..
88.
1991
-
Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein..
88.
1991
-
Identification of a monocyte receptor on herpesvirus-infected endothelial cells..
88.
1991
-
The low-affinity p75 nerve growth factor (NGF) receptor mediates NGF-induced tyrosine phosphorylation..
88.
1991
-
Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ..
88.
1991
-
Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis..
88.
1991
-
Interleukin 6 enhances a cellular activity that functionally substitutes for E1A protein in transactivation..
88.
1991
-
Rhodopsin mutations in autosomal dominant retinitis pigmentosa..
88.
1991
-
Isolation of a metal-activated transcription factor gene from Candida glabrata by complementation in Saccharomyces cerevisiae..
88.
1991
-
Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1..
88.
1991
-
Observation of the light-triggered binding of pyrone to chymotrypsin by Laue x-ray crystallography..
88.
1991
-
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia..
88.
1991
-
Mitogen-activated Swiss mouse 3T3 RSK kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of pp90rsk activity..
88.
1991
-
Synchronous hippocampal bursting reveals network excitability defects in an epilepsy gene mutation..
88.
1991
-
Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene..
88.
1991
-
Structure and promoter activity of the gene for the erythroid transcription factor GATA-1..
88.
1991
-
Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells..
88.
1991
-
Tyrosine phosphorylation of phospholipase C induced by membrane immunoglobulin in B lymphocytes..
88.
1991
-
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production..
88.
1991
-
Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine..
88.
1991
-
Cloning and expression of a cDNA encoding human sterol carrier protein 2..
88.
1991
-
Immunoglobulins from animal models of motor neuron disease and from human amyotrophic lateral sclerosis patients passively transfer physiological abnormalities to the neuromuscular junction..
88.
1991
-
Genetic disease detection and DNA amplification using cloned thermostable ligase..
88.
1991
-
Beneficial effects of x-irradiation on recovery of lesioned mammalian central nervous tissue..
87.
1990
-
Interchangeable RNA polymerase I and II enhancers..
87.
1990
-
Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells..
87.
1990
-
Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells..
87.
1990
-
Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines..
87.
1990
-
Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene..
87.
1990
-
A biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin-resistant pneumococci..
87.
1990
-
Interleukin 1 receptor blockade attenuates the host inflammatory response..
87.
1990
-
Isolation and characterization of sulfhydryl and disulfide peptides of human apolipoprotein B-100..
87.
1990
-
Mechanism of translation of the hepadnaviral polymerase (P) gene..
87.
1990
-
Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol..
87.
1990
-
Distribution of trace levels of therapeutic gallium in bone as mapped by synchrotron x-ray microscopy..
87.
1990
-
Meander tail reveals a discrete developmental unit in the mouse cerebellum..
87.
1990
-
Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens..
87.
1990
-
Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient..
87.
1990
-
NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide..
87.
1990
-
NICER elements: a family of nerve growth factor-inducible cAMP-extinguishable retrovirus-like elements..
87.
1990
-
Transient calcium release induced by successive increments of inositol 1,4,5-trisphosphate..
87.
1990
-
Cerebellar degeneration-related antigen: a highly conserved neuroectodermal marker mapped to chromosomes X in human and mouse..
87.
1990
-
Amplified RNA synthesized from limited quantities of heterogeneous cDNA..
87.
1990
-
Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: an intracellular member of the immunoglobulin superfamily..
87.
1990
-
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance..
87.
1990
-
Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation..
87.
1990
-
Crystal structure of the antigen-binding fragment of the murine anti-arsonate monoclonal antibody 36-71 at 2.9-A resolution..
87.
1990
-
Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction..
87.
1990
-
Parathyroid hormone-related peptide gene is expressed in the mammalian central nervous system..
87.
1990
-
A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene..
86.
1989
-
Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line..
86.
1989
-
A second trans-spliced RNA leader sequence in the nematode Caenorhabditis elegans..
86.
1989
-
Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae..
86.
1989
-
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells..
86.
1989
-
Interleukin 6 induces secretion of IgG1 by coordinated transcriptional activation and differential mRNA accumulation..
86.
1989
-
On the ion selectivity in Ca-binding proteins: the cyclo(-L-Pro-Gly-)3 peptide as a model..
86.
1989
-
Regulation of food intake and body weight by cobalt porphyrins in animals..
86.
1989
-
Retroviral vector-mediated high-efficiency expression of adenosine deaminase (ADA) in hematopoietic long-term cultures of ADA-deficient marrow cells..
86.
1989
-
Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes..
86.
1989
-
ATP-dependent directional movement of rat synaptic vesicles injected into the presynaptic terminal of squid giant synapse..
86.
1989
-
Antibiotic proteins of human polymorphonuclear leukocytes..
86.
1989
-
Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium..
86.
1989
-
Identification of genes from pattern formation, tyrosine kinase, and potassium channel families by DNA amplification..
86.
1989
-
Rapid increase in enzyme and peptide mRNA in sympathetic ganglia after electrical stimulation in humans..
86.
1989
-
Decreased messenger RNA translation in herpesvirus-infected arterial cells: effects on cholesteryl ester hydrolase..
86.
1989
-
Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin..
86.
1989
-
Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans..
86.
1989
-
Bone remodeling signaled by a dihydropyridine- and phenylalkylamine-sensitive calcium channel..
86.
1989
-
Characterization of a cDNA encoding a 34-kDa Purkinje neuron protein recognized by sera from patients with paraneoplastic cerebellar degeneration..
86.
1989
-
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein..
86.
1989
-
Steroid hormones: modulators of Na+ absorption and Cl- secretion in cultured tracheal epithelia..
86.
1989
-
Chromosomes of older humans are more prone to aminopterine-induced breakage..
86.
1989
-
Partial purification and characterization of a membrane-derived factor regulating neurotransmitter phenotypic expression..
86.
1989
-
Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro..
86.
1989
-
Fate of aerosolized recombinant DNA-produced alpha 1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance..
86.
1989
-
Identification and characterization of macrophage inflammatory protein 2..
86.
1989
-
Analysis of RAS oncogene mutations in human lymphoid malignancies..
85.
1988
-
Construction of a clonable, infectious, and tumorigenic mouse mammary tumor virus provirus and a derivative genetic vector..
85.
1988
-
Epstein-Barr virus (EBV) infection of murine L cells expressing recombinant human EBV/C3d receptor..
85.
1988
-
Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line..
85.
1988
-
Identification of arginine as a precursor of endothelium-derived relaxing factor..
85.
1988
-
Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs..
85.
1988
-
Immunoglobulins from amyotrophic lateral sclerosis patients enhance spontaneous transmitter release from motor-nerve terminals..
85.
1988
-
Platelet stimulation releases a cAMP-dependent protein kinase that specifically phosphorylates a plasma protein..
85.
1988
-
An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes..
85.
1988
-
cAMP antagonizes interleukin 2-promoted T-cell cycle progression at a discrete point in early G1..
85.
1988
-
Molecular model for receptor-stimulated calcium spiking..
85.
1988
-
Presence of antibodies to a putatively immunosuppressive part of human immunodeficiency virus (HIV) envelope glycoprotein gp41 is strongly associated with health among HIV-positive subjects..
85.
1988
-
Background light and the contrast gain of primate P and M retinal ganglion cells..
85.
1988
-
Class 1 (unique) tumor antigens of human melanoma: identification of unique and common epitopes on a 90-kDa glycoprotein..
85.
1988
-
Physical association between the CD8 and HLA class I molecules on the surface of activated human T lymphocytes..
85.
1988
-
A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases..
85.
1988
-
Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells..
85.
1988
-
Influence of 5' flanking sequences on TL and H-2 expression in transfected L cells..
85.
1988
-
Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture..
85.
1988
-
Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma..
85.
1988
-
Isolation and characterization of the apical surface of polarized Madin-Darby canine kidney epithelial cells..
85.
1988
-
Leukocyte chemoattraction by 1,2-diacylglycerol..
85.
1988
-
Endothelial cell growth factor and ionophore A23187 stimulation of production of inositol phosphates in porcine aorta endothelial cells..
85.
1988
-
Heart as a target organ in 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity: decreased beta-adrenergic responsiveness and evidence of increased intracellular calcium..
85.
1988
-
Old mice recover the ability to produce IgG and high-avidity antibody following irradiation with partial bone marrow shielding..
85.
1988
-
Oligodendrocyte substratum adhesion modulates expression of adenylate cyclase-linked receptors..
85.
1988
-
An early effect of retinoic acid: cloning of an mRNA (Era-1) exhibiting rapid and protein synthesis-independent induction during teratocarcinoma stem cell differentiation..
85.
1988
-
Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy..
85.
1988
-
Low density lipoprotein receptor-independent hepatic uptake of a synthetic, cholesterol-scavenging lipoprotein: implications for the treatment of receptor-deficient atherosclerosis..
85.
1988
-
Uptake of oleate by isolated rat adipocytes is mediated by a 40-kDa plasma membrane fatty acid binding protein closely related to that in liver and gut..
85.
1988
-
X-ray Laue diffraction from crystals of xylose isomerase..
85.
1988
-
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene..
84.
1987
-
Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae..
84.
1987
-
Modulation of endogenous hormone action by recombinant human tumor necrosis factor..
84.
1987
-
Deficits in human visual spatial attention following thalamic lesions..
84.
1987
-
Plasma prorenin response to human chorionic gonadotropin in ovarian-hyperstimulated women: correlation with the number of ovarian follicles and steroid hormone concentrations..
84.
1987
-
Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP..
84.
1987
-
Nonrandom development of immunologic abnormalities after infection with human immunodeficiency virus: implications for immunologic classification of the disease..
84.
1987
-
Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration..
84.
1987
-
5'-structural analysis of genes encoding polymorphic antigens of chemically induced tumors..
84.
1987
-
Monoclonal antibody to an intracellular antigen images human melanoma transplants in nu/nu mice..
84.
1987
-
Two efficient ribosomal frameshifting events are required for synthesis of mouse mammary tumor virus gag-related polyproteins..
84.
1987
-
RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice..
84.
1987
-
Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients..
84.
1987
-
Cell-surface antigens of melanoma recognized by human monoclonal antibodies..
84.
1987
-
Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it..
84.
1987
-
Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver..
84.
1987
-
Isolation of enzyme cDNA clones by enzyme immunodetection assay: isolation of a peptide acetyltransferase..
84.
1987
-
Control of oligomeric enzyme thermostability by protein engineering..
84.
1987
-
Production of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vector..
84.
1987
-
Nucleotide sequence of a preferred maize chloroplast genome template for in vitro DNA synthesis..
84.
1987
-
Dynamic exchange of myosin molecules between thick filaments..
83.
1986
-
Isolation of yeast mutants defective in protein targeting to the vacuole..
83.
1986
-
Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA..
83.
1986
-
Immunoglobulin and T-cell receptor beta-chain gene rearrangement analysis of Hodgkin's disease: implications for lineage determination and differential diagnosis..
83.
1986
-
Isolation of components due to intracortical processing in the visual evoked potential..
83.
1986
-
Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development..
83.
1986
-
Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein..
83.
1986
-
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene..
83.
1986
-
Selective ablation of atheromas using a flashlamp-excited dye laser at 465 nm..
83.
1986
-
Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement..
83.
1986
-
Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells..
83.
1986
-
Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients..
83.
1986
-
Chromosomal breakpoints and structural alterations of the c-myc locus differ in endemic and sporadic forms of Burkitt lymphoma..
83.
1986
-
Human brain glial cells synthesize thrombospondin..
83.
1986
-
Specificity analysis of human monoclonal antibodies reactive with cell surface and intracellular antigens..
83.
1986
-
Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium..
83.
1986
-
Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule..
83.
1986
-
Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity..
83.
1986
-
Plasma high density lipoprotein is increased in man when low density lipoprotein (LDL) is lowered by LDL-pheresis..
83.
1986
-
Functional channel formation associated with cytotoxic T-cell granules..
83.
1986
-
Molecular cloning of the neu gene: absence of gross structural alteration in oncogenic alleles..
83.
1986
-
Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide..
82.
1985
-
Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b..
82.
1985
-
Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product..
82.
1985
-
Molecular cloning and expression of partial cDNAs and deduced amino acid sequence of a carboxyl-terminal fragment of human apolipoprotein B-100..
82.
1985
-
Regulation of a ribosomal protein S6 kinase activity by the Rous sarcoma virus transforming protein, serum, or phorbol ester..
82.
1985
-
Cell surface antigen of human neuroblastomas is related to nuclear antigen of normal cells..
82.
1985
-
Structural analysis of TL genes of the mouse..
82.
1985
-
Restricted homology between human alpha 1 type IV and other procollagen chains..
82.
1985
-
Two-codon insertion mutagenesis of plasmid genes by using single-stranded hexameric oligonucleotides..
82.
1985
-
A frameshift mutation in the pre-S region of the human hepatitis B virus genome allows production of surface antigen particles but eliminates binding to polymerized albumin..
82.
1985
-
Specificity analysis of mouse monoclonal antibodies defining cell surface antigens of human renal cancer..
82.
1985
-
T-cell receptor gene rearrangements as markers of lineage and clonality in T-cell neoplasms..
82.
1985
-
Cardiac dysfunction caused by purified human C3a anaphylatoxin..
82.
1985
-
Interleukin 2 regulates its own receptors..
82.
1985
-
Intracellular free calcium levels are reduced in mitotic Pt K2 epithelial cells..
82.
1985
-
Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma..
82.
1985
-
Proapolipoprotein A-I conversion kinetics in vivo in human and in rat..
82.
1985
-
The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin..
82.
1985
-
Lipoprotein lipase is produced, regulated, and functional in rat brain..
81.
1984
-
Activation of a translocated c-myc gene: role of structural alterations in the upstream region..
81.
1984
-
Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector..
81.
1984
-
A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration..
81.
1984
-
Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro..
81.
1984
-
Phorbol ester, serum, and rous sarcoma virus transforming gene product induce similar phosphorylations of ribosomal protein S6..
81.
1984
-
Somatic cell genetic analysis of human cell surface antigens: chromosomal assignments and regulation of expression in rodent-human hybrid cells..
81.
1984
-
The cloned genome of ground squirrel hepatitis virus is infectious in the animal..
81.
1984
-
Adenosine-dependent activation of tyrosine hydroxylase is defective in adenosine kinase-deficient PC12 cells..
81.
1984
-
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma..
81.
1984
-
Intramolecular dislocation of the COOH terminus of the lac carrier protein in reconstituted proteoliposomes..
81.
1984
-
Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2..
81.
1984
-
Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria..
81.
1984
-
T-cell-mediated cytotoxicity against autologous malignant melanoma: analysis with interleukin 2-dependent T-cell cultures..
81.
1984
-
beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects..
81.
1984
-
Neurotrophic effects of hippocampal extracts on medial septal nucleus in vitro..
81.
1984
-
Transformation by Rous sarcoma virus prevents acetylcholine receptor clustering on cultured chicken muscle fibers..
81.
1984
-
T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells..
81.
1984
-
Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway..
81.
1984
-
Chaotic behavior in dopamine neurodynamics..
81.
1984
-
Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes..
81.
1984
-
Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors..
81.
1984
-
An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast..
80.
1983
-
Directional transport and integration of donor DNA in Haemophilus influenzae transformation..
80.
1983
-
Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain..
80.
1983
-
Nutrition-endocrine interactions: induction of reciprocal changes in the delta 4-5 alpha-reduction of testosterone and the cytochrome P-450-dependent oxidation of estradiol by dietary macronutrients in man..
80.
1983
-
Transformasomes: specialized membranous structures that protect DNA during Haemophilus transformation..
80.
1983
-
A small region of the mouse mammary tumor virus long terminal repeat confers glucocorticoid hormone regulation on a linked heterologous gene..
80.
1983
-
Isolation of cDNA clones specific for collagen IV and laminin from mouse teratocarcinoma cells..
80.
1983
-
Importance of secondary structure in the signal sequence for protein secretion..
80.
1983
-
Phenomenon of formation of giant fat-containing cells in human bone marrow cultures induced by human serum factor: normal and leukemic patterns..
80.
1983
-
Structure of iron superoxide dismutase from Pseudomonas ovalis at 2.9-A resolution..
80.
1983
-
Evidence for an interleukin-independent pathway for human lymphocyte activation..
80.
1983
-
Selective phosphorylation of the IgE receptor in antigen-stimulated rat mast cells..
80.
1983
-
Transduction of a cellular oncogene: the genesis of Rous sarcoma virus..
80.
1983
-
Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain..
80.
1983
-
Generation of human monoclonal antibodies reactive with cellular antigens..
80.
1983
-
Genes for catecholamine biosynthesis: cloning by expression and identification of the cDNA for rat dopamine beta-hydroxylase..
80.
1983
-
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma..
80.
1983
-
Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia..
80.
1983
-
Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix..
80.
1983
-
Immunohistochemical distribution of dynorphin B in rat brain: relation to dynorphin A and alpha-neo-endorphin systems..
80.
1983
-
Transformation-sensitive protein associated with the cell substratum of chicken embryo fibroblasts..
80.
1983
-
Opiates and classical conditioning: selective abolition of conditioned responses by activation of opiate receptors within the central nervous system..
79.
1982
-
Thyroid hormone regulation of heme oxidation in the liver..
79.
1982
-
Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA..
79.
1982
-
Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K..
79.
1982
-
De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells..
79.
1982
-
Immunohistochemical distribution of alpha-neo-endorphin/dynorphin neuronal systems in rat brain: evidence for colocalization..
79.
1982
-
Receptor-mediated endocytosis of diphtheria toxin by cells in culture..
79.
1982
-
Staphylococcal plasmids that replicate and express erythromycin resistance in both Streptococcus pneumoniae and Escherichia coli..
79.
1982
-
Abnormal humoral immune responses in peripheral blood lymphocyte cultures of bone marrow transplant recipients..
79.
1982
-
Membrane antigen on Epstein--Barr virus-infected human B cells recognized by a monoclonal antibody..
79.
1982
-
The cytochrome P-450-depleted animal: an experimental model for in vivo studies in chemical biology..
79.
1982
-
Purification of two subspecies of human gamma (immune) interferon..
79.
1982
-
Nonrandom association of polymorphic restriction sites in the beta-globin gene cluster..
79.
1982
-
alpha-Actinin and membrane glycoprotein IIIa are different proteins in human blood platelets..
79.
1982
-
DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning..
78.
1981
-
The behavioral effects of phencyclidines may be due to their blockade of potassium channels..
78.
1981
-
Plasma cell dyscrasia and peripheral neuropathy: identification of the myelin antigens that react with human paraproteins..
78.
1981
-
Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases..
78.
1981
-
Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation..
78.
1981
-
Cellular homologue (c-src) of the transforming gene of Rous sarcoma virus: isolation, mapping, and transcriptional analysis of c-src and flanking regions..
78.
1981
-
Direct demonstration of a correspondence between the dopamine islands and acetylcholinesterase patches in the developing striatum..
78.
1981
-
Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins..
78.
1981
-
A Rous sarcoma virus provirus is flanked by short direct repeats of a cellular DNA sequence present in only one copy prior to integration..
78.
1981
-
Antibodies reactive with murine mammary tumor virus in sera of patients with breast cancer: geographic and family studies..
78.
1981
-
Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins..
78.
1981
-
Partial purification and characterization of human gamma (immune) interferon..
78.
1981
-
A brain membrane protein similar to the rat src gene product..
78.
1981
-
Cultured muscle from myotonic muscular dystrophy patients: altered membrane electrical properties..
78.
1981
-
Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements..
78.
1981
-
Lateral distribution and diffusion of the C3b receptor of complement, HLA antigens, and lipid probes in peripheral blood leukocytes..
77.
1980
-
Production of auto-anti-idiotypic antibody during the normal immune response: changes in the auto-anti-idiotypic antibody response and the idiotype repertoire associated with aging..
77.
1980
-
Purification of the regulatory component of adenylate cyclase..
77.
1980
-
Structural analysis of factor VIII antigen in von Willebrand disease..
77.
1980
-
Catecholamine biosynthetic enzymes are expressed in replicating cells of the peripheral but not the central nervous system..
77.
1980
-
Cell surface antigens of human malignant melanoma: definition of six antigenic systems with mouse monoclonal antibodies..
77.
1980
-
Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7..
77.
1980
-
Radiometric analysis of biological oxidations in man: sex differences in estradiol metabolism..
77.
1980
-
Regulation of the production of secretory proteins: intracellular degradation of newly synthesized "defective" collagen..
77.
1980
-
Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus..
77.
1980
-
Serological survey of normal humans for natural antibody to cell surface antigens of melanoma..
77.
1980
-
Activation of lecithin:cholesterol acyltransferase by a synthetic model lipid-associating peptide..
77.
1980
-
Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts..
77.
1980
-
Alloantigen-induced T-cell proliferation: Lyt phenotype of responding cells and blocking of proliferation by Lyt antisera..
77.
1980
-
Plasmids containing insertion elements are potential transposons..
77.
1980
-
Antibodies to Epstein-Barr virus-determined antigens in normal subjects and in patients with seropositive rheumatoid arthritis..
76.
1979
-
Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits..
76.
1979
-
Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane..
76.
1979
-
Manganese and zinc blockade of enzyme induction: studies with microsomal heme oxygenase..
76.
1979
-
beta-Endorphin: analgesic and hormonal effects in humans..
76.
1979
-
Topological organization of proteins in an intracellular secretory organelle: the synaptic vesicle..
76.
1979
-
Definition of a unique cell surface antigen of mouse leukemia RL male 1 by cell-mediated cytotoxicity..
76.
1979
-
Cyclized dipeptide model for a beta-bend..
76.
1979
-
Structural analysis of human platelet membrane glycoprotein I complex..
76.
1979
-
Virolysis of mouse mammary tumor virus by sera from breast cancer patients..
76.
1979
-
Induction of prostaglandin E synthesis in normal and neoplastic macrophages: role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation..
76.
1979
-
Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera..
76.
1979
-
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src)..
76.
1979
-
Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes..
76.
1979
-
Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: genetic model for immunodeficiency disease..
76.
1979
-
Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells..
76.
1979
-
Nonlinear systems analysis: comparison of white noise and sum of sinusoids in a biological system..
76.
1979
-
Autosomal locus regulates inverse relationship between sialic acid content and capacity of mouse erythrocytes to activate human alternative complement pathway..
75.
1978
-
Expression of Ia-like antigens on cultured human malignant melanoma cell lines..
75.
1978
-
Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein..
75.
1978
-
Appearance of beta-endorphin-like immunoreactivity in human ventricular cerebrospinal fluid upon analgesic electrical stimulation..
75.
1978
-
Asymmetric budding of viruses in epithelial monlayers: a model system for study of epithelial polarity..
75.
1978
-
Serological analysis of cell surface antigens of malignant human brain tumors..
75.
1978
-
Formation of high density lipoprotein2-like particles during lipolysis of very low density lipoproteins in vitro..
75.
1978
-
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates..
75.
1978
-
Membrane sialic acid on target particles modulates their phagocytosis by a trypsin-sensitive mechanism on human monocytes..
75.
1978
-
Induction of murine erythroleukemia differentiation by actinomycin D..
75.
1978
-
Mapping of linear and circular forms of mouse mammary tumor virus DNA with restriction endonucleases: evidence for a large specific deletion occurring at high frequency during circularization..
75.
1978
-
Regulation by membrane sialic acid of beta1H-dependent decay-dissociation of amplification C3 convertase of the alternative complement pathway..
75.
1978
-
Expression of collagen biosynthetic activities in lymphocytic cells..
75.
1978
-
Antagonism of histamine-activated adenylate cyclase in brain by D-lysergic acid diethylamide..
74.
1977
-
Identification of the recA (tif) gene product of Escherichia coli..
74.
1977
-
Activation of lipoprotein lipase by native and synthetic fragments of human plasma apolipoprotein C-II..
74.
1977
-
beta-Lipotropin: localization of cells and axons in rat brain by immunocytochemistry..
74.
1977
-
Homology between a prolyl hydroxylase subunit and a tissue protein that crossreacts immunologically with the enzyme..
74.
1977
-
Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells..
74.
1977
-
Theories of quasi-linkage and "affinity": some implications for population structure..
74.
1977
-
Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA..
74.
1977
-
Nonlinear analysis of cat retinal ganglion cells in the frequency domain..
74.
1977
-
Serotonergic neurons in the peripheral nervous system: identification in gut by immunohistochemical localization of tryptophan hydroxylase..
74.
1977
-
Accelerated degradation of acetylcholine receptor from cultured rat myotubes with myasthenia gravis sera and globulins..
74.
1977
-
Primary structure of very low density apolipoprotein C-II of human plasma..
74.
1977
-
Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: blockade of metal effects by thiols..
74.
1977
-
Activation of the alternative complement pathway due to resistance of zymosan-bound amplification convertase to endogenous regulatory mechanisms..
74.
1977
-
Differential effects of chemical inducers on expression of beta globin genes in murine erythroleukemia cells..
74.
1977
-
Endotoxin-induced serum factor controlling differentiation of bone-marrow-derived lymphocytes..
74.
1977
-
Granulocyte collagenase: selective digestion of type I relative to type III collagen..
74.
1977
-
Three-dimensional structure of neurotoxin a from venom of the Philippines sea snake..
74.
1977
-
Thymic activity in severe combined immunodeficiency diseases..
74.
1977
-
Inhibitors of genetic recombination in pneumococci..
74.
1977
-
Interaction of tetraiodofluorescein with a modified form of aspartate transcarbamylase..
74.
1977
-
Selenium regulation of hepatic heme metabolism: induction of delta-aminolevulinate synthase and heme oxygenase..
73.
1976
-
Recombination promoted by superhelical DNA and the recA gene of Escherichia coli..
73.
1976
-
Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells..
73.
1976
-
Control of the amplification convertase of complement by the plasma protein beta1H..
73.
1976
-
Suppression of lytic effect of beta lactams on Escherichia coli and other bacteria..
73.
1976
-
Interactions between nutritional factors and drug biotransformations in man..
73.
1976
-
Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver..
73.
1976
-
The solid phase synthesis of a protein activator for lecithin-cholesterol acyltransferase corresponding to human plasma apoC-I..
73.
1976
-
Ontogeny of lymphocyte subpopulations in human fetal liver..
73.
1976
-
Demonstration of non-functional beta-globin mRNA in homozygous beta (0) thalassemia..
72.
1975
-
Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis..
72.
1975
-
Purification of RNA-instructed DNA polymerase from human leukemic spleens..
72.
1975
-
Brain tryptophan hydroxylase: purification of, production of antibodies to, and cellular and ultrastructural localization in serotonergic neurons of rat midbrain..
72.
1975
-
Ribonuclease-sensitive DNA-synthesizing complex in human sperm heads and seminal fluid..
72.
1975
-
Properdin: initiation of alternative complement pathway..
72.
1975
-
Model for regulation of Escherichia coli DNA repair functions..
72.
1975
-
Uptake of homologous single-stranded fragments by superhelical DNA: a possible mechanism for initiation of genetic recombination..
72.
1975
-
Lipoteichoic acid: a specific inhibitor of autolysin activity in Pneumococcus..
72.
1975
-
Ultrastructural localization of tyrosine hydroxylase in noradrenergic neurons of brain..
72.
1975
-
Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity..
71.
1974
-
Enhancement of tumor growth by graft-versus-host reaction..
71.
1974
-
Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in enucleated cells after infection by avian sarcoma virus..
71.
1974
-
The primary structure of high density apolipoprotein-glutamine-I..
71.
1974
-
Lung collagen heterogeneity..
71.
1974
-
Effects of dialyzable transfer factor in patients with breast cancer..
71.
1974
-
Enhancement of RNA synthesis in avian liver cell cultures by a 5beta-steroid metabolite during induction of delta-aminolevulinate synthase..
71.
1974
-
Synthesis of von Willebrand factor by cultured human endothelial cells..
71.
1974
-
Early stages in DNA binding and uptake during genetic transformation of pneumococci..
71.
1974
-
A microassay for uroporphyrinogen I synthase, one of three abnormal enzyme activities in acute intermittent porphyria, and its application to the study of the genetics of this disease..
71.
1974
-
Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy..
71.
1974
-
Acetylcholine-like molecular arrangement in psychomimetic anticholinergic drugs..
70.
1973
-
Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts..
70.
1973
-
Chemical synthesis and biochemical properties of peptide fragments of apolipoprotein-alanine..
70.
1973
-
Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular dystrophy..
70.
1973
-
Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver..
70.
1973
-
Assays for porphyrins, delta-aminolevulinic-acid dehydratase, and porphyrinogen synthetase in microliter samples of whole blood: applications to metabolic defects involving the heme pathway..
69.
1972
-
Genetic variation in activity of enzymes involved in synthesis of catecholamines..
69.
1972
-
Initiation of hemoglobin synthesis: comparison of model reactions that use artificial templates with those using natural messenger RNA..
69.
1972
-
Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs (reassociation kinetics-RNA tumor viruses-gas antigen-Rous sarcoma virus, chick cells)..
69.
1972
-
Abnormal autolytic enzyme in a pneumococus with altered teichoic acid composition..
68.
1971
-
Control by cesium and intermediates of the citric acid cycle of extracellular ribonuclease and other enzymes involved in the assimilation of nitrogen..
68.
1971
-
Requirement for GTP in the initiation process on reticulocyte ribosomes and ribosomal subunits..
68.
1971
-
DNA uptake during genetic transformation and the growing zone of the cell envelope..
68.
1971
-
Initial dipeptide formation in hemoglobin biosynthesis..
68.
1971
-
Stimulation of mammalian erythropoiesis by 5beta-H steroid metabolites..
65.
1970
-
Electron spin resonance studies of lipid-protein interaction in human serum lipoproteins..
65.
1970
-
Demonstration of delayed hypersensitivity to soluble antigens of chemically induced tumors by inhibition of macrophage migration..
64.
1969
-
Recent studies on the structure of human serum low-and high-density lipoproteins..
64.
1969
-
The occurrence of substances in human plasma capable of inducing the enzyme delta-aminolevulinate synthetase in liver cells..
64.
1969
-
THE INDUCTION OF delta-AMINOLEVULINIC ACID SYNTHETASE in vivo IN CHICK EMBRYO LIVER BY NATURAL STEROIDS..
61.
1968
-
An autoradiographic study of genetic transformation..
60.
1968
-
Observations on the conformation of human beta lipoprotein: evidence for the occurrence of beta structure..
60.
1968
-
Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids..
58.
1967
-
Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites..
57.
1967
-
On the nature of the pneumococcal activator substance..
55.
1966
-
THE MECHANISM OF BACTERIAL FRAGILITY PRODUCED BY 5-FLUOROURACIL: THE ACCUMULATION OF CELL WALL PRECURSORS..
46.
1960
-
AN EARLY PHASE IN THE BACTERICIDAL ACTION OF 5-FLUOROURACIL ON E. COLI K(12). OSMOTIC IMBALANCE..
45.
1959
-
Correction to Supporting Information for Talantova et al., Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss..
112.
2015
-
Correction..
112.
2015
-
High-speed atomic force microscopy tracks the dynamic parts of the ribosome.
2021
-
An approach that someday may boost testosterone biosynthesis in males with late-onset hypogonadism (low testosterone).
2019
-
Stress response regulation and the hemodynamic response.
2018
-
Collusion between neutralizing antibodies and other immune factions in the destruction of adenoviral vectors.
2018
-
LSD1: A single target to combat lineage plasticity in lethal prostate cancer.
2018
-
Modulating membrane binding of α-synuclein as a therapeutic strategy.
2017
-
Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action.
2016
-
Advanced neuroendocrine prostate tumors regress to stemness.
2015
-
Fuzzy universality of probability judgment.
2014
-
RABbing cancer the wrong way.
2014
-
Parsing out the embryonic origin of subplate cell-type diversity.
2014
-
Microbial metabolites control gut inflammatory responses.
2014
-
Molecular basis of severe malaria.
2012
-
A target for antiangiogenic therapy: vascular endothelium derived from glioblastoma.
2011
-
End game: getting the most out of microRNAs.
2011
-
A big role for small RNAs in influenza virus replication.
2010
-
Further evidence of the safety of assisted reproductive technologies.
2007
-
Circulating tumor cells in breast cancer: Advanced tools for "tailored" therapy?
2006
-
STAT3: a multifaceted oncogene.
2006
-
The real estate of cardiac signaling: location, location, location.
2006
-
Coupling neurotrophins to cell migration through selective guanine nucleotide exchange factor activation.
2005
-
Reverse transcriptase at bacterial telomeres.
2004
-
Kiss-and-run, fuse-pinch-and-linger, fuse-and-collapse: the life and times of a neurosecretory granule.
2003
-
Flow, NO, and atherogenesis.
2003
-
Flotillas of lipid rafts fore and aft.
2001
-
Intergeneric poliovirus recombinants for the treatment of malignant glioma.
2000
-
Chemistry and biology.
2000
-
Physiological reactions of nitric oxide and hemoglobin: a radical rethink.
1999
-
Transplantation tolerance: fooling mother nature.
1996
-
What the nose knows: new understandings of Neanderthal upper respiratory tract specializations.
1996
-
Reply to Nagle et al.: The universal stiffening effects of cholesterol on lipid membranes.
2021
-
Ca2+/CaM interaction with voltage-gated Na+ channels.
2019
-
Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus.
2019
-
Reply to Spreng et al.: Multiecho fMRI denoising does not remove global motion-associated respiratory signals.
2019
-
Hypomethylation, endogenous retrovirus expression, and interferon signaling in testicular germ cell tumors.
2018
-
Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas.
2008
-
The epidemiology of AIDS in Haiti refutes the claims of Gilbert et al.
2008
-
ADD-1 provides major new insight into the mechanism of insulin action.
1999
-
Telomerase and retrotransposons: reverse transcriptases that shaped genomes.
2011
-
Uncensored exchange of scientific results..
100.
2003
-
A scientific theory of gist communication and misinformation resistance, with implications for health, education, and policy.
2020
-
Quantitative descriptions of generalized arousal, an elementary function of the vertebrate brain.
2011
-
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
2009
-
Stem cells of the skin epithelium.
2003
-
Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation.
2001
-
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens.
2000
-
The neuroimaging of human brain function.
1998
-
Attention: the mechanisms of consciousness.
1994
-
Signal transduction via the MAP kinases: proceed at your own RSK.
1993
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